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The map label for this gene is hslO

Identifier: 126176394

GI number: 126176394

Start: 4929252

End: 4930112

Strand: Direct

Name: hslO

Synonym: Sbal_4209

Alternate gene names: 126176394

Gene position: 4929252-4930112 (Clockwise)

Preceding gene: 126176393

Following gene: 126176395

Centisome position: 96.14

GC content: 48.55

Gene sequence:

>861_bases
ATGAACCAAGATACTTTACACCGCTACTTGTTCGACAATGCCGATGTGCGTGGTGAACTGGTGCAGTTACAAGACAGCTA
TCAACAAGTGATCAGCGCCCAAGAATATCCAGCCGTACTGCAAGTATTACTGGGTGAATTAATGGCGGCCACCTCACTAT
TAACGGCGACATTGAAATTTAGCGGCGATATCAGCGTACAGTTACAGGGCAATGGTCCTGTTTCTTTAGCGGTGATCAAC
GGTAACAATCTACAAGAGTTACGCGGTGTGGCTCGCTGGAATGCAGAACTAGCCGATGATGCCAGCCTTACCGATCTTTT
CGGTCAGGGCTATATGGTCATCACCTTAACACCCGACGAAGGTGAACGCTACCAAGGTGTGGTCGCACTCGACAAGCCAA
CGCTAGCGGCCTGTGTTGAAGAATACTTCAATCAATCTGAACAGTTACCAACAGGCATTTGGTTATTTGCCGACGGCAAA
CAAGCGGCGGGCATGTTCCTACAAATTTTGCCAAGTAAAGAAGATCACAACCCAGACTTCGAGCACTTGAGCCAACTGAC
GTCGACTATCAAGGCCGAAGAGCTGTTCACACTCGACGCTGAAAGCGTGTTACATCGCCTATATCATCAGGAAGAAGTGC
GCCTATTCGATCCTATCGATGTGAGCTTTAAGTGTACTTGCTCCCATGAACGCAGTGCCGGCGCGATCAAGACCTTAGAT
CAAGCGGAAATCGAAGCTATTCTCGCCGAAGACGGCAAGATCGAAATGGGCTGCGAATATTGCCACGCAAAATACATTTT
TGATGCCATAGACGTAGCCGCATTATTTGCGAACGGTCAGACGTCAACGACCCAGCAATAA

Upstream 100 bases:

>100_bases
GTCTCCACATGCTTAATAACCCGATACCCGATCAGAAACCAGATAAAAAGCAACGACGCCAGCTCATGCGCTTTAAAGAC
CTTTAACAGTGAGATACACG

Downstream 100 bases:

>100_bases
TCGGTTAACCGGTTCATCAAAGCTAAACAATATGGGCGCCCGATTCGGCGCCCATTTTTTATTCATCCCCACAATCCCCT
CACACATTGCACTCGGCTTA

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MNQDTLHRYLFDNADVRGELVQLQDSYQQVISAQEYPAVLQVLLGELMAATSLLTATLKFSGDISVQLQGNGPVSLAVIN
GNNLQELRGVARWNAELADDASLTDLFGQGYMVITLTPDEGERYQGVVALDKPTLAACVEEYFNQSEQLPTGIWLFADGK
QAAGMFLQILPSKEDHNPDFEHLSQLTSTIKAEELFTLDAESVLHRLYHQEEVRLFDPIDVSFKCTCSHERSAGAIKTLD
QAEIEAILAEDGKIEMGCEYCHAKYIFDAIDVAALFANGQTSTTQQ

Sequences:

>Translated_286_residues
MNQDTLHRYLFDNADVRGELVQLQDSYQQVISAQEYPAVLQVLLGELMAATSLLTATLKFSGDISVQLQGNGPVSLAVIN
GNNLQELRGVARWNAELADDASLTDLFGQGYMVITLTPDEGERYQGVVALDKPTLAACVEEYFNQSEQLPTGIWLFADGK
QAAGMFLQILPSKEDHNPDFEHLSQLTSTIKAEELFTLDAESVLHRLYHQEEVRLFDPIDVSFKCTCSHERSAGAIKTLD
QAEIEAILAEDGKIEMGCEYCHAKYIFDAIDVAALFANGQTSTTQQ
>Mature_286_residues
MNQDTLHRYLFDNADVRGELVQLQDSYQQVISAQEYPAVLQVLLGELMAATSLLTATLKFSGDISVQLQGNGPVSLAVIN
GNNLQELRGVARWNAELADDASLTDLFGQGYMVITLTPDEGERYQGVVALDKPTLAACVEEYFNQSEQLPTGIWLFADGK
QAAGMFLQILPSKEDHNPDFEHLSQLTSTIKAEELFTLDAESVLHRLYHQEEVRLFDPIDVSFKCTCSHERSAGAIKTLD
QAEIEAILAEDGKIEMGCEYCHAKYIFDAIDVAALFANGQTSTTQQ

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=287, Percent_Identity=56.4459930313589, Blast_Score=333, Evalue=1e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_SHEB2 (B8E3S8)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002356113.1
- ProteinModelPortal:   B8E3S8
- SMR:   B8E3S8
- GeneID:   7086751
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_0149
- HOGENOM:   HBG296531
- OMA:   AMTIDQG
- ProtClustDB:   PRK00114
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- InterPro:   IPR023212
- Gene3D:   G3DSA:1.10.287.480
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 31599; Mature: 31599

Theoretical pI: Translated: 4.12; Mature: 4.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQDTLHRYLFDNADVRGELVQLQDSYQQVISAQEYPAVLQVLLGELMAATSLLTATLKF
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEE
SGDISVQLQGNGPVSLAVINGNNLQELRGVARWNAELADDASLTDLFGQGYMVITLTPDE
CCCEEEEEECCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHCCCEEEEEEECCC
GERYQGVVALDKPTLAACVEEYFNQSEQLPTGIWLFADGKQAAGMFLQILPSKEDHNPDF
CCCEEEEEEECCCHHHHHHHHHHCCCCCCCCEEEEEECCCHHHCEEEEEECCCCCCCCCH
EHLSQLTSTIKAEELFTLDAESVLHRLYHQEEVRLFDPIDVSFKCTCSHERSAGAIKTLD
HHHHHHHHHHHHHHHEEECHHHHHHHHHHHCCCEEECCCCCEEEEEECCCCCCCHHHHHH
QAEIEAILAEDGKIEMGCEYCHAKYIFDAIDVAALFANGQTSTTQQ
HHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNQDTLHRYLFDNADVRGELVQLQDSYQQVISAQEYPAVLQVLLGELMAATSLLTATLKF
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEE
SGDISVQLQGNGPVSLAVINGNNLQELRGVARWNAELADDASLTDLFGQGYMVITLTPDE
CCCEEEEEECCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHCCCEEEEEEECCC
GERYQGVVALDKPTLAACVEEYFNQSEQLPTGIWLFADGKQAAGMFLQILPSKEDHNPDF
CCCEEEEEEECCCHHHHHHHHHHCCCCCCCCEEEEEECCCHHHCEEEEEECCCCCCCCCH
EHLSQLTSTIKAEELFTLDAESVLHRLYHQEEVRLFDPIDVSFKCTCSHERSAGAIKTLD
HHHHHHHHHHHHHHHEEECHHHHHHHHHHHCCCEEECCCCCEEEEEECCCCCCCHHHHHH
QAEIEAILAEDGKIEMGCEYCHAKYIFDAIDVAALFANGQTSTTQQ
HHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA