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The map label for this gene is coaA

Identifier: 126176358

GI number: 126176358

Start: 4880533

End: 4881483

Strand: Direct

Name: coaA

Synonym: Sbal_4173

Alternate gene names: 126176358

Gene position: 4880533-4881483 (Clockwise)

Preceding gene: 126176327

Following gene: 126176361

Centisome position: 95.19

GC content: 45.53

Gene sequence:

>951_bases
ATGACTTCTAAAAATTCAATTCAAAAAGCACTCTATCTCGCCTTTGAGCGCCTGCAATGGTCTGAGTTACGAGATTCAGT
GCCGCTGACGCTGAGTGAGCAAGACTTGGAAAACCTTAGAGGCATAAATGAGAAGATATCCTTATCGGAAGTCACTGATA
TTTACCTTCCCCTTAGCCGGCTACTCAATTTAATTGTCAAAGCTAAGCAGCAACGTGGCTTAGTGGTTGATGAGTTCCTT
GGGCAAAAACCATCAAGAAGCCCTTACATTATTAGTATTGCCGGCAGTGTCGCCGTCGGCAAAAGTACCACAGCGCGTAT
CTTGCAAGCCTTGCTACGGCATTGGCCTGAGCACCCCAAGGTCGATCTAGTCACAACGGATGGCTTTTTGTATCCACTGG
CAGACTTGAAGCGTAAAGGGTTGTTACAACGTAAGGGATTTCCAGAAAGCTACGATATGAAAATGCTGGTTGAGTTTATC
TCAGCAGTAAAATCTGGCCAACCCCATGTGAAAGCGCCTATCTATTCACACGTCACCTATGACCGTGTTAAGAATCAGCA
CCAAACCGTTTCTCAGCCAGACATATTAATTTTGGAAGGCTTGAATGTACTGCAGACTGGGCTAGACTCCCCCGTCGATA
CCCGTCGTCCTTTTGTCTCCGATTTTGTCGACTTTTCTATTTATGTCGATGCGGAAGAGCCGTTACTCAAACAATGGTAC
AAAGAACGCTTCTTGCAATTCCGCTCTGGCGCCTTCAGTGACAAGAAATCCTATTTCCATCACTATTCGTCGCTAACCGA
TGATGAAGCCAATACCATTGCCGCCAATATTTGGGACACGATTAACGGTCCCAACCTGCAATTGAATATTCAACCGACCC
GTGAAAGAGCTCATTTGATCTTGCAAAAAGGTCAGGATCATTTGATGTCCCACGTACTGATGCGCAAATAG

Upstream 100 bases:

>100_bases
TACATCAAACGACGACGGAAACACGACTGCAATCACCCATTTAGTATTGTTCCGAATAATCTCATAGTGTACTGTGCCTT
TCCTAAGCTGAGGAAAGCCA

Downstream 100 bases:

>100_bases
TTTTCTGTAAAATAGTCTCTTGGGTGCTTAGCGGGCCCTTAAGCTAATTTCACCGCCGATAAATGCTTGCACACCGTCGG
CGGTTTCGAGCAATACCGCA

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTSKNSIQKALYLAFERLQWSELRDSVPLTLSEQDLENLRGINEKISLSEVTDIYLPLSRLLNLIVKAKQQRGLVVDEFL
GQKPSRSPYIISIAGSVAVGKSTTARILQALLRHWPEHPKVDLVTTDGFLYPLADLKRKGLLQRKGFPESYDMKMLVEFI
SAVKSGQPHVKAPIYSHVTYDRVKNQHQTVSQPDILILEGLNVLQTGLDSPVDTRRPFVSDFVDFSIYVDAEEPLLKQWY
KERFLQFRSGAFSDKKSYFHHYSSLTDDEANTIAANIWDTINGPNLQLNIQPTRERAHLILQKGQDHLMSHVLMRK

Sequences:

>Translated_316_residues
MTSKNSIQKALYLAFERLQWSELRDSVPLTLSEQDLENLRGINEKISLSEVTDIYLPLSRLLNLIVKAKQQRGLVVDEFL
GQKPSRSPYIISIAGSVAVGKSTTARILQALLRHWPEHPKVDLVTTDGFLYPLADLKRKGLLQRKGFPESYDMKMLVEFI
SAVKSGQPHVKAPIYSHVTYDRVKNQHQTVSQPDILILEGLNVLQTGLDSPVDTRRPFVSDFVDFSIYVDAEEPLLKQWY
KERFLQFRSGAFSDKKSYFHHYSSLTDDEANTIAANIWDTINGPNLQLNIQPTRERAHLILQKGQDHLMSHVLMRK
>Mature_315_residues
TSKNSIQKALYLAFERLQWSELRDSVPLTLSEQDLENLRGINEKISLSEVTDIYLPLSRLLNLIVKAKQQRGLVVDEFLG
QKPSRSPYIISIAGSVAVGKSTTARILQALLRHWPEHPKVDLVTTDGFLYPLADLKRKGLLQRKGFPESYDMKMLVEFIS
AVKSGQPHVKAPIYSHVTYDRVKNQHQTVSQPDILILEGLNVLQTGLDSPVDTRRPFVSDFVDFSIYVDAEEPLLKQWYK
ERFLQFRSGAFSDKKSYFHHYSSLTDDEANTIAANIWDTINGPNLQLNIQPTRERAHLILQKGQDHLMSHVLMRK

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family

Homologues:

Organism=Escherichia coli, GI1790409, Length=316, Percent_Identity=59.4936708860759, Blast_Score=383, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAA_SHEB2 (B8EBM0)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002359967.1
- ProteinModelPortal:   B8EBM0
- SMR:   B8EBM0
- GeneID:   7089689
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_4071
- HOGENOM:   HBG732538
- OMA:   GLNVLQP
- ProtClustDB:   PRK05439
- GO:   GO:0005737
- HAMAP:   MF_00215
- InterPro:   IPR004566
- InterPro:   IPR006083
- PANTHER:   PTHR10285:SF7
- PIRSF:   PIRSF000545
- TIGRFAMs:   TIGR00554

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.33

Molecular weight: Translated: 36141; Mature: 36010

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSKNSIQKALYLAFERLQWSELRDSVPLTLSEQDLENLRGINEKISLSEVTDIYLPLSR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LLNLIVKAKQQRGLVVDEFLGQKPSRSPYIISIAGSVAVGKSTTARILQALLRHWPEHPK
HHHHHHHHHHHCCCCHHHHHCCCCCCCCEEEEECCCEEECCCHHHHHHHHHHHHCCCCCC
VDLVTTDGFLYPLADLKRKGLLQRKGFPESYDMKMLVEFISAVKSGQPHVKAPIYSHVTY
EEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHH
DRVKNQHQTVSQPDILILEGLNVLQTGLDSPVDTRRPFVSDFVDFSIYVDAEEPLLKQWY
HHHHHHHCCCCCCCEEEECCHHHHHHCCCCCCCCCCCHHHHHCCEEEEECCCCHHHHHHH
KERFLQFRSGAFSDKKSYFHHYSSLTDDEANTIAANIWDTINGPNLQLNIQPTRERAHLI
HHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHEEHHHHHCCCCCCEEEEECCCHHHHHHH
LQKGQDHLMSHVLMRK
HHCCHHHHHHHHHHCC
>Mature Secondary Structure 
TSKNSIQKALYLAFERLQWSELRDSVPLTLSEQDLENLRGINEKISLSEVTDIYLPLSR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LLNLIVKAKQQRGLVVDEFLGQKPSRSPYIISIAGSVAVGKSTTARILQALLRHWPEHPK
HHHHHHHHHHHCCCCHHHHHCCCCCCCCEEEEECCCEEECCCHHHHHHHHHHHHCCCCCC
VDLVTTDGFLYPLADLKRKGLLQRKGFPESYDMKMLVEFISAVKSGQPHVKAPIYSHVTY
EEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHH
DRVKNQHQTVSQPDILILEGLNVLQTGLDSPVDTRRPFVSDFVDFSIYVDAEEPLLKQWY
HHHHHHHCCCCCCCEEEECCHHHHHHCCCCCCCCCCCHHHHHCCEEEEECCCCHHHHHHH
KERFLQFRSGAFSDKKSYFHHYSSLTDDEANTIAANIWDTINGPNLQLNIQPTRERAHLI
HHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHEEHHHHHCCCCCCEEEEECCCHHHHHHH
LQKGQDHLMSHVLMRK
HHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA