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The map label for this gene is cph2 [H]

Identifier: 126176222

GI number: 126176222

Start: 4738816

End: 4740648

Strand: Reverse

Name: cph2 [H]

Synonym: Sbal_4036

Alternate gene names: 126176222

Gene position: 4740648-4738816 (Counterclockwise)

Preceding gene: 126176223

Following gene: 126176220

Centisome position: 92.46

GC content: 46.54

Gene sequence:

>1833_bases
ATGAAGCATCGAAATCATTCTATTAGTCATAAGATGACGCTGACCATTATCGGGGTGAGCTCATTTTTTGCTGTGTTAAC
TATGCTGGTGCAGCTGATTTGGAACTATCAGGATAGTATCGACAATGCCACGTCGGATATCCGCGAATATTCAGAATCTA
TTCTGCCGAGTGTGGCGAAGTCGCTGTGGGACGTTGACCGCAGCCTGCTATCTGATTTGCTCTCTGGTTTAGGAATGATG
CCGTTAGTGTCGAGCGTGCATTTAGACAGTATCGACGGTGTCACTATGCAGCTGGGTAAACCGCTGTTAACCGACGACGA
GTCGCAAACCCTGTTTCATTATCCTGTGACTTATCAAGATCAGCTGATCGCAACTTTAACCGTAGGCTTAGACACTAACC
AGCTTTACTACGAGCTGTGGCGACAGTTGATTTTTATTGTGCTCGGCAATGGCTTAAAGACCCTGCTGATGATCTATTTG
ATCTTGACCTTAGTGCGACTCATGGTGACGGATAGATTGTCGGCATTGGAAGATTTTACTAATAAAATCAATCTAAAATC
GCTAAAAAAGCTATCTGTGCCCGAGACGGTGACCGCCAGTCCTGACGAGATTGCCCATGTGGCATTGTCGCTTAAGGCCA
TGTATCAAAGGATACGCAACGACCTCGCTATCAATAAACGCCATCAACGTGCGTTACAGCAACAGCAGCATTTATTGTCG
GACTTAGTGAAAGAGCGGACCAAAGAACTGGATTGGCAGTCGCAGTCGAATCAATTACTGGCAGAGATTTCGCTGCAATT
TTTGAGTATCGACACCTGCAATGTAGACAAAACCTTAACTGAGGTGTGCCACAAAATAGGTCAGTTGTTTGATGTTGAAA
GGGTGAGTATTCTCGAATTTCATCAACAGCATGCCTATTACCGCAGTTTTTGGACCAGCGAGTTACATGCTAACAAGGTC
CAAGGGATTTCGGTGGACAACATTACTCAGCTTGCTAAAAAATTCGAAACAGAATCGACTTTAGTGATTGAGGATCTTGA
GGCGTTAAAGGACTTTTCACCACAGGAATATGAGGTGATGAAATCCGTGGGCATTTGCTCTATTGCTGCCTTTGCGATTA
AAAATGCCGGAGAGTTATTGGGATTACTCTCGCTGTCGACGGTGTCGCGGCCCTTGAATTGGAACGCCCAGAAAAAAAAT
ATGCTGACTCAGTTTGCCTCCGCATTGAACGAGTTACTGCTGCGCGAGCAAAAAGAGCGGCAGATGATAGTGCTGCAACA
AGCGCTGGTTTCTGCCAATACTCAATTGAAAGAAATGGCCGAAACCGATGAGTTAACGGGCTTAGCCAATAGACGCCCCT
TTACCGAAAGATTAGAAACCGTACTACAGGCGGATACTCCTGCGGGACTGTTTATGTTGGACGTCGATTATTTCAAATCC
TACAACGACACTTACGTTCATCTCGAAGGTGATGTCGTGCTTAAGCGTGTGGCAGATGCCTTAGCGCAGTGCGATATTTT
GCCGCACAATGCTTTGTTAGCGCGCATCGGGGGCGAAGAGTTTGCCTTAGTCGTTGAGCACGTCACGCCGGCACAGTTAA
CGGCTATTGCCACGCAGTTGTGTTATCTCGTCGAGCAACTCAATATTCCCCATCAAGCTTCTCCCTTGGCTGTGTTGACC
ATCAGTATTGGCTGCGTGTTTTTGCCATTAGATAAGGTTTCGGGGCTTAAGATGGCCGACGTGTTACGCCGCGCCGATGT
TTGCCTCTATCGCGCTAAGGATAAAGGTCGCAATAGAGTTGAGGTTGAGGCATGTAATACAAGGACGTATTGA

Upstream 100 bases:

>100_bases
TTCGGCATTTTATCAAATGTTAGTTGCTCGGGATTGGCCACAGATTTTCCAGTCTCAGATTTTGAATAAGTTGCCCTTCA
AGGCGTAATAACGGGTGTAC

Downstream 100 bases:

>100_bases
GTAAGTTTTTTCTAGCTTACTAAATGGGCCGCTAAGTTTAGGAGTTAAACCGTTATGAGAAGCGACTAACCACAAGATCA
GAGTCAAGAGCTTATAAGCT

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 610; Mature: 610

Protein sequence:

>610_residues
MKHRNHSISHKMTLTIIGVSSFFAVLTMLVQLIWNYQDSIDNATSDIREYSESILPSVAKSLWDVDRSLLSDLLSGLGMM
PLVSSVHLDSIDGVTMQLGKPLLTDDESQTLFHYPVTYQDQLIATLTVGLDTNQLYYELWRQLIFIVLGNGLKTLLMIYL
ILTLVRLMVTDRLSALEDFTNKINLKSLKKLSVPETVTASPDEIAHVALSLKAMYQRIRNDLAINKRHQRALQQQQHLLS
DLVKERTKELDWQSQSNQLLAEISLQFLSIDTCNVDKTLTEVCHKIGQLFDVERVSILEFHQQHAYYRSFWTSELHANKV
QGISVDNITQLAKKFETESTLVIEDLEALKDFSPQEYEVMKSVGICSIAAFAIKNAGELLGLLSLSTVSRPLNWNAQKKN
MLTQFASALNELLLREQKERQMIVLQQALVSANTQLKEMAETDELTGLANRRPFTERLETVLQADTPAGLFMLDVDYFKS
YNDTYVHLEGDVVLKRVADALAQCDILPHNALLARIGGEEFALVVEHVTPAQLTAIATQLCYLVEQLNIPHQASPLAVLT
ISIGCVFLPLDKVSGLKMADVLRRADVCLYRAKDKGRNRVEVEACNTRTY

Sequences:

>Translated_610_residues
MKHRNHSISHKMTLTIIGVSSFFAVLTMLVQLIWNYQDSIDNATSDIREYSESILPSVAKSLWDVDRSLLSDLLSGLGMM
PLVSSVHLDSIDGVTMQLGKPLLTDDESQTLFHYPVTYQDQLIATLTVGLDTNQLYYELWRQLIFIVLGNGLKTLLMIYL
ILTLVRLMVTDRLSALEDFTNKINLKSLKKLSVPETVTASPDEIAHVALSLKAMYQRIRNDLAINKRHQRALQQQQHLLS
DLVKERTKELDWQSQSNQLLAEISLQFLSIDTCNVDKTLTEVCHKIGQLFDVERVSILEFHQQHAYYRSFWTSELHANKV
QGISVDNITQLAKKFETESTLVIEDLEALKDFSPQEYEVMKSVGICSIAAFAIKNAGELLGLLSLSTVSRPLNWNAQKKN
MLTQFASALNELLLREQKERQMIVLQQALVSANTQLKEMAETDELTGLANRRPFTERLETVLQADTPAGLFMLDVDYFKS
YNDTYVHLEGDVVLKRVADALAQCDILPHNALLARIGGEEFALVVEHVTPAQLTAIATQLCYLVEQLNIPHQASPLAVLT
ISIGCVFLPLDKVSGLKMADVLRRADVCLYRAKDKGRNRVEVEACNTRTY
>Mature_610_residues
MKHRNHSISHKMTLTIIGVSSFFAVLTMLVQLIWNYQDSIDNATSDIREYSESILPSVAKSLWDVDRSLLSDLLSGLGMM
PLVSSVHLDSIDGVTMQLGKPLLTDDESQTLFHYPVTYQDQLIATLTVGLDTNQLYYELWRQLIFIVLGNGLKTLLMIYL
ILTLVRLMVTDRLSALEDFTNKINLKSLKKLSVPETVTASPDEIAHVALSLKAMYQRIRNDLAINKRHQRALQQQQHLLS
DLVKERTKELDWQSQSNQLLAEISLQFLSIDTCNVDKTLTEVCHKIGQLFDVERVSILEFHQQHAYYRSFWTSELHANKV
QGISVDNITQLAKKFETESTLVIEDLEALKDFSPQEYEVMKSVGICSIAAFAIKNAGELLGLLSLSTVSRPLNWNAQKKN
MLTQFASALNELLLREQKERQMIVLQQALVSANTQLKEMAETDELTGLANRRPFTERLETVLQADTPAGLFMLDVDYFKS
YNDTYVHLEGDVVLKRVADALAQCDILPHNALLARIGGEEFALVVEHVTPAQLTAIATQLCYLVEQLNIPHQASPLAVLT
ISIGCVFLPLDKVSGLKMADVLRRADVCLYRAKDKGRNRVEVEACNTRTY

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI1787262, Length=187, Percent_Identity=36.8983957219251, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787541, Length=171, Percent_Identity=33.3333333333333, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787816, Length=162, Percent_Identity=35.8024691358025, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788956, Length=199, Percent_Identity=35.1758793969849, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787802, Length=185, Percent_Identity=34.5945945945946, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1786584, Length=182, Percent_Identity=36.2637362637363, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87081881, Length=170, Percent_Identity=34.1176470588235, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI145693134, Length=164, Percent_Identity=31.0975609756098, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788381, Length=177, Percent_Identity=30.5084745762712, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 68824; Mature: 68824

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHRNHSISHKMTLTIIGVSSFFAVLTMLVQLIWNYQDSIDNATSDIREYSESILPSVAK
CCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLWDVDRSLLSDLLSGLGMMPLVSSVHLDSIDGVTMQLGKPLLTDDESQTLFHYPVTYQD
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCEEEECCCCCCC
QLIATLTVGLDTNQLYYELWRQLIFIVLGNGLKTLLMIYLILTLVRLMVTDRLSALEDFT
CEEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NKINLKSLKKLSVPETVTASPDEIAHVALSLKAMYQRIRNDLAINKRHQRALQQQQHLLS
HCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
DLVKERTKELDWQSQSNQLLAEISLQFLSIDTCNVDKTLTEVCHKIGQLFDVERVSILEF
HHHHHHHHHCCCCCHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHH
HQQHAYYRSFWTSELHANKVQGISVDNITQLAKKFETESTLVIEDLEALKDFSPQEYEVM
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHH
KSVGICSIAAFAIKNAGELLGLLSLSTVSRPLNWNAQKKNMLTQFASALNELLLREQKER
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QMIVLQQALVSANTQLKEMAETDELTGLANRRPFTERLETVLQADTPAGLFMLDVDYFKS
HHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEHHHHHC
YNDTYVHLEGDVVLKRVADALAQCDILPHNALLARIGGEEFALVVEHVTPAQLTAIATQL
CCCCEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEEECCCHHHHHHHHHHH
CYLVEQLNIPHQASPLAVLTISIGCVFLPLDKVSGLKMADVLRRADVCLYRAKDKGRNRV
HHHHHHCCCCCCCCCCEEEEEECCEEEEEHHHCCCCHHHHHHHHHHHHEEECCCCCCCEE
EVEACNTRTY
EEEECCCCCC
>Mature Secondary Structure
MKHRNHSISHKMTLTIIGVSSFFAVLTMLVQLIWNYQDSIDNATSDIREYSESILPSVAK
CCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLWDVDRSLLSDLLSGLGMMPLVSSVHLDSIDGVTMQLGKPLLTDDESQTLFHYPVTYQD
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCEEEECCCCCCC
QLIATLTVGLDTNQLYYELWRQLIFIVLGNGLKTLLMIYLILTLVRLMVTDRLSALEDFT
CEEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NKINLKSLKKLSVPETVTASPDEIAHVALSLKAMYQRIRNDLAINKRHQRALQQQQHLLS
HCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
DLVKERTKELDWQSQSNQLLAEISLQFLSIDTCNVDKTLTEVCHKIGQLFDVERVSILEF
HHHHHHHHHCCCCCHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHH
HQQHAYYRSFWTSELHANKVQGISVDNITQLAKKFETESTLVIEDLEALKDFSPQEYEVM
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHH
KSVGICSIAAFAIKNAGELLGLLSLSTVSRPLNWNAQKKNMLTQFASALNELLLREQKER
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QMIVLQQALVSANTQLKEMAETDELTGLANRRPFTERLETVLQADTPAGLFMLDVDYFKS
HHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEHHHHHC
YNDTYVHLEGDVVLKRVADALAQCDILPHNALLARIGGEEFALVVEHVTPAQLTAIATQL
CCCCEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEEECCCHHHHHHHHHHH
CYLVEQLNIPHQASPLAVLTISIGCVFLPLDKVSGLKMADVLRRADVCLYRAKDKGRNRV
HHHHHHCCCCCCCCCCEEEEEECCEEEEEHHHCCCCHHHHHHHHHHHHEEECCCCCCCEE
EVEACNTRTY
EEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]