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The map label for this gene is hemY [H]

Identifier: 126176190

GI number: 126176190

Start: 4691323

End: 4692489

Strand: Direct

Name: hemY [H]

Synonym: Sbal_4003

Alternate gene names: 126176190

Gene position: 4691323-4692489 (Clockwise)

Preceding gene: 126176189

Following gene: 126176191

Centisome position: 91.5

GC content: 47.81

Gene sequence:

>1167_bases
ATGATCAAAATATTAATTTTCTTAGGGATTGTGCTAATAGGGCTCTGTATCAGCCCTTGGTTGGTTGGTAATACAGGTTA
TGTCTATATCGCTGCGGGTGACTACCAGATTGAGACCAGCTTAGTCTTTGGGATCATTGCGTTAATTGTATTTTATGCCG
TATTCCAAGTACTCGAATGGCTAGTGATTAGCGCCATCAATCTGATGCTGCGCAGTCGTTTTATTCCCCATCACTGGCGC
CGCCGCTCGGCTAAAAAACATACCTTAATGGGTGCACTGGCTCTGGCTGAAGAAGATTGGCCAGCAGCGGAACGCGCCAT
GATAAAGGGCGCTGACAACGGCGAGCTCCCTGCACTTAATTTACTTGCTGCGGCCCGTGCCGCTCAGTATCAACAAAAAA
TAGCCGAACGAGATCAATATCTTGATCGCGCTGCAGCGCAACCTCTTGCCGCGAATGCCGTCGCAACCACTCGCACTCGA
TACCTCTTAAAACAAGGGAAATTAGCCCTAGCCCGCGCCGAACTGGATAAATTAGCACCGACGAGCAAGAGTAAAGCGCC
ACTACTCAAACTCGCCCTTGAGTTATACCGAACCCAAGAGGATTGGGATGCACTCAAGCTGTTAATACCTATTTTGAAGA
AGCGTCAGATCCTCGATGATGCTCAGCTGAATGAGCTCAATATCGCCACAAATTGCGCGTTACTCAAAGGCGCAGCCATC
AAAGGTGAAGAAGCTTTAGAACAATGCTGGCAATGGTTATCTCGCAGTGAACGCAATCAGTCTGAGTTTCTGGCGATTTA
TGCCATGGGTTTATGCCGCTTTAATCGCAAAGACCAAGCGCTGAAACTAATCGCGAAAAAGTTACGAACCTCTCCCGAGT
CAGCACTTTTACATGCAATTCCTGAAATCGCGACAGCCCAAGACACAGAGATCCGTAAACAGTTACTCAAGCATGAAGTC
ACCCATGAGAATAATGCGGACTACCAGATGTGTTTAGCTAAGCTGTATCAGCAAACGCGGGATATGAAAGAAGCCAGAAG
CTGCTTGCAGAATGTTTGCCGACTCGAACCAACAAAAAACTCATGGCTGGCGCTCGCTCGCATTCAAGAACAGTTAGGCG
AACAAGGTCACGCCAATCAAAGCTACCGTCAGACAGTTAACCTGTAG

Upstream 100 bases:

>100_bases
TAGAACTTGATCCTATTACCCTGAAATCTTTTGCAGCTAAACCTCTGTTATTACAGCTGACTAGTTATGGCGAGCTGACC
TCATCAGAGGATGCGCCACT

Downstream 100 bases:

>100_bases
CTCTACTACATCAATAATGATAACGCCGTGATTCGCACTGTTGTGAGTCACGGCGTTTACCACTCACGAAAGTTCTTGCT
TCGTTTCTACTCAAAAACGT

Product: HemY domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MIKILIFLGIVLIGLCISPWLVGNTGYVYIAAGDYQIETSLVFGIIALIVFYAVFQVLEWLVISAINLMLRSRFIPHHWR
RRSAKKHTLMGALALAEEDWPAAERAMIKGADNGELPALNLLAAARAAQYQQKIAERDQYLDRAAAQPLAANAVATTRTR
YLLKQGKLALARAELDKLAPTSKSKAPLLKLALELYRTQEDWDALKLLIPILKKRQILDDAQLNELNIATNCALLKGAAI
KGEEALEQCWQWLSRSERNQSEFLAIYAMGLCRFNRKDQALKLIAKKLRTSPESALLHAIPEIATAQDTEIRKQLLKHEV
THENNADYQMCLAKLYQQTRDMKEARSCLQNVCRLEPTKNSWLALARIQEQLGEQGHANQSYRQTVNL

Sequences:

>Translated_388_residues
MIKILIFLGIVLIGLCISPWLVGNTGYVYIAAGDYQIETSLVFGIIALIVFYAVFQVLEWLVISAINLMLRSRFIPHHWR
RRSAKKHTLMGALALAEEDWPAAERAMIKGADNGELPALNLLAAARAAQYQQKIAERDQYLDRAAAQPLAANAVATTRTR
YLLKQGKLALARAELDKLAPTSKSKAPLLKLALELYRTQEDWDALKLLIPILKKRQILDDAQLNELNIATNCALLKGAAI
KGEEALEQCWQWLSRSERNQSEFLAIYAMGLCRFNRKDQALKLIAKKLRTSPESALLHAIPEIATAQDTEIRKQLLKHEV
THENNADYQMCLAKLYQQTRDMKEARSCLQNVCRLEPTKNSWLALARIQEQLGEQGHANQSYRQTVNL
>Mature_388_residues
MIKILIFLGIVLIGLCISPWLVGNTGYVYIAAGDYQIETSLVFGIIALIVFYAVFQVLEWLVISAINLMLRSRFIPHHWR
RRSAKKHTLMGALALAEEDWPAAERAMIKGADNGELPALNLLAAARAAQYQQKIAERDQYLDRAAAQPLAANAVATTRTR
YLLKQGKLALARAELDKLAPTSKSKAPLLKLALELYRTQEDWDALKLLIPILKKRQILDDAQLNELNIATNCALLKGAAI
KGEEALEQCWQWLSRSERNQSEFLAIYAMGLCRFNRKDQALKLIAKKLRTSPESALLHAIPEIATAQDTEIRKQLLKHEV
THENNADYQMCLAKLYQQTRDMKEARSCLQNVCRLEPTKNSWLALARIQEQLGEQGHANQSYRQTVNL

Specific function: Involved in a late step of protoheme IX synthesis [H]

COG id: COG3071

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1790234, Length=310, Percent_Identity=32.258064516129, Blast_Score=123, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010817
- InterPro:   IPR005254
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR013105
- InterPro:   IPR019734 [H]

Pfam domain/function: PF07219 HemY_N; PF07719 TPR_2 [H]

EC number: NA

Molecular weight: Translated: 43810; Mature: 43810

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKILIFLGIVLIGLCISPWLVGNTGYVYIAAGDYQIETSLVFGIIALIVFYAVFQVLEW
CHHHHHHHHHHHHHHHHCCCEECCCCEEEEEECCEEHHHHHHHHHHHHHHHHHHHHHHHH
LVISAINLMLRSRFIPHHWRRRSAKKHTLMGALALAEEDWPAAERAMIKGADNGELPALN
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHH
LLAAARAAQYQQKIAERDQYLDRAAAQPLAANAVATTRTRYLLKQGKLALARAELDKLAP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
TSKSKAPLLKLALELYRTQEDWDALKLLIPILKKRQILDDAQLNELNIATNCALLKGAAI
CCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCC
KGEEALEQCWQWLSRSERNQSEFLAIYAMGLCRFNRKDQALKLIAKKLRTSPESALLHAI
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHH
PEIATAQDTEIRKQLLKHEVTHENNADYQMCLAKLYQQTRDMKEARSCLQNVCRLEPTKN
HHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SWLALARIQEQLGEQGHANQSYRQTVNL
HHHHHHHHHHHHCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MIKILIFLGIVLIGLCISPWLVGNTGYVYIAAGDYQIETSLVFGIIALIVFYAVFQVLEW
CHHHHHHHHHHHHHHHHCCCEECCCCEEEEEECCEEHHHHHHHHHHHHHHHHHHHHHHHH
LVISAINLMLRSRFIPHHWRRRSAKKHTLMGALALAEEDWPAAERAMIKGADNGELPALN
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHH
LLAAARAAQYQQKIAERDQYLDRAAAQPLAANAVATTRTRYLLKQGKLALARAELDKLAP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
TSKSKAPLLKLALELYRTQEDWDALKLLIPILKKRQILDDAQLNELNIATNCALLKGAAI
CCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCC
KGEEALEQCWQWLSRSERNQSEFLAIYAMGLCRFNRKDQALKLIAKKLRTSPESALLHAI
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHH
PEIATAQDTEIRKQLLKHEVTHENNADYQMCLAKLYQQTRDMKEARSCLQNVCRLEPTKN
HHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SWLALARIQEQLGEQGHANQSYRQTVNL
HHHHHHHHHHHHCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]