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The map label for this gene is hemX [H]

Identifier: 126176189

GI number: 126176189

Start: 4690145

End: 4691326

Strand: Direct

Name: hemX [H]

Synonym: Sbal_4002

Alternate gene names: 126176189

Gene position: 4690145-4691326 (Clockwise)

Preceding gene: 126176188

Following gene: 126176190

Centisome position: 91.47

GC content: 48.73

Gene sequence:

>1182_bases
ATGGATAACAACAAGCACGACGCAAAGAGCCCAGAATCAGAGGCTACCGCTATTATTGTGTCACCGGAAACAACCGATGA
CATGTCCGCAACATCAGCGTCATCCACCGAATCCCAAACAGCCAAAGCCACACCTTCAACCGCGCCGAGCCAAACGCCAG
CATCCAATAGAAGCTCGTGGGCGATTCGCTTTGGGGTTTTATTAGCGCTGGGTTTAACCGCTTGCACCCTTGGCGGCGGT
TTTATGCTGTACCAACAAATGCAACAGCAACTGCTGGCGCAGGATGCGAAAAATATCGCCCTGCAGGACCAATTACAGCA
AGCGCTGTTGCAGCCAAATCAACGTATTGGCCAGCTTGAACAGCAACAACTGAATGATGCTAAGACTTATCAAGAATTAA
CAAAATTGGCAGAAGACCAAAATCAACTGCAGGACAGGGTCAATAAACTGGCCCAGCGCAGCCCAACGCATTGGATGGCC
TCTGAAGCCGAATATCTCGTGAATATGGCGGGCCGTAAACTTTGGTTAGAGAAAGATCCCCGCACCGCCACCGATCTATT
AAAGTCGGCGGATGAAACCATCGCCGCCATGAACAATCCGGCGTTACTGCCTATTCGTAAGGCATTAGCAAAAGACATCG
CCGCCACAGCCAGCATTAAAACCACAGATATTGATGGCAATGTATTGGCGCTCGATGCCTTAATTGAACAACTCGATAAA
CTGCCGCTGAATCGCACCGACGCAGAAGCCGATGTGCCAGAAGATACAACTATTACTGGGGATTTGAATGATTGGCAGAG
CAATCTGGGTAAAACGTGGAAAGCGTTAACCCAAGACTTTATTACCATACGCCACAAAACCGCCGATGCGCCCGCTTTAC
TCGCACCGGAACAGCAATGGTATCTGGTGGAGAACATTCGCCATAAGCTGCTGCAATCGCAACTTGCGTTATATCGCTAT
GACAGAGCGGCTTATCACCAATCATTGATGATGGCGCGCAAGTGGATCCAAACCTATTTTGATACGCAAGATCACAAGAC
AGCTGAGGCCATCGCCGAAATCGATAAATTAGCAACCTTAGAACTTGATCCTATTACCCTGAAATCTTTTGCAGCTAAAC
CTCTGTTATTACAGCTGACTAGTTATGGCGAGCTGACCTCATCAGAGGATGCGCCACTATGA

Upstream 100 bases:

>100_bases
CGCCAACAGCAAAGCCGTGCTAAACGCCCTTAAACTCTAAGCGCTATTTAGCCCGATTTTACTCGAATTTCGGCAGTAGC
ATGTTTTCAAGGACTGTTAA

Downstream 100 bases:

>100_bases
TCAAAATATTAATTTTCTTAGGGATTGTGCTAATAGGGCTCTGTATCAGCCCTTGGTTGGTTGGTAATACAGGTTATGTC
TATATCGCTGCGGGTGACTA

Product: hypothetical protein

Products: NA

Alternate protein names: Urogen-III methylase; ORF X [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MDNNKHDAKSPESEATAIIVSPETTDDMSATSASSTESQTAKATPSTAPSQTPASNRSSWAIRFGVLLALGLTACTLGGG
FMLYQQMQQQLLAQDAKNIALQDQLQQALLQPNQRIGQLEQQQLNDAKTYQELTKLAEDQNQLQDRVNKLAQRSPTHWMA
SEAEYLVNMAGRKLWLEKDPRTATDLLKSADETIAAMNNPALLPIRKALAKDIAATASIKTTDIDGNVLALDALIEQLDK
LPLNRTDAEADVPEDTTITGDLNDWQSNLGKTWKALTQDFITIRHKTADAPALLAPEQQWYLVENIRHKLLQSQLALYRY
DRAAYHQSLMMARKWIQTYFDTQDHKTAEAIAEIDKLATLELDPITLKSFAAKPLLLQLTSYGELTSSEDAPL

Sequences:

>Translated_393_residues
MDNNKHDAKSPESEATAIIVSPETTDDMSATSASSTESQTAKATPSTAPSQTPASNRSSWAIRFGVLLALGLTACTLGGG
FMLYQQMQQQLLAQDAKNIALQDQLQQALLQPNQRIGQLEQQQLNDAKTYQELTKLAEDQNQLQDRVNKLAQRSPTHWMA
SEAEYLVNMAGRKLWLEKDPRTATDLLKSADETIAAMNNPALLPIRKALAKDIAATASIKTTDIDGNVLALDALIEQLDK
LPLNRTDAEADVPEDTTITGDLNDWQSNLGKTWKALTQDFITIRHKTADAPALLAPEQQWYLVENIRHKLLQSQLALYRY
DRAAYHQSLMMARKWIQTYFDTQDHKTAEAIAEIDKLATLELDPITLKSFAAKPLLLQLTSYGELTSSEDAPL
>Mature_393_residues
MDNNKHDAKSPESEATAIIVSPETTDDMSATSASSTESQTAKATPSTAPSQTPASNRSSWAIRFGVLLALGLTACTLGGG
FMLYQQMQQQLLAQDAKNIALQDQLQQALLQPNQRIGQLEQQQLNDAKTYQELTKLAEDQNQLQDRVNKLAQRSPTHWMA
SEAEYLVNMAGRKLWLEKDPRTATDLLKSADETIAAMNNPALLPIRKALAKDIAATASIKTTDIDGNVLALDALIEQLDK
LPLNRTDAEADVPEDTTITGDLNDWQSNLGKTWKALTQDFITIRHKTADAPALLAPEQQWYLVENIRHKLLQSQLALYRY
DRAAYHQSLMMARKWIQTYFDTQDHKTAEAIAEIDKLATLELDPITLKSFAAKPLLLQLTSYGELTSSEDAPL

Specific function: Siroheme and cobalamin biosynthesis. [C]

COG id: COG2959

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790235, Length=309, Percent_Identity=36.5695792880259, Blast_Score=167, Evalue=2e-42,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007470 [H]

Pfam domain/function: PF04375 HemX [H]

EC number: =2.1.1.107 [H]

Molecular weight: Translated: 43558; Mature: 43558

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNNKHDAKSPESEATAIIVSPETTDDMSATSASSTESQTAKATPSTAPSQTPASNRSSW
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCH
AIRFGVLLALGLTACTLGGGFMLYQQMQQQLLAQDAKNIALQDQLQQALLQPNQRIGQLE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
QQQLNDAKTYQELTKLAEDQNQLQDRVNKLAQRSPTHWMASEAEYLVNMAGRKLWLEKDP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEECCCC
RTATDLLKSADETIAAMNNPALLPIRKALAKDIAATASIKTTDIDGNVLALDALIEQLDK
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHC
LPLNRTDAEADVPEDTTITGDLNDWQSNLGKTWKALTQDFITIRHKTADAPALLAPEQQW
CCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCHHH
YLVENIRHKLLQSQLALYRYDRAAYHQSLMMARKWIQTYFDTQDHKTAEAIAEIDKLATL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHC
ELDPITLKSFAAKPLLLQLTSYGELTSSEDAPL
CCCCCHHHHHCCCCHHEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MDNNKHDAKSPESEATAIIVSPETTDDMSATSASSTESQTAKATPSTAPSQTPASNRSSW
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCH
AIRFGVLLALGLTACTLGGGFMLYQQMQQQLLAQDAKNIALQDQLQQALLQPNQRIGQLE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
QQQLNDAKTYQELTKLAEDQNQLQDRVNKLAQRSPTHWMASEAEYLVNMAGRKLWLEKDP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEECCCC
RTATDLLKSADETIAAMNNPALLPIRKALAKDIAATASIKTTDIDGNVLALDALIEQLDK
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHC
LPLNRTDAEADVPEDTTITGDLNDWQSNLGKTWKALTQDFITIRHKTADAPALLAPEQQW
CCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCHHH
YLVENIRHKLLQSQLALYRYDRAAYHQSLMMARKWIQTYFDTQDHKTAEAIAEIDKLATL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHC
ELDPITLKSFAAKPLLLQLTSYGELTSSEDAPL
CCCCCHHHHHCCCCHHEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3062586; 3054815; 1379743; 9278503; 9298646 [H]