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The map label for this gene is coaE [H]

Identifier: 126176112

GI number: 126176112

Start: 4617530

End: 4618147

Strand: Direct

Name: coaE [H]

Synonym: Sbal_3922

Alternate gene names: 126176112

Gene position: 4617530-4618147 (Clockwise)

Preceding gene: 126176111

Following gene: 126176113

Centisome position: 90.06

GC content: 46.6

Gene sequence:

>618_bases
ATGTCAAAGTTTGTCGTTGGCCTTACAGGCGGCATCGGCAGCGGTAAAACGACTGTTGCCAATTTGTTCGCCGCCGAAGG
GGTTGCCTTAGTCGACGCAGATATCGTTGCCCGCGAAGTTGTCGCTCCGGGTTCAAAAGGACTGGAAGCGATCGTAACTC
ATTTTGGTGCTGAGATATTAACACCAGAGGGTGAACTCGATCGCGCCAAGTTGCGGCAGCGGATATTTAGCCATCCTAAA
GAGCGCGAATGGCTAAACCAACTATTACACCCCATGATCCGCCAAGAAATGCTAGCGCAGGTAGAAAAAGCGACCTCTGC
CTATGTAATTATGGTCGTGCCCTTGCTATTTGAGAACGGGTTAGATAGGTTAGTCAATCGGACTTTAGTGGTAGATATTT
CGCCTGAGTTGCAAATAAATCGCACCGTAAAACGTGACAATGTTGATGCATCTCAAGTTAATAACATCATTAGTAGTCAA
TGTAGTCGCAGCGAAAAACTCGCCAGAGCCGACGACATTATTGATAATCAAGGAGAGATATCAACCTTAAAACGAGAGGT
GCTAGCATTGCACCAGCGATATTTACAACTTTCTGGTACTGATAACGCCCATGACTGA

Upstream 100 bases:

>100_bases
TGGCTGGATAGCCTTGCTATTTGGGCAACAGATTGTCGATTGGTACCTATCGACACTGTAAGATCTAGCAAATTAAGCAC
AAAGCTATCCGGAGTATGTT

Downstream 100 bases:

>100_bases
ATTAGTTTACGAACAGCCCCTAAACGAGAAAATTCGCAGCTACTTGCGGCTCGAATACCTCGATAAACAGCTGCAAAGTA
ACCTAAGTCATGACCACCAA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MSKFVVGLTGGIGSGKTTVANLFAAEGVALVDADIVAREVVAPGSKGLEAIVTHFGAEILTPEGELDRAKLRQRIFSHPK
EREWLNQLLHPMIRQEMLAQVEKATSAYVIMVVPLLFENGLDRLVNRTLVVDISPELQINRTVKRDNVDASQVNNIISSQ
CSRSEKLARADDIIDNQGEISTLKREVLALHQRYLQLSGTDNAHD

Sequences:

>Translated_205_residues
MSKFVVGLTGGIGSGKTTVANLFAAEGVALVDADIVAREVVAPGSKGLEAIVTHFGAEILTPEGELDRAKLRQRIFSHPK
EREWLNQLLHPMIRQEMLAQVEKATSAYVIMVVPLLFENGLDRLVNRTLVVDISPELQINRTVKRDNVDASQVNNIISSQ
CSRSEKLARADDIIDNQGEISTLKREVLALHQRYLQLSGTDNAHD
>Mature_204_residues
SKFVVGLTGGIGSGKTTVANLFAAEGVALVDADIVAREVVAPGSKGLEAIVTHFGAEILTPEGELDRAKLRQRIFSHPKE
REWLNQLLHPMIRQEMLAQVEKATSAYVIMVVPLLFENGLDRLVNRTLVVDISPELQINRTVKRDNVDASQVNNIISSQC
SRSEKLARADDIIDNQGEISTLKREVLALHQRYLQLSGTDNAHD

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=192, Percent_Identity=38.5416666666667, Blast_Score=134, Evalue=5e-32,
Organism=Homo sapiens, GI191252795, Length=192, Percent_Identity=38.5416666666667, Blast_Score=134, Evalue=5e-32,
Organism=Homo sapiens, GI110227607, Length=188, Percent_Identity=27.6595744680851, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI110227605, Length=188, Percent_Identity=27.6595744680851, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI110227603, Length=188, Percent_Identity=27.6595744680851, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI110227601, Length=188, Percent_Identity=27.6595744680851, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI205277394, Length=188, Percent_Identity=27.6595744680851, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1786292, Length=197, Percent_Identity=52.2842639593909, Blast_Score=213, Evalue=9e-57,
Organism=Caenorhabditis elegans, GI17554944, Length=188, Percent_Identity=40.9574468085106, Blast_Score=141, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI25143409, Length=165, Percent_Identity=29.6969696969697, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320402, Length=192, Percent_Identity=36.4583333333333, Blast_Score=110, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24644728, Length=192, Percent_Identity=31.7708333333333, Blast_Score=120, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24658602, Length=185, Percent_Identity=28.1081081081081, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977
- InterPro:   IPR000764 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22577; Mature: 22446

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKFVVGLTGGIGSGKTTVANLFAAEGVALVDADIVAREVVAPGSKGLEAIVTHFGAEIL
CCCEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHC
TPEGELDRAKLRQRIFSHPKEREWLNQLLHPMIRQEMLAQVEKATSAYVIMVVPLLFENG
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDRLVNRTLVVDISPELQINRTVKRDNVDASQVNNIISSQCSRSEKLARADDIIDNQGEI
HHHHHCCEEEEEECCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
STLKREVLALHQRYLQLSGTDNAHD
HHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SKFVVGLTGGIGSGKTTVANLFAAEGVALVDADIVAREVVAPGSKGLEAIVTHFGAEIL
CCEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHC
TPEGELDRAKLRQRIFSHPKEREWLNQLLHPMIRQEMLAQVEKATSAYVIMVVPLLFENG
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDRLVNRTLVVDISPELQINRTVKRDNVDASQVNNIISSQCSRSEKLARADDIIDNQGEI
HHHHHCCEEEEEECCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
STLKREVLALHQRYLQLSGTDNAHD
HHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]