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The map label for this gene is aceE [H]

Identifier: 126176103

GI number: 126176103

Start: 4605545

End: 4608211

Strand: Reverse

Name: aceE [H]

Synonym: Sbal_3913

Alternate gene names: 126176103

Gene position: 4608211-4605545 (Counterclockwise)

Preceding gene: 126176104

Following gene: 126176102

Centisome position: 89.87

GC content: 47.54

Gene sequence:

>2667_bases
ATGTCTGAAGATATGCTACAAGACGTAGATCCATTAGAGACTCAGGAATGGGTTGATGCCCTGCAAGCCGTGTTGGAACA
GGAAGGCCCAGAGCGCGCGCATTTTTTACTAGAGAAGCTGATCGATAAAGCGCGTCGTAATGGCACTCACTTGCCTTACA
ATGCCACAACGGCTTACTTGAACACTATCCCAGCGGGTCAAGAGCCTCACATGCCTGGCAACCAAGAGATGGAACGTCGC
ATTCGCGCCATCATCCGTTGGAACGCTTTGGCTATGGTTCTGCGTGGTTCTAAGAAAGATTTAGAGTTGGGCGGCCATAT
CTCAAGTTTCGCTTCAAGCGCGACTATCTATGACGTATGTTTTAACCACTTCTTCCGTGCACCGAATGAGAAAGACGGTG
GCGATCTCGTGTATTTCCAAGGCCATATCGCCCCTGGTATTTATGCGCGTTCTTTCCTAGAAGGTCGTTTAAGCGAAGAG
CAACTGGCTAACTTCCGTCAAGAAGTGGATGGCAAGGGTCTGTCTTCATACCCACATCCAAAATTGATGCCGGATTACTG
GCAATTCCCAACGGTTTCTATGGGCTTAGGTCCAATCCAAGCCATCTATCAAGCCCGTTTCCTGAAATATCTGACTGACC
GTGGTCTGAAAGATTGTTCAGCACAAACTGTTTACTGTTTCTTAGGTGACGGTGAGTGTGACGAGCCAGAAGCCTTAGGC
GCTATCGGTTTAGCGGCCCGTGAAGAATTAGACAACTTAGTCTTCATCGTTAACTGTAACTTACAGCGTCTTGATGGCCC
TGTACGTGGTAACGGCAAGATCATCCAAGAACTTGAAGGCGAATTCCGCGGCGCAGGCTGGGAAGTTGTTAAAGTGATTT
GGGGTCGTTACTGGGATCCATTATTGGCCCGTGACACCAGCGGTAAACTACTGCAGTTAATGGAAGAAACCGTTGACGGT
GAATACCAAAACTGTAAAGCCAAAGGTGGCGCTTATACACGCGAACACTTCTTTGGTAAGTATCCTGAAACGGCCGAAAT
GGTTGCTAACATGTCAGATGATGACATTTGGCGCTTAAACCGCGGCGGTCATGATCCAGTTAAAGTTTACGCTGCACTGG
AACATGCACAAAAAACCAAAGGCCGTCCAACGGTTATCTTAGCTAAAACCGTTAAAGGTTACGGCTTAGGTGATGCGGGT
GAAGGTAAAAACATCGCGCACAACGTGAAGAAGATGGGCGTTGAGTCTATCCGTTACTTCCGCGATCGTTTCAATATCCC
GATCCCAGATGACCAGTTAGAAGATCTGCCTTTCTATCACCCAGGTCCAGATTCTGAAGAAGTGAAGTACATGATGAGCC
GTCGTGAAGCGCTGCATGGTAGCGTGCCACAACGTCGTCAAAAGTTCACTGAAGAGATGGAAGTGCCGTCACTGAAGATT
TTCGATTCGATTTTACAGGGCTCAAACGGCCGTGAAATTTCATCGACTATGGCGTTCGTTCGCGTGCTGACAGCATTGCT
GAAAGACAAGAAAATTGGCAAAAACATTGTGCCAATTATTCCTGACGAAGCCCGTACTTTCGGTATGGAAGGTCTGTTCC
GTCAAGTGGGTATTTATGCTCACGAAGGCCAAAAATACGTACCGCAAGACTCTGACCAAGTGGCTTATTATCGTGAAGAT
AAAACCGGTCAAGTATTGCAAGAAGGGATTAACGAACTAGGTGCCATGTCTTCATGGGTATCGGCAGCGACGAGCTACTC
AGTCAACGATACACCTATGATCCCGTTCTACATCTACTACTCAATGTTCGGTTTCCAACGTATTGGCGACATGGCTTGGG
CAGCGGGTGATATGCGTGCTCGTGGTTTCTTAGTCGGTGGTACTTCAGGTCGTACAACGCTTAACGGCGAAGGTTTACAG
CATCAAGATGGTCACAGCCACGTATTGGCGAACACTATCCCTAACTGTATTTCTTACGATCCAACCTACGGCTACGAAAT
TGCCGTTGTGGTACAAGATGGTATCCGTCGTATGTACGGCGAGAATCAAGAAGATATCTTCTACTACTTGACCACAATGA
ACGAAAACTATGAGCAACCAGCCATGCCAGAAGGCGCGGAAGTGGGCATAGTGAAAGGCATCTATAAGTTAGAAACGGTT
GCGGGCTCAGGTAAAGGCAAAGTTCAGTTAATGAGCTGTGGCACTATCCTTGAACAAACCCGTAAAGCGGCGCAAGCACT
GGCAAAAGACTTCGGTATTACTGCCGACGTATTTAGCGTAACTAGCTTCAACGAATTGACTCGCGATGGTCAAGCCGCTG
AACGTTGGAACATGCTGCACCCAACCGAAACGCCAAAACAAGCCTATATCAGCCAAGTGATTTCAAGTGATGCACCTGCA
ATCGTCGCGACTGACTATATGAAGATTTACGGCGAACAGTTACGTGCTTACATTCCTACCGATTACAAAGTGTTAGGTAC
TGACGGTTTCGGTCGTTCAGATAGCCGCGACAATCTGCGTCACCACTTTGAAGTGGACGCTAAGTTCATCGTTATTGCGG
CACTGAAATCACTGGTTGATCGCAAAGAGCTGCCTGTCGATGTGTTAGTAAAAGCCATTAAAGAATATGGTATCGACGCT
GACAAGATCAATCCACAGTACGCGTAA

Upstream 100 bases:

>100_bases
TTTAAAGAGTGGCGCTTAAGTTCTGTAGTTTAGCTGTCTGCTAAATCGGAATATGCCGCAAACACCATTCATTATCATGT
ATATAGAGAAGGACAGTGTC

Downstream 100 bases:

>100_bases
GAGGCAATAAAAATGGCTGAATTAAAAGAAGTTTTTGTTCCTGATATCGGCGGCGATGAAGTGCAAGTGATCGAAATTTG
TGTGGCTGTGGGTGATACCC

Product: pyruvate dehydrogenase subunit E1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 888; Mature: 887

Protein sequence:

>888_residues
MSEDMLQDVDPLETQEWVDALQAVLEQEGPERAHFLLEKLIDKARRNGTHLPYNATTAYLNTIPAGQEPHMPGNQEMERR
IRAIIRWNALAMVLRGSKKDLELGGHISSFASSATIYDVCFNHFFRAPNEKDGGDLVYFQGHIAPGIYARSFLEGRLSEE
QLANFRQEVDGKGLSSYPHPKLMPDYWQFPTVSMGLGPIQAIYQARFLKYLTDRGLKDCSAQTVYCFLGDGECDEPEALG
AIGLAAREELDNLVFIVNCNLQRLDGPVRGNGKIIQELEGEFRGAGWEVVKVIWGRYWDPLLARDTSGKLLQLMEETVDG
EYQNCKAKGGAYTREHFFGKYPETAEMVANMSDDDIWRLNRGGHDPVKVYAALEHAQKTKGRPTVILAKTVKGYGLGDAG
EGKNIAHNVKKMGVESIRYFRDRFNIPIPDDQLEDLPFYHPGPDSEEVKYMMSRREALHGSVPQRRQKFTEEMEVPSLKI
FDSILQGSNGREISSTMAFVRVLTALLKDKKIGKNIVPIIPDEARTFGMEGLFRQVGIYAHEGQKYVPQDSDQVAYYRED
KTGQVLQEGINELGAMSSWVSAATSYSVNDTPMIPFYIYYSMFGFQRIGDMAWAAGDMRARGFLVGGTSGRTTLNGEGLQ
HQDGHSHVLANTIPNCISYDPTYGYEIAVVVQDGIRRMYGENQEDIFYYLTTMNENYEQPAMPEGAEVGIVKGIYKLETV
AGSGKGKVQLMSCGTILEQTRKAAQALAKDFGITADVFSVTSFNELTRDGQAAERWNMLHPTETPKQAYISQVISSDAPA
IVATDYMKIYGEQLRAYIPTDYKVLGTDGFGRSDSRDNLRHHFEVDAKFIVIAALKSLVDRKELPVDVLVKAIKEYGIDA
DKINPQYA

Sequences:

>Translated_888_residues
MSEDMLQDVDPLETQEWVDALQAVLEQEGPERAHFLLEKLIDKARRNGTHLPYNATTAYLNTIPAGQEPHMPGNQEMERR
IRAIIRWNALAMVLRGSKKDLELGGHISSFASSATIYDVCFNHFFRAPNEKDGGDLVYFQGHIAPGIYARSFLEGRLSEE
QLANFRQEVDGKGLSSYPHPKLMPDYWQFPTVSMGLGPIQAIYQARFLKYLTDRGLKDCSAQTVYCFLGDGECDEPEALG
AIGLAAREELDNLVFIVNCNLQRLDGPVRGNGKIIQELEGEFRGAGWEVVKVIWGRYWDPLLARDTSGKLLQLMEETVDG
EYQNCKAKGGAYTREHFFGKYPETAEMVANMSDDDIWRLNRGGHDPVKVYAALEHAQKTKGRPTVILAKTVKGYGLGDAG
EGKNIAHNVKKMGVESIRYFRDRFNIPIPDDQLEDLPFYHPGPDSEEVKYMMSRREALHGSVPQRRQKFTEEMEVPSLKI
FDSILQGSNGREISSTMAFVRVLTALLKDKKIGKNIVPIIPDEARTFGMEGLFRQVGIYAHEGQKYVPQDSDQVAYYRED
KTGQVLQEGINELGAMSSWVSAATSYSVNDTPMIPFYIYYSMFGFQRIGDMAWAAGDMRARGFLVGGTSGRTTLNGEGLQ
HQDGHSHVLANTIPNCISYDPTYGYEIAVVVQDGIRRMYGENQEDIFYYLTTMNENYEQPAMPEGAEVGIVKGIYKLETV
AGSGKGKVQLMSCGTILEQTRKAAQALAKDFGITADVFSVTSFNELTRDGQAAERWNMLHPTETPKQAYISQVISSDAPA
IVATDYMKIYGEQLRAYIPTDYKVLGTDGFGRSDSRDNLRHHFEVDAKFIVIAALKSLVDRKELPVDVLVKAIKEYGIDA
DKINPQYA
>Mature_887_residues
SEDMLQDVDPLETQEWVDALQAVLEQEGPERAHFLLEKLIDKARRNGTHLPYNATTAYLNTIPAGQEPHMPGNQEMERRI
RAIIRWNALAMVLRGSKKDLELGGHISSFASSATIYDVCFNHFFRAPNEKDGGDLVYFQGHIAPGIYARSFLEGRLSEEQ
LANFRQEVDGKGLSSYPHPKLMPDYWQFPTVSMGLGPIQAIYQARFLKYLTDRGLKDCSAQTVYCFLGDGECDEPEALGA
IGLAAREELDNLVFIVNCNLQRLDGPVRGNGKIIQELEGEFRGAGWEVVKVIWGRYWDPLLARDTSGKLLQLMEETVDGE
YQNCKAKGGAYTREHFFGKYPETAEMVANMSDDDIWRLNRGGHDPVKVYAALEHAQKTKGRPTVILAKTVKGYGLGDAGE
GKNIAHNVKKMGVESIRYFRDRFNIPIPDDQLEDLPFYHPGPDSEEVKYMMSRREALHGSVPQRRQKFTEEMEVPSLKIF
DSILQGSNGREISSTMAFVRVLTALLKDKKIGKNIVPIIPDEARTFGMEGLFRQVGIYAHEGQKYVPQDSDQVAYYREDK
TGQVLQEGINELGAMSSWVSAATSYSVNDTPMIPFYIYYSMFGFQRIGDMAWAAGDMRARGFLVGGTSGRTTLNGEGLQH
QDGHSHVLANTIPNCISYDPTYGYEIAVVVQDGIRRMYGENQEDIFYYLTTMNENYEQPAMPEGAEVGIVKGIYKLETVA
GSGKGKVQLMSCGTILEQTRKAAQALAKDFGITADVFSVTSFNELTRDGQAAERWNMLHPTETPKQAYISQVISSDAPAI
VATDYMKIYGEQLRAYIPTDYKVLGTDGFGRSDSRDNLRHHFEVDAKFIVIAALKSLVDRKELPVDVLVKAIKEYGIDAD
KINPQYA

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=890, Percent_Identity=66.4044943820225, Blast_Score=1278, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=227, Percent_Identity=29.5154185022026, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 99465; Mature: 99334

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEDMLQDVDPLETQEWVDALQAVLEQEGPERAHFLLEKLIDKARRNGTHLPYNATTAYL
CCCHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
NTIPAGQEPHMPGNQEMERRIRAIIRWNALAMVLRGSKKDLELGGHISSFASSATIYDVC
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHHHHH
FNHFFRAPNEKDGGDLVYFQGHIAPGIYARSFLEGRLSEEQLANFRQEVDGKGLSSYPHP
HHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCC
KLMPDYWQFPTVSMGLGPIQAIYQARFLKYLTDRGLKDCSAQTVYCFLGDGECDEPEALG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHH
AIGLAAREELDNLVFIVNCNLQRLDGPVRGNGKIIQELEGEFRGAGWEVVKVIWGRYWDP
HHHHHHHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCH
LLARDTSGKLLQLMEETVDGEYQNCKAKGGAYTREHFFGKYPETAEMVANMSDDDIWRLN
HHHCCCCHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHCCCCCCHHHHHHCCCCCCEEECC
RGGHDPVKVYAALEHAQKTKGRPTVILAKTVKGYGLGDAGEGKNIAHNVKKMGVESIRYF
CCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RDRFNIPIPDDQLEDLPFYHPGPDSEEVKYMMSRREALHGSVPQRRQKFTEEMEVPSLKI
HHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHH
FDSILQGSNGREISSTMAFVRVLTALLKDKKIGKNIVPIIPDEARTFGMEGLFRQVGIYA
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCEEE
HEGQKYVPQDSDQVAYYREDKTGQVLQEGINELGAMSSWVSAATSYSVNDTPMIPFYIYY
ECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
SMFGFQRIGDMAWAAGDMRARGFLVGGTSGRTTLNGEGLQHQDGHSHVLANTIPNCISYD
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEECCCCCCCCCCCCEEHHHHCCHHHCCC
PTYGYEIAVVVQDGIRRMYGENQEDIFYYLTTMNENYEQPAMPEGAEVGIVKGIYKLETV
CCCCCEEEEEEHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHH
AGSGKGKVQLMSCGTILEQTRKAAQALAKDFGITADVFSVTSFNELTRDGQAAERWNMLH
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHCCCCC
PTETPKQAYISQVISSDAPAIVATDYMKIYGEQLRAYIPTDYKVLGTDGFGRSDSRDNLR
CCCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHH
HHFEVDAKFIVIAALKSLVDRKELPVDVLVKAIKEYGIDADKINPQYA
HHEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SEDMLQDVDPLETQEWVDALQAVLEQEGPERAHFLLEKLIDKARRNGTHLPYNATTAYL
CCHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
NTIPAGQEPHMPGNQEMERRIRAIIRWNALAMVLRGSKKDLELGGHISSFASSATIYDVC
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHHHHH
FNHFFRAPNEKDGGDLVYFQGHIAPGIYARSFLEGRLSEEQLANFRQEVDGKGLSSYPHP
HHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCC
KLMPDYWQFPTVSMGLGPIQAIYQARFLKYLTDRGLKDCSAQTVYCFLGDGECDEPEALG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHH
AIGLAAREELDNLVFIVNCNLQRLDGPVRGNGKIIQELEGEFRGAGWEVVKVIWGRYWDP
HHHHHHHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCH
LLARDTSGKLLQLMEETVDGEYQNCKAKGGAYTREHFFGKYPETAEMVANMSDDDIWRLN
HHHCCCCHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHCCCCCCHHHHHHCCCCCCEEECC
RGGHDPVKVYAALEHAQKTKGRPTVILAKTVKGYGLGDAGEGKNIAHNVKKMGVESIRYF
CCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RDRFNIPIPDDQLEDLPFYHPGPDSEEVKYMMSRREALHGSVPQRRQKFTEEMEVPSLKI
HHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHH
FDSILQGSNGREISSTMAFVRVLTALLKDKKIGKNIVPIIPDEARTFGMEGLFRQVGIYA
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCEEE
HEGQKYVPQDSDQVAYYREDKTGQVLQEGINELGAMSSWVSAATSYSVNDTPMIPFYIYY
ECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
SMFGFQRIGDMAWAAGDMRARGFLVGGTSGRTTLNGEGLQHQDGHSHVLANTIPNCISYD
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEECCCCCCCCCCCCEEHHHHCCHHHCCC
PTYGYEIAVVVQDGIRRMYGENQEDIFYYLTTMNENYEQPAMPEGAEVGIVKGIYKLETV
CCCCCEEEEEEHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHH
AGSGKGKVQLMSCGTILEQTRKAAQALAKDFGITADVFSVTSFNELTRDGQAAERWNMLH
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHCCCCC
PTETPKQAYISQVISSDAPAIVATDYMKIYGEQLRAYIPTDYKVLGTDGFGRSDSRDNLR
CCCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHH
HHFEVDAKFIVIAALKSLVDRKELPVDVLVKAIKEYGIDADKINPQYA
HHEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]