Click here to switch to the map view.

The map label for this gene is mdtN [H]

Identifier: 126175964

GI number: 126175964

Start: 4426831

End: 4427889

Strand: Reverse

Name: mdtN [H]

Synonym: Sbal_3771

Alternate gene names: 126175964

Gene position: 4427889-4426831 (Counterclockwise)

Preceding gene: 126175965

Following gene: 126175963

Centisome position: 86.36

GC content: 52.03

Gene sequence:

>1059_bases
ATGACACCGGATCAACAGTTTGCCCGTTTAGTAAAATTCGCCATGTTCGGCTTTGTGATGGTTTTTGGCTATTTTATGCT
CGCCGATACTATGATGCCATTAACGCCGCAAGCTATGGCGACGCGTGTGGTGACTAAGGTCACGCCGCAGATCAGCGGCA
AAATTCAGACCATAGCCGTGACGAACAACCAAGCGGTTGCCAAGGGCGATTTGTTGTTTCAAGTCGATCCCGCGCCCTAT
GAGTTAGCGGTATCTCAAGCTAAATTAGCCTTAGAGCAAGCCCGCCAAGACAATGCCGAATTAGATGCCTCGTTGCTTGC
CGCGAAGGCCGACGTCAATGCCAACAAAACCACCTCACAACAGAAACGCAGCGAAGCTAAGCGCCTCGATGCTCTGTATG
CCACCCATGGTGTATCGCAGCAGCAAAGGGATCAGGCCGATAGTGATGCCGCCGCTGCGGAAGCAAATTTGCTCGCCGCC
AATGCGCGTTTAGAAAAACTTAAGGTGAGCCGTGGCAGTTATGGCGAAGAGAATCTTAAGGTGCGTCAGGCACAAAATCA
TCTTGCCCAAGCTGAGCTCAATTTGTCTTACACCCAAATCCATGCCGATCAGGACGGGATAGTGACTAACCTGCAGTTAG
AAGTCGGGAGTTTTGCGACCGTGGGGCAACCTCTGTTAGCCGTGGTATCGGATAAGATTGATATTATTGCTGATTTTCGT
GAAAAGAGTCTGCGCGGTGTCAATGCTTCATCGACCGCTTTGATTGCGTTTGATGGCGAACCCGGCCGTTTATATCGGGC
GACGGTGAGCAGTGTCGATGCGGGCGTGAGCGCGGGGCAATTCGATGCCAATGGCCGTTTAGCGGCGCCGCAGGAATCTG
ATCGTTGGGTGCGTGATGCCCAAAGATTGAGACTGCATTTGGAGTTAGATGGGATGGCGATGAACAGCTTGCCAGCCGGT
GCGCGCGCGACCGTACAACTGCTGCCCGAGAATAGCCTGTTTAGTCTACTGGCGAAGGTGCAGATTAAAGTCATTAGCCT
GCTGCACTATATTTATTAG

Upstream 100 bases:

>100_bases
CCAGCGAGCTCAGCGAATTTGAACGCATTATTAGCCTGATTAGTGACAACGCCAGCGCCAAATTGGCCAAGGCAACAGCA
ACCATTTTGTGAGAAAGAAG

Downstream 100 bases:

>100_bases
CCTATTTACTAGCCTATTTACTAGCTTATTTATCAGCCTATTTACTAGCGTATTGACTCGCCTATCTACTCGCACTAATT
GCTGTTGACGGGCGAGTGAC

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MTPDQQFARLVKFAMFGFVMVFGYFMLADTMMPLTPQAMATRVVTKVTPQISGKIQTIAVTNNQAVAKGDLLFQVDPAPY
ELAVSQAKLALEQARQDNAELDASLLAAKADVNANKTTSQQKRSEAKRLDALYATHGVSQQQRDQADSDAAAAEANLLAA
NARLEKLKVSRGSYGEENLKVRQAQNHLAQAELNLSYTQIHADQDGIVTNLQLEVGSFATVGQPLLAVVSDKIDIIADFR
EKSLRGVNASSTALIAFDGEPGRLYRATVSSVDAGVSAGQFDANGRLAAPQESDRWVRDAQRLRLHLELDGMAMNSLPAG
ARATVQLLPENSLFSLLAKVQIKVISLLHYIY

Sequences:

>Translated_352_residues
MTPDQQFARLVKFAMFGFVMVFGYFMLADTMMPLTPQAMATRVVTKVTPQISGKIQTIAVTNNQAVAKGDLLFQVDPAPY
ELAVSQAKLALEQARQDNAELDASLLAAKADVNANKTTSQQKRSEAKRLDALYATHGVSQQQRDQADSDAAAAEANLLAA
NARLEKLKVSRGSYGEENLKVRQAQNHLAQAELNLSYTQIHADQDGIVTNLQLEVGSFATVGQPLLAVVSDKIDIIADFR
EKSLRGVNASSTALIAFDGEPGRLYRATVSSVDAGVSAGQFDANGRLAAPQESDRWVRDAQRLRLHLELDGMAMNSLPAG
ARATVQLLPENSLFSLLAKVQIKVISLLHYIY
>Mature_351_residues
TPDQQFARLVKFAMFGFVMVFGYFMLADTMMPLTPQAMATRVVTKVTPQISGKIQTIAVTNNQAVAKGDLLFQVDPAPYE
LAVSQAKLALEQARQDNAELDASLLAAKADVNANKTTSQQKRSEAKRLDALYATHGVSQQQRDQADSDAAAAEANLLAAN
ARLEKLKVSRGSYGEENLKVRQAQNHLAQAELNLSYTQIHADQDGIVTNLQLEVGSFATVGQPLLAVVSDKIDIIADFRE
KSLRGVNASSTALIAFDGEPGRLYRATVSSVDAGVSAGQFDANGRLAAPQESDRWVRDAQRLRLHLELDGMAMNSLPAGA
RATVQLLPENSLFSLLAKVQIKVISLLHYIY

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790519, Length=310, Percent_Identity=30.9677419354839, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1790024, Length=360, Percent_Identity=26.1111111111111, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790012, Length=356, Percent_Identity=25.8426966292135, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789637, Length=326, Percent_Identity=29.4478527607362, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87081951, Length=299, Percent_Identity=27.0903010033445, Blast_Score=85, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 38187; Mature: 38056

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPDQQFARLVKFAMFGFVMVFGYFMLADTMMPLTPQAMATRVVTKVTPQISGKIQTIAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEEE
TNNQAVAKGDLLFQVDPAPYELAVSQAKLALEQARQDNAELDASLLAAKADVNANKTTSQ
ECCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHH
QKRSEAKRLDALYATHGVSQQQRDQADSDAAAAEANLLAANARLEKLKVSRGSYGEENLK
HHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHEECCCHHHHHCCCCCCCCCHHHH
VRQAQNHLAQAELNLSYTQIHADQDGIVTNLQLEVGSFATVGQPLLAVVSDKIDIIADFR
HHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCCCHHHCHHHHHHHHCCHHHHHHHH
EKSLRGVNASSTALIAFDGEPGRLYRATVSSVDAGVSAGQFDANGRLAAPQESDRWVRDA
HHHHCCCCCCCEEEEEEECCCCEEEEEEHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHH
QRLRLHLELDGMAMNSLPAGARATVQLLPENSLFSLLAKVQIKVISLLHYIY
HHEEEEEEECCEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TPDQQFARLVKFAMFGFVMVFGYFMLADTMMPLTPQAMATRVVTKVTPQISGKIQTIAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEEE
TNNQAVAKGDLLFQVDPAPYELAVSQAKLALEQARQDNAELDASLLAAKADVNANKTTSQ
ECCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHH
QKRSEAKRLDALYATHGVSQQQRDQADSDAAAAEANLLAANARLEKLKVSRGSYGEENLK
HHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHEECCCHHHHHCCCCCCCCCHHHH
VRQAQNHLAQAELNLSYTQIHADQDGIVTNLQLEVGSFATVGQPLLAVVSDKIDIIADFR
HHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCCCHHHCHHHHHHHHCCHHHHHHHH
EKSLRGVNASSTALIAFDGEPGRLYRATVSSVDAGVSAGQFDANGRLAAPQESDRWVRDA
HHHHCCCCCCCEEEEEEECCCCEEEEEEHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHH
QRLRLHLELDGMAMNSLPAGARATVQLLPENSLFSLLAKVQIKVISLLHYIY
HHEEEEEEECCEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]