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The map label for this gene is slyA [H]

Identifier: 126175965

GI number: 126175965

Start: 4427898

End: 4428371

Strand: Reverse

Name: slyA [H]

Synonym: Sbal_3772

Alternate gene names: 126175965

Gene position: 4428371-4427898 (Counterclockwise)

Preceding gene: 126175967

Following gene: 126175964

Centisome position: 86.37

GC content: 49.58

Gene sequence:

>474_bases
ATGCAAAAAGAATTAGAGCGATTGAAAGAGTTATCACTGGCGGAGCATTTAGGCCGTCTGCATCGATTGTGGCGTACCGT
GGCCGATGTCGAGCTGGCACCTTTGGGATTAACCCATCCCCGTTGGACGGCATTGTGGAAATTACTGCGTTTAGGCGACA
GCGTGAGCCAGAAAGTGTTGGCCGATGCCTTAGAAATTGAATTGGCTTCGCTAATGCGCACCTTAGGGCAATTAGAAGAG
CAAGGTTTAGTCGAGCGTCATTGCTGCGACAAAGATAAGCGCGCAAGGATTGTGACGCTAACGCCTGCGGGATTGGATGT
ATTAAAGCAAATGGAAGCGCGGATAATTCAGGTGCGCCGTGAGTTATTAGCTGGAATCAGTGCCAGCGAGCTCAGCGAAT
TTGAACGCATTATTAGCCTGATTAGTGACAACGCCAGCGCCAAATTGGCCAAGGCAACAGCAACCATTTTGTGA

Upstream 100 bases:

>100_bases
TTTTGCGCCATAGGACACAGAAAATTTTTTATATGAGCACATTTACTTAGCCTGCTAACTAAGTATAATGCTTAGCACGC
TAACTAAGTGGGTGAGCAAG

Downstream 100 bases:

>100_bases
GAAAGAAGATGACACCGGATCAACAGTTTGCCCGTTTAGTAAAATTCGCCATGTTCGGCTTTGTGATGGTTTTTGGCTAT
TTTATGCTCGCCGATACTAT

Product: MarR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MQKELERLKELSLAEHLGRLHRLWRTVADVELAPLGLTHPRWTALWKLLRLGDSVSQKVLADALEIELASLMRTLGQLEE
QGLVERHCCDKDKRARIVTLTPAGLDVLKQMEARIIQVRRELLAGISASELSEFERIISLISDNASAKLAKATATIL

Sequences:

>Translated_157_residues
MQKELERLKELSLAEHLGRLHRLWRTVADVELAPLGLTHPRWTALWKLLRLGDSVSQKVLADALEIELASLMRTLGQLEE
QGLVERHCCDKDKRARIVTLTPAGLDVLKQMEARIIQVRRELLAGISASELSEFERIISLISDNASAKLAKATATIL
>Mature_157_residues
MQKELERLKELSLAEHLGRLHRLWRTVADVELAPLGLTHPRWTALWKLLRLGDSVSQKVLADALEIELASLMRTLGQLEE
QGLVERHCCDKDKRARIVTLTPAGLDVLKQMEARIIQVRRELLAGISASELSEFERIISLISDNASAKLAKATATIL

Specific function: Transcription regulator that either activates or represses expression of target genes. Regulates the cpm operon, which contains the cpmA, cpmB, cpmC, cpmD, cpmE, cpmF, cpmG and cpmH, an operon involved in carbapenem-like antibiotic production [H]

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081950, Length=135, Percent_Identity=42.2222222222222, Blast_Score=97, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023071
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 17623; Mature: 17623

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: PS01117 HTH_MARR_1 ; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKELERLKELSLAEHLGRLHRLWRTVADVELAPLGLTHPRWTALWKLLRLGDSVSQKVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHH
ADALEIELASLMRTLGQLEEQGLVERHCCDKDKRARIVTLTPAGLDVLKQMEARIIQVRR
HHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHH
ELLAGISASELSEFERIISLISDNASAKLAKATATIL
HHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MQKELERLKELSLAEHLGRLHRLWRTVADVELAPLGLTHPRWTALWKLLRLGDSVSQKVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHH
ADALEIELASLMRTLGQLEEQGLVERHCCDKDKRARIVTLTPAGLDVLKQMEARIIQVRR
HHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHH
ELLAGISASELSEFERIISLISDNASAKLAKATATIL
HHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12147472; 14528314 [H]