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The map label for this gene is rnr [H]

Identifier: 126175842

GI number: 126175842

Start: 4268881

End: 4271304

Strand: Reverse

Name: rnr [H]

Synonym: Sbal_3647

Alternate gene names: 126175842

Gene position: 4271304-4268881 (Counterclockwise)

Preceding gene: 126175843

Following gene: 126175841

Centisome position: 83.3

GC content: 50.04

Gene sequence:

>2424_bases
ATGATCAAAGACCCTCATTTTGAGCGTGAACAGGATAAGTACGAAAACCCTATCCCAAGCCGTGAGTATATTATCGATTA
CTTACGTTCTCAGAAATCACCTATCACTCGTGACAGTATTGCCGCGGCGTTAAACATCCAAGAGGAAGAACAACTTGAGG
CCCTGCGCCGTCGCCTTCGTGCGATGGAACGCGATGGCGAACTCGTGTTCACCCGTGGGCAGAGCTATGGCTTGCCCGAG
AAAATGGATCTTATTCCCGGCACTGTACTCGGACACAGAGAAGGCTTCGGCTTTTTCAAACCCGATGAAGGCGGTGATGA
CTTATTTATTTCGAACCGCGATATGCTGATGTATTTCCACGGTGATAAAGTGCTGGCGCAAAAAGCGGGCACAGATCGTC
GTGGCCGTCGCGAAGCGCGTTTGGTGCGTTTGATCCAGCCGCGCAGTGCCGCGATTGTTGGCCGTTATCATGTTGATAGC
GGTATGGCATTTGTCATTGCCGATGATAAGCGTATTACCCAAGAAATCTTAGTCGCGAATGAAGATCGCAACGGCGCCCG
TCAAGGCGATGTGGTTGTGGTTGAATTAACGCGTCGCCCAGGTCGTTTTGTTAAGGCTGCGGGTAAAGTGACTGAAGTGC
TTGGTAAGCAAATGGCGCCGGGGATGGAAATCGAAATCGCCCTGCGTAACTATGACTTGCCCCATACTTGGTCACCTGTG
ATCGAGAAGAAACTGCGCCGAATTCCCGATGAAGTGACCGACGCCGATAAAGTCGGCCGTGTGGATTTACGTCATCTGCC
ATTAGTGACTATCGACGGCGAAGACGCCCGCGATTTTGACGATGCCGTGTATGCGGAGAAAAAAGCCGGTGGCGGCTGGC
GTTTATGGGTTGCGATTGCTGACGTTAGTTATTATGTTCGCACCGATTCGGCTTTAGATATCGAAGCGCGTGCCCGTGGT
AACTCAGTGTATTTCCCATCGCAAGTGATCCCTATGCTGCCGGAGAAAATCTCCAACGGCCTATGTTCGCTTAATCCTCA
CGTCGACCGTTTATGTATGGTCGCCGAAATGACAGTGTCTGCCAAAGGCAAGTTGTCGGGTTATAAGTTTTATCCGGCGG
TGATGTATTCCCATGCCCGTTTCACTTATACCCAAGTCGCGGAGATGTTTGAAGGCGGCCCGATTGCGCCTGAGCATGAA
GCCTTGTTCCCGCATCTGCAGTGTTTACAGTCATTGTATTTAGCGCTAGATGAGCAAAGAGCTGAGCGTGGTGCGATTGC
GTTTGAAACCATGGAAACGCAGTTCATTTTCAATGAGCAGCGCAAGATTGATAAAATCGTGCCGCGTGGCCGTAATCAAG
CACATAAAATCATTGAAGAATGCATGATTTTAGCCAACGTTTCTGCAGCTAAATTTGTGAAGAAACACAAAGGCGACGTG
CTGTACCGAGTGCATGAAGCGCCATCTGAGCAAAAGTTGGCGAACTTTAAAGAGTTCCTTGCTGAGCGTGGTTTGACTAT
GCCTGGCGGACTTGAGCCAACGCCGTCAGATTACCAGAACGTGATGCTGCAAATTGCCGACCGTCCCGATGCTGAACTTA
TCCAAGTGATGTTGCTGCGCTCTATGCGTCAGGCAATTTACACCCCAGATAATGAAGGTCACTTCGGTCTAGCCTTAGAA
GAATATGCGCATTTTACCTCGCCCATTCGCCGTTATCCGGATTTAGTCTTACATCGTGTGATCCGTTATTTACTGGCGAA
GGAAAGAGGCGAAGCCACAGAAAAGTGGACGCAGGATGGTGGCTACCACTATCAACTCGATGAACTCGACCAATTGGGCG
AAGAGTGTTCGACTACAGAACGGCGTGCCGATGAAGCGACTCGCGATGTTAGCGATTGGCTCAAGTGCGAGTTTATGCAA
GATCACGTCGGCGATACCTTCGAAGCTGTGATTGCCTCAGTGACGAGCTTTGGTTTGTTCGTGCGCTTAAATGAGCTGTT
TATCGATGGCTTAGTGCATATCTCAAGCCTAGGTAGTGATTACTACCAATTCGATCCTATGCGTCAACGCCTTATCGGTG
AGCATACAGGCCAAGTCTATCAAGTGGGCGATCCTGTGACGGTTAAGGTCGCTGCTGTTAACTTAGATGACAGACAGATT
GATTTAGTCATGCTGGGCGATGACGGCAAAGGTGGCAAGCGTAAAGCCTCTGCCAGCCGTGATAAGCCGATGACTGCCCG
TGAGCGTGTTAATCGCGAAGGTGCTAAGCAAGGCAAAGCGGGTAAAACCGCAACCCCTAGCACTAAGGCTGAAGCTGGCA
AAGCCAAACCTAAGGCTAAAGCGGGCACTAAAGCGAAAAAGACAGCAGTAAAAGATCCGGCTAAAAAGCCAAAAGCCGCT
AAGCGGAGCACGAGAAAGAAATAA

Upstream 100 bases:

>100_bases
AGCTAAAATGCCCCCCAGTGCAGTGGCGCGAGCCCAGCAAGAACAGTTGCGAACCCGTTAAGTGGTCTCTTAATCTAGAG
ACACATTATTTGGATATTGA

Downstream 100 bases:

>100_bases
ATGAAAAAACAAGATATTATTTTTGGGATCCACGCAGTTGAAGCCCTGTTAAAACACAGCCCTGAGCGCATTATCGAGTT
ATGGCTGTTACAAGGCCGTG

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R [H]

Number of amino acids: Translated: 807; Mature: 807

Protein sequence:

>807_residues
MIKDPHFEREQDKYENPIPSREYIIDYLRSQKSPITRDSIAAALNIQEEEQLEALRRRLRAMERDGELVFTRGQSYGLPE
KMDLIPGTVLGHREGFGFFKPDEGGDDLFISNRDMLMYFHGDKVLAQKAGTDRRGRREARLVRLIQPRSAAIVGRYHVDS
GMAFVIADDKRITQEILVANEDRNGARQGDVVVVELTRRPGRFVKAAGKVTEVLGKQMAPGMEIEIALRNYDLPHTWSPV
IEKKLRRIPDEVTDADKVGRVDLRHLPLVTIDGEDARDFDDAVYAEKKAGGGWRLWVAIADVSYYVRTDSALDIEARARG
NSVYFPSQVIPMLPEKISNGLCSLNPHVDRLCMVAEMTVSAKGKLSGYKFYPAVMYSHARFTYTQVAEMFEGGPIAPEHE
ALFPHLQCLQSLYLALDEQRAERGAIAFETMETQFIFNEQRKIDKIVPRGRNQAHKIIEECMILANVSAAKFVKKHKGDV
LYRVHEAPSEQKLANFKEFLAERGLTMPGGLEPTPSDYQNVMLQIADRPDAELIQVMLLRSMRQAIYTPDNEGHFGLALE
EYAHFTSPIRRYPDLVLHRVIRYLLAKERGEATEKWTQDGGYHYQLDELDQLGEECSTTERRADEATRDVSDWLKCEFMQ
DHVGDTFEAVIASVTSFGLFVRLNELFIDGLVHISSLGSDYYQFDPMRQRLIGEHTGQVYQVGDPVTVKVAAVNLDDRQI
DLVMLGDDGKGGKRKASASRDKPMTARERVNREGAKQGKAGKTATPSTKAEAGKAKPKAKAGTKAKKTAVKDPAKKPKAA
KRSTRKK

Sequences:

>Translated_807_residues
MIKDPHFEREQDKYENPIPSREYIIDYLRSQKSPITRDSIAAALNIQEEEQLEALRRRLRAMERDGELVFTRGQSYGLPE
KMDLIPGTVLGHREGFGFFKPDEGGDDLFISNRDMLMYFHGDKVLAQKAGTDRRGRREARLVRLIQPRSAAIVGRYHVDS
GMAFVIADDKRITQEILVANEDRNGARQGDVVVVELTRRPGRFVKAAGKVTEVLGKQMAPGMEIEIALRNYDLPHTWSPV
IEKKLRRIPDEVTDADKVGRVDLRHLPLVTIDGEDARDFDDAVYAEKKAGGGWRLWVAIADVSYYVRTDSALDIEARARG
NSVYFPSQVIPMLPEKISNGLCSLNPHVDRLCMVAEMTVSAKGKLSGYKFYPAVMYSHARFTYTQVAEMFEGGPIAPEHE
ALFPHLQCLQSLYLALDEQRAERGAIAFETMETQFIFNEQRKIDKIVPRGRNQAHKIIEECMILANVSAAKFVKKHKGDV
LYRVHEAPSEQKLANFKEFLAERGLTMPGGLEPTPSDYQNVMLQIADRPDAELIQVMLLRSMRQAIYTPDNEGHFGLALE
EYAHFTSPIRRYPDLVLHRVIRYLLAKERGEATEKWTQDGGYHYQLDELDQLGEECSTTERRADEATRDVSDWLKCEFMQ
DHVGDTFEAVIASVTSFGLFVRLNELFIDGLVHISSLGSDYYQFDPMRQRLIGEHTGQVYQVGDPVTVKVAAVNLDDRQI
DLVMLGDDGKGGKRKASASRDKPMTARERVNREGAKQGKAGKTATPSTKAEAGKAKPKAKAGTKAKKTAVKDPAKKPKAA
KRSTRKK
>Mature_807_residues
MIKDPHFEREQDKYENPIPSREYIIDYLRSQKSPITRDSIAAALNIQEEEQLEALRRRLRAMERDGELVFTRGQSYGLPE
KMDLIPGTVLGHREGFGFFKPDEGGDDLFISNRDMLMYFHGDKVLAQKAGTDRRGRREARLVRLIQPRSAAIVGRYHVDS
GMAFVIADDKRITQEILVANEDRNGARQGDVVVVELTRRPGRFVKAAGKVTEVLGKQMAPGMEIEIALRNYDLPHTWSPV
IEKKLRRIPDEVTDADKVGRVDLRHLPLVTIDGEDARDFDDAVYAEKKAGGGWRLWVAIADVSYYVRTDSALDIEARARG
NSVYFPSQVIPMLPEKISNGLCSLNPHVDRLCMVAEMTVSAKGKLSGYKFYPAVMYSHARFTYTQVAEMFEGGPIAPEHE
ALFPHLQCLQSLYLALDEQRAERGAIAFETMETQFIFNEQRKIDKIVPRGRNQAHKIIEECMILANVSAAKFVKKHKGDV
LYRVHEAPSEQKLANFKEFLAERGLTMPGGLEPTPSDYQNVMLQIADRPDAELIQVMLLRSMRQAIYTPDNEGHFGLALE
EYAHFTSPIRRYPDLVLHRVIRYLLAKERGEATEKWTQDGGYHYQLDELDQLGEECSTTERRADEATRDVSDWLKCEFMQ
DHVGDTFEAVIASVTSFGLFVRLNELFIDGLVHISSLGSDYYQFDPMRQRLIGEHTGQVYQVGDPVTVKVAAVNLDDRQI
DLVMLGDDGKGGKRKASASRDKPMTARERVNREGAKQGKAGKTATPSTKAEAGKAKPKAKAGTKAKKTAVKDPAKKPKAA
KRSTRKK

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=398, Percent_Identity=30.6532663316583, Blast_Score=168, Evalue=2e-41,
Organism=Homo sapiens, GI190014625, Length=401, Percent_Identity=30.1745635910224, Blast_Score=168, Evalue=2e-41,
Organism=Homo sapiens, GI134288890, Length=408, Percent_Identity=30.1470588235294, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI19115966, Length=509, Percent_Identity=24.950884086444, Blast_Score=141, Evalue=3e-33,
Organism=Homo sapiens, GI219521928, Length=509, Percent_Identity=24.950884086444, Blast_Score=140, Evalue=5e-33,
Organism=Homo sapiens, GI156105695, Length=557, Percent_Identity=24.4165170556553, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI156105693, Length=557, Percent_Identity=24.4165170556553, Blast_Score=74, Evalue=5e-13,
Organism=Escherichia coli, GI87082383, Length=749, Percent_Identity=59.0120160213618, Blast_Score=927, Evalue=0.0,
Organism=Escherichia coli, GI1787542, Length=645, Percent_Identity=26.9767441860465, Blast_Score=182, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI212645896, Length=405, Percent_Identity=28.8888888888889, Blast_Score=162, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI17553506, Length=467, Percent_Identity=28.4796573875803, Blast_Score=153, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6324552, Length=553, Percent_Identity=26.5822784810127, Blast_Score=156, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6320499, Length=555, Percent_Identity=21.8018018018018, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24649634, Length=398, Percent_Identity=29.3969849246231, Blast_Score=162, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24654592, Length=360, Percent_Identity=27.7777777777778, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI19922976, Length=360, Percent_Identity=27.7777777777778, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24654597, Length=360, Percent_Identity=27.7777777777778, Blast_Score=127, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 91002; Mature: 91002

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKDPHFEREQDKYENPIPSREYIIDYLRSQKSPITRDSIAAALNIQEEEQLEALRRRLR
CCCCCCCCCHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
AMERDGELVFTRGQSYGLPEKMDLIPGTVLGHREGFGFFKPDEGGDDLFISNRDMLMYFH
HHCCCCCEEEECCCCCCCCCHHHCCCCCEECCCCCCCCCCCCCCCCEEEEECCCEEEEEC
GDKVLAQKAGTDRRGRREARLVRLIQPRSAAIVGRYHVDSGMAFVIADDKRITQEILVAN
CCCHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEECCHHHHHHHHEEC
EDRNGARQGDVVVVELTRRPGRFVKAAGKVTEVLGKQMAPGMEIEIALRNYDLPHTWSPV
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHH
IEKKLRRIPDEVTDADKVGRVDLRHLPLVTIDGEDARDFDDAVYAEKKAGGGWRLWVAIA
HHHHHHHCCHHHCCCHHCCCCEECCCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEEE
DVSYYVRTDSALDIEARARGNSVYFPSQVIPMLPEKISNGLCSLNPHVDRLCMVAEMTVS
EEEEEEECCCCEEEEECCCCCEEECCHHHHHHCHHHHCCCCCCCCCCHHHHHHHHHHHHC
AKGKLSGYKFYPAVMYSHARFTYTQVAEMFEGGPIAPEHEALFPHLQCLQSLYLALDEQR
CCCCCCCEEEHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AERGAIAFETMETQFIFNEQRKIDKIVPRGRNQAHKIIEECMILANVSAAKFVKKHKGDV
HHCCCEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCE
LYRVHEAPSEQKLANFKEFLAERGLTMPGGLEPTPSDYQNVMLQIADRPDAELIQVMLLR
EEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHH
SMRQAIYTPDNEGHFGLALEEYAHFTSPIRRYPDLVLHRVIRYLLAKERGEATEKWTQDG
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
GYHYQLDELDQLGEECSTTERRADEATRDVSDWLKCEFMQDHVGDTFEAVIASVTSFGLF
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VRLNELFIDGLVHISSLGSDYYQFDPMRQRLIGEHTGQVYQVGDPVTVKVAAVNLDDRQI
HHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHCCCCEEECCCCEEEEEEEEECCCCEE
DLVMLGDDGKGGKRKASASRDKPMTARERVNREGAKQGKAGKTATPSTKAEAGKAKPKAK
EEEEECCCCCCCCCCCCCCCCCCCHHHHHHCHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
AGTKAKKTAVKDPAKKPKAAKRSTRKK
CCCCHHHHHHCCCCCCCCHHHHHCCCC
>Mature Secondary Structure
MIKDPHFEREQDKYENPIPSREYIIDYLRSQKSPITRDSIAAALNIQEEEQLEALRRRLR
CCCCCCCCCHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
AMERDGELVFTRGQSYGLPEKMDLIPGTVLGHREGFGFFKPDEGGDDLFISNRDMLMYFH
HHCCCCCEEEECCCCCCCCCHHHCCCCCEECCCCCCCCCCCCCCCCEEEEECCCEEEEEC
GDKVLAQKAGTDRRGRREARLVRLIQPRSAAIVGRYHVDSGMAFVIADDKRITQEILVAN
CCCHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEECCHHHHHHHHEEC
EDRNGARQGDVVVVELTRRPGRFVKAAGKVTEVLGKQMAPGMEIEIALRNYDLPHTWSPV
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHH
IEKKLRRIPDEVTDADKVGRVDLRHLPLVTIDGEDARDFDDAVYAEKKAGGGWRLWVAIA
HHHHHHHCCHHHCCCHHCCCCEECCCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEEE
DVSYYVRTDSALDIEARARGNSVYFPSQVIPMLPEKISNGLCSLNPHVDRLCMVAEMTVS
EEEEEEECCCCEEEEECCCCCEEECCHHHHHHCHHHHCCCCCCCCCCHHHHHHHHHHHHC
AKGKLSGYKFYPAVMYSHARFTYTQVAEMFEGGPIAPEHEALFPHLQCLQSLYLALDEQR
CCCCCCCEEEHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AERGAIAFETMETQFIFNEQRKIDKIVPRGRNQAHKIIEECMILANVSAAKFVKKHKGDV
HHCCCEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCE
LYRVHEAPSEQKLANFKEFLAERGLTMPGGLEPTPSDYQNVMLQIADRPDAELIQVMLLR
EEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHH
SMRQAIYTPDNEGHFGLALEEYAHFTSPIRRYPDLVLHRVIRYLLAKERGEATEKWTQDG
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
GYHYQLDELDQLGEECSTTERRADEATRDVSDWLKCEFMQDHVGDTFEAVIASVTSFGLF
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VRLNELFIDGLVHISSLGSDYYQFDPMRQRLIGEHTGQVYQVGDPVTVKVAAVNLDDRQI
HHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHCCCCEEECCCCEEEEEEEEECCCCEE
DLVMLGDDGKGGKRKASASRDKPMTARERVNREGAKQGKAGKTATPSTKAEAGKAKPKAK
EEEEECCCCCCCCCCCCCCCCCCCHHHHHHCHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
AGTKAKKTAVKDPAKKPKAAKRSTRKK
CCCCHHHHHHCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]