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The map label for this gene is mrdB [H]

Identifier: 126175476

GI number: 126175476

Start: 3838419

End: 3839525

Strand: Direct

Name: mrdB [H]

Synonym: Sbal_3276

Alternate gene names: 126175476

Gene position: 3838419-3839525 (Clockwise)

Preceding gene: 126175475

Following gene: 126175477

Centisome position: 74.86

GC content: 48.69

Gene sequence:

>1107_bases
ATGAGTACCCATAGCCAATATCAAAACATCTGGCAACGCTTGCACATAGATTTGCCATTATTGCTCGGCCTATTGGCTGT
GATGGGCTTTGGCCTGTTCGTCATCTATTCTGCCAGCGGCGAAGATTTAGAGATGATGGAGCGGCAGCTGTTCCGTATGG
TGTTATCGCTCGGCATCATGTTCACTATGGCGCAAATCAATCCTGAAGCGCTTAAGCGTTGGGCCTTACCCATTTATCTG
GCGGGGATTGTCTTGCTGCTTGGGGTGCACTTTTTCGGTGAAATCAACAAAGGCGCGCAGCGCTGGTTGAACTTAGGCTT
TATGGAGTTTCAACCCTCAGAGCTGATTAAACTCGCCTTCCCCATCACTATGGCTTGGTATATCAGTAAGTTCCCTCTGC
CGCCGAAGAAACGCTATCTTGCGGGTGCGGCGGTGATCTTGCTGGTGCCGACTCTACTTATCGCTAAACAACCAGACCTC
GGCACATCGATTTTGGTGGCTGCATCAGGCATTTTCGTGCTGTTTTTATCCGGCATGAGCTGGCTCATTGTTGGTGGTTT
TATCGCCGCAGTGCTCGCCTTCCTGCCTATCCTTTGGTATTTCTTGATGCACGATTACCAAAGAACACGGGTATTGACCC
TGCTCGATCCTGAGCAAGATCCCCTCGGCGCGGGTTACCACATTATTCAGTCGAAAATCGCTATCGGCTCTGGCGGACTC
TGGGGCAAAGGTTGGCTCGACGGCACTCAGTCACAGCTTGAATTTATCCCTGAACGTCATACCGATTTTATCTTTGCGGT
GATCGGTGAAGAATTTGGCTTAATTGGCAGTATCTTACTGTTAATTATGTACCTCTATATTATTGGCCGCGGTTTAGTCA
TTGCTTCGCGCGCCCAAACCAGTTTTGCTCGACTGCTCGCAGGTAGTATCACGCTGACTTTTTTCGTTTATGTTTTTGTG
AATATTGGCATGGTTTCAGGTATCCTGCCCGTGGTAGGTGTACCACTGCCCCTTGTCAGTTATGGTGGAACCTCCATGCT
GACATTGATGACAGGGTTTGGCATTCTTATGAGCATTCATACCCATAGACGTTTCGTAGATAGATAA

Upstream 100 bases:

>100_bases
TCGTGATGGAAAACGCAGGTTGGGGCGGCGCAAATGCTGGCCCCGTCGCTCGCGCCATGCTCGATGAATATATGCTTAGA
GATACTTGGAAACCGCAACC

Downstream 100 bases:

>100_bases
TTTTTAGGGACTTTTCATGCCTACTCTCCGAGCTTTTTTAGCTCCACTCGGTTTACTGTGTTTTAGTTCATTGTTAGTCG
CCTGTACCACGGCGAACGAA

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MSTHSQYQNIWQRLHIDLPLLLGLLAVMGFGLFVIYSASGEDLEMMERQLFRMVLSLGIMFTMAQINPEALKRWALPIYL
AGIVLLLGVHFFGEINKGAQRWLNLGFMEFQPSELIKLAFPITMAWYISKFPLPPKKRYLAGAAVILLVPTLLIAKQPDL
GTSILVAASGIFVLFLSGMSWLIVGGFIAAVLAFLPILWYFLMHDYQRTRVLTLLDPEQDPLGAGYHIIQSKIAIGSGGL
WGKGWLDGTQSQLEFIPERHTDFIFAVIGEEFGLIGSILLLIMYLYIIGRGLVIASRAQTSFARLLAGSITLTFFVYVFV
NIGMVSGILPVVGVPLPLVSYGGTSMLTLMTGFGILMSIHTHRRFVDR

Sequences:

>Translated_368_residues
MSTHSQYQNIWQRLHIDLPLLLGLLAVMGFGLFVIYSASGEDLEMMERQLFRMVLSLGIMFTMAQINPEALKRWALPIYL
AGIVLLLGVHFFGEINKGAQRWLNLGFMEFQPSELIKLAFPITMAWYISKFPLPPKKRYLAGAAVILLVPTLLIAKQPDL
GTSILVAASGIFVLFLSGMSWLIVGGFIAAVLAFLPILWYFLMHDYQRTRVLTLLDPEQDPLGAGYHIIQSKIAIGSGGL
WGKGWLDGTQSQLEFIPERHTDFIFAVIGEEFGLIGSILLLIMYLYIIGRGLVIASRAQTSFARLLAGSITLTFFVYVFV
NIGMVSGILPVVGVPLPLVSYGGTSMLTLMTGFGILMSIHTHRRFVDR
>Mature_367_residues
STHSQYQNIWQRLHIDLPLLLGLLAVMGFGLFVIYSASGEDLEMMERQLFRMVLSLGIMFTMAQINPEALKRWALPIYLA
GIVLLLGVHFFGEINKGAQRWLNLGFMEFQPSELIKLAFPITMAWYISKFPLPPKKRYLAGAAVILLVPTLLIAKQPDLG
TSILVAASGIFVLFLSGMSWLIVGGFIAAVLAFLPILWYFLMHDYQRTRVLTLLDPEQDPLGAGYHIIQSKIAIGSGGLW
GKGWLDGTQSQLEFIPERHTDFIFAVIGEEFGLIGSILLLIMYLYIIGRGLVIASRAQTSFARLLAGSITLTFFVYVFVN
IGMVSGILPVVGVPLPLVSYGGTSMLTLMTGFGILMSIHTHRRFVDR

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=368, Percent_Identity=60.054347826087, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1786277, Length=306, Percent_Identity=36.9281045751634, Blast_Score=172, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40891; Mature: 40759

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTHSQYQNIWQRLHIDLPLLLGLLAVMGFGLFVIYSASGEDLEMMERQLFRMVLSLGIM
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHH
FTMAQINPEALKRWALPIYLAGIVLLLGVHFFGEINKGAQRWLNLGFMEFQPSELIKLAF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEECHHHHHHHHH
PITMAWYISKFPLPPKKRYLAGAAVILLVPTLLIAKQPDLGTSILVAASGIFVLFLSGMS
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
WLIVGGFIAAVLAFLPILWYFLMHDYQRTRVLTLLDPEQDPLGAGYHIIQSKIAIGSGGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHEECCCCC
WGKGWLDGTQSQLEFIPERHTDFIFAVIGEEFGLIGSILLLIMYLYIIGRGLVIASRAQT
CCCCCCCCCHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHH
SFARLLAGSITLTFFVYVFVNIGMVSGILPVVGVPLPLVSYGGTSMLTLMTGFGILMSIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHH
THRRFVDR
HHHHHCCC
>Mature Secondary Structure 
STHSQYQNIWQRLHIDLPLLLGLLAVMGFGLFVIYSASGEDLEMMERQLFRMVLSLGIM
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHH
FTMAQINPEALKRWALPIYLAGIVLLLGVHFFGEINKGAQRWLNLGFMEFQPSELIKLAF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEECHHHHHHHHH
PITMAWYISKFPLPPKKRYLAGAAVILLVPTLLIAKQPDLGTSILVAASGIFVLFLSGMS
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
WLIVGGFIAAVLAFLPILWYFLMHDYQRTRVLTLLDPEQDPLGAGYHIIQSKIAIGSGGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHEECCCCC
WGKGWLDGTQSQLEFIPERHTDFIFAVIGEEFGLIGSILLLIMYLYIIGRGLVIASRAQT
CCCCCCCCCHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHH
SFARLLAGSITLTFFVYVFVNIGMVSGILPVVGVPLPLVSYGGTSMLTLMTGFGILMSIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHH
THRRFVDR
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]