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The map label for this gene is ushA [C]

Identifier: 126175197

GI number: 126175197

Start: 3522769

End: 3524514

Strand: Direct

Name: ushA [C]

Synonym: Sbal_2995

Alternate gene names: 126175197

Gene position: 3522769-3524514 (Clockwise)

Preceding gene: 126175196

Following gene: 126175199

Centisome position: 68.71

GC content: 50.0

Gene sequence:

>1746_bases
ATGACACAGGGTTACACACTCTCACTCGCGCACATCAATGACACCCATTCGAATTTTGAACCCAGCCGCGTCCAATTTAA
CCTTAACATCGGCCAGCATAAGCTTGATGTAACCAGCCATAGCGGTGGTTATGCCCGCATCGGCCATCACATCACTAAGG
CACGTCAAGCCGCCGCACAAACCGATACGCCGTTTATTTTCCTGCACGGTGGTGACAGCTTCCAAGGCACGCTTTATTTC
AGCCATTTTAAAGGCAAGGCCAACGCCCACTTACTTAATCTGTTAGCGCCCGATGCTATGGTCATTGGCAACCACGATAT
CGATGAAGGTAACGCCAGACTTGCCGAGTTTGCTAAGCAGATTGATTTCCCATTGCTTGCGGGCAACATGGATTTAAGCC
AAGAAGATCTCAACAAACCCGGTTGTCTGCGCGGTTTGCCTAATATCTTGGATTATGATCATCAGCAAAAACGCGCGAAA
TACCTGCTTAAGCCTTTCCACGATAAGACGTTAGCCATTGTCGGTATTACCTTAGATCAAATGAAAGAGATCGCTCGCCC
CGATCCCGACACTCATTTTGTCGATGCTATAGCCACAACCGCACGCACGGTTGAGCACCTTAAAAATCAAGGTATTAAAC
ATATCATAGTGCTCAGTCACTTAGGCTTAGATCAAGATAAACGCCTCGCGGCCGAAGTGGAGGGTATTAGCCTTATCGTC
GGTGGTCACACGCATACGCTACAGGGCGATTTTCGCGCCTTAGGTTTGAGCAACCTGCCCTACGGTGAAGTCATCAACAA
CACGCCGATAGTGCATGCGGGTAAATATGCCGAAGTCGTCGGCTTAGCCGAGATAACGTTTGACGCTGAAGGCAAAGTGC
TGAGTCTAACAGGCGGCAACTATTTCATGCTGGATCAACACTTTATCTTAAGTGCTAACACAGCTGTCGATAATCAAGAT
TACCAAGCGGTGCGCCAACAGCTCAGTCAGCACCCAAATGTCCTTTGGGATGATGCCGATGCCGATATTGATGGCGTGAT
CCGAGACATCTATAAACCCGCCATCGCGGATATGGAGAACAAAGTCTTAGCACTGGTGCCAAAAAACTTAGTCCATACAC
GCTTGCCCTCTAAGGCTCTGCCCCACGGCAGTGAAGTTGCGCCATGGGTCAGTCGCAGCATGTTCCAAGAAGCTAAGCTT
GTTGATCCTAGGGTAAACTTTGCCCTGCATAATGCTGGCGGTGTGCGCCAGTCAGTAGCCCAAGGCCAGTTGACGTTGGC
GGATGTGATGGGGCAATTACTGCCCTTCGAATTGCCGCTGGTTAAGTATGAAATTCAAGGTCAATTCCTCTATCAAGCGC
TCGAATCGGCGATTAACGCGGCGACCAACAACAGCGTCCGTGGCACTGGTGCGGGTAGCTTCCCTTACACCTACGGCTTA
CGGTATTACTACGATGGCCGGCGTCCACTGGGCGAGCGTTTATTTAGATTGGAGATGATGCAGCAGGACAGCCAATCTCT
TTGGTATCCCGTTGAGCCTGAGTCACTGTATGTCGGGGTATCGACGTCTTACACTGCTGCGGGTAAGGAAGGCTATCATC
CATTACTGCAAGCCCGCTGGCAGGAGTCGATGGAGTCTCTGACATTGCCACAAGCCTTTATTCGATTTTTAAATCGCTCA
CCGAATCTGTCTGATTTACTGTCACAGCACGTGCATTACACCAGCCACAGCCAACGTATGGGTTAA

Upstream 100 bases:

>100_bases
TCCCTTTATTCTTTTAGAATGCAAATGACTCAGAACCGTCTGAACCTCGCATTTTGAGGTCGCTTGGGTATATACTCACC
CGCCGTAATAGAGGTAAGTT

Downstream 100 bases:

>100_bases
GTGCCAAGGCTCCTCATGGCGTCAACATTGATGCAGTGAGGAGCAAAGTAAATGAATGAGTGACTGGGTAACAGTCTTCC
TTACAAAGCGTTGAATAGAC

Product: 5'-nucleotidase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 581; Mature: 580

Protein sequence:

>581_residues
MTQGYTLSLAHINDTHSNFEPSRVQFNLNIGQHKLDVTSHSGGYARIGHHITKARQAAAQTDTPFIFLHGGDSFQGTLYF
SHFKGKANAHLLNLLAPDAMVIGNHDIDEGNARLAEFAKQIDFPLLAGNMDLSQEDLNKPGCLRGLPNILDYDHQQKRAK
YLLKPFHDKTLAIVGITLDQMKEIARPDPDTHFVDAIATTARTVEHLKNQGIKHIIVLSHLGLDQDKRLAAEVEGISLIV
GGHTHTLQGDFRALGLSNLPYGEVINNTPIVHAGKYAEVVGLAEITFDAEGKVLSLTGGNYFMLDQHFILSANTAVDNQD
YQAVRQQLSQHPNVLWDDADADIDGVIRDIYKPAIADMENKVLALVPKNLVHTRLPSKALPHGSEVAPWVSRSMFQEAKL
VDPRVNFALHNAGGVRQSVAQGQLTLADVMGQLLPFELPLVKYEIQGQFLYQALESAINAATNNSVRGTGAGSFPYTYGL
RYYYDGRRPLGERLFRLEMMQQDSQSLWYPVEPESLYVGVSTSYTAAGKEGYHPLLQARWQESMESLTLPQAFIRFLNRS
PNLSDLLSQHVHYTSHSQRMG

Sequences:

>Translated_581_residues
MTQGYTLSLAHINDTHSNFEPSRVQFNLNIGQHKLDVTSHSGGYARIGHHITKARQAAAQTDTPFIFLHGGDSFQGTLYF
SHFKGKANAHLLNLLAPDAMVIGNHDIDEGNARLAEFAKQIDFPLLAGNMDLSQEDLNKPGCLRGLPNILDYDHQQKRAK
YLLKPFHDKTLAIVGITLDQMKEIARPDPDTHFVDAIATTARTVEHLKNQGIKHIIVLSHLGLDQDKRLAAEVEGISLIV
GGHTHTLQGDFRALGLSNLPYGEVINNTPIVHAGKYAEVVGLAEITFDAEGKVLSLTGGNYFMLDQHFILSANTAVDNQD
YQAVRQQLSQHPNVLWDDADADIDGVIRDIYKPAIADMENKVLALVPKNLVHTRLPSKALPHGSEVAPWVSRSMFQEAKL
VDPRVNFALHNAGGVRQSVAQGQLTLADVMGQLLPFELPLVKYEIQGQFLYQALESAINAATNNSVRGTGAGSFPYTYGL
RYYYDGRRPLGERLFRLEMMQQDSQSLWYPVEPESLYVGVSTSYTAAGKEGYHPLLQARWQESMESLTLPQAFIRFLNRS
PNLSDLLSQHVHYTSHSQRMG
>Mature_580_residues
TQGYTLSLAHINDTHSNFEPSRVQFNLNIGQHKLDVTSHSGGYARIGHHITKARQAAAQTDTPFIFLHGGDSFQGTLYFS
HFKGKANAHLLNLLAPDAMVIGNHDIDEGNARLAEFAKQIDFPLLAGNMDLSQEDLNKPGCLRGLPNILDYDHQQKRAKY
LLKPFHDKTLAIVGITLDQMKEIARPDPDTHFVDAIATTARTVEHLKNQGIKHIIVLSHLGLDQDKRLAAEVEGISLIVG
GHTHTLQGDFRALGLSNLPYGEVINNTPIVHAGKYAEVVGLAEITFDAEGKVLSLTGGNYFMLDQHFILSANTAVDNQDY
QAVRQQLSQHPNVLWDDADADIDGVIRDIYKPAIADMENKVLALVPKNLVHTRLPSKALPHGSEVAPWVSRSMFQEAKLV
DPRVNFALHNAGGVRQSVAQGQLTLADVMGQLLPFELPLVKYEIQGQFLYQALESAINAATNNSVRGTGAGSFPYTYGLR
YYYDGRRPLGERLFRLEMMQQDSQSLWYPVEPESLYVGVSTSYTAAGKEGYHPLLQARWQESMESLTLPQAFIRFLNRSP
NLSDLLSQHVHYTSHSQRMG

Specific function: Degradation Of External Udp-Glucose To Uridine Monophosphate And Glucose-1-Phosphate, Which Can Then Be Used By The Cell. [C]

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Homo sapiens, GI4505467, Length=548, Percent_Identity=24.6350364963504, Blast_Score=126, Evalue=7e-29,
Organism=Drosophila melanogaster, GI28573524, Length=545, Percent_Identity=28.6238532110092, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24641187, Length=550, Percent_Identity=26.9090909090909, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI19922444, Length=563, Percent_Identity=24.866785079929, Blast_Score=139, Evalue=7e-33,
Organism=Drosophila melanogaster, GI19922446, Length=519, Percent_Identity=25.4335260115607, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24654424, Length=519, Percent_Identity=25.4335260115607, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI221329836, Length=593, Percent_Identity=24.6205733558179, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR004843
- InterPro:   IPR006420 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 64498; Mature: 64367

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQGYTLSLAHINDTHSNFEPSRVQFNLNIGQHKLDVTSHSGGYARIGHHITKARQAAAQ
CCCCEEEEEEEECCCCCCCCCCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHC
TDTPFIFLHGGDSFQGTLYFSHFKGKANAHLLNLLAPDAMVIGNHDIDEGNARLAEFAKQ
CCCCEEEEECCCCCCEEEEEEECCCCCCCEEEEEECCCEEEECCCCCCCCCHHHHHHHHH
IDFPLLAGNMDLSQEDLNKPGCLRGLPNILDYDHQQKRAKYLLKPFHDKTLAIVGITLDQ
CCCCEEECCCCCCHHHCCCCCHHHCCCHHHCCCCHHHHHHHHHCCCCCCEEEEEEEEHHH
MKEIARPDPDTHFVDAIATTARTVEHLKNQGIKHIIVLSHLGLDQDKRLAAEVEGISLIV
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHCCCCEEEEE
GGHTHTLQGDFRALGLSNLPYGEVINNTPIVHAGKYAEVVGLAEITFDAEGKVLSLTGGN
CCCEEEECCCHHEECCCCCCCCHHHCCCCEEECCCHHHHEEEEEEEECCCCCEEEEECCC
YFMLDQHFILSANTAVDNQDYQAVRQQLSQHPNVLWDDADADIDGVIRDIYKPAIADMEN
EEEEECEEEEECCCCCCCHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHCCCC
KVLALVPKNLVHTRLPSKALPHGSEVAPWVSRSMFQEAKLVDPRVNFALHNAGGVRQSVA
CEEEEECHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHH
QGQLTLADVMGQLLPFELPLVKYEIQGQFLYQALESAINAATNNSVRGTGAGSFPYTYGL
CCCEEHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECE
RYYYDGRRPLGERLFRLEMMQQDSQSLWYPVEPESLYVGVSTSYTAAGKEGYHPLLQARW
EEEECCCCCHHHHHHHHHHHHCCCCCCEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHH
QESMESLTLPQAFIRFLNRSPNLSDLLSQHVHYTSHSQRMG
HHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TQGYTLSLAHINDTHSNFEPSRVQFNLNIGQHKLDVTSHSGGYARIGHHITKARQAAAQ
CCCEEEEEEEECCCCCCCCCCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHC
TDTPFIFLHGGDSFQGTLYFSHFKGKANAHLLNLLAPDAMVIGNHDIDEGNARLAEFAKQ
CCCCEEEEECCCCCCEEEEEEECCCCCCCEEEEEECCCEEEECCCCCCCCCHHHHHHHHH
IDFPLLAGNMDLSQEDLNKPGCLRGLPNILDYDHQQKRAKYLLKPFHDKTLAIVGITLDQ
CCCCEEECCCCCCHHHCCCCCHHHCCCHHHCCCCHHHHHHHHHCCCCCCEEEEEEEEHHH
MKEIARPDPDTHFVDAIATTARTVEHLKNQGIKHIIVLSHLGLDQDKRLAAEVEGISLIV
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHCCCCEEEEE
GGHTHTLQGDFRALGLSNLPYGEVINNTPIVHAGKYAEVVGLAEITFDAEGKVLSLTGGN
CCCEEEECCCHHEECCCCCCCCHHHCCCCEEECCCHHHHEEEEEEEECCCCCEEEEECCC
YFMLDQHFILSANTAVDNQDYQAVRQQLSQHPNVLWDDADADIDGVIRDIYKPAIADMEN
EEEEECEEEEECCCCCCCHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHCCCC
KVLALVPKNLVHTRLPSKALPHGSEVAPWVSRSMFQEAKLVDPRVNFALHNAGGVRQSVA
CEEEEECHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHH
QGQLTLADVMGQLLPFELPLVKYEIQGQFLYQALESAINAATNNSVRGTGAGSFPYTYGL
CCCEEHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECE
RYYYDGRRPLGERLFRLEMMQQDSQSLWYPVEPESLYVGVSTSYTAAGKEGYHPLLQARW
EEEECCCCCHHHHHHHHHHHHCCCCCCEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHH
QESMESLTLPQAFIRFLNRSPNLSDLLSQHVHYTSHSQRMG
HHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]