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The map label for this gene is lepB [H]

Identifier: 126174893

GI number: 126174893

Start: 3147276

End: 3147938

Strand: Reverse

Name: lepB [H]

Synonym: Sbal_2685

Alternate gene names: 126174893

Gene position: 3147938-3147276 (Counterclockwise)

Preceding gene: 126174894

Following gene: 126174889

Centisome position: 61.39

GC content: 47.96

Gene sequence:

>663_bases
ATGTTCAAAGGAATAACAAAACTACTTAAGGATAACCGCTCCTTTTTATTGTTTATCAGCTTAATGTTAGTGTTCAGGAG
CGCTGTGGCTGATTGGAATACCGTGCCATCGGGTTCTATGCTGCCGACTATCGTCGAGGGCGATCGCATTCTGGTGAACA
AGATGGCCTACGATCTTAGGGTGCCATTTACCCATATCGCCTTAGTCAAACTGGCGGATCCCGCCCGCGGTGATATCGTG
GTGTTCGATTCGAAAAAGGCCGATAAAAAACTCATTAAGCGGGTGATTGCTGTGCCAGGCGATACTGTGATGATGCGGGA
TAATCGTTTGTATTTAAATGGCGAACCCCTTAGTTACGCATCCCAAGCATTGAGTCCTTATGCTCCCGCTGATGTCATAG
AAATGCAGGAGAACTTACTCGGTATGGTTCACAGTATTCGCCTTAATCCTGTCCCCTCAAAGCTCGCCAATGTTGGACCT
GTCACTGTGCCAGACGCGCATTATCTAGCGCTGGGTGATAATCGAGATAATAGCGCAGACTCTCGGGTCATTGGCTTTGT
GCCACGGGATGAAATTGTTGGCCGTTCAAGCTCAGTGGTTTTCTCCCTCGATTATGATGATCATTACCTGCCTCGACCTG
AGCGTCTCATACGCGAGTTTTAG

Upstream 100 bases:

>100_bases
ATCTGTGCTTAAGCAGGTATCAACAGAACTTAGTGCAACGCAATGGGTCTATTTAACTGAGAACAGCGACTAGCTTATAC
ATGCCATAGAGAGGGAATAT

Downstream 100 bases:

>100_bases
CATTTACGATTTTGTACCATAAAGAAGGGCGCCGAATGAGGCGCCCTTTTGTTAGCTGATTGATTCAAAATGCTTTACTT
CAAAGCAACTACTTCATAAA

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MFKGITKLLKDNRSFLLFISLMLVFRSAVADWNTVPSGSMLPTIVEGDRILVNKMAYDLRVPFTHIALVKLADPARGDIV
VFDSKKADKKLIKRVIAVPGDTVMMRDNRLYLNGEPLSYASQALSPYAPADVIEMQENLLGMVHSIRLNPVPSKLANVGP
VTVPDAHYLALGDNRDNSADSRVIGFVPRDEIVGRSSSVVFSLDYDDHYLPRPERLIREF

Sequences:

>Translated_220_residues
MFKGITKLLKDNRSFLLFISLMLVFRSAVADWNTVPSGSMLPTIVEGDRILVNKMAYDLRVPFTHIALVKLADPARGDIV
VFDSKKADKKLIKRVIAVPGDTVMMRDNRLYLNGEPLSYASQALSPYAPADVIEMQENLLGMVHSIRLNPVPSKLANVGP
VTVPDAHYLALGDNRDNSADSRVIGFVPRDEIVGRSSSVVFSLDYDDHYLPRPERLIREF
>Mature_220_residues
MFKGITKLLKDNRSFLLFISLMLVFRSAVADWNTVPSGSMLPTIVEGDRILVNKMAYDLRVPFTHIALVKLADPARGDIV
VFDSKKADKKLIKRVIAVPGDTVMMRDNRLYLNGEPLSYASQALSPYAPADVIEMQENLLGMVHSIRLNPVPSKLANVGP
VTVPDAHYLALGDNRDNSADSRVIGFVPRDEIVGRSSSVVFSLDYDDHYLPRPERLIREF

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=261, Percent_Identity=30.6513409961686, Blast_Score=108, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 24555; Mature: 24555

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKGITKLLKDNRSFLLFISLMLVFRSAVADWNTVPSGSMLPTIVEGDRILVNKMAYDLR
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEEHHHHHEE
VPFTHIALVKLADPARGDIVVFDSKKADKKLIKRVIAVPGDTVMMRDNRLYLNGEPLSYA
CCHHHEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCEEEECCCCHHHH
SQALSPYAPADVIEMQENLLGMVHSIRLNPVPSKLANVGPVTVPDAHYLALGDNRDNSAD
HHHCCCCCCHHHHHHHHHHHHHHHHEECCCCCHHHHCCCCCCCCCCEEEEECCCCCCCCC
SRVIGFVPRDEIVGRSSSVVFSLDYDDHYLPRPERLIREF
CCEEEECCCHHHCCCCCCEEEEECCCCCCCCCHHHHHHCC
>Mature Secondary Structure
MFKGITKLLKDNRSFLLFISLMLVFRSAVADWNTVPSGSMLPTIVEGDRILVNKMAYDLR
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEEHHHHHEE
VPFTHIALVKLADPARGDIVVFDSKKADKKLIKRVIAVPGDTVMMRDNRLYLNGEPLSYA
CCHHHEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCEEEECCCCHHHH
SQALSPYAPADVIEMQENLLGMVHSIRLNPVPSKLANVGPVTVPDAHYLALGDNRDNSAD
HHHCCCCCCHHHHHHHHHHHHHHHHEECCCCCHHHHCCCCCCCCCCEEEEECCCCCCCCC
SRVIGFVPRDEIVGRSSSVVFSLDYDDHYLPRPERLIREF
CCEEEECCCHHHCCCCCCEEEEECCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]