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The map label for this gene is gmhB [H]

Identifier: 126174845

GI number: 126174845

Start: 3089046

End: 3089594

Strand: Reverse

Name: gmhB [H]

Synonym: Sbal_2632

Alternate gene names: 126174845

Gene position: 3089594-3089046 (Counterclockwise)

Preceding gene: 126174848

Following gene: 126174842

Centisome position: 60.26

GC content: 46.27

Gene sequence:

>549_bases
GTGAGTCGAGCAGTATTTTTAGACCGTGATGGCGTGATTAACAAAGATCATGGTTATGTCCACTTAGTGGATGACTTCGA
ATATATCGAAGGTGTGTTTGAATCTTGCCTCTCTTTGAAGGAAATGGGCTACAAGTTAGTTGTCGTCACCAATCAATCTG
GCATTGCCCGTGGTATGTACACAGAAGATCAATTCCATAGCTTAACGGAGTGGATGGATTGGAACTTTGCCGACAAAGGC
GTTGAACTCGATGGTATCTACTATTGCCCGCACCATGCTAAAAATGGCATAGGGGAATATAAGGTCGACTGTGATTGCCG
CAAACCTAAGCCGGGTATGCTCAATGATGCGGCGCAATTCTTGAAAATCGACTTAGTGCACTCAGTCATGGTTGGCGACA
AAGCCGAAGATATGCAAGCAGCGAAAGCGGCTGGCGTGACCACACGTATATTAGTGCGCAGTGGTAAGGTTATTGCTGAT
GACAGTGATGCCACAGTGGTACTGGACAGTATTGCCGATGTGCCGGCTTACTTAAAAAGCTTAGGCTAG

Upstream 100 bases:

>100_bases
ACGCTCAATTTAGCGCTAAAAGCACAACTTCGCGGTGCAATTTTTGATAATGAATGGAATAATAGCGCGATAACGCCTTA
GGCGATTTTGGAGTATTACA

Downstream 100 bases:

>100_bases
TCGCTGCACTACATAAGCAGATAAACATTTGCTGATAAGTTCATCTCAAGCAGCAACTATCACAGTAACCAGTAGCGCGA
GTTGTCGCTCTTGTTGGATT

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MSRAVFLDRDGVINKDHGYVHLVDDFEYIEGVFESCLSLKEMGYKLVVVTNQSGIARGMYTEDQFHSLTEWMDWNFADKG
VELDGIYYCPHHAKNGIGEYKVDCDCRKPKPGMLNDAAQFLKIDLVHSVMVGDKAEDMQAAKAAGVTTRILVRSGKVIAD
DSDATVVLDSIADVPAYLKSLG

Sequences:

>Translated_182_residues
MSRAVFLDRDGVINKDHGYVHLVDDFEYIEGVFESCLSLKEMGYKLVVVTNQSGIARGMYTEDQFHSLTEWMDWNFADKG
VELDGIYYCPHHAKNGIGEYKVDCDCRKPKPGMLNDAAQFLKIDLVHSVMVGDKAEDMQAAKAAGVTTRILVRSGKVIAD
DSDATVVLDSIADVPAYLKSLG
>Mature_181_residues
SRAVFLDRDGVINKDHGYVHLVDDFEYIEGVFESCLSLKEMGYKLVVVTNQSGIARGMYTEDQFHSLTEWMDWNFADKGV
ELDGIYYCPHHAKNGIGEYKVDCDCRKPKPGMLNDAAQFLKIDLVHSVMVGDKAEDMQAAKAAGVTTRILVRSGKVIADD
SDATVVLDSIADVPAYLKSLG

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=178, Percent_Identity=60.1123595505618, Blast_Score=229, Evalue=8e-62,
Organism=Escherichia coli, GI87082027, Length=149, Percent_Identity=31.5436241610738, Blast_Score=84, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.1.1.-

Molecular weight: Translated: 20157; Mature: 20026

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRAVFLDRDGVINKDHGYVHLVDDFEYIEGVFESCLSLKEMGYKLVVVTNQSGIARGMY
CCCEEEEECCCCEECCCCEEEEECCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCC
TEDQFHSLTEWMDWNFADKGVELDGIYYCPHHAKNGIGEYKVDCDCRKPKPGMLNDAAQF
CCHHHHHHHHHHCCCCCCCCEEECEEEECCCCCCCCCCCEEEECCCCCCCCCCHHHHHHH
LKIDLVHSVMVGDKAEDMQAAKAAGVTTRILVRSGKVIADDSDATVVLDSIADVPAYLKS
HHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEEECCCEEECCCCCEEEEHHHHHHHHHHHH
LG
CC
>Mature Secondary Structure 
SRAVFLDRDGVINKDHGYVHLVDDFEYIEGVFESCLSLKEMGYKLVVVTNQSGIARGMY
CCEEEEECCCCEECCCCEEEEECCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCC
TEDQFHSLTEWMDWNFADKGVELDGIYYCPHHAKNGIGEYKVDCDCRKPKPGMLNDAAQF
CCHHHHHHHHHHCCCCCCCCEEECEEEECCCCCCCCCCCEEEECCCCCCCCCCHHHHHHH
LKIDLVHSVMVGDKAEDMQAAKAAGVTTRILVRSGKVIADDSDATVVLDSIADVPAYLKS
HHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEEECCCEEECCCCCEEEEHHHHHHHHHHHH
LG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301; 12101286 [H]