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The map label for this gene is dcp [H]

Identifier: 126174842

GI number: 126174842

Start: 3076627

End: 3078771

Strand: Reverse

Name: dcp [H]

Synonym: Sbal_2629

Alternate gene names: 126174842

Gene position: 3078771-3076627 (Counterclockwise)

Preceding gene: 126174845

Following gene: 126174839

Centisome position: 60.05

GC content: 47.23

Gene sequence:

>2145_bases
ATGCGTAAGTCCGTTATAACCACAGCCGTGGCCGCGGCTTTGTTACTTGGCGCTTGTTCAGACAAGCCAGCCGCCAGTGC
CAATGAAGCCAAAAATGCCGTAGCGACTCAAACTGCTGCTAAAGCACAAGCAACCAATGTGTTGCTGGGCAAGAGTCCAC
TGCAGGATCAAGCGCCACAATTTAACCTTATCCATACAGCAGATTATGCTCCTGCCTTCGAGCAAGGCATTAAAGCCCAT
GATGCTGAAATCGCTGCCATTGTGAATAACAAGCAAGCGGCCAGTTTTGACAACACCATTCTGGCGATGGAAACCTCGGG
TGAATTATTAACGCGGGTGTCGCGGACCTTCTTTAATCTCGCCGGTCTGATTTCTGATGATGATTTCCAGAAAACCGAAG
CAGATCTTGCACCTAAGCTATCTGCCCATCGCGATAATATTTATCTCGATCCGACGTTATTTGCCCGTGTTGAAGCGGTA
TATCAACAAAAAAGCAGCTTAAATACGGAAGATCAGCGTCTAGTTGAATACTACTATGAGCAGTTTGTTCGAGCTGGCGC
GAAATTGTCGGCTGAAGATAAAGCTAAAATGCGCGACTTTAACGCCGAGCTTGCAACCTTAGCGACGGACTTTTCACAAA
ACAGCTTAAAATCATTTAAAGATGATGTGATTGTTGTGACTGATAAAGCCCAGTTAGCTGGTTTATCTGACAGCGAAATC
GCCACCTTAGCCGCTGCCGCTAAAGCTGCTGGAAAAGAGGGCTATTTGATTACCTTAGTGAACACGACTCGCCAGCCTGT
GCTTTCTAGCCTGAGCAACCGTGAACTGCGCCAAAAAGTGTGGGAAACCTCGGCGCACAGAGCTGTTGCAACCAATGGCC
CATTGATTGTTAAAATGGCGCAAATTCGGGCTAAAAAAGCCAACTTATTGGGATTCGATACTTGGGCATCCTATGCGGTT
GCCGATCAAATGGCGAAAACCCCTGCCGCTGTGTATGAAATCCTCGATGATTTAGCGCCAAAAGCCTTGGCTCGTGCCAA
AGTGGAAGCAGCTGATATTCAAGCCGAAATCAAAAAGGCGGGCGGTGATTTCGAACTGCAACCTTGGGATTGGGCTTACT
ACGCCGACAAAGTACGTAAAGAGAAATACGATCTCGACGAAAGCAGCATCAAGCCTTATTTCGAGTTTAATACTGTGCTG
CAAGACGGGCTGTTTTTCGCGATGCATAAACTGTATGGCATCAGCTTAAAAGCGCGTACCGATTTACCCGTGTGGAATCC
CGATGTTTTAGCCTTTGAAGTCTTTGATAAAGACAACAGCTCTATTGGCTTATTCTACCTTGACCCTTATGCCCGTGAAG
GCAAAGGCGGCGGCGCGTGGATGGATGAGTTCGTCACCCAAAGCGGTCTGCTTGGCACTAAGCCCGTTGTTTATAACGCG
CTGAATATTCCTAAGCCAGCCGATGGCCCAACGTTAATGACATTCGATGAAGTGACCACTATGTTCCATGAAATGGGTCA
TGCGGTTCACGGTTTATTCTCGCAGGTGAAATACCCAAGCGTGGCTGGCACATCAACCGCACGTGACTTTGTTGAGTTCC
CATCCCAGGTTAACGAAGATTGGAATATCGATCCTGCTGTGATTGCTAACTATGCCAAACACTACAAGACGGGTGAGCCA
ATTCCTAAGGCACTGCTTGATAAAATCTTAGCCTCAAATAAGTTTGGCCAAGGTTTTGATACCGTTGAGTATCTGTCAGC
TGCCTTGTTAGATATGGAATGGCACTCTATCAGCGCCGATACTCAAATTAGCGATGTAGAGAAGTTTGAGCACCAAGTGT
TAGCTAAACACGGCCTCGATTTTGCGCCAATTCCCCCGCGTTATAAATCGAGCTACTTTAGCCATGCCTTCTCCGGCGGT
TATTCAGCTGGATATTACGCGTATTTGTGGACCGAAGTGTTTGCCGCCGATGCCTTTGCCTACATGGGCGAGCACGGTGG
ATTAAAAGCCGATAATGGTGACAAATTCCGTAAGGAAGTCTTATCTAAAGGTAACAGTGAAGATCTCATGCAAGATTACA
TTCACTTTACCGGTAAAAAGCCGACAACAGATGCACTGTTAAAGCGCCGCGGTTTAGTCGACTAA

Upstream 100 bases:

>100_bases
TTGACTCAGACTGTTTTAAACTGAAAGCCAAAATCCGTTAGCGCGCACCTTTCACCTTAAAAATACAAACGAAAGGGCAG
CAACATCCAAGGGAGTTAAT

Downstream 100 bases:

>100_bases
TCGATTCGTTGTAAAAAGGCCCAAAGGCTTGTTAGGGAAACCTAGCAAGCCTTTTTTATTGATGTCGGGGCGGATTTATT
CATCATTTTTTCAAGACAGG

Product: peptidyl-dipeptidase Dcp

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 714; Mature: 714

Protein sequence:

>714_residues
MRKSVITTAVAAALLLGACSDKPAASANEAKNAVATQTAAKAQATNVLLGKSPLQDQAPQFNLIHTADYAPAFEQGIKAH
DAEIAAIVNNKQAASFDNTILAMETSGELLTRVSRTFFNLAGLISDDDFQKTEADLAPKLSAHRDNIYLDPTLFARVEAV
YQQKSSLNTEDQRLVEYYYEQFVRAGAKLSAEDKAKMRDFNAELATLATDFSQNSLKSFKDDVIVVTDKAQLAGLSDSEI
ATLAAAAKAAGKEGYLITLVNTTRQPVLSSLSNRELRQKVWETSAHRAVATNGPLIVKMAQIRAKKANLLGFDTWASYAV
ADQMAKTPAAVYEILDDLAPKALARAKVEAADIQAEIKKAGGDFELQPWDWAYYADKVRKEKYDLDESSIKPYFEFNTVL
QDGLFFAMHKLYGISLKARTDLPVWNPDVLAFEVFDKDNSSIGLFYLDPYAREGKGGGAWMDEFVTQSGLLGTKPVVYNA
LNIPKPADGPTLMTFDEVTTMFHEMGHAVHGLFSQVKYPSVAGTSTARDFVEFPSQVNEDWNIDPAVIANYAKHYKTGEP
IPKALLDKILASNKFGQGFDTVEYLSAALLDMEWHSISADTQISDVEKFEHQVLAKHGLDFAPIPPRYKSSYFSHAFSGG
YSAGYYAYLWTEVFAADAFAYMGEHGGLKADNGDKFRKEVLSKGNSEDLMQDYIHFTGKKPTTDALLKRRGLVD

Sequences:

>Translated_714_residues
MRKSVITTAVAAALLLGACSDKPAASANEAKNAVATQTAAKAQATNVLLGKSPLQDQAPQFNLIHTADYAPAFEQGIKAH
DAEIAAIVNNKQAASFDNTILAMETSGELLTRVSRTFFNLAGLISDDDFQKTEADLAPKLSAHRDNIYLDPTLFARVEAV
YQQKSSLNTEDQRLVEYYYEQFVRAGAKLSAEDKAKMRDFNAELATLATDFSQNSLKSFKDDVIVVTDKAQLAGLSDSEI
ATLAAAAKAAGKEGYLITLVNTTRQPVLSSLSNRELRQKVWETSAHRAVATNGPLIVKMAQIRAKKANLLGFDTWASYAV
ADQMAKTPAAVYEILDDLAPKALARAKVEAADIQAEIKKAGGDFELQPWDWAYYADKVRKEKYDLDESSIKPYFEFNTVL
QDGLFFAMHKLYGISLKARTDLPVWNPDVLAFEVFDKDNSSIGLFYLDPYAREGKGGGAWMDEFVTQSGLLGTKPVVYNA
LNIPKPADGPTLMTFDEVTTMFHEMGHAVHGLFSQVKYPSVAGTSTARDFVEFPSQVNEDWNIDPAVIANYAKHYKTGEP
IPKALLDKILASNKFGQGFDTVEYLSAALLDMEWHSISADTQISDVEKFEHQVLAKHGLDFAPIPPRYKSSYFSHAFSGG
YSAGYYAYLWTEVFAADAFAYMGEHGGLKADNGDKFRKEVLSKGNSEDLMQDYIHFTGKKPTTDALLKRRGLVD
>Mature_714_residues
MRKSVITTAVAAALLLGACSDKPAASANEAKNAVATQTAAKAQATNVLLGKSPLQDQAPQFNLIHTADYAPAFEQGIKAH
DAEIAAIVNNKQAASFDNTILAMETSGELLTRVSRTFFNLAGLISDDDFQKTEADLAPKLSAHRDNIYLDPTLFARVEAV
YQQKSSLNTEDQRLVEYYYEQFVRAGAKLSAEDKAKMRDFNAELATLATDFSQNSLKSFKDDVIVVTDKAQLAGLSDSEI
ATLAAAAKAAGKEGYLITLVNTTRQPVLSSLSNRELRQKVWETSAHRAVATNGPLIVKMAQIRAKKANLLGFDTWASYAV
ADQMAKTPAAVYEILDDLAPKALARAKVEAADIQAEIKKAGGDFELQPWDWAYYADKVRKEKYDLDESSIKPYFEFNTVL
QDGLFFAMHKLYGISLKARTDLPVWNPDVLAFEVFDKDNSSIGLFYLDPYAREGKGGGAWMDEFVTQSGLLGTKPVVYNA
LNIPKPADGPTLMTFDEVTTMFHEMGHAVHGLFSQVKYPSVAGTSTARDFVEFPSQVNEDWNIDPAVIANYAKHYKTGEP
IPKALLDKILASNKFGQGFDTVEYLSAALLDMEWHSISADTQISDVEKFEHQVLAKHGLDFAPIPPRYKSSYFSHAFSGG
YSAGYYAYLWTEVFAADAFAYMGEHGGLKADNGDKFRKEVLSKGNSEDLMQDYIHFTGKKPTTDALLKRRGLVD

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=638, Percent_Identity=30.7210031347962, Blast_Score=254, Evalue=2e-67,
Organism=Homo sapiens, GI14149738, Length=642, Percent_Identity=29.9065420560748, Blast_Score=229, Evalue=6e-60,
Organism=Homo sapiens, GI156105687, Length=422, Percent_Identity=29.3838862559242, Blast_Score=171, Evalue=2e-42,
Organism=Escherichia coli, GI1787819, Length=675, Percent_Identity=46.962962962963, Blast_Score=616, Evalue=1e-177,
Organism=Escherichia coli, GI1789913, Length=693, Percent_Identity=33.044733044733, Blast_Score=355, Evalue=6e-99,
Organism=Caenorhabditis elegans, GI32565901, Length=597, Percent_Identity=23.9530988274707, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71999758, Length=580, Percent_Identity=20.6896551724138, Blast_Score=75, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319793, Length=595, Percent_Identity=29.9159663865546, Blast_Score=219, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6322715, Length=645, Percent_Identity=23.2558139534884, Blast_Score=144, Evalue=4e-35,
Organism=Drosophila melanogaster, GI20129717, Length=395, Percent_Identity=30.126582278481, Blast_Score=170, Evalue=3e-42,
Organism=Drosophila melanogaster, GI21356111, Length=473, Percent_Identity=26.6384778012685, Blast_Score=156, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 78554; Mature: 78554

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKSVITTAVAAALLLGACSDKPAASANEAKNAVATQTAAKAQATNVLLGKSPLQDQAPQ
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCC
FNLIHTADYAPAFEQGIKAHDAEIAAIVNNKQAASFDNTILAMETSGELLTRVSRTFFNL
EEEEECCCCCHHHHHCCHHCCCEEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHH
AGLISDDDFQKTEADLAPKLSAHRDNIYLDPTLFARVEAVYQQKSSLNTEDQRLVEYYYE
HHCCCCCCHHHHHHHHCCCCCCCCCCEEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QFVRAGAKLSAEDKAKMRDFNAELATLATDFSQNSLKSFKDDVIVVTDKAQLAGLSDSEI
HHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHCHHHHHHHCCCEEEEECCHHHCCCCCHHH
ATLAAAAKAAGKEGYLITLVNTTRQPVLSSLSNRELRQKVWETSAHRAVATNGPLIVKMA
HHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEHH
QIRAKKANLLGFDTWASYAVADQMAKTPAAVYEILDDLAPKALARAKVEAADIQAEIKKA
HHHHHHHCEEEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGDFELQPWDWAYYADKVRKEKYDLDESSIKPYFEFNTVLQDGLFFAMHKLYGISLKART
CCCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEECC
DLPVWNPDVLAFEVFDKDNSSIGLFYLDPYAREGKGGGAWMDEFVTQSGLLGTKPVVYNA
CCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCHHEEC
LNIPKPADGPTLMTFDEVTTMFHEMGHAVHGLFSQVKYPSVAGTSTARDFVEFPSQVNED
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCC
WNIDPAVIANYAKHYKTGEPIPKALLDKILASNKFGQGFDTVEYLSAALLDMEWHSISAD
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCHHCCCCCC
TQISDVEKFEHQVLAKHGLDFAPIPPRYKSSYFSHAFSGGYSAGYYAYLWTEVFAADAFA
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
YMGEHGGLKADNGDKFRKEVLSKGNSEDLMQDYIHFTGKKPTTDALLKRRGLVD
HHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure
MRKSVITTAVAAALLLGACSDKPAASANEAKNAVATQTAAKAQATNVLLGKSPLQDQAPQ
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCC
FNLIHTADYAPAFEQGIKAHDAEIAAIVNNKQAASFDNTILAMETSGELLTRVSRTFFNL
EEEEECCCCCHHHHHCCHHCCCEEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHH
AGLISDDDFQKTEADLAPKLSAHRDNIYLDPTLFARVEAVYQQKSSLNTEDQRLVEYYYE
HHCCCCCCHHHHHHHHCCCCCCCCCCEEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QFVRAGAKLSAEDKAKMRDFNAELATLATDFSQNSLKSFKDDVIVVTDKAQLAGLSDSEI
HHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHCHHHHHHHCCCEEEEECCHHHCCCCCHHH
ATLAAAAKAAGKEGYLITLVNTTRQPVLSSLSNRELRQKVWETSAHRAVATNGPLIVKMA
HHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEHH
QIRAKKANLLGFDTWASYAVADQMAKTPAAVYEILDDLAPKALARAKVEAADIQAEIKKA
HHHHHHHCEEEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGDFELQPWDWAYYADKVRKEKYDLDESSIKPYFEFNTVLQDGLFFAMHKLYGISLKART
CCCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEECC
DLPVWNPDVLAFEVFDKDNSSIGLFYLDPYAREGKGGGAWMDEFVTQSGLLGTKPVVYNA
CCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCHHEEC
LNIPKPADGPTLMTFDEVTTMFHEMGHAVHGLFSQVKYPSVAGTSTARDFVEFPSQVNED
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCC
WNIDPAVIANYAKHYKTGEPIPKALLDKILASNKFGQGFDTVEYLSAALLDMEWHSISAD
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCHHCCCCCC
TQISDVEKFEHQVLAKHGLDFAPIPPRYKSSYFSHAFSGGYSAGYYAYLWTEVFAADAFA
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
YMGEHGGLKADNGDKFRKEVLSKGNSEDLMQDYIHFTGKKPTTDALLKRRGLVD
HHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]