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The map label for this gene is pepV [H]

Identifier: 126174839

GI number: 126174839

Start: 3070852

End: 3071694

Strand: Reverse

Name: pepV [H]

Synonym: Sbal_2626

Alternate gene names: 126174839

Gene position: 3071694-3070852 (Counterclockwise)

Preceding gene: 126174842

Following gene: 126174838

Centisome position: 59.91

GC content: 47.45

Gene sequence:

>843_bases
ATGTCTCAATCTGGTATTCAACATGCTCGCGTGCGTCGAGCGTTATCTTTGGCATTACTGACTGCGTCCAGCTGGGTTAT
GCCGCAGTGTATTGCAGCGCCAGCAACAACAGCGGCTCAAACAAACGTCCCCCAGTTAAGCCAAAATGCACTAAAGGTCG
CCGATTATGCGGTCGCAAAATACGATGCGGCTATGGTGCAGAGTTTGACTCAGTTGGTGAGTTTTAATACCCAAGCGGTT
GAAGGGCAAACGCCAGATACCAATCCCGCCTTTGTGGGCTTCAAGTCGAGTTTAAAGCAACTCAGTCAGGATCTCGGGTT
AGATTATGCCGATCATGGTTATGTTGTGTTGATTGGCTTAGATGCCAATTCGGCTGTAAACAATGAATCTAAAAAGTTAG
GCATAGTCACCCACGGCGATGTGCAACCAGCTAATCCTGCATTGTGGGCGAAGAGCCCTTATCTGCTTGATACTCAATCG
GAACCGGGCAAACTGATTGGTCGCGGCACAGAGGACGACAAGGGCGCCATCGTTACCGCCATGTATGCGATGAAGGCGAT
TAAAGATAAACACATTAAGCGAGATAGACGCATTGAACTCTTGGTTTATCTTGCTGAAGAGTCCGACTGGGAACCACTGA
AAACCTTTTTAGCCAGCTACACGCCAGCGGACATGAACATTACTATCGATGCCGAATACCCCGTGGTTACCGCCGAGAAA
GGTTGGAGTAAGATTACCTTTACTGTGCCCAATATTACGATCTCCAATATAGAAGCTAAAGCAGAGGCTTCAACTCCCCC
TGTGTCAGGATTGTTGTCACCCCTAAATAATCATTATTTTTAA

Upstream 100 bases:

>100_bases
ACTGGTATAAGCAACACGTTGCAGTAAACCAGCTTAATCCATTTTCAACCGTCTCTTGCAGTACGGTCCTAAAACACGAA
TAACAATAATAGGATCTTCT

Downstream 100 bases:

>100_bases
AGACAGGGTGCGGCAAAAGAGAATGATATGGCTCGGTATTCACCAGAACGTAAAGAGGCGATCCTTAAAAAATTATTACC
TCCTCACAACTTAACGGTCG

Product: dipeptidase

Products: NA

Alternate protein names: Beta-Ala-His dipeptidase; Peptidase V [H]

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MSQSGIQHARVRRALSLALLTASSWVMPQCIAAPATTAAQTNVPQLSQNALKVADYAVAKYDAAMVQSLTQLVSFNTQAV
EGQTPDTNPAFVGFKSSLKQLSQDLGLDYADHGYVVLIGLDANSAVNNESKKLGIVTHGDVQPANPALWAKSPYLLDTQS
EPGKLIGRGTEDDKGAIVTAMYAMKAIKDKHIKRDRRIELLVYLAEESDWEPLKTFLASYTPADMNITIDAEYPVVTAEK
GWSKITFTVPNITISNIEAKAEASTPPVSGLLSPLNNHYF

Sequences:

>Translated_280_residues
MSQSGIQHARVRRALSLALLTASSWVMPQCIAAPATTAAQTNVPQLSQNALKVADYAVAKYDAAMVQSLTQLVSFNTQAV
EGQTPDTNPAFVGFKSSLKQLSQDLGLDYADHGYVVLIGLDANSAVNNESKKLGIVTHGDVQPANPALWAKSPYLLDTQS
EPGKLIGRGTEDDKGAIVTAMYAMKAIKDKHIKRDRRIELLVYLAEESDWEPLKTFLASYTPADMNITIDAEYPVVTAEK
GWSKITFTVPNITISNIEAKAEASTPPVSGLLSPLNNHYF
>Mature_279_residues
SQSGIQHARVRRALSLALLTASSWVMPQCIAAPATTAAQTNVPQLSQNALKVADYAVAKYDAAMVQSLTQLVSFNTQAVE
GQTPDTNPAFVGFKSSLKQLSQDLGLDYADHGYVVLIGLDANSAVNNESKKLGIVTHGDVQPANPALWAKSPYLLDTQSE
PGKLIGRGTEDDKGAIVTAMYAMKAIKDKHIKRDRRIELLVYLAEESDWEPLKTFLASYTPADMNITIDAEYPVVTAEKG
WSKITFTVPNITISNIEAKAEASTPPVSGLLSPLNNHYF

Specific function: Is a relatively unspecific dipeptidase cleaving a variety of dipeptides, notably those with an N-terminal beta-Ala or D-Ala residue, e.g. carnosine (beta-Ala-His). To a lesser extent, also shows aminopeptidase activity, since it is able to catalyze the re

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR011291
- InterPro:   IPR010964
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF01546 Peptidase_M20 [H]

EC number: NA

Molecular weight: Translated: 30308; Mature: 30176

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSGIQHARVRRALSLALLTASSWVMPQCIAAPATTAAQTNVPQLSQNALKVADYAVAK
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHHH
YDAAMVQSLTQLVSFNTQAVEGQTPDTNPAFVGFKSSLKQLSQDLGLDYADHGYVVLIGL
HHHHHHHHHHHHHHCCCCEECCCCCCCCCEEECHHHHHHHHHHHHCCCCCCCCEEEEEEE
DANSAVNNESKKLGIVTHGDVQPANPALWAKSPYLLDTQSEPGKLIGRGTEDDKGAIVTA
CCCCCCCCCCCEEEEEEECCCCCCCCCEECCCCEEEECCCCCCCEEECCCCCCCCHHHHH
MYAMKAIKDKHIKRDRRIELLVYLAEESDWEPLKTFLASYTPADMNITIDAEYPVVTAEK
HHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCEEECCC
GWSKITFTVPNITISNIEAKAEASTPPVSGLLSPLNNHYF
CCCEEEEEECCEEEECCEEECCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
SQSGIQHARVRRALSLALLTASSWVMPQCIAAPATTAAQTNVPQLSQNALKVADYAVAK
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHHH
YDAAMVQSLTQLVSFNTQAVEGQTPDTNPAFVGFKSSLKQLSQDLGLDYADHGYVVLIGL
HHHHHHHHHHHHHHCCCCEECCCCCCCCCEEECHHHHHHHHHHHHCCCCCCCCEEEEEEE
DANSAVNNESKKLGIVTHGDVQPANPALWAKSPYLLDTQSEPGKLIGRGTEDDKGAIVTA
CCCCCCCCCCCEEEEEEECCCCCCCCCEECCCCEEEECCCCCCCEEECCCCCCCCHHHHH
MYAMKAIKDKHIKRDRRIELLVYLAEESDWEPLKTFLASYTPADMNITIDAEYPVVTAEK
HHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCEEECCC
GWSKITFTVPNITISNIEAKAEASTPPVSGLLSPLNNHYF
CCCEEEEEECCEEEECCEEECCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7528082 [H]