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The map label for this gene is rtn [H]

Identifier: 126174490

GI number: 126174490

Start: 2632814

End: 2633518

Strand: Direct

Name: rtn [H]

Synonym: Sbal_2274

Alternate gene names: 126174490

Gene position: 2632814-2633518 (Clockwise)

Preceding gene: 126174489

Following gene: 126174491

Centisome position: 51.35

GC content: 47.8

Gene sequence:

>705_bases
ATGATTAACCTTAGTTCGTTAACGCTCAGCTGCGAATACCAACCCTTTGTCGATCCCCATACGTTAGCCATCGACGGCTA
TGAAGCCTTAGCGCGTTTTTATCTACCTGATGGCGATGCGGTTGCACCTAATATCGTGTTCGAGCAATTGCATGAATCCA
CAGAATTACTCGCCGCCGTTGAATATCAAGCCAAAGCATTTCAACTCGCTCACGCACCCAGCCAGCAGCGCATTTTTATC
AATGTCGATCCCCACGCCGTCGATGGACCACATACCGCCAAGCTCATTCGTTTACTGTCCCACTATGAACGAGTCACGGT
CGAGATCATTGAAAATACCTGCATTAACGATGCCCAGCTTGCCAATCAGCTATTCAGCCAATTTAAACAAGCAGATATCA
AGGTAGCGCTCGACGATATTGGTGCGCCCCACTCCATGCTTTGTGTCGATTTGATGATGAATGTGGATTATCTCAAGTTC
GATCGCCATTGGTTAACCCACATCACGCATTCCGAGGGAGTCCAGTTACTCATAGCGCTGATTAACTTTGCCAAGCAAAC
CAATAAACAGTGCATTCTAGAAGGCATAGAAACCGAAGCCCACTTGGCGTTTGCGCGAGACATAGGCGTCGACTTAGTCC
AAGGCTTTTTGTTTAAATCTTGGTTTATTCGCCCCACCCGCAGTCAAGCGCTGTGTCTTGCATAG

Upstream 100 bases:

>100_bases
ATTATTCAGCAATCACGCCGTTTTATCGTAAACTTGTTTGCACTGCGAGGCATTAAATGCGAATAATTAGTATTAATGCA
TTAAGACTCCCATTAGGCCC

Downstream 100 bases:

>100_bases
ATCCACGCGCCGCCCTTTGACTTTGCGCCACCAGCACACGCAAGCCTAAACGTCATTCAGTCGAGTAATTGATTTCGCAC
TAGAAATGCCACTGGATAAG

Product: diguanylate phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MINLSSLTLSCEYQPFVDPHTLAIDGYEALARFYLPDGDAVAPNIVFEQLHESTELLAAVEYQAKAFQLAHAPSQQRIFI
NVDPHAVDGPHTAKLIRLLSHYERVTVEIIENTCINDAQLANQLFSQFKQADIKVALDDIGAPHSMLCVDLMMNVDYLKF
DRHWLTHITHSEGVQLLIALINFAKQTNKQCILEGIETEAHLAFARDIGVDLVQGFLFKSWFIRPTRSQALCLA

Sequences:

>Translated_234_residues
MINLSSLTLSCEYQPFVDPHTLAIDGYEALARFYLPDGDAVAPNIVFEQLHESTELLAAVEYQAKAFQLAHAPSQQRIFI
NVDPHAVDGPHTAKLIRLLSHYERVTVEIIENTCINDAQLANQLFSQFKQADIKVALDDIGAPHSMLCVDLMMNVDYLKF
DRHWLTHITHSEGVQLLIALINFAKQTNKQCILEGIETEAHLAFARDIGVDLVQGFLFKSWFIRPTRSQALCLA
>Mature_234_residues
MINLSSLTLSCEYQPFVDPHTLAIDGYEALARFYLPDGDAVAPNIVFEQLHESTELLAAVEYQAKAFQLAHAPSQQRIFI
NVDPHAVDGPHTAKLIRLLSHYERVTVEIIENTCINDAQLANQLFSQFKQADIKVALDDIGAPHSMLCVDLMMNVDYLKF
DRHWLTHITHSEGVQLLIALINFAKQTNKQCILEGIETEAHLAFARDIGVDLVQGFLFKSWFIRPTRSQALCLA

Specific function: Involved in resistance to phages N4 and lambda [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1788502, Length=226, Percent_Identity=29.646017699115, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI226510982, Length=227, Percent_Identity=27.3127753303965, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI87081743, Length=217, Percent_Identity=26.2672811059908, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 26345; Mature: 26345

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINLSSLTLSCEYQPFVDPHTLAIDGYEALARFYLPDGDAVAPNIVFEQLHESTELLAAV
CCCCCEEEEEECCCCCCCCCEEEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
EYQAKAFQLAHAPSQQRIFINVDPHAVDGPHTAKLIRLLSHYERVTVEIIENTCINDAQL
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ANQLFSQFKQADIKVALDDIGAPHSMLCVDLMMNVDYLKFDRHWLTHITHSEGVQLLIAL
HHHHHHHHHHCCCEEEEHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHH
INFAKQTNKQCILEGIETEAHLAFARDIGVDLVQGFLFKSWFIRPTRSQALCLA
HHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECC
>Mature Secondary Structure
MINLSSLTLSCEYQPFVDPHTLAIDGYEALARFYLPDGDAVAPNIVFEQLHESTELLAAV
CCCCCEEEEEECCCCCCCCCEEEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
EYQAKAFQLAHAPSQQRIFINVDPHAVDGPHTAKLIRLLSHYERVTVEIIENTCINDAQL
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ANQLFSQFKQADIKVALDDIGAPHSMLCVDLMMNVDYLKFDRHWLTHITHSEGVQLLIAL
HHHHHHHHHHCCCEEEEHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHH
INFAKQTNKQCILEGIETEAHLAFARDIGVDLVQGFLFKSWFIRPTRSQALCLA
HHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9079933 [H]