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The map label for this gene is yscC [H]

Identifier: 126174170

GI number: 126174170

Start: 2261794

End: 2263269

Strand: Direct

Name: yscC [H]

Synonym: Sbal_1946

Alternate gene names: 126174170

Gene position: 2261794-2263269 (Clockwise)

Preceding gene: 126174169

Following gene: 126174171

Centisome position: 44.11

GC content: 46.34

Gene sequence:

>1476_bases
ATGAAAAAACTACTCAGTTTACTGTTACTGTGTCAGATGGGCCTAGCTCAGGCTGCACCACTGACAAACATTAAATGGCA
AGGTGAGCCCTTTGTCATGATCAGTCGAGGTACAGCGCTAACCTCAGTCATTCAGGACTTTGCCAGTAATTATGGCGTAC
CAGTCATTGTTAGTAATAAGGTCAACGACAACTATATTGGCCAAATACAACAGCAAGATCCTCAATCCGTTATCCAAGAT
CTCACCCGTCGCTTTGGTTTAGTCTGGTACTACAACAACGACGTCTTATATGTTTACAAAGCCAGTGAAATTAATAGTGA
AGTGCTACCGCTAACCAGCTTATCCGCGGCTAAGGTCGATCACTACCTGCGCAGTGCAGGAGTACTCGATAAGGGGGTCT
GTAGCATTAAATCTATGGCAGGGATCAGTGGCTTACAAGTCACAGGTGTACCCGAATGCATTAACAGCGTCACCAAACTC
ACGGCACAACTCGATGCCAATGCTAAACAAACCACAGAAAACCAAGAAACGGTTAAAGTCTATCCACTGAAATACGCATC
TGCAACCGACTCGGTTTATCAATATCGTAGCCAACCTGTGAGTATTCCAGGATTAGTTACAGTGCTAAAAGAAATGGATC
AAGGTACACAAGTCGCCAATGCCGTGGCGGGTTCTGTGAGTAATATAAGCGGTCCAGTCTTTGCCGCCGATCCTCGCCAA
AACGCCATCATAGTCCGTGGCAGTGCCCGTGATATGGCCACTTATGGCTCTTTGATAAGACAACTCGACACTAAGCCCAC
CATGATTGAAGTGTCTGTATCGATATTCGATGTGGACGCCTCTGACTTTAAACAGCTAGGCATAGATTGGTCGGCGTCAG
CCAAATTAGGCGGTGGTTCAGTGAGCTTCAACAGTGGTGATAGCAGTGACAATTTTTCCACCGTCATAGGTAACACTGGC
AACTTCATGCTGCGCCTCAATGCACTAGAGAAGAACTCTAAGGCCAAAGTACTCTCACGTCCCTCAGTAGTGACGTTAAA
CAATGTGCAAGCCGTACTCGATAAAAATGTGACATTTTACACTAAGTTAGAAGGAGATAAAGTCGCTAAATTAGAATCAG
TGACCACAGGTTCTCTATTACGAGTCACACCAAGATTAATTGATGAAGTGGGCCATCAGGCTGTGATGCTGGATCTCAAT
ATTCAGGATGGTCAACAGAGCCAAGCAGTGAGCCGCAGTGAACCATTACCACAAGTACAAAACTCCGAGATCTCGACCCA
GGCGACGCTGAAATCGGGAGAGAGTCTGTTACTCGGCGGCTTCGTACAAGATAGAGATGAAACGACCCAGAACAAGATCC
CACTACTGGGCGATCTACCACTGCTGGGCGGTTTGTTTAGAAGTACAGATCACCACACTCAAAGCGTGATGCGTCTGTTC
CTGATCAAAGCGGAACCCGTTAACCAAGGAGATTAA

Upstream 100 bases:

>100_bases
CTCAAGGGATTGTCATGCAACTTGCAATAGCGAGGTTTCTCGAAAAGAGCCTGCTTAAACCTGTTGATAGCAATCGAGCC
TCGCTCATCGGGAGGACAGT

Downstream 100 bases:

>100_bases
TATGTCTTCAGGATACAAGCTCTTATGGTTAAACGGTCCATTGCAAGGACGAGAGTTATCTTTGCCTCTTGGCAGCTTAA
GCATAGGACCCGATGGTGAT

Product: YscC/HrcC family type III secretion outer membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MKKLLSLLLLCQMGLAQAAPLTNIKWQGEPFVMISRGTALTSVIQDFASNYGVPVIVSNKVNDNYIGQIQQQDPQSVIQD
LTRRFGLVWYYNNDVLYVYKASEINSEVLPLTSLSAAKVDHYLRSAGVLDKGVCSIKSMAGISGLQVTGVPECINSVTKL
TAQLDANAKQTTENQETVKVYPLKYASATDSVYQYRSQPVSIPGLVTVLKEMDQGTQVANAVAGSVSNISGPVFAADPRQ
NAIIVRGSARDMATYGSLIRQLDTKPTMIEVSVSIFDVDASDFKQLGIDWSASAKLGGGSVSFNSGDSSDNFSTVIGNTG
NFMLRLNALEKNSKAKVLSRPSVVTLNNVQAVLDKNVTFYTKLEGDKVAKLESVTTGSLLRVTPRLIDEVGHQAVMLDLN
IQDGQQSQAVSRSEPLPQVQNSEISTQATLKSGESLLLGGFVQDRDETTQNKIPLLGDLPLLGGLFRSTDHHTQSVMRLF
LIKAEPVNQGD

Sequences:

>Translated_491_residues
MKKLLSLLLLCQMGLAQAAPLTNIKWQGEPFVMISRGTALTSVIQDFASNYGVPVIVSNKVNDNYIGQIQQQDPQSVIQD
LTRRFGLVWYYNNDVLYVYKASEINSEVLPLTSLSAAKVDHYLRSAGVLDKGVCSIKSMAGISGLQVTGVPECINSVTKL
TAQLDANAKQTTENQETVKVYPLKYASATDSVYQYRSQPVSIPGLVTVLKEMDQGTQVANAVAGSVSNISGPVFAADPRQ
NAIIVRGSARDMATYGSLIRQLDTKPTMIEVSVSIFDVDASDFKQLGIDWSASAKLGGGSVSFNSGDSSDNFSTVIGNTG
NFMLRLNALEKNSKAKVLSRPSVVTLNNVQAVLDKNVTFYTKLEGDKVAKLESVTTGSLLRVTPRLIDEVGHQAVMLDLN
IQDGQQSQAVSRSEPLPQVQNSEISTQATLKSGESLLLGGFVQDRDETTQNKIPLLGDLPLLGGLFRSTDHHTQSVMRLF
LIKAEPVNQGD
>Mature_491_residues
MKKLLSLLLLCQMGLAQAAPLTNIKWQGEPFVMISRGTALTSVIQDFASNYGVPVIVSNKVNDNYIGQIQQQDPQSVIQD
LTRRFGLVWYYNNDVLYVYKASEINSEVLPLTSLSAAKVDHYLRSAGVLDKGVCSIKSMAGISGLQVTGVPECINSVTKL
TAQLDANAKQTTENQETVKVYPLKYASATDSVYQYRSQPVSIPGLVTVLKEMDQGTQVANAVAGSVSNISGPVFAADPRQ
NAIIVRGSARDMATYGSLIRQLDTKPTMIEVSVSIFDVDASDFKQLGIDWSASAKLGGGSVSFNSGDSSDNFSTVIGNTG
NFMLRLNALEKNSKAKVLSRPSVVTLNNVQAVLDKNVTFYTKLEGDKVAKLESVTTGSLLRVTPRLIDEVGHQAVMLDLN
IQDGQQSQAVSRSEPLPQVQNSEISTQATLKSGESLLLGGFVQDRDETTQNKIPLLGDLPLLGGLFRSTDHHTQSVMRLF
LIKAEPVNQGD

Specific function: Very likely required for the export process of the yop proteins [H]

COG id: COG1450

COG function: function code NU; Type II secretory pathway, component PulD

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI87082242, Length=376, Percent_Identity=26.3297872340426, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1789793, Length=244, Percent_Identity=25.8196721311475, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005644
- InterPro:   IPR004846
- InterPro:   IPR004845
- InterPro:   IPR003522 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N [H]

EC number: NA

Molecular weight: Translated: 53083; Mature: 53083

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLSLLLLCQMGLAQAAPLTNIKWQGEPFVMISRGTALTSVIQDFASNYGVPVIVSNK
CHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEECCHHHHHHHHHHHHCCCCEEEEECC
VNDNYIGQIQQQDPQSVIQDLTRRFGLVWYYNNDVLYVYKASEINSEVLPLTSLSAAKVD
CCCCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCEEEEEECCCCCCCCCCCCCCHHHHHH
HYLRSAGVLDKGVCSIKSMAGISGLQVTGVPECINSVTKLTAQLDANAKQTTENQETVKV
HHHHHCCCCHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHCCCCHHCCCCCCEEEE
YPLKYASATDSVYQYRSQPVSIPGLVTVLKEMDQGTQVANAVAGSVSNISGPVFAADPRQ
EEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEECCCC
NAIIVRGSARDMATYGSLIRQLDTKPTMIEVSVSIFDVDASDFKQLGIDWSASAKLGGGS
CEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEEEEECCHHHHHHHCCCCCCCCCCCCCE
VSFNSGDSSDNFSTVIGNTGNFMLRLNALEKNSKAKVLSRPSVVTLNNVQAVLDKNVTFY
EEECCCCCCCCCEEEECCCCCEEEEEEECCCCCCCEEECCCCEEEECCHHHHHCCCCEEE
TKLEGDKVAKLESVTTGSLLRVTPRLIDEVGHQAVMLDLNIQDGQQSQAVSRSEPLPQVQ
EEECCCCEEHHHCCCCCCCEEECHHHHHHCCCEEEEEEEECCCCCHHHHHHCCCCCCCCC
NSEISTQATLKSGESLLLGGFVQDRDETTQNKIPLLGDLPLLGGLFRSTDHHTQSVMRLF
CCCCCHHHHHHCCCEEEEECEECCCCCCCCCCCCEEECCHHHHHHHHCCCHHHHHHHHHH
LIKAEPVNQGD
EEECCCCCCCC
>Mature Secondary Structure
MKKLLSLLLLCQMGLAQAAPLTNIKWQGEPFVMISRGTALTSVIQDFASNYGVPVIVSNK
CHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEECCHHHHHHHHHHHHCCCCEEEEECC
VNDNYIGQIQQQDPQSVIQDLTRRFGLVWYYNNDVLYVYKASEINSEVLPLTSLSAAKVD
CCCCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCEEEEEECCCCCCCCCCCCCCHHHHHH
HYLRSAGVLDKGVCSIKSMAGISGLQVTGVPECINSVTKLTAQLDANAKQTTENQETVKV
HHHHHCCCCHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHCCCCHHCCCCCCEEEE
YPLKYASATDSVYQYRSQPVSIPGLVTVLKEMDQGTQVANAVAGSVSNISGPVFAADPRQ
EEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEECCCC
NAIIVRGSARDMATYGSLIRQLDTKPTMIEVSVSIFDVDASDFKQLGIDWSASAKLGGGS
CEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEEEEECCHHHHHHHCCCCCCCCCCCCCE
VSFNSGDSSDNFSTVIGNTGNFMLRLNALEKNSKAKVLSRPSVVTLNNVQAVLDKNVTFY
EEECCCCCCCCCEEEECCCCCEEEEEEECCCCCCCEEECCCCEEEECCHHHHHCCCCEEE
TKLEGDKVAKLESVTTGSLLRVTPRLIDEVGHQAVMLDLNIQDGQQSQAVSRSEPLPQVQ
EEECCCCEEHHHCCCCCCCEEECHHHHHHCCCEEEEEEEECCCCCHHHHHHCCCCCCCCC
NSEISTQATLKSGESLLLGGFVQDRDETTQNKIPLLGDLPLLGGLFRSTDHHTQSVMRLF
CCCCCHHHHHHCCCEEEEECEECCCCCCCCCCCCEEECCHHHHHHHHCCCHHHHHHHHHH
LIKAEPVNQGD
EEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1860816 [H]