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The map label for this gene is nreC [H]

Identifier: 126174167

GI number: 126174167

Start: 2257681

End: 2258325

Strand: Direct

Name: nreC [H]

Synonym: Sbal_1943

Alternate gene names: 126174167

Gene position: 2257681-2258325 (Clockwise)

Preceding gene: 126174166

Following gene: 126174169

Centisome position: 44.03

GC content: 44.65

Gene sequence:

>645_bases
ATGGAATTTAGTCATGGTAAAGTGATCAATATTTTAGTGGTCGATGATCATTCGTTGATTTTCGACGGATTACTGGGTTG
TTTAGCGCCTTATCCAGAGCTTAATCTAATTGGATCGGTTGAAGATGGGCTCGCGGTATACGAGAAATGCCTCAAACTCA
GACCAGATCTGGTTTTTATGGATCTGAAATTACCGGGAATGGGTGGATTTGACGTGATTCGTCAGCTCAGACAACGTTGG
CCAGAGATGATGATTATCATGTTAACGGCGACGGTTGAGGAAAAAAGTGCGCGGGAAGCGCTCGATGTCGGCGCCAATGG
TTATGTGTTAAAATATAGCCCTAAGAGCACGCTGTTAGCGGCAATCAAATGTGTATGTAAGGGTAAAAACTTTATCGATC
CTAGCTTAGATGAGAGACAAATTGCTGCTTTGAGTGGGGTAGTCGATGGGGATATGCCTTTGCTGACCCCCCGCGAGCAA
CAAGTGCTAAAACTCATCTGTGAGGGGCGCCGCAACCGTGATATTGCCGAAGATTTAGTGATTGGTTTAAAAACGGTAGA
GACTCACAGGATGAATTTAATGCGCAAACTTAATGCGCATAACGTCGCCGAGTTAATGCATTGGGTACAAAGGCTTGGAT
TATGA

Upstream 100 bases:

>100_bases
TCTTAAAGGTTAAACGGGTTTTAATACTGTTAAGGGATTTGTTCGTCGATGGTTTTAAAGACTTTTTTATGATCTTGAGT
ATTAGAGTCTAAGGAAATAT

Downstream 100 bases:

>100_bases
AGACGGACGTGGCGCAAGCACAGTTTGGACTGTGCTTGCGCTTTCAGTCTAAGATCAACTTTCAGCATCTAATGTGTGAA
TTAACTTATCGAGTACGCTA

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MEFSHGKVINILVVDDHSLIFDGLLGCLAPYPELNLIGSVEDGLAVYEKCLKLRPDLVFMDLKLPGMGGFDVIRQLRQRW
PEMMIIMLTATVEEKSAREALDVGANGYVLKYSPKSTLLAAIKCVCKGKNFIDPSLDERQIAALSGVVDGDMPLLTPREQ
QVLKLICEGRRNRDIAEDLVIGLKTVETHRMNLMRKLNAHNVAELMHWVQRLGL

Sequences:

>Translated_214_residues
MEFSHGKVINILVVDDHSLIFDGLLGCLAPYPELNLIGSVEDGLAVYEKCLKLRPDLVFMDLKLPGMGGFDVIRQLRQRW
PEMMIIMLTATVEEKSAREALDVGANGYVLKYSPKSTLLAAIKCVCKGKNFIDPSLDERQIAALSGVVDGDMPLLTPREQ
QVLKLICEGRRNRDIAEDLVIGLKTVETHRMNLMRKLNAHNVAELMHWVQRLGL
>Mature_214_residues
MEFSHGKVINILVVDDHSLIFDGLLGCLAPYPELNLIGSVEDGLAVYEKCLKLRPDLVFMDLKLPGMGGFDVIRQLRQRW
PEMMIIMLTATVEEKSAREALDVGANGYVLKYSPKSTLLAAIKCVCKGKNFIDPSLDERQIAALSGVVDGDMPLLTPREQ
QVLKLICEGRRNRDIAEDLVIGLKTVETHRMNLMRKLNAHNVAELMHWVQRLGL

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=211, Percent_Identity=31.2796208530806, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1788712, Length=203, Percent_Identity=29.064039408867, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788521, Length=210, Percent_Identity=31.9047619047619, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1786747, Length=206, Percent_Identity=27.1844660194175, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788546, Length=209, Percent_Identity=28.7081339712919, Blast_Score=90, Evalue=9e-20,
Organism=Escherichia coli, GI1787473, Length=212, Percent_Identity=29.7169811320755, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1790102, Length=198, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788394, Length=167, Percent_Identity=30.5389221556886, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23981; Mature: 23981

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFSHGKVINILVVDDHSLIFDGLLGCLAPYPELNLIGSVEDGLAVYEKCLKLRPDLVFM
CCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHCCCCEEEE
DLKLPGMGGFDVIRQLRQRWPEMMIIMLTATVEEKSAREALDVGANGYVLKYSPKSTLLA
EEECCCCCCHHHHHHHHHHCHHHEEHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHH
AIKCVCKGKNFIDPSLDERQIAALSGVVDGDMPLLTPREQQVLKLICEGRRNRDIAEDLV
HHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHH
IGLKTVETHRMNLMRKLNAHNVAELMHWVQRLGL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MEFSHGKVINILVVDDHSLIFDGLLGCLAPYPELNLIGSVEDGLAVYEKCLKLRPDLVFM
CCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHCCCCEEEE
DLKLPGMGGFDVIRQLRQRWPEMMIIMLTATVEEKSAREALDVGANGYVLKYSPKSTLLA
EEECCCCCCHHHHHHHHHHCHHHEEHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHH
AIKCVCKGKNFIDPSLDERQIAALSGVVDGDMPLLTPREQQVLKLICEGRRNRDIAEDLV
HHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHH
IGLKTVETHRMNLMRKLNAHNVAELMHWVQRLGL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA