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The map label for this gene is minC

Identifier: 126174094

GI number: 126174094

Start: 2167521

End: 2168186

Strand: Reverse

Name: minC

Synonym: Sbal_1868

Alternate gene names: 126174094

Gene position: 2168186-2167521 (Counterclockwise)

Preceding gene: 126174098

Following gene: 126174093

Centisome position: 42.29

GC content: 46.7

Gene sequence:

>666_bases
ATGTCAAAACCTAGCTTAGAGTTAAAAGGCGCTTCTTTTACTCTTTCAGTGCTTCATATTAATAGCAGCGATTTACAAGC
TGTCATGACTGAATTAGACAGTAAGTTGGCACAAGCTCCTCAGTTTTTTCTGGGTGCTCCTTTAGTCGTCAATCTGAGTG
CGATCCAACACGACAGCTTAAATTTAAGTGCGTTAAAGGATCTGCTGATCTCACGTCAATTAGTGATTGTTGGCATAACG
GGCGCGACAACCGTACTCAGTAAACAGGCCAAAGACTTAGGCCTTGCCATAGTCAAAGCCGGAAAACAGAGCAGTACGCC
ACCGCCAGCACCGCGCCAAACTAAGATAGTGAAGCAAAATATTCGTTCAGGCCAACAAGTCTACGCAAAAAATGGTGATT
TAATCATATTTGGTGCGGTAGGCAATGGCGCAGAAGTCATCGCAGATGGTAGCATTCATATCTATGGCGCATTACGAGGG
AAAGCCATGGCAGGCGCGGCGGGCGATACCAGTGCCGTCATCATAGCCCACTCTCTGGAGGCCGAACTCGTTTCAATAGC
AGGGCAATATTGGCTCGCTGAAAATCTACAACAACATAGCTCAGATAAAAGCGGCTGCATTCGCCTAGACGGTGAGTCGC
TTATGGTTGAATCATTGCCCCTCTAA

Upstream 100 bases:

>100_bases
CAAACTTGCCAGTCAATGGGGCACACTATAACATGGTCGCCTAGTAATTTAATTGTAAAATCAGCGAACCGACTGATGAT
TTCTGGAGAATAGTGCCGGG

Downstream 100 bases:

>100_bases
ATGGCAGAACAAAGGATAGAGAGAAACATGGCACAAATTATTGTTGTCACTTCAGGTAAAGGCGGCGTAGGTAAAACCAC
ATCGAGTGCTGCGATTGCGA

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MSKPSLELKGASFTLSVLHINSSDLQAVMTELDSKLAQAPQFFLGAPLVVNLSAIQHDSLNLSALKDLLISRQLVIVGIT
GATTVLSKQAKDLGLAIVKAGKQSSTPPPAPRQTKIVKQNIRSGQQVYAKNGDLIIFGAVGNGAEVIADGSIHIYGALRG
KAMAGAAGDTSAVIIAHSLEAELVSIAGQYWLAENLQQHSSDKSGCIRLDGESLMVESLPL

Sequences:

>Translated_221_residues
MSKPSLELKGASFTLSVLHINSSDLQAVMTELDSKLAQAPQFFLGAPLVVNLSAIQHDSLNLSALKDLLISRQLVIVGIT
GATTVLSKQAKDLGLAIVKAGKQSSTPPPAPRQTKIVKQNIRSGQQVYAKNGDLIIFGAVGNGAEVIADGSIHIYGALRG
KAMAGAAGDTSAVIIAHSLEAELVSIAGQYWLAENLQQHSSDKSGCIRLDGESLMVESLPL
>Mature_220_residues
SKPSLELKGASFTLSVLHINSSDLQAVMTELDSKLAQAPQFFLGAPLVVNLSAIQHDSLNLSALKDLLISRQLVIVGITG
ATTVLSKQAKDLGLAIVKAGKQSSTPPPAPRQTKIVKQNIRSGQQVYAKNGDLIIFGAVGNGAEVIADGSIHIYGALRGK
AMAGAAGDTSAVIIAHSLEAELVSIAGQYWLAENLQQHSSDKSGCIRLDGESLMVESLPL

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

Organism=Escherichia coli, GI1787424, Length=232, Percent_Identity=39.2241379310345, Blast_Score=169, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_SHEB2 (B8E7G0)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002358342.1
- ProteinModelPortal:   B8E7G0
- SMR:   B8E7G0
- GeneID:   7089387
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_2424
- HOGENOM:   HBG399077
- OMA:   KGDTKAR
- ProtClustDB:   PRK04804
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 23120; Mature: 22989

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPSLELKGASFTLSVLHINSSDLQAVMTELDSKLAQAPQFFLGAPLVVNLSAIQHDSL
CCCCCEEECCCEEEEEEEEECCHHHHHHHHHHHHHHHHCCHHHCCCCEEEEEEECCCCCC
NLSALKDLLISRQLVIVGITGATTVLSKQAKDLGLAIVKAGKQSSTPPPAPRQTKIVKQN
CHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCHHHHHHHH
IRSGQQVYAKNGDLIIFGAVGNGAEVIADGSIHIYGALRGKAMAGAAGDTSAVIIAHSLE
HCCCCEEEECCCCEEEEEECCCCCEEEECCCEEEEEEECCCEEECCCCCCEEEEEEECCH
AELVSIAGQYWLAENLQQHSSDKSGCIRLDGESLMVESLPL
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEECCCC
>Mature Secondary Structure 
SKPSLELKGASFTLSVLHINSSDLQAVMTELDSKLAQAPQFFLGAPLVVNLSAIQHDSL
CCCCEEECCCEEEEEEEEECCHHHHHHHHHHHHHHHHCCHHHCCCCEEEEEEECCCCCC
NLSALKDLLISRQLVIVGITGATTVLSKQAKDLGLAIVKAGKQSSTPPPAPRQTKIVKQN
CHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCHHHHHHHH
IRSGQQVYAKNGDLIIFGAVGNGAEVIADGSIHIYGALRGKAMAGAAGDTSAVIIAHSLE
HCCCCEEEECCCCEEEEEECCCCCEEEECCCEEEEEEECCCEEECCCCCCEEEEEEECCH
AELVSIAGQYWLAENLQQHSSDKSGCIRLDGESLMVESLPL
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA