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The map label for this gene is hlyB [H]

Identifier: 126174098

GI number: 126174098

Start: 2170440

End: 2171960

Strand: Reverse

Name: hlyB [H]

Synonym: Sbal_1872

Alternate gene names: 126174098

Gene position: 2171960-2170440 (Counterclockwise)

Preceding gene: 126174105

Following gene: 126174094

Centisome position: 42.36

GC content: 48.32

Gene sequence:

>1521_bases
ATGAAAGAAGTAAAGTTTCGCTGGATAGATCAATATCTTATCCATATGACCTTAAAAACTAAATTCGCTATTCTCTCTAT
CGTTCCCATGCTAATGATTGTTGGACTGGCGATTTTTCTTGATAACCAATCCCAGCAAACCTTAGTGCAAGGACAGCTCA
ACGGTCTTCAAAATGCGTCACAACAAATAAACCAAGTCACAGGCACCTTATATAACAAACTACCAGAGCAAGAACGCCAA
GCTATCCTTAGCCAGCTAAGCCGTGAAATTAAAGGCAATGTCAGCATTATTTCGGTGAATGAAGCCGACAGCAAAGCGCA
ATCCTTAGCCCGCAGCGGTGGCGGCATTGATGAAAGCGGTAAGCAACCTCGAGCTGTGAGTCGCGTTAACGATCAAAACC
TGATCACGATTATTCCCTTCGACAGCAAAGAAATTGATGCCCTGCTCGCCAAAGATAACCTGCTGGTTTACGGCCTGATG
GCGGCGCTTCTGTTCGTTTTGTTTTTATTTAGTTACTACATTTCGACCTTCGTGGGCGGCGCACTTTATACCACAGTGAT
GGCACTAAAACGCGCCGCATCGGGTGACTTAACCGGACGTTTAAACTTCTTCGAAGTAAAGGACGAATTCAGTATCTTAG
CCATCAGTATCGATGCCTTAGTGGAACGTCAGCATCTGTTAGTGAAACAAATCGCCGAGTCGACGACGAAAATCCGCGAG
GTAGTGTCCTCGTTTCGTAGCACAGCGCAGCAAGGTCAATCCTTGGCAGTGAACCAGAGACAACATTTGGACTCCCTAGC
GACGGCGATGGAAGAAATGACCGCCGCAGTGAAGGAAGTCGCCCGCAATGCCGAGCAATCTTCTGCCGAAACCCAAGAGG
CTAATCAACAGGTTAGCGCGGGCGGTAAAGACATTGAGACCACAGTCAAAGCCATCGATGTGTTATCGGATGAAATTTCC
TCAGCCTCGAATGCGGTGGGCGTACTCAATGATAACGCCAGTAAAATTGATGAAGTGGTATCAACCATTAATGCGATTTC
CCAGCAAACCAACCTACTCGCCCTCAACGCGGCGATTGAAGCGGCGCGCGCCGGTGAACAAGGTCGTGGTTTTGCCGTGG
TCGCCGATGAAGTTCGTACCTTAGCGGGCCGCACTCAAGCCGCGACGGTTGAGATCAAAACCATGATCGAATCGCTGCAA
TCTGGCACGCGCAACCTGACACAAGTGATGTCGCGTACTGTGAATCAAGCGAATGAAGGCAAACAACATGTACTGCAAAC
GGGCAAAGACTTAGAGTTTATCGCCCACCACAGTAATAAAGTGTTTGAAATGAGTGTGCTAATCGCCACCTCGGCCGAAG
AACAATCGGCTGTAGCCAACGAGATTGCGACTAACCTGATGGAAATTCGTAACCAGTCCCACGATGTGGAGCAATCGGCG
AACCAGTCGGTTTCAGGTTGTGATGAGCTACAAGCAACAGCAGGGCAACTTGATCAGTTGATGGTGGGATTAAAAATCTA
G

Upstream 100 bases:

>100_bases
TACATTATCGATATAAATCATTACAAAGCAGAAAACTATCAAGTCTATGGCAAACTGACCGATATACATTCGGTTCACAG
CCCATTTTATCGAGGCACTC

Downstream 100 bases:

>100_bases
TCGAGCATTATTTGATAGAATTTAAATTCACTTAACACCCAAAATGCACCAGGGAGCGATAATCGCTCCCTTGTTGTTTT
TTCATTCTGACGGTAACGGT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MKEVKFRWIDQYLIHMTLKTKFAILSIVPMLMIVGLAIFLDNQSQQTLVQGQLNGLQNASQQINQVTGTLYNKLPEQERQ
AILSQLSREIKGNVSIISVNEADSKAQSLARSGGGIDESGKQPRAVSRVNDQNLITIIPFDSKEIDALLAKDNLLVYGLM
AALLFVLFLFSYYISTFVGGALYTTVMALKRAASGDLTGRLNFFEVKDEFSILAISIDALVERQHLLVKQIAESTTKIRE
VVSSFRSTAQQGQSLAVNQRQHLDSLATAMEEMTAAVKEVARNAEQSSAETQEANQQVSAGGKDIETTVKAIDVLSDEIS
SASNAVGVLNDNASKIDEVVSTINAISQQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAGRTQAATVEIKTMIESLQ
SGTRNLTQVMSRTVNQANEGKQHVLQTGKDLEFIAHHSNKVFEMSVLIATSAEEQSAVANEIATNLMEIRNQSHDVEQSA
NQSVSGCDELQATAGQLDQLMVGLKI

Sequences:

>Translated_506_residues
MKEVKFRWIDQYLIHMTLKTKFAILSIVPMLMIVGLAIFLDNQSQQTLVQGQLNGLQNASQQINQVTGTLYNKLPEQERQ
AILSQLSREIKGNVSIISVNEADSKAQSLARSGGGIDESGKQPRAVSRVNDQNLITIIPFDSKEIDALLAKDNLLVYGLM
AALLFVLFLFSYYISTFVGGALYTTVMALKRAASGDLTGRLNFFEVKDEFSILAISIDALVERQHLLVKQIAESTTKIRE
VVSSFRSTAQQGQSLAVNQRQHLDSLATAMEEMTAAVKEVARNAEQSSAETQEANQQVSAGGKDIETTVKAIDVLSDEIS
SASNAVGVLNDNASKIDEVVSTINAISQQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAGRTQAATVEIKTMIESLQ
SGTRNLTQVMSRTVNQANEGKQHVLQTGKDLEFIAHHSNKVFEMSVLIATSAEEQSAVANEIATNLMEIRNQSHDVEQSA
NQSVSGCDELQATAGQLDQLMVGLKI
>Mature_506_residues
MKEVKFRWIDQYLIHMTLKTKFAILSIVPMLMIVGLAIFLDNQSQQTLVQGQLNGLQNASQQINQVTGTLYNKLPEQERQ
AILSQLSREIKGNVSIISVNEADSKAQSLARSGGGIDESGKQPRAVSRVNDQNLITIIPFDSKEIDALLAKDNLLVYGLM
AALLFVLFLFSYYISTFVGGALYTTVMALKRAASGDLTGRLNFFEVKDEFSILAISIDALVERQHLLVKQIAESTTKIRE
VVSSFRSTAQQGQSLAVNQRQHLDSLATAMEEMTAAVKEVARNAEQSSAETQEANQQVSAGGKDIETTVKAIDVLSDEIS
SASNAVGVLNDNASKIDEVVSTINAISQQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAGRTQAATVEIKTMIESLQ
SGTRNLTQVMSRTVNQANEGKQHVLQTGKDLEFIAHHSNKVFEMSVLIATSAEEQSAVANEIATNLMEIRNQSHDVEQSA
NQSVSGCDELQATAGQLDQLMVGLKI

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=320, Percent_Identity=30.9375, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI2367378, Length=398, Percent_Identity=28.643216080402, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1787690, Length=194, Percent_Identity=38.659793814433, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1788194, Length=208, Percent_Identity=37.5, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1789453, Length=187, Percent_Identity=33.1550802139037, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 54916; Mature: 54916

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEVKFRWIDQYLIHMTLKTKFAILSIVPMLMIVGLAIFLDNQSQQTLVQGQLNGLQNAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QQINQVTGTLYNKLPEQERQAILSQLSREIKGNVSIISVNEADSKAQSLARSGGGIDESG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCC
KQPRAVSRVNDQNLITIIPFDSKEIDALLAKDNLLVYGLMAALLFVLFLFSYYISTFVGG
CCCCHHHHCCCCCEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALYTTVMALKRAASGDLTGRLNFFEVKDEFSILAISIDALVERQHLLVKQIAESTTKIRE
HHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
VVSSFRSTAQQGQSLAVNQRQHLDSLATAMEEMTAAVKEVARNAEQSSAETQEANQQVSA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGKDIETTVKAIDVLSDEISSASNAVGVLNDNASKIDEVVSTINAISQQTNLLALNAAIE
CCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCEEHHHHHH
AARAGEQGRGFAVVADEVRTLAGRTQAATVEIKTMIESLQSGTRNLTQVMSRTVNQANEG
HHHCCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCC
KQHVLQTGKDLEFIAHHSNKVFEMSVLIATSAEEQSAVANEIATNLMEIRNQSHDVEQSA
HHHHHHCCCCHHHHHHCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHH
NQSVSGCDELQATAGQLDQLMVGLKI
CCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKEVKFRWIDQYLIHMTLKTKFAILSIVPMLMIVGLAIFLDNQSQQTLVQGQLNGLQNAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QQINQVTGTLYNKLPEQERQAILSQLSREIKGNVSIISVNEADSKAQSLARSGGGIDESG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCC
KQPRAVSRVNDQNLITIIPFDSKEIDALLAKDNLLVYGLMAALLFVLFLFSYYISTFVGG
CCCCHHHHCCCCCEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALYTTVMALKRAASGDLTGRLNFFEVKDEFSILAISIDALVERQHLLVKQIAESTTKIRE
HHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
VVSSFRSTAQQGQSLAVNQRQHLDSLATAMEEMTAAVKEVARNAEQSSAETQEANQQVSA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGKDIETTVKAIDVLSDEISSASNAVGVLNDNASKIDEVVSTINAISQQTNLLALNAAIE
CCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCEEHHHHHH
AARAGEQGRGFAVVADEVRTLAGRTQAATVEIKTMIESLQSGTRNLTQVMSRTVNQANEG
HHHCCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCC
KQHVLQTGKDLEFIAHHSNKVFEMSVLIATSAEEQSAVANEIATNLMEIRNQSHDVEQSA
HHHHHHCCCCHHHHHHCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHH
NQSVSGCDELQATAGQLDQLMVGLKI
CCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]