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The map label for this gene is bioD [H]

Identifier: 126173988

GI number: 126173988

Start: 2051875

End: 2052615

Strand: Direct

Name: bioD [H]

Synonym: Sbal_1761

Alternate gene names: 126173988

Gene position: 2051875-2052615 (Clockwise)

Preceding gene: 126173987

Following gene: 126173994

Centisome position: 40.02

GC content: 50.07

Gene sequence:

>741_bases
ATGTTTTTTGTAACAGGTACAGATACCGACAGTGGTAAAACCTTAGTCTCATCGGCGCTGTTAACCGCGGTGAACCGTTT
GGGCGCGATCGCCAGTGCTGACTCGGCTGTGAGTATTTTGGCGTCTAACACGCTGTCGACCTTAGGTGTTAAGCCCATCG
CCTCGGGCTGCGCACAAACCTCCGAAGGCTTGCGTAATGCCGATGCACTGCAGTTGATGACTTCATCGTCGCTGAAACTT
ACTTATCCTGTCATTAATCCTTTTACCTTTGAACCTGCGATTGCGCCGCATATTGCTGCCGCCCAAGTGGGCGTGAGTTT
AGCACCTGAAGCCATTATCGAAAGTTTGGATTTAGCGGCATTTGCTCAAGCGGATTTTAGCTTGATTGAGGGCGCGGGTG
GCTGGCGTTTACCCTTAGGCGAGGGCCGATATTTATCGGAAGTGGTACAGAGATTAGAACTGCCAGTGATACTCGTGGTG
GGCATGAAGCTCGGTTGCTTAAATCACGCACTGCTCACTCAAGAGGCAATACTGGCCGATGGGCTTAAGATTGCAGGTTG
GGTCGCCAATTGTGTCGACCCAAATATGAGTATGTTTGAGGAGAATCTGACGAGCCTTAAAGAGATGATGTCAGCGCCTT
TCCTCGGCTGTGTGCCTTTTCTTGATGATCCCAGTGCTGAAAATGCCGCCGATTATCTTAATACTTCGCCGCTTTTTCAA
AGCGCAGAGGCTAATGCATAG

Upstream 100 bases:

>100_bases
TGTGGACTTGTGGATTTAAAGGTCTATAGGTTTGCGTTTTAGCTTTATGGAGAGTGCACTTCACAAAAGTGCACTCAATA
GCGACAGATAAGGATCTAAT

Downstream 100 bases:

>100_bases
GCAGTGCCTAACTAATGTTTAGCCGCTGAGCGGCTTAATGAGCGGTACTGCTAATGTGTTTAGACAAAAAAATAAGCCTC
ACATTGCGTTGAGGCTTATT

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MFFVTGTDTDSGKTLVSSALLTAVNRLGAIASADSAVSILASNTLSTLGVKPIASGCAQTSEGLRNADALQLMTSSSLKL
TYPVINPFTFEPAIAPHIAAAQVGVSLAPEAIIESLDLAAFAQADFSLIEGAGGWRLPLGEGRYLSEVVQRLELPVILVV
GMKLGCLNHALLTQEAILADGLKIAGWVANCVDPNMSMFEENLTSLKEMMSAPFLGCVPFLDDPSAENAADYLNTSPLFQ
SAEANA

Sequences:

>Translated_246_residues
MFFVTGTDTDSGKTLVSSALLTAVNRLGAIASADSAVSILASNTLSTLGVKPIASGCAQTSEGLRNADALQLMTSSSLKL
TYPVINPFTFEPAIAPHIAAAQVGVSLAPEAIIESLDLAAFAQADFSLIEGAGGWRLPLGEGRYLSEVVQRLELPVILVV
GMKLGCLNHALLTQEAILADGLKIAGWVANCVDPNMSMFEENLTSLKEMMSAPFLGCVPFLDDPSAENAADYLNTSPLFQ
SAEANA
>Mature_246_residues
MFFVTGTDTDSGKTLVSSALLTAVNRLGAIASADSAVSILASNTLSTLGVKPIASGCAQTSEGLRNADALQLMTSSSLKL
TYPVINPFTFEPAIAPHIAAAQVGVSLAPEAIIESLDLAAFAQADFSLIEGAGGWRLPLGEGRYLSEVVQRLELPVILVV
GMKLGCLNHALLTQEAILADGLKIAGWVANCVDPNMSMFEENLTSLKEMMSAPFLGCVPFLDDPSAENAADYLNTSPLFQ
SAEANA

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=236, Percent_Identity=46.1864406779661, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI87081944, Length=233, Percent_Identity=36.480686695279, Blast_Score=153, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 25663; Mature: 25663

Theoretical pI: Translated: 4.06; Mature: 4.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFVTGTDTDSGKTLVSSALLTAVNRLGAIASADSAVSILASNTLSTLGVKPIASGCAQT
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
SEGLRNADALQLMTSSSLKLTYPVINPFTFEPAIAPHIAAAQVGVSLAPEAIIESLDLAA
HHHHCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHH
FAQADFSLIEGAGGWRLPLGEGRYLSEVVQRLELPVILVVGMKLGCLNHALLTQEAILAD
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHC
GLKIAGWVANCVDPNMSMFEENLTSLKEMMSAPFLGCVPFLDDPSAENAADYLNTSPLFQ
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHCCCCHHHC
SAEANA
CCCCCC
>Mature Secondary Structure
MFFVTGTDTDSGKTLVSSALLTAVNRLGAIASADSAVSILASNTLSTLGVKPIASGCAQT
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
SEGLRNADALQLMTSSSLKLTYPVINPFTFEPAIAPHIAAAQVGVSLAPEAIIESLDLAA
HHHHCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHH
FAQADFSLIEGAGGWRLPLGEGRYLSEVVQRLELPVILVVGMKLGCLNHALLTQEAILAD
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHC
GLKIAGWVANCVDPNMSMFEENLTSLKEMMSAPFLGCVPFLDDPSAENAADYLNTSPLFQ
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHCCCCHHHC
SAEANA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA