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The map label for this gene is glnS [H]

Identifier: 126173830

GI number: 126173830

Start: 1864356

End: 1866026

Strand: Direct

Name: glnS [H]

Synonym: Sbal_1596

Alternate gene names: 126173830

Gene position: 1864356-1866026 (Clockwise)

Preceding gene: 126173829

Following gene: 126173832

Centisome position: 36.36

GC content: 44.23

Gene sequence:

>1671_bases
ATGAGTCATGTGGACACTGAAGTACGTCCGAGTAACTTTATTCGTAATATCATAGATGAAGATTTACAAAGCGGTAAGCA
CACGAGTGTACAGACTCGTTTCCCGCCGGAACCGAATGGCTATCTTCATATTGGTCATGCTAAATCTATCTGCTTAAATT
TTGGGATAGCGCGAGACTATAACGGTCTGTGTAATTTACGTTTTGACGATACTAATCCTGAAAAAGAAGACATTGATTAT
GTGAATTCTATTCAGGCGGATGTGCGTTGGCTTGGATTCCAGTGGGATGGCGACGTGCGCTATTCATCAAACTATTTTGA
TCAGTTACACCAATATGCGGTTGAACTGATCAATAAAGGTTTGGCTTATGTGTGTTTCTTGAATGCTGATGAAACCCGCG
AATACCGTGGCACGTTAAAAGAGCCAGGTAAAAACAGTCCTTTCCGCGACACATCAGTCGAAGAGAACCTCGCCTTATTC
GCTAAGATGCGCGACGGTGGTTTTAAAGAAGGTGAGTGTGCGCTGCGTGCAAAAATTGATATGGCGTCGCCATTCATGTG
TATGCGCGATCCTATCATCTACCGTATTCGTTTTGCCCATCACCACCAAACGGGTGACAAGTGGTGCATTTACCCAATGT
ACGACTTTACCCACTGTATTTCTGATGCGTTAGAACATATTACCCACTCTTTATGTACTTTAGAGTTCCAAGACAACCGT
CGTTTATACGACTGGGTGTTGGATAATTTGAATGATTTTCAAGCGCCGAATCGTACTCGTCAATACGAGTTTTCACGCTT
AAATCTCGAATATACCTTGATGTCTAAGCGTAAGCTAAACGACCTTGTGACTCGTAAATTAGTGTCAGGTTGGGACGACC
CACGTATGCCAACGATTGCTGGCTTACGTCGCCGTGGTTACACGCCTGCGTCAATTCGCGAGTTCTGCCAACGTATCGGC
GTGACTAAGCAAGAGAATATGATTGAAGTCGGCATGTTAGATGCGTGTATTCGTGAAGAATTGAACGAACATGCACCGCG
TGCGATGGCTGTATTACGTCCATTGAAAGTGATCATCGAAAACTATGCTGAAGGTGAACTTGAGTACATTCAAGCGGCCG
CTCATCCAAATGATGAGAGCATGGGGACGCGTGAATTAGCCTTTGGCCGTGAAATATTGATTGATGTGGCTGACTTTAAA
GAAGAAGCCAACAAGCAATACAAACGCTTAGTTACAGGTAAGGAAGTGCGTTTACGAAATGCCTATGTGATTAAAGCTGA
ACGTTGTGACAAAGACAGCGAAGGCAATATCACGACGGTTTACTGCACTTATGATCCTGAAACCTTAGGTAAAAACCCTG
CTGATGGCCGTAAAGTCAAAGGCGTGATCCATTGGGTTGAGGCATCTACTGCCAAGCCTGCTGAATTCCGCTTATATCAG
CGTTTATTTACCGATCCTAACCCAGCAGCGGCTGAGACTGTGGACGAAGTATTAAACCCTGAATCATTAGTGGTTGTGCA
CGGTTTTGCTGAAGCAAGCCTAGTAAATGCACCAGCAGAAAAAGCTTATCAGTTTGAGCGTGAAGGTTATTTCTGTGCTG
ACAGCAAAGATTCATCAGTTGATAAACTCGTGTTTAACTTAACCGTAGCGCTGCGTGATTCTTTCGAGTGA

Upstream 100 bases:

>100_bases
CAAAAACCATAGTTTTTAGCACTAGGCATTGTAACTAGTAGTGATCTGTAGGATCATGCTGGTTTTCTTAAAATTGCCAT
TGTTCGCAAAGAGGAATTCC

Downstream 100 bases:

>100_bases
TTTGATAGAATTGGTTTGATTGAATTTGTTTGATGGAATGAGTCAAACAGTTAAACTCAATTAAACTAAGTTGAATTAAG
CTAGGTTGTTCTGATCATTA

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 556; Mature: 555

Protein sequence:

>556_residues
MSHVDTEVRPSNFIRNIIDEDLQSGKHTSVQTRFPPEPNGYLHIGHAKSICLNFGIARDYNGLCNLRFDDTNPEKEDIDY
VNSIQADVRWLGFQWDGDVRYSSNYFDQLHQYAVELINKGLAYVCFLNADETREYRGTLKEPGKNSPFRDTSVEENLALF
AKMRDGGFKEGECALRAKIDMASPFMCMRDPIIYRIRFAHHHQTGDKWCIYPMYDFTHCISDALEHITHSLCTLEFQDNR
RLYDWVLDNLNDFQAPNRTRQYEFSRLNLEYTLMSKRKLNDLVTRKLVSGWDDPRMPTIAGLRRRGYTPASIREFCQRIG
VTKQENMIEVGMLDACIREELNEHAPRAMAVLRPLKVIIENYAEGELEYIQAAAHPNDESMGTRELAFGREILIDVADFK
EEANKQYKRLVTGKEVRLRNAYVIKAERCDKDSEGNITTVYCTYDPETLGKNPADGRKVKGVIHWVEASTAKPAEFRLYQ
RLFTDPNPAAAETVDEVLNPESLVVVHGFAEASLVNAPAEKAYQFEREGYFCADSKDSSVDKLVFNLTVALRDSFE

Sequences:

>Translated_556_residues
MSHVDTEVRPSNFIRNIIDEDLQSGKHTSVQTRFPPEPNGYLHIGHAKSICLNFGIARDYNGLCNLRFDDTNPEKEDIDY
VNSIQADVRWLGFQWDGDVRYSSNYFDQLHQYAVELINKGLAYVCFLNADETREYRGTLKEPGKNSPFRDTSVEENLALF
AKMRDGGFKEGECALRAKIDMASPFMCMRDPIIYRIRFAHHHQTGDKWCIYPMYDFTHCISDALEHITHSLCTLEFQDNR
RLYDWVLDNLNDFQAPNRTRQYEFSRLNLEYTLMSKRKLNDLVTRKLVSGWDDPRMPTIAGLRRRGYTPASIREFCQRIG
VTKQENMIEVGMLDACIREELNEHAPRAMAVLRPLKVIIENYAEGELEYIQAAAHPNDESMGTRELAFGREILIDVADFK
EEANKQYKRLVTGKEVRLRNAYVIKAERCDKDSEGNITTVYCTYDPETLGKNPADGRKVKGVIHWVEASTAKPAEFRLYQ
RLFTDPNPAAAETVDEVLNPESLVVVHGFAEASLVNAPAEKAYQFEREGYFCADSKDSSVDKLVFNLTVALRDSFE
>Mature_555_residues
SHVDTEVRPSNFIRNIIDEDLQSGKHTSVQTRFPPEPNGYLHIGHAKSICLNFGIARDYNGLCNLRFDDTNPEKEDIDYV
NSIQADVRWLGFQWDGDVRYSSNYFDQLHQYAVELINKGLAYVCFLNADETREYRGTLKEPGKNSPFRDTSVEENLALFA
KMRDGGFKEGECALRAKIDMASPFMCMRDPIIYRIRFAHHHQTGDKWCIYPMYDFTHCISDALEHITHSLCTLEFQDNRR
LYDWVLDNLNDFQAPNRTRQYEFSRLNLEYTLMSKRKLNDLVTRKLVSGWDDPRMPTIAGLRRRGYTPASIREFCQRIGV
TKQENMIEVGMLDACIREELNEHAPRAMAVLRPLKVIIENYAEGELEYIQAAAHPNDESMGTRELAFGREILIDVADFKE
EANKQYKRLVTGKEVRLRNAYVIKAERCDKDSEGNITTVYCTYDPETLGKNPADGRKVKGVIHWVEASTAKPAEFRLYQR
LFTDPNPAAAETVDEVLNPESLVVVHGFAEASLVNAPAEKAYQFEREGYFCADSKDSSVDKLVFNLTVALRDSFE

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=530, Percent_Identity=46.6037735849057, Blast_Score=437, Evalue=1e-122,
Organism=Homo sapiens, GI62241042, Length=516, Percent_Identity=32.3643410852713, Blast_Score=257, Evalue=2e-68,
Organism=Escherichia coli, GI1786895, Length=551, Percent_Identity=73.502722323049, Blast_Score=853, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=107, Percent_Identity=29.9065420560748, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17543332, Length=536, Percent_Identity=43.0970149253731, Blast_Score=417, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17511007, Length=527, Percent_Identity=31.3092979127135, Blast_Score=224, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6324742, Length=567, Percent_Identity=39.8589065255732, Blast_Score=381, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6321192, Length=520, Percent_Identity=33.8461538461538, Blast_Score=278, Evalue=1e-75,
Organism=Drosophila melanogaster, GI17864488, Length=533, Percent_Identity=42.4015009380863, Blast_Score=414, Evalue=1e-116,
Organism=Drosophila melanogaster, GI24649466, Length=421, Percent_Identity=39.667458432304, Blast_Score=271, Evalue=7e-73,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 63926; Mature: 63794

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHVDTEVRPSNFIRNIIDEDLQSGKHTSVQTRFPPEPNGYLHIGHAKSICLNFGIARDY
CCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCHHHHHHCCCCCCCC
NGLCNLRFDDTNPEKEDIDYVNSIQADVRWLGFQWDGDVRYSSNYFDQLHQYAVELINKG
CCEEEEEECCCCCCHHHHHHHHHHHHCEEEEEEEECCCEEECHHHHHHHHHHHHHHHHCC
LAYVCFLNADETREYRGTLKEPGKNSPFRDTSVEENLALFAKMRDGGFKEGECALRAKID
CEEEEEECCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHEEEEECCCCCCCCCEEEEEEEC
MASPFMCMRDPIIYRIRFAHHHQTGDKWCIYPMYDFTHCISDALEHITHSLCTLEFQDNR
CCCCCHHHCCCEEEEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEEEECCCC
RLYDWVLDNLNDFQAPNRTRQYEFSRLNLEYTLMSKRKLNDLVTRKLVSGWDDPRMPTIA
CHHHHHHCCCHHCCCCCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHH
GLRRRGYTPASIREFCQRIGVTKQENMIEVGMLDACIREELNEHAPRAMAVLRPLKVIIE
HHHHCCCCCHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
NYAEGELEYIQAAAHPNDESMGTRELAFGREILIDVADFKEEANKQYKRLVTGKEVRLRN
HCCCCHHHHHHHHCCCCCCCCCCHHHHCCHHHEEEHHHHHHHHHHHHHHHHCCCEEEECC
AYVIKAERCDKDSEGNITTVYCTYDPETLGKNPADGRKVKGVIHWVEASTAKPAEFRLYQ
EEEEEEHHCCCCCCCCEEEEEEEECHHHCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHH
RLFTDPNPAAAETVDEVLNPESLVVVHGFAEASLVNAPAEKAYQFEREGYFCADSKDSSV
HHHCCCCCHHHHHHHHHCCCCCEEEEECCCHHHHHCCCHHHHHHHHCCCEEEECCCCCCH
DKLVFNLTVALRDSFE
HHHHHHEEEEECCCCC
>Mature Secondary Structure 
SHVDTEVRPSNFIRNIIDEDLQSGKHTSVQTRFPPEPNGYLHIGHAKSICLNFGIARDY
CCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCHHHHHHCCCCCCCC
NGLCNLRFDDTNPEKEDIDYVNSIQADVRWLGFQWDGDVRYSSNYFDQLHQYAVELINKG
CCEEEEEECCCCCCHHHHHHHHHHHHCEEEEEEEECCCEEECHHHHHHHHHHHHHHHHCC
LAYVCFLNADETREYRGTLKEPGKNSPFRDTSVEENLALFAKMRDGGFKEGECALRAKID
CEEEEEECCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHEEEEECCCCCCCCCEEEEEEEC
MASPFMCMRDPIIYRIRFAHHHQTGDKWCIYPMYDFTHCISDALEHITHSLCTLEFQDNR
CCCCCHHHCCCEEEEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEEEECCCC
RLYDWVLDNLNDFQAPNRTRQYEFSRLNLEYTLMSKRKLNDLVTRKLVSGWDDPRMPTIA
CHHHHHHCCCHHCCCCCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHH
GLRRRGYTPASIREFCQRIGVTKQENMIEVGMLDACIREELNEHAPRAMAVLRPLKVIIE
HHHHCCCCCHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
NYAEGELEYIQAAAHPNDESMGTRELAFGREILIDVADFKEEANKQYKRLVTGKEVRLRN
HCCCCHHHHHHHHCCCCCCCCCCHHHHCCHHHEEEHHHHHHHHHHHHHHHHCCCEEEECC
AYVIKAERCDKDSEGNITTVYCTYDPETLGKNPADGRKVKGVIHWVEASTAKPAEFRLYQ
EEEEEEHHCCCCCCCCEEEEEEEECHHHCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHH
RLFTDPNPAAAETVDEVLNPESLVVVHGFAEASLVNAPAEKAYQFEREGYFCADSKDSSV
HHHCCCCCHHHHHHHHHCCCCCEEEEECCCHHHHHCCCHHHHHHHHCCCEEEECCCCCCH
DKLVFNLTVALRDSFE
HHHHHHEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]