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The map label for this gene is cysQ [H]

Identifier: 126173712

GI number: 126173712

Start: 1714688

End: 1715494

Strand: Direct

Name: cysQ [H]

Synonym: Sbal_1474

Alternate gene names: 126173712

Gene position: 1714688-1715494 (Clockwise)

Preceding gene: 126173711

Following gene: 126173713

Centisome position: 33.44

GC content: 50.19

Gene sequence:

>807_bases
GTGACAAACAAGACGACAATAGCACAGACATTGACCAAACAAGATCTACTGCAAGTGGTCGCGATTGCCAAAACGGCGGG
CGATGCCATTATGACGGTTTATGGTCAAGATGACTTTTCGGTGAGCCACAAGGGCGACGATAGTCCCGTGACGGCCGCCG
ATTTAGCCGCGCACCACGTGATAGTGGCGGCATTGGCGCAGCAGTTTGTCGGTATTCCTATTATGTCTGAGGAAGCGGCG
GATATTGCCTGGGATGAGCGTCGTCAATGGCAAACCTATTGGTTAATTGACCCTTTAGATGGCACTAAGGAATTTATTAA
GCGCAATGGCGAGTTTACCGTCAATATTGCGCTTATCCATCAAGGGGTTGCTATTGCAGGTGTGGTTTATGCGCCTGTGC
TCGATACCTATTATTACGGCGCTAAGCATTTAGGTGCATGGCGTCAACAAACGGGTCAAGAAAGTCCCTTATTGGGCGCT
AAAGTGCCACGTGCGATGCCGATGATTGTTGGCAGCCGCTCGCACTTGAGCCCAGGTTTAGCGCAATATTTACAACAGTT
TGGCGAGCATGACATCTTAAGCGTGGGTAGCTCGCTTAAGTTTTGTATGTTGGCAGAAGGCAGTGCCGATCTGTACCCCA
GACTGGGCCCTACCAGCGAGTGGGACACTGCGGCGGCGCAAGCTGTGCTCGAAAGTGCAGGCGGCACAGTTGTCTGTTAT
GAGTCAGGTGAACCATTAACTTATAATCAAAAACCTGACATTTTAAACCCTTACTTTATTGCCACAGCCCCAGGCTGGGT
GAAATAA

Upstream 100 bases:

>100_bases
TCTTAGTCTATTTTGCTTGATGTATGATGAATTTGTTCTAAATTCCCCTTGGATGACAATGGCATAATGCCAAGATATTT
AATGCATTAAGGACGTTTCA

Downstream 100 bases:

>100_bases
CGACCGCCTAGCATCGATATTCGTTGATGAATGGGCGGGCTAAACACTGGAGTAGTAATTCATGATGCGCATGGGCGTCG
ATTTAGGCGGAACAAAAATA

Product: 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MTNKTTIAQTLTKQDLLQVVAIAKTAGDAIMTVYGQDDFSVSHKGDDSPVTAADLAAHHVIVAALAQQFVGIPIMSEEAA
DIAWDERRQWQTYWLIDPLDGTKEFIKRNGEFTVNIALIHQGVAIAGVVYAPVLDTYYYGAKHLGAWRQQTGQESPLLGA
KVPRAMPMIVGSRSHLSPGLAQYLQQFGEHDILSVGSSLKFCMLAEGSADLYPRLGPTSEWDTAAAQAVLESAGGTVVCY
ESGEPLTYNQKPDILNPYFIATAPGWVK

Sequences:

>Translated_268_residues
MTNKTTIAQTLTKQDLLQVVAIAKTAGDAIMTVYGQDDFSVSHKGDDSPVTAADLAAHHVIVAALAQQFVGIPIMSEEAA
DIAWDERRQWQTYWLIDPLDGTKEFIKRNGEFTVNIALIHQGVAIAGVVYAPVLDTYYYGAKHLGAWRQQTGQESPLLGA
KVPRAMPMIVGSRSHLSPGLAQYLQQFGEHDILSVGSSLKFCMLAEGSADLYPRLGPTSEWDTAAAQAVLESAGGTVVCY
ESGEPLTYNQKPDILNPYFIATAPGWVK
>Mature_267_residues
TNKTTIAQTLTKQDLLQVVAIAKTAGDAIMTVYGQDDFSVSHKGDDSPVTAADLAAHHVIVAALAQQFVGIPIMSEEAAD
IAWDERRQWQTYWLIDPLDGTKEFIKRNGEFTVNIALIHQGVAIAGVVYAPVLDTYYYGAKHLGAWRQQTGQESPLLGAK
VPRAMPMIVGSRSHLSPGLAQYLQQFGEHDILSVGSSLKFCMLAEGSADLYPRLGPTSEWDTAAAQAVLESAGGTVVCYE
SGEPLTYNQKPDILNPYFIATAPGWVK

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=237, Percent_Identity=28.6919831223629, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI116812595, Length=264, Percent_Identity=28.030303030303, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1790659, Length=246, Percent_Identity=52.8455284552846, Blast_Score=223, Evalue=9e-60,
Organism=Escherichia coli, GI1788882, Length=231, Percent_Identity=29.004329004329, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71995905, Length=284, Percent_Identity=26.7605633802817, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71995897, Length=284, Percent_Identity=26.7605633802817, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17537869, Length=288, Percent_Identity=25.6944444444444, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24651149, Length=270, Percent_Identity=28.1481481481481, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 29039; Mature: 28908

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNKTTIAQTLTKQDLLQVVAIAKTAGDAIMTVYGQDDFSVSHKGDDSPVTAADLAAHHV
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEECCCCCCCCCHHHHHHHHHH
IVAALAQQFVGIPIMSEEAADIAWDERRQWQTYWLIDPLDGTKEFIKRNGEFTVNIALIH
HHHHHHHHHHCCCCCCCCCHHCCHHHCCCCEEEEEEECCCCHHHHHHCCCCEEEEEEEEE
QGVAIAGVVYAPVLDTYYYGAKHLGAWRQQTGQESPLLGAKVPRAMPMIVGSRSHLSPGL
CCHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCHHHHEECCCCCCCHHH
AQYLQQFGEHDILSVGSSLKFCMLAEGSADLYPRLGPTSEWDTAAAQAVLESAGGTVVCY
HHHHHHHCCCCHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEE
ESGEPLTYNQKPDILNPYFIATAPGWVK
ECCCCCEECCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure 
TNKTTIAQTLTKQDLLQVVAIAKTAGDAIMTVYGQDDFSVSHKGDDSPVTAADLAAHHV
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEECCCCCCCCCHHHHHHHHHH
IVAALAQQFVGIPIMSEEAADIAWDERRQWQTYWLIDPLDGTKEFIKRNGEFTVNIALIH
HHHHHHHHHHCCCCCCCCCHHCCHHHCCCCEEEEEEECCCCHHHHHHCCCCEEEEEEEEE
QGVAIAGVVYAPVLDTYYYGAKHLGAWRQQTGQESPLLGAKVPRAMPMIVGSRSHLSPGL
CCHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCHHHHEECCCCCCCHHH
AQYLQQFGEHDILSVGSSLKFCMLAEGSADLYPRLGPTSEWDTAAAQAVLESAGGTVVCY
HHHHHHHCCCCHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEE
ESGEPLTYNQKPDILNPYFIATAPGWVK
ECCCCCEECCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]