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The map label for this gene is rlmM

Identifier: 126173605

GI number: 126173605

Start: 1566404

End: 1567489

Strand: Direct

Name: rlmM

Synonym: Sbal_1367

Alternate gene names: 126173605

Gene position: 1566404-1567489 (Clockwise)

Preceding gene: 126173604

Following gene: 126173607

Centisome position: 30.55

GC content: 48.07

Gene sequence:

>1086_bases
ATGAAAAACCTATTTTTATTTTGCCGCGCAGGCTTTGAAAAAGAATGCGCTGCAGAAATCCAACAGCGAGCCGGTGAGCT
CAATGTGGGTGGCTTTGTTAAGGCCAACAATAACGACGCCTATGTCGTATACCAATGTTTTGAAGATGACGCCGCAGATA
CGTTAGTGAAACAACTGCCTTTAGATTCGCTCATTTTCGCTCGCCAGATGTTTGCTGCCAGCGACTTGTTAGTCGACTTG
CCTGAAAACGACAGAATTAGCCCAATCGTGGCGGCACTCAGTGACGTCAGCAAAGCGGGTGAAGTGCGGGTTGAAACGCC
AGATACTAACGAAGCGAAAGAGCTCTCGGCTTTTTGCCGTAAGTTCACTGTGCCTTTACGCCAGCATTTGAAAAAATCTG
GCAGTTTGCTCGCGCAGGAAAATCCAAAACGTCCGATTATCCACGTGTGTTTTATCGGACCCGGCCGTGCCTATGTGGGT
TATTCCTACAGCAATAACAGCTCGCCACACTTTATGGGTATTCCACGTCTGAAAATGGCGGCGGATGCTCCGAGTCGTTC
TAGCCTGAAACTCGATGAAGCCTTTGGCCAATTCGTGCCTAAGGAAGAGCAAGAAGAGCGTATTCGCAGTGGTATGAACT
CAGTGGATTTGGGCGCTTGCCCAGGTGGCTGGACTTATCAACTGGTGCGTCGCGGCATGTTTGTGTCGGCTGTTGATAAT
GGTCCCATGGATGAGAAACTCATGGAAACGGGCCAAGTGAAGCATTACCGTGAAGACGGTTTCCGTTTCGAGCCACAGCG
CAAAAATATCTATTGGCTAGTGTGCGACATGGTTGAGAAACCAGCGCGTGTTGCCGAACTGATTGAAGCTTGGGCGATTA
ACGGTTGGTTTAAGGAAGCGATTTTCAACCTTAAATTACCGATGAAGAGCCGCTATAAAGAAGTCACTGCCATTCTTGAG
ACCATGCAGACCATTCTTAAAGAGAATGGCGTGACCGATTTTAAAGTGCAGTGTAAGCATCTTTATCACGATCGTGATGA
AGTGACAGTGCATTTATGGCTGCGTCCTAATACCGCGTGGAATTAA

Upstream 100 bases:

>100_bases
CCGCTGTAGGCAAATAGGGCATTTGTGGATTGAAATTGGTATACTGACGCCCAAATCGATAGTCAGCCAATGCTTTGGCT
TGGATTTCTCAGGGATCCCC

Downstream 100 bases:

>100_bases
TTCCTGCGATAACTCTGCAGTGATATTGCCGTCGTTACTCGCGTACGTTACTTAGGTACGCTAATACGGTAATCGTCAGG
CGGGTTTAAAAGCCACGCAG

Product: putative RNA 2'-O-ribose methyltransferase

Products: NA

Alternate protein names: 23S rRNA 2'-O-ribose methyltransferase rlmM

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MKNLFLFCRAGFEKECAAEIQQRAGELNVGGFVKANNNDAYVVYQCFEDDAADTLVKQLPLDSLIFARQMFAASDLLVDL
PENDRISPIVAALSDVSKAGEVRVETPDTNEAKELSAFCRKFTVPLRQHLKKSGSLLAQENPKRPIIHVCFIGPGRAYVG
YSYSNNSSPHFMGIPRLKMAADAPSRSSLKLDEAFGQFVPKEEQEERIRSGMNSVDLGACPGGWTYQLVRRGMFVSAVDN
GPMDEKLMETGQVKHYREDGFRFEPQRKNIYWLVCDMVEKPARVAELIEAWAINGWFKEAIFNLKLPMKSRYKEVTAILE
TMQTILKENGVTDFKVQCKHLYHDRDEVTVHLWLRPNTAWN

Sequences:

>Translated_361_residues
MKNLFLFCRAGFEKECAAEIQQRAGELNVGGFVKANNNDAYVVYQCFEDDAADTLVKQLPLDSLIFARQMFAASDLLVDL
PENDRISPIVAALSDVSKAGEVRVETPDTNEAKELSAFCRKFTVPLRQHLKKSGSLLAQENPKRPIIHVCFIGPGRAYVG
YSYSNNSSPHFMGIPRLKMAADAPSRSSLKLDEAFGQFVPKEEQEERIRSGMNSVDLGACPGGWTYQLVRRGMFVSAVDN
GPMDEKLMETGQVKHYREDGFRFEPQRKNIYWLVCDMVEKPARVAELIEAWAINGWFKEAIFNLKLPMKSRYKEVTAILE
TMQTILKENGVTDFKVQCKHLYHDRDEVTVHLWLRPNTAWN
>Mature_361_residues
MKNLFLFCRAGFEKECAAEIQQRAGELNVGGFVKANNNDAYVVYQCFEDDAADTLVKQLPLDSLIFARQMFAASDLLVDL
PENDRISPIVAALSDVSKAGEVRVETPDTNEAKELSAFCRKFTVPLRQHLKKSGSLLAQENPKRPIIHVCFIGPGRAYVG
YSYSNNSSPHFMGIPRLKMAADAPSRSSLKLDEAFGQFVPKEEQEERIRSGMNSVDLGACPGGWTYQLVRRGMFVSAVDN
GPMDEKLMETGQVKHYREDGFRFEPQRKNIYWLVCDMVEKPARVAELIEAWAINGWFKEAIFNLKLPMKSRYKEVTAILE
TMQTILKENGVTDFKVQCKHLYHDRDEVTVHLWLRPNTAWN

Specific function: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA

COG id: COG2933

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmE family. RlmM subfamily

Homologues:

Organism=Escherichia coli, GI1789171, Length=353, Percent_Identity=59.2067988668555, Blast_Score=446, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMM_SHEB2 (B8EAT7)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002358902.1
- ProteinModelPortal:   B8EAT7
- SMR:   B8EAT7
- GeneID:   7089061
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_2993
- HOGENOM:   HBG681972
- OMA:   LYCRPGF
- ProtClustDB:   PRK11760
- GO:   GO:0005737
- HAMAP:   MF_01551
- InterPro:   IPR011224
- InterPro:   IPR002877
- PIRSF:   PIRSF028774

Pfam domain/function: PF01728 FtsJ

EC number: NA

Molecular weight: Translated: 40968; Mature: 40968

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLFLFCRAGFEKECAAEIQQRAGELNVGGFVKANNNDAYVVYQCFEDDAADTLVKQLP
CCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEEECCCCHHHHHHHHCC
LDSLIFARQMFAASDLLVDLPENDRISPIVAALSDVSKAGEVRVETPDTNEAKELSAFCR
HHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHH
KFTVPLRQHLKKSGSLLAQENPKRPIIHVCFIGPGRAYVGYSYSNNSSPHFMGIPRLKMA
HHHHHHHHHHHHCCCEEECCCCCCCEEEEEEECCCCEEEEEEECCCCCCCEECCCCHHEC
ADAPSRSSLKLDEAFGQFVPKEEQEERIRSGMNSVDLGACPGGWTYQLVRRGMFVSAVDN
CCCCCCCCEEHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCEEEECCC
GPMDEKLMETGQVKHYREDGFRFEPQRKNIYWLVCDMVEKPARVAELIEAWAINGWFKEA
CCCHHHHHHHCCCHHHHCCCCEECCCCCCEEEEEECHHHCHHHHHHHHHHHHCCHHHHHH
IFNLKLPMKSRYKEVTAILETMQTILKENGVTDFKVQCKHLYHDRDEVTVHLWLRPNTAW
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCC
N
C
>Mature Secondary Structure
MKNLFLFCRAGFEKECAAEIQQRAGELNVGGFVKANNNDAYVVYQCFEDDAADTLVKQLP
CCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEEECCCCHHHHHHHHCC
LDSLIFARQMFAASDLLVDLPENDRISPIVAALSDVSKAGEVRVETPDTNEAKELSAFCR
HHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHH
KFTVPLRQHLKKSGSLLAQENPKRPIIHVCFIGPGRAYVGYSYSNNSSPHFMGIPRLKMA
HHHHHHHHHHHHCCCEEECCCCCCCEEEEEEECCCCEEEEEEECCCCCCCEECCCCHHEC
ADAPSRSSLKLDEAFGQFVPKEEQEERIRSGMNSVDLGACPGGWTYQLVRRGMFVSAVDN
CCCCCCCCEEHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCEEEECCC
GPMDEKLMETGQVKHYREDGFRFEPQRKNIYWLVCDMVEKPARVAELIEAWAINGWFKEA
CCCHHHHHHHCCCHHHHCCCCEECCCCCCEEEEEECHHHCHHHHHHHHHHHHCCHHHHHH
IFNLKLPMKSRYKEVTAILETMQTILKENGVTDFKVQCKHLYHDRDEVTVHLWLRPNTAW
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCC
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA