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The map label for this gene is tcpI [H]

Identifier: 126173484

GI number: 126173484

Start: 1432526

End: 1434094

Strand: Direct

Name: tcpI [H]

Synonym: Sbal_1246

Alternate gene names: 126173484

Gene position: 1432526-1434094 (Clockwise)

Preceding gene: 126173482

Following gene: 126173485

Centisome position: 27.94

GC content: 48.31

Gene sequence:

>1569_bases
ATGGAAATACAGCACAAAGTTTTAATTTTTATCAGTTTCACGCTGGTCACTCTGGGGAGTTTATTGCTTGCGGGGCTGCA
TCTTCCGAGCATTGTGCAGGCGTTGATCTTGGGCGCAATCACCTCTGGCTTAGTGGTGTGGGTGTGTTTGCGCGCAACGA
AGGCTAAGCTTGACACCGATGAGGCAAATACTAAGGCATTAAAAGATCAAAGCCTTCCAGCCCATGATATCAGTGTGCAA
ACCAGTAAAATTGCTATCGGTTCGGCTGAAGTGTCGCATTTTATTGATTTACTGAATAAATCAATTGAATCAAATGGCGA
GCATGCCAGTGCCATTGCGGTTGCCGCGGGGCAATTGAGTCACACTACGGCCCAACTTGGCGATAATGCCGCCGATATTT
TAGGTCAGGCACAAGAGGCCGAGCGCGTTAGCGTGCAGGGGCGTAGCCAAGCCCAAAAAGGTGTGGCGGCTATTCGCTCA
CTGAGTACGGATATTGATACCGCCGCCGAGCAAGTACAGGCGCTTAAGTCGCGAGCCGAAGAAATCCAAAAAATCACCGA
AGTGATTAACTCTGTTGCCGAGCAAACGAATTTGTTGGCGTTAAATGCGGCCATCGAAGCGGCTCGTGCGGGAGAGCAGG
GCCGAGGTTTTGCGGTTGTCGCAGACGAAGTTCGCAGCCTTGCGGGTAAAACCGCAGGTGCGACCCAAGATATCGGCAAG
ATGCTATTAGAAATCCGCAGCGAAACCGATAAAACCTCTGGGCTGATGGAAAGGGTCGTAACGCAAACCGCCGATGTGGT
CGCGGCTATGGGCGAGTTAGACGCGCATTTCACTGAGATTTCGGCCTCTGTGACTCAATCGGCCCATGCGTTAGGTGATA
TGGAAGATTCCCTCAAACAATATAACAACACCACTAATGACATTAGCCGCTCTGTGACTCAAATCCGTGATTCGTTAAAT
TCGACGGGTAAACAGAGTCATAGCGTATCAGAGCAGGCCTTTACTCTATCCTTGACCACCGAGGGTATTTTTAAAGCGCT
GTCTAAATGGGATACACAAACCTTCGATCAGCAGGTTTTGCAATTGGCCAATATGGCCGCTAAAGCGTGCGGTGACAAGT
TGGCACAAGGTTTAGCTAGCGGCAGTTTTAGCGAGACAGATTTGTTTAATCCTAAATATCAACCTATTGCTAATACTCAG
CCGCAGAAATACAGCACAGCTTTCGATCGTTATACCGATCAGCATTTTCCAACGATTCAAGAACCCATTCTGGCAAAACA
CAGCGAAATTATTTATGCGGGAGCCGTTGATAAAAAAGGTTATTTTCCGACCCATAATAAACGTTTCAGCCAAGCGCTGA
CGGGCAAGGTCGAAGTCGATATGGTGCATAATCGAACCAAACGCTTGTTTAATGATCCGACAGGGATCCGCTGCGGCGCT
CATACTGAGCCTGTATTACTGCAAACCTACAAACGGGATACGGGCGAAGTGATGCATGACTTGTCTGTGCCCATTTTTGT
GAATGGTAAACATTGGGGCGGATTTAGAGTGGGATTTAAGGCTAAGTAA

Upstream 100 bases:

>100_bases
AATCGATAGCAGCTGTAATTGATTGTAGCTGAACGAGGGCGAATGATTCGACTCTTAGCATTTCCCTTTCATTTTTACCT
TGCGCAGTTATGGGAAGTAT

Downstream 100 bases:

>100_bases
ATAATAGATAATCAAATTTAGGTTATTTACTCTAAAAAATGCATAAAAACGCACCTTGTCATGTGTTGTACTTGTGATCC
GTGGTGGGTAATTGGTTAAC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: TCP pilus biosynthesis protein tcpI [H]

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MEIQHKVLIFISFTLVTLGSLLLAGLHLPSIVQALILGAITSGLVVWVCLRATKAKLDTDEANTKALKDQSLPAHDISVQ
TSKIAIGSAEVSHFIDLLNKSIESNGEHASAIAVAAGQLSHTTAQLGDNAADILGQAQEAERVSVQGRSQAQKGVAAIRS
LSTDIDTAAEQVQALKSRAEEIQKITEVINSVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAGKTAGATQDIGK
MLLEIRSETDKTSGLMERVVTQTADVVAAMGELDAHFTEISASVTQSAHALGDMEDSLKQYNNTTNDISRSVTQIRDSLN
STGKQSHSVSEQAFTLSLTTEGIFKALSKWDTQTFDQQVLQLANMAAKACGDKLAQGLASGSFSETDLFNPKYQPIANTQ
PQKYSTAFDRYTDQHFPTIQEPILAKHSEIIYAGAVDKKGYFPTHNKRFSQALTGKVEVDMVHNRTKRLFNDPTGIRCGA
HTEPVLLQTYKRDTGEVMHDLSVPIFVNGKHWGGFRVGFKAK

Sequences:

>Translated_522_residues
MEIQHKVLIFISFTLVTLGSLLLAGLHLPSIVQALILGAITSGLVVWVCLRATKAKLDTDEANTKALKDQSLPAHDISVQ
TSKIAIGSAEVSHFIDLLNKSIESNGEHASAIAVAAGQLSHTTAQLGDNAADILGQAQEAERVSVQGRSQAQKGVAAIRS
LSTDIDTAAEQVQALKSRAEEIQKITEVINSVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAGKTAGATQDIGK
MLLEIRSETDKTSGLMERVVTQTADVVAAMGELDAHFTEISASVTQSAHALGDMEDSLKQYNNTTNDISRSVTQIRDSLN
STGKQSHSVSEQAFTLSLTTEGIFKALSKWDTQTFDQQVLQLANMAAKACGDKLAQGLASGSFSETDLFNPKYQPIANTQ
PQKYSTAFDRYTDQHFPTIQEPILAKHSEIIYAGAVDKKGYFPTHNKRFSQALTGKVEVDMVHNRTKRLFNDPTGIRCGA
HTEPVLLQTYKRDTGEVMHDLSVPIFVNGKHWGGFRVGFKAK
>Mature_522_residues
MEIQHKVLIFISFTLVTLGSLLLAGLHLPSIVQALILGAITSGLVVWVCLRATKAKLDTDEANTKALKDQSLPAHDISVQ
TSKIAIGSAEVSHFIDLLNKSIESNGEHASAIAVAAGQLSHTTAQLGDNAADILGQAQEAERVSVQGRSQAQKGVAAIRS
LSTDIDTAAEQVQALKSRAEEIQKITEVINSVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAGKTAGATQDIGK
MLLEIRSETDKTSGLMERVVTQTADVVAAMGELDAHFTEISASVTQSAHALGDMEDSLKQYNNTTNDISRSVTQIRDSLN
STGKQSHSVSEQAFTLSLTTEGIFKALSKWDTQTFDQQVLQLANMAAKACGDKLAQGLASGSFSETDLFNPKYQPIANTQ
PQKYSTAFDRYTDQHFPTIQEPILAKHSEIIYAGAVDKKGYFPTHNKRFSQALTGKVEVDMVHNRTKRLFNDPTGIRCGA
HTEPVLLQTYKRDTGEVMHDLSVPIFVNGKHWGGFRVGFKAK

Specific function: May function as an environmental regulator of TCP biogenesis. Negatively regulates the synthesis of the major pilin subunit of TCP (tcpA) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=239, Percent_Identity=36.8200836820084, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788194, Length=234, Percent_Identity=32.4786324786325, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1789453, Length=231, Percent_Identity=32.4675324675325, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI2367378, Length=203, Percent_Identity=33.4975369458128, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788195, Length=203, Percent_Identity=34.9753694581281, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 56268; Mature: 56268

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIQHKVLIFISFTLVTLGSLLLAGLHLPSIVQALILGAITSGLVVWVCLRATKAKLDTD
CCCCCEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EANTKALKDQSLPAHDISVQTSKIAIGSAEVSHFIDLLNKSIESNGEHASAIAVAAGQLS
CCHHHHHHHCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
HTTAQLGDNAADILGQAQEAERVSVQGRSQAQKGVAAIRSLSTDIDTAAEQVQALKSRAE
HHHHHHCCCHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIQKITEVINSVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAGKTAGATQDIGK
HHHHHHHHHHHHHHHHCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCCCHHHHHH
MLLEIRSETDKTSGLMERVVTQTADVVAAMGELDAHFTEISASVTQSAHALGDMEDSLKQ
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
YNNTTNDISRSVTQIRDSLNSTGKQSHSVSEQAFTLSLTTEGIFKALSKWDTQTFDQQVL
HCCCHHHHHHHHHHHHHHHHHCCCHHHCCCHHEEEEEECHHHHHHHHHHHCHHHHHHHHH
QLANMAAKACGDKLAQGLASGSFSETDLFNPKYQPIANTQPQKYSTAFDRYTDQHFPTIQ
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHH
EPILAKHSEIIYAGAVDKKGYFPTHNKRFSQALTGKVEVDMVHNRTKRLFNDPTGIRCGA
HHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCCCC
HTEPVLLQTYKRDTGEVMHDLSVPIFVNGKHWGGFRVGFKAK
CCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEECCCCCC
>Mature Secondary Structure
MEIQHKVLIFISFTLVTLGSLLLAGLHLPSIVQALILGAITSGLVVWVCLRATKAKLDTD
CCCCCEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EANTKALKDQSLPAHDISVQTSKIAIGSAEVSHFIDLLNKSIESNGEHASAIAVAAGQLS
CCHHHHHHHCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
HTTAQLGDNAADILGQAQEAERVSVQGRSQAQKGVAAIRSLSTDIDTAAEQVQALKSRAE
HHHHHHCCCHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIQKITEVINSVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAGKTAGATQDIGK
HHHHHHHHHHHHHHHHCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCCCHHHHHH
MLLEIRSETDKTSGLMERVVTQTADVVAAMGELDAHFTEISASVTQSAHALGDMEDSLKQ
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
YNNTTNDISRSVTQIRDSLNSTGKQSHSVSEQAFTLSLTTEGIFKALSKWDTQTFDQQVL
HCCCHHHHHHHHHHHHHHHHHCCCHHHCCCHHEEEEEECHHHHHHHHHHHCHHHHHHHHH
QLANMAAKACGDKLAQGLASGSFSETDLFNPKYQPIANTQPQKYSTAFDRYTDQHFPTIQ
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHH
EPILAKHSEIIYAGAVDKKGYFPTHNKRFSQALTGKVEVDMVHNRTKRLFNDPTGIRCGA
HHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCCCC
HTEPVLLQTYKRDTGEVMHDLSVPIFVNGKHWGGFRVGFKAK
CCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8005659 [H]