| Definition | Shewanella baltica OS155 chromosome, complete genome. |
|---|---|
| Accession | NC_009052 |
| Length | 5,127,376 |
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The map label for this gene is thrA [H]
Identifier: 126173465
GI number: 126173465
Start: 1409709
End: 1412177
Strand: Direct
Name: thrA [H]
Synonym: Sbal_1227
Alternate gene names: 126173465
Gene position: 1409709-1412177 (Clockwise)
Preceding gene: 126173462
Following gene: 126173466
Centisome position: 27.49
GC content: 49.37
Gene sequence:
>2469_bases ATGAAAGTAATGAAATTTGGTGGTACCTCGCTTGCAAATTGGCAGCGATTCTCGATGGCAGCGGATATCGTTGCTCAGTC ATCTAAGCTTGAACCCATAGCCACTGTGCTATCGGCCCCTGCAACTGTGACGAATGCTTTATTAGAAATGGTCGACGTAG CCGTTAAAGGTGAAGATTATTTACCTGTGCTGCAGCACGTTGAGTGGGTATTTACTTCGCTGTACCAAGACGCCGTTAAC TCAGTGTTGTCGAGTGAGCAAAGCGAACAGCTTTTTTCTGGACTCAATGCCCAGCTGGTGATCTGGCAGGATAGATTACG TGGTATCGGATTACTGCAAGAATGTCCCGATGGTATCCGCGCCGAAATCGTGGTTGCAGGTGAGCGTTTATCTGCAGCCT TGATGGAACAAGTGATGATTTCTAAGGGGATCACTTCGGCTCAGCTCGACCCACGCGCCTTATTTTTAGGTCGTGGTCGT CCGTTAGAATCTGTCGTTGATATAGCCGTGAGTAAGCCAAGGTTTCGCGCGTTGGCGCTAGGTGAAAAACGCGTATGGGT GATGCCGGGATTCACCGCCGCCGATGAACAGGGCAAAGTGGTGACGTTAGGCCGTAATGGTTCTGACTATTCTGCTGCCG TGCTCGCCGCCTGTTTGGATGCTTCGAGCTGCGAAATCTGGACCGATGTTGACGGTGTTTATAATACCGACCCACGGGTG GTTGCCGATGCTAAGTTGTTGTCACAACTGAGCTATCAAGAGGCAATGGAGCTTTCCTATTTTGGTGCTAAGGTGTTGCA TCCTAAGACTATTGCACCTATCGCCCAGTTCCATATTCCCTGTTATATCAAAAACAGTTTTAACCCTGATGCGCCCGGCA CTCTGGTATCAAACCAAGCTGATGAAACCGGCTTGCAGGTTAAAGCTATCTCTAATTTAGATAACCAGACCATGTTCGAT ATTTCAGGCCCAGGTATGAAAGGCATGGTTGGCATGGCGAGCCGCACTTTAGCGGCGATTTCCCGCAGCGGCGTATCTGT GTCTTTAATCACCCAAAGTTCTTCTGAATACAGCATTAGCTTCTGTGTGGCTACATCTGATTCGGCCAAAGTGAAGTGGG CATTAGAGCAAGAATTTGAATTAGAAATAAAAAGTGATTTACTTGAGCCTATCGCTATGCGCCATGAGCTGGCAATTGTG TCCTTGATTGGTGATGGCATGCGCACCCATAAAGGGGTGGCGGCGCGTTTCTTCCAAGCGTTAGCGCAGGCGAGTGTGAA CATTATCGCCATCGCCCAAGGTTCGTCCGAGCGCTCGATTTCGACTGTGATCGAGCAGCGTAAGACTAAGCATGCGGTGG CGGCGTGTCATCAAGGCTTTTTCGATGTGCAGCAATATTTAGATGTGTTTTTAGTGGGATGCGGCAACGTGGGTGCTGGT CTGCTCGAGCAGATAAAACAACAGTCCGCCATGCTCAAAGAGCAGCACATCAGTATCCGTGTTTGCGGCATAGTGAATTC GAACAAGATGTTACTCGACAGTGCAGGCATTGATTTAAGCAACTGGTCTAGCTTGCTTGCCGATAGTCAGCAAGCCTGTG ATATCCCAGCGTTACTGGCATGGGCGAAAGAGCAACAATTACTAAACCCTGTGCTGGTGGATTGTACTTCGAGCGAGCAA GTGTCGGATCTGTATTTGGATGTGATGAACTCAGGTTTGCATGTGGTCACGCCGAACAAAAAGTCGAACACTCGCGATTA TGCTTATTACCAAGCGCTTCGCCAAACAGCCTTAAAACAGCGCCGCCAATTTTTATACGAAACCACAGTCGGCGCGGGTT TACCTGTTATCGATAACCTGAAAAAACTGTTATTTGCGGGCGATAAGCTGCATAAGTTCAACGGTATTTTATCGGGCTCT TTATCCTTTATCTTCGGCATGCTCGATGAAGGCATGACACTCTCTGAAGCGACAGGTCTTGCGCGGGAAAAATGCTTTAC TGAGCCAGATCCCCGTGATGATTTGAGCGGTATGGATGTGGCGCGTAAGGTGCTCATACTTGCCCGTGAAGTGGGACTAA AGCTAGAACTCAGTGACGTGCAGGTTGAATCTGTATTGCCAGCCGAGTTTGATGATTCAGGTGATGTTGAGAGCTTTATG GCGCGTTTGCCGCAGGTTGATGCGGCGATTGCCGCTAAAGTGGCGCAGGCCAAAGCCCAAGGTAAAGTGCTGCGTTATGT GGGGCAAATTGAAGATGGCGTCTGCCGAGTGCGTATCGCCGAAGTCGATGCACAGGATCCCCTTTATAGTGTTAAAGGCG GCGAAAATGCCTTGGCATTCTACAGCCGTTATTATCAGCCCATTCCGTTTGTGCTGCGCGGTTATGGCGCGGGAACGGAA GTGACTGCCGCTGGCGCTTTTGCCGATGTATTAAGAACCTTGAATTGGACTCGTGAGGTGAGTGTATGA
Upstream 100 bases:
>100_bases ACCCTAAAGAATTTTAACAATGAGCCCGCTTCCCACAAAGAAACGGGCTTTTTTGTTTCTAGCTCTTATTTCTAAGTCGG GCGCGGTACAGGAGAACAAG
Downstream 100 bases:
>100_bases GTTTGACCGTTTACGCTCCAGCCTCTATGGGTAACGTGGGAGTCGGATTTGATTTACTGGGCGCCGCTTTGGCGCCTATC GATGGCAGTTTACTGGGCGA
Product: bifunctional aspartokinase I/homoserine dehydrogenase I
Products: NA
Alternate protein names: Aspartokinase I/homoserine dehydrogenase I; AKI-HDI; Aspartokinase; Homoserine dehydrogenase [H]
Number of amino acids: Translated: 822; Mature: 822
Protein sequence:
>822_residues MKVMKFGGTSLANWQRFSMAADIVAQSSKLEPIATVLSAPATVTNALLEMVDVAVKGEDYLPVLQHVEWVFTSLYQDAVN SVLSSEQSEQLFSGLNAQLVIWQDRLRGIGLLQECPDGIRAEIVVAGERLSAALMEQVMISKGITSAQLDPRALFLGRGR PLESVVDIAVSKPRFRALALGEKRVWVMPGFTAADEQGKVVTLGRNGSDYSAAVLAACLDASSCEIWTDVDGVYNTDPRV VADAKLLSQLSYQEAMELSYFGAKVLHPKTIAPIAQFHIPCYIKNSFNPDAPGTLVSNQADETGLQVKAISNLDNQTMFD ISGPGMKGMVGMASRTLAAISRSGVSVSLITQSSSEYSISFCVATSDSAKVKWALEQEFELEIKSDLLEPIAMRHELAIV SLIGDGMRTHKGVAARFFQALAQASVNIIAIAQGSSERSISTVIEQRKTKHAVAACHQGFFDVQQYLDVFLVGCGNVGAG LLEQIKQQSAMLKEQHISIRVCGIVNSNKMLLDSAGIDLSNWSSLLADSQQACDIPALLAWAKEQQLLNPVLVDCTSSEQ VSDLYLDVMNSGLHVVTPNKKSNTRDYAYYQALRQTALKQRRQFLYETTVGAGLPVIDNLKKLLFAGDKLHKFNGILSGS LSFIFGMLDEGMTLSEATGLAREKCFTEPDPRDDLSGMDVARKVLILAREVGLKLELSDVQVESVLPAEFDDSGDVESFM ARLPQVDAAIAAKVAQAKAQGKVLRYVGQIEDGVCRVRIAEVDAQDPLYSVKGGENALAFYSRYYQPIPFVLRGYGAGTE VTAAGAFADVLRTLNWTREVSV
Sequences:
>Translated_822_residues MKVMKFGGTSLANWQRFSMAADIVAQSSKLEPIATVLSAPATVTNALLEMVDVAVKGEDYLPVLQHVEWVFTSLYQDAVN SVLSSEQSEQLFSGLNAQLVIWQDRLRGIGLLQECPDGIRAEIVVAGERLSAALMEQVMISKGITSAQLDPRALFLGRGR PLESVVDIAVSKPRFRALALGEKRVWVMPGFTAADEQGKVVTLGRNGSDYSAAVLAACLDASSCEIWTDVDGVYNTDPRV VADAKLLSQLSYQEAMELSYFGAKVLHPKTIAPIAQFHIPCYIKNSFNPDAPGTLVSNQADETGLQVKAISNLDNQTMFD ISGPGMKGMVGMASRTLAAISRSGVSVSLITQSSSEYSISFCVATSDSAKVKWALEQEFELEIKSDLLEPIAMRHELAIV SLIGDGMRTHKGVAARFFQALAQASVNIIAIAQGSSERSISTVIEQRKTKHAVAACHQGFFDVQQYLDVFLVGCGNVGAG LLEQIKQQSAMLKEQHISIRVCGIVNSNKMLLDSAGIDLSNWSSLLADSQQACDIPALLAWAKEQQLLNPVLVDCTSSEQ VSDLYLDVMNSGLHVVTPNKKSNTRDYAYYQALRQTALKQRRQFLYETTVGAGLPVIDNLKKLLFAGDKLHKFNGILSGS LSFIFGMLDEGMTLSEATGLAREKCFTEPDPRDDLSGMDVARKVLILAREVGLKLELSDVQVESVLPAEFDDSGDVESFM ARLPQVDAAIAAKVAQAKAQGKVLRYVGQIEDGVCRVRIAEVDAQDPLYSVKGGENALAFYSRYYQPIPFVLRGYGAGTE VTAAGAFADVLRTLNWTREVSV >Mature_822_residues MKVMKFGGTSLANWQRFSMAADIVAQSSKLEPIATVLSAPATVTNALLEMVDVAVKGEDYLPVLQHVEWVFTSLYQDAVN SVLSSEQSEQLFSGLNAQLVIWQDRLRGIGLLQECPDGIRAEIVVAGERLSAALMEQVMISKGITSAQLDPRALFLGRGR PLESVVDIAVSKPRFRALALGEKRVWVMPGFTAADEQGKVVTLGRNGSDYSAAVLAACLDASSCEIWTDVDGVYNTDPRV VADAKLLSQLSYQEAMELSYFGAKVLHPKTIAPIAQFHIPCYIKNSFNPDAPGTLVSNQADETGLQVKAISNLDNQTMFD ISGPGMKGMVGMASRTLAAISRSGVSVSLITQSSSEYSISFCVATSDSAKVKWALEQEFELEIKSDLLEPIAMRHELAIV SLIGDGMRTHKGVAARFFQALAQASVNIIAIAQGSSERSISTVIEQRKTKHAVAACHQGFFDVQQYLDVFLVGCGNVGAG LLEQIKQQSAMLKEQHISIRVCGIVNSNKMLLDSAGIDLSNWSSLLADSQQACDIPALLAWAKEQQLLNPVLVDCTSSEQ VSDLYLDVMNSGLHVVTPNKKSNTRDYAYYQALRQTALKQRRQFLYETTVGAGLPVIDNLKKLLFAGDKLHKFNGILSGS LSFIFGMLDEGMTLSEATGLAREKCFTEPDPRDDLSGMDVARKVLILAREVGLKLELSDVQVESVLPAEFDDSGDVESFM ARLPQVDAAIAAKVAQAKAQGKVLRYVGQIEDGVCRVRIAEVDAQDPLYSVKGGENALAFYSRYYQPIPFVLRGYGAGTE VTAAGAFADVLRTLNWTREVSV
Specific function: Catalyzes 2 nonconsecutive reactions in the common biosynthetic pathway leading from Asp to diaminopimelate and Lys, to Met, and to Thr and Ile. [C]
COG id: COG0527
COG function: function code E; Aspartokinases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ACT domains [H]
Homologues:
Organism=Escherichia coli, GI1786183, Length=821, Percent_Identity=57.3690621193666, Blast_Score=940, Evalue=0.0, Organism=Escherichia coli, GI1790376, Length=817, Percent_Identity=31.2117503059976, Blast_Score=362, Evalue=1e-101, Organism=Escherichia coli, GI1790455, Length=473, Percent_Identity=30.0211416490486, Blast_Score=170, Evalue=4e-43, Organism=Saccharomyces cerevisiae, GI6322599, Length=338, Percent_Identity=31.0650887573964, Blast_Score=161, Evalue=3e-40, Organism=Saccharomyces cerevisiae, GI6320893, Length=497, Percent_Identity=26.1569416498994, Blast_Score=142, Evalue=3e-34,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002912 - InterPro: IPR001048 - InterPro: IPR005106 - InterPro: IPR001341 - InterPro: IPR018042 - InterPro: IPR011147 - InterPro: IPR001342 - InterPro: IPR019811 - InterPro: IPR016040 [H]
Pfam domain/function: PF00696 AA_kinase; PF01842 ACT; PF00742 Homoserine_dh; PF03447 NAD_binding_3 [H]
EC number: =2.7.2.4; =1.1.1.3 [H]
Molecular weight: Translated: 89200; Mature: 89200
Theoretical pI: Translated: 5.02; Mature: 5.02
Prosite motif: PS00324 ASPARTOKINASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 4.0 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 4.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKVMKFGGTSLANWQRFSMAADIVAQSSKLEPIATVLSAPATVTNALLEMVDVAVKGEDY CCEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCC LPVLQHVEWVFTSLYQDAVNSVLSSEQSEQLFSGLNAQLVIWQDRLRGIGLLQECPDGIR HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEEEHHHCCCCHHHHCCCCCE AEIVVAGERLSAALMEQVMISKGITSAQLDPRALFLGRGRPLESVVDIAVSKPRFRALAL EEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCEEEEEE GEKRVWVMPGFTAADEQGKVVTLGRNGSDYSAAVLAACLDASSCEIWTDVDGVYNTDPRV CCCEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCE VADAKLLSQLSYQEAMELSYFGAKVLHPKTIAPIAQFHIPCYIKNSFNPDAPGTLVSNQA EHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHCCCEEEECCCCCCCCCCEECCCC DETGLQVKAISNLDNQTMFDISGPGMKGMVGMASRTLAAISRSGVSVSLITQSSSEYSIS CCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEE FCVATSDSAKVKWALEQEFELEIKSDLLEPIAMRHELAIVSLIGDGMRTHKGVAARFFQA EEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH LAQASVNIIAIAQGSSERSISTVIEQRKTKHAVAACHQGFFDVQQYLDVFLVGCGNVGAG HHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHH LLEQIKQQSAMLKEQHISIRVCGIVNSNKMLLDSAGIDLSNWSSLLADSQQACDIPALLA HHHHHHHHHHHHHHHCCEEEEEEEECCCEEEEEECCCCHHHHHHHHHCCHHHCCCHHHHH WAKEQQLLNPVLVDCTSSEQVSDLYLDVMNSGLHVVTPNKKSNTRDYAYYQALRQTALKQ HHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHH RRQFLYETTVGAGLPVIDNLKKLLFAGDKLHKFNGILSGSLSFIFGMLDEGMTLSEATGL HHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH AREKCFTEPDPRDDLSGMDVARKVLILAREVGLKLELSDVQVESVLPAEFDDSGDVESFM HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCEEEECCCCCCCCCCCCHHHHH ARLPQVDAAIAAKVAQAKAQGKVLRYVGQIEDGVCRVRIAEVDAQDPLYSVKGGENALAF HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEECCCCHHHHH YSRYYQPIPFVLRGYGAGTEVTAAGAFADVLRTLNWTREVSV HHHHCCCCCHHHCCCCCCCCEEHHHHHHHHHHHHCCHHCCCC >Mature Secondary Structure MKVMKFGGTSLANWQRFSMAADIVAQSSKLEPIATVLSAPATVTNALLEMVDVAVKGEDY CCEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCC LPVLQHVEWVFTSLYQDAVNSVLSSEQSEQLFSGLNAQLVIWQDRLRGIGLLQECPDGIR HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEEEHHHCCCCHHHHCCCCCE AEIVVAGERLSAALMEQVMISKGITSAQLDPRALFLGRGRPLESVVDIAVSKPRFRALAL EEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCEEEEEE GEKRVWVMPGFTAADEQGKVVTLGRNGSDYSAAVLAACLDASSCEIWTDVDGVYNTDPRV CCCEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCE VADAKLLSQLSYQEAMELSYFGAKVLHPKTIAPIAQFHIPCYIKNSFNPDAPGTLVSNQA EHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHCCCEEEECCCCCCCCCCEECCCC DETGLQVKAISNLDNQTMFDISGPGMKGMVGMASRTLAAISRSGVSVSLITQSSSEYSIS CCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEE FCVATSDSAKVKWALEQEFELEIKSDLLEPIAMRHELAIVSLIGDGMRTHKGVAARFFQA EEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH LAQASVNIIAIAQGSSERSISTVIEQRKTKHAVAACHQGFFDVQQYLDVFLVGCGNVGAG HHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHH LLEQIKQQSAMLKEQHISIRVCGIVNSNKMLLDSAGIDLSNWSSLLADSQQACDIPALLA HHHHHHHHHHHHHHHCCEEEEEEEECCCEEEEEECCCCHHHHHHHHHCCHHHCCCHHHHH WAKEQQLLNPVLVDCTSSEQVSDLYLDVMNSGLHVVTPNKKSNTRDYAYYQALRQTALKQ HHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHH RRQFLYETTVGAGLPVIDNLKKLLFAGDKLHKFNGILSGSLSFIFGMLDEGMTLSEATGL HHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH AREKCFTEPDPRDDLSGMDVARKVLILAREVGLKLELSDVQVESVLPAEFDDSGDVESFM HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCEEEECCCCCCCCCCCCHHHHH ARLPQVDAAIAAKVAQAKAQGKVLRYVGQIEDGVCRVRIAEVDAQDPLYSVKGGENALAF HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEECCCCHHHHH YSRYYQPIPFVLRGYGAGTEVTAAGAFADVLRTLNWTREVSV HHHHCCCCCHHHCCCCCCCCEEHHHHHHHHHHHHCCHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7003595; 1630901; 7610040; 9278503; 6277952; 2410621; 387092; 6298218; 390305 [H]