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The map label for this gene is pheA [H]

Identifier: 126173458

GI number: 126173458

Start: 1401615

End: 1403609

Strand: Reverse

Name: pheA [H]

Synonym: Sbal_1220

Alternate gene names: 126173458

Gene position: 1403609-1401615 (Counterclockwise)

Preceding gene: 126173459

Following gene: 126173446

Centisome position: 27.37

GC content: 46.67

Gene sequence:

>1995_bases
ATGCATACACCACAGCCTTTAAATCAAACCCGAGAGCAGATCACCAATCTGGATAATGAACTGCTGGCATTACTCGCAGA
GCGCCGTCGCTTAAGTCTAGAAGTGGCCCGTAGTAAAGAAGTGGATGTCAGACCCATCAGAGATACTCAAAGGGAGAAAG
AACTGCTCGCTAGACTGGTGAAAGAAGGCAGAGAAAAGGGATTAGATGCCCACTATGTTATCTCCCTTTATCAAAGCATC
ATTGAAGATTCAGTATTGAATCAACAAGCTTACCTTCACGGCCGTGCCAACCCAGAAACACAAAAACAGCAGTATTGTAT
CGCCTACCTCGGTGCACGAGGCTCTTACTCTTATCTCGCAGCAACCCGCTATTGCCAACGCCGCCAAGTTGAAATGCTGG
ACTTAGGTTGCCAAAGTTTCGATGAAATAGTGCAAGCCGTTGAGTCTGGGCATGCTGATTATGGTTTCCTGCCGATTGAG
AACACTTCCTCGGGTTCAATCAACGAAGTCTACGATGTACTGCAGCACACCAGTCTATCGATCGTGGGTGAAACGACGAT
TGAAGTCAGCCATTGCCTACTAGGAAAAGCTGGCAGTAAATTAGCTGACATCAAAACTGTCTATGCCCACCCTCAGCCTA
TTAGCCAATGCAGCAGATATTTAAGTCAGCACAAAGACTTGAGACTGGAGTACTGCTCAAGCAGCGCAGAAGCAATGGAC
AAGGTAAACCAAAGTCCAGATAACAGTGCAGCAGCCATTGGTAGCGCCGAAGGTGGTGCACTCTATCAACTAGAGTCGAT
AGAAGCGGGCTTAGCGAATCAGAAGATCAATCAAAGCCGCTTTATCGTTGTTGCCCGCAAAGCGGTTGCCGTGCCAGAGC
AGTTACCCGCTAAGACCACGTTGATCATGGCGACGGGCCAAAAAGCTGGGGCTTTAGTGGAAGCTCTGCTGGTTCTGAAG
GCGCATCAGTTAAACATGAGCAAATTAGAGTCACGCCCGATCCCAGGAACACCTTGGGAAGAGATGTTCTATTTAGATAT
CGACGCGAATATCTCCAGTGAATCTATGCAGGCGGGTTTAAAGCAACTCGAGCGGCTCACCCGTTTCATCAAAGTATTAG
GCTGTTATCCTTGTGAAACAGTCAAGCCCACGCAGCTAAGCAACAGCCAGTTACTGATTGAACCTAGCACCTCTAAGGAC
CAAGTCATCAGCGAGAATGGAGTAAATACCAGCCCTGTTCGATATAGCAAAGCCTATAAAGAGCAAGCTAGTGAGATCAA
CTGCGGTGCAATGACAATCGGTGCAGGGCATGTCGGTGCCATAGCGCAAATCACGCTGAATAATGACATTTCACACTTAG
CGTTATCGGCTTTCGAGCAGCAAGTGAAACAGCTTAAAGAAGCGGGATTCCAAGCGGTTCTACTTAATGCTGTTAATCAA
ATGGCTATGGCGGAATTGACCCTCGCTAAACTGCGCCAAATCCTGCATCAATATGGTCTAGTGTGCATTATTGCCATAGA
GCAAGAAGCCGATATGCCATTAGCCGTTCAGCACGCCGATATGCTGTTTCTAGCGGGTAAGCAGATGTTTAATCAAACCT
TACTCACTCAAGCGGGTACGTTGCCAACACCTTTGATACTTGAACGTAACGATATGGCAAGTTTTGAAGAATTACTCACG
GCAACAGAAGTGATCTTAAGCCAAGGTAATCAGCAACTGATCCTGTGTGACTCTGGCATTAGAACCTTAAATAACGCCAA
TCTACCTTCACTCGATTTAACGAGCCTGATCCAGATTAAAGCCACGAGTCATTTGCCCATTTTGATCAACCCTAGCTATG
CCGTATCAGATGATGCCCTACTGGTTCAAACCCAAGGTATTAAGCAGCTTAAAGTGGATGGATTGATACTCAATTGTCCA
CTCGATAGCCATGATGACCATGAGTCGCTTAACTTAATTAGCGCTGTAGTGCGGGAATTATATCGGGCTAACTAA

Upstream 100 bases:

>100_bases
TTACTGTGTAAAAACGAAAGTAAAAATCCAAAGCCTCCCAACTGGGAGGCTTTTTTGTCTTAAACGATTGATAAAATACA
TGGCGGCAATTGAGGTCAGA

Downstream 100 bases:

>100_bases
CGCTTTGATCTTGATTGATTTAATCTTAACTGAAATGTGGTTAGTTCGAAGTGTATTCAGGGATAAATGAGACTTCTTTT
ATCCCTGATTGACTGAAATA

Product: chorismate mutase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 664; Mature: 664

Protein sequence:

>664_residues
MHTPQPLNQTREQITNLDNELLALLAERRRLSLEVARSKEVDVRPIRDTQREKELLARLVKEGREKGLDAHYVISLYQSI
IEDSVLNQQAYLHGRANPETQKQQYCIAYLGARGSYSYLAATRYCQRRQVEMLDLGCQSFDEIVQAVESGHADYGFLPIE
NTSSGSINEVYDVLQHTSLSIVGETTIEVSHCLLGKAGSKLADIKTVYAHPQPISQCSRYLSQHKDLRLEYCSSSAEAMD
KVNQSPDNSAAAIGSAEGGALYQLESIEAGLANQKINQSRFIVVARKAVAVPEQLPAKTTLIMATGQKAGALVEALLVLK
AHQLNMSKLESRPIPGTPWEEMFYLDIDANISSESMQAGLKQLERLTRFIKVLGCYPCETVKPTQLSNSQLLIEPSTSKD
QVISENGVNTSPVRYSKAYKEQASEINCGAMTIGAGHVGAIAQITLNNDISHLALSAFEQQVKQLKEAGFQAVLLNAVNQ
MAMAELTLAKLRQILHQYGLVCIIAIEQEADMPLAVQHADMLFLAGKQMFNQTLLTQAGTLPTPLILERNDMASFEELLT
ATEVILSQGNQQLILCDSGIRTLNNANLPSLDLTSLIQIKATSHLPILINPSYAVSDDALLVQTQGIKQLKVDGLILNCP
LDSHDDHESLNLISAVVRELYRAN

Sequences:

>Translated_664_residues
MHTPQPLNQTREQITNLDNELLALLAERRRLSLEVARSKEVDVRPIRDTQREKELLARLVKEGREKGLDAHYVISLYQSI
IEDSVLNQQAYLHGRANPETQKQQYCIAYLGARGSYSYLAATRYCQRRQVEMLDLGCQSFDEIVQAVESGHADYGFLPIE
NTSSGSINEVYDVLQHTSLSIVGETTIEVSHCLLGKAGSKLADIKTVYAHPQPISQCSRYLSQHKDLRLEYCSSSAEAMD
KVNQSPDNSAAAIGSAEGGALYQLESIEAGLANQKINQSRFIVVARKAVAVPEQLPAKTTLIMATGQKAGALVEALLVLK
AHQLNMSKLESRPIPGTPWEEMFYLDIDANISSESMQAGLKQLERLTRFIKVLGCYPCETVKPTQLSNSQLLIEPSTSKD
QVISENGVNTSPVRYSKAYKEQASEINCGAMTIGAGHVGAIAQITLNNDISHLALSAFEQQVKQLKEAGFQAVLLNAVNQ
MAMAELTLAKLRQILHQYGLVCIIAIEQEADMPLAVQHADMLFLAGKQMFNQTLLTQAGTLPTPLILERNDMASFEELLT
ATEVILSQGNQQLILCDSGIRTLNNANLPSLDLTSLIQIKATSHLPILINPSYAVSDDALLVQTQGIKQLKVDGLILNCP
LDSHDDHESLNLISAVVRELYRAN
>Mature_664_residues
MHTPQPLNQTREQITNLDNELLALLAERRRLSLEVARSKEVDVRPIRDTQREKELLARLVKEGREKGLDAHYVISLYQSI
IEDSVLNQQAYLHGRANPETQKQQYCIAYLGARGSYSYLAATRYCQRRQVEMLDLGCQSFDEIVQAVESGHADYGFLPIE
NTSSGSINEVYDVLQHTSLSIVGETTIEVSHCLLGKAGSKLADIKTVYAHPQPISQCSRYLSQHKDLRLEYCSSSAEAMD
KVNQSPDNSAAAIGSAEGGALYQLESIEAGLANQKINQSRFIVVARKAVAVPEQLPAKTTLIMATGQKAGALVEALLVLK
AHQLNMSKLESRPIPGTPWEEMFYLDIDANISSESMQAGLKQLERLTRFIKVLGCYPCETVKPTQLSNSQLLIEPSTSKD
QVISENGVNTSPVRYSKAYKEQASEINCGAMTIGAGHVGAIAQITLNNDISHLALSAFEQQVKQLKEAGFQAVLLNAVNQ
MAMAELTLAKLRQILHQYGLVCIIAIEQEADMPLAVQHADMLFLAGKQMFNQTLLTQAGTLPTPLILERNDMASFEELLT
ATEVILSQGNQQLILCDSGIRTLNNANLPSLDLTSLIQIKATSHLPILINPSYAVSDDALLVQTQGIKQLKVDGLILNCP
LDSHDDHESLNLISAVVRELYRAN

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=386, Percent_Identity=54.4041450777202, Blast_Score=428, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6324013, Length=294, Percent_Identity=25.8503401360544, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 73058; Mature: 73058

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTPQPLNQTREQITNLDNELLALLAERRRLSLEVARSKEVDVRPIRDTQREKELLARLV
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
KEGREKGLDAHYVISLYQSIIEDSVLNQQAYLHGRANPETQKQQYCIAYLGARGSYSYLA
HHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHEECCCCCCHHHHHEEEEEECCCCCHHHHH
ATRYCQRRQVEMLDLGCQSFDEIVQAVESGHADYGFLPIENTSSGSINEVYDVLQHTSLS
HHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHCCEE
IVGETTIEVSHCLLGKAGSKLADIKTVYAHPQPISQCSRYLSQHKDLRLEYCSSSAEAMD
EEECCHHHHHHHHHCCCCCCHHHHHHEECCCCCHHHHHHHHHHCCCCCHHHHCCHHHHHH
KVNQSPDNSAAAIGSAEGGALYQLESIEAGLANQKINQSRFIVVARKAVAVPEQLPAKTT
HHCCCCCCCCEECCCCCCCCEEEEHHHHHCHHCCCCCCCEEEEEEHHHHCCCCCCCCCEE
LIMATGQKAGALVEALLVLKAHQLNMSKLESRPIPGTPWEEMFYLDIDANISSESMQAGL
EEEECCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHEEEEEECCCCCHHHHHHHH
KQLERLTRFIKVLGCYPCETVKPTQLSNSQLLIEPSTSKDQVISENGVNTSPVRYSKAYK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHCCCCCCCCCHHHHHHH
EQASEINCGAMTIGAGHVGAIAQITLNNDISHLALSAFEQQVKQLKEAGFQAVLLNAVNQ
HHHCCCCCCEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
MAMAELTLAKLRQILHQYGLVCIIAIEQEADMPLAVQHADMLFLAGKQMFNQTLLTQAGT
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCC
LPTPLILERNDMASFEELLTATEVILSQGNQQLILCDSGIRTLNNANLPSLDLTSLIQIK
CCCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHCCCCCCCCCCHHHEEEEE
ATSHLPILINPSYAVSDDALLVQTQGIKQLKVDGLILNCPLDSHDDHESLNLISAVVREL
ECCCCEEEECCCCEECCCEEEEEECCCCEEEECCEEEECCCCCCCCHHHHHHHHHHHHHH
YRAN
HHCC
>Mature Secondary Structure
MHTPQPLNQTREQITNLDNELLALLAERRRLSLEVARSKEVDVRPIRDTQREKELLARLV
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
KEGREKGLDAHYVISLYQSIIEDSVLNQQAYLHGRANPETQKQQYCIAYLGARGSYSYLA
HHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHEECCCCCCHHHHHEEEEEECCCCCHHHHH
ATRYCQRRQVEMLDLGCQSFDEIVQAVESGHADYGFLPIENTSSGSINEVYDVLQHTSLS
HHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHCCEE
IVGETTIEVSHCLLGKAGSKLADIKTVYAHPQPISQCSRYLSQHKDLRLEYCSSSAEAMD
EEECCHHHHHHHHHCCCCCCHHHHHHEECCCCCHHHHHHHHHHCCCCCHHHHCCHHHHHH
KVNQSPDNSAAAIGSAEGGALYQLESIEAGLANQKINQSRFIVVARKAVAVPEQLPAKTT
HHCCCCCCCCEECCCCCCCCEEEEHHHHHCHHCCCCCCCEEEEEEHHHHCCCCCCCCCEE
LIMATGQKAGALVEALLVLKAHQLNMSKLESRPIPGTPWEEMFYLDIDANISSESMQAGL
EEEECCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHEEEEEECCCCCHHHHHHHH
KQLERLTRFIKVLGCYPCETVKPTQLSNSQLLIEPSTSKDQVISENGVNTSPVRYSKAYK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHCCCCCCCCCHHHHHHH
EQASEINCGAMTIGAGHVGAIAQITLNNDISHLALSAFEQQVKQLKEAGFQAVLLNAVNQ
HHHCCCCCCEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
MAMAELTLAKLRQILHQYGLVCIIAIEQEADMPLAVQHADMLFLAGKQMFNQTLLTQAGT
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCC
LPTPLILERNDMASFEELLTATEVILSQGNQQLILCDSGIRTLNNANLPSLDLTSLIQIK
CCCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHCCCCCCCCCCHHHEEEEE
ATSHLPILINPSYAVSDDALLVQTQGIKQLKVDGLILNCPLDSHDDHESLNLISAVVREL
ECCCCEEEECCCCEECCCEEEEEECCCCEEEECCEEEECCCCCCCCHHHHHHHHHHHHHH
YRAN
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]