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The map label for this gene is bglB [H]

Identifier: 126173371

GI number: 126173371

Start: 1302598

End: 1303953

Strand: Reverse

Name: bglB [H]

Synonym: Sbal_1131

Alternate gene names: 126173371

Gene position: 1303953-1302598 (Counterclockwise)

Preceding gene: 126173377

Following gene: 126173370

Centisome position: 25.43

GC content: 45.06

Gene sequence:

>1356_bases
ATGAAAATATCTTTACCAAAGAACTCGAGACTCCAAAGCGAAGCGTTTACTTTTGGTGTTGCGACCGCTTCCTTTCAAAT
CGAAGGTGGCGTGGACTCTCGCCAAACCTGTATTTGGGATACCTTCTGTGCAACACCAGATAAAATCCGTGATGCCTCCA
ATGGCGATATCGCCTGCAACCACCTGAATCTATGGCAAGAAGATATCGCCTTAATCACGTCACTCGGGGTTGATGCCTAT
CGTTTTTCCATCGCATGGGGACGGGTCTTAAATCAAGATGGCAGCATTAATCAGCAGGGAGTTGATTTCTACATTGGCAT
TCTAGACGAACTAAAACGTAGAAATATCAAAGCATTTGTCACGCTTTACCATTGGGATCTTCCTCAACATATTGAGGATC
AAGGCGGCTGGTTAAACCGAGATACCGCTTACCTTTTCAAAGACTATGCTGACAAAATAAGCCAAGCCTTCGGCGACCGA
GTGTATTCCTACGCCACTTTAAACGAACCCTTTTGCAGCTCATATTTAGGCTATGAGGCAGGCATTCACGCCCCAGGTTT
AATGAAAAAAGCCTATGGTCGTCAATCGGCTCACCACCTATTGCTCGCCCACGGCTTAGCGATGCAAGTGCTGCAAAAGA
ACAGCCCTAACAGCATGAATGGCATAGTTCTTAACTTCACGCCTTGCTACGCATTAACCCAAAGTGCTGCCGATATTCAA
GCCGCAAAACAAGCCGATGATTACTTTAACCAGTGGTATATCAAGCCCATTTTCGATGCGGCATACCCAGACCTTCTCGC
AGCATTAGCGCCAGAAGACAGACCGGAAATTCACGACGGCGACCTTGAGCTTATCAGTCAACCAATTGATTTTTTAGGGG
TTAACTTTTATACCCGCGCCGTATATCAGGCCGATGCAGAACAAGGATTTGTGCAAGTTGATTTACCTGGGGTACCTAAA
ACTGACATAGGCTGGGAGATCCATCCACAGGCCTTTACCGATTTACTGGTTTCTTTAAATCAAACCTATGATTTACCGCC
TATTTTCATCACAGAAAATGGTGCCGCTATGGACGATAAATGCATTGATGGGCGTGTCGATGACTTCGATAGGCTCAGCT
ATTACCAGCACCATTTAACCGCAGTAGACAATGCCATAGTACAAGGTGTTAACATTCAGGGTTACTTTGCCTGGAGCTTG
ATGGATAATTTTGAGTGGGCCGAAGGCTACTTAAAACGTTTTGGCATTGTCTATGTGGATTATGCAAGCCAAACCAGAAC
GATAAAGGCCAGTGGTCAAGCCTACAGCGACTTAATTCGCTCAAGGGCTCACTTTACTAATAACAATAATAAATAA

Upstream 100 bases:

>100_bases
TTTTAGTGACAGTCGGCAAGCATCTTTACTCTCTTTATCTTGAACTCTGTGTTTTAAATCGCAGGCATGAATTCAAAAAT
ATAATTAAGTGACTGAATAT

Downstream 100 bases:

>100_bases
GGCTAAAGCCATGATTAGCATAAAAGAAAAAATAGCCTATGGGCTTGGCGACACTGCCAGCAACATCGTTTTTCAAACCG
TTATGCTGTTCCTTACCTTT

Product: Beta-glucosidase

Products: NA

Alternate protein names: Amygdalase; Beta-D-glucoside glucohydrolase; Cellobiase; Gentiobiase [H]

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MKISLPKNSRLQSEAFTFGVATASFQIEGGVDSRQTCIWDTFCATPDKIRDASNGDIACNHLNLWQEDIALITSLGVDAY
RFSIAWGRVLNQDGSINQQGVDFYIGILDELKRRNIKAFVTLYHWDLPQHIEDQGGWLNRDTAYLFKDYADKISQAFGDR
VYSYATLNEPFCSSYLGYEAGIHAPGLMKKAYGRQSAHHLLLAHGLAMQVLQKNSPNSMNGIVLNFTPCYALTQSAADIQ
AAKQADDYFNQWYIKPIFDAAYPDLLAALAPEDRPEIHDGDLELISQPIDFLGVNFYTRAVYQADAEQGFVQVDLPGVPK
TDIGWEIHPQAFTDLLVSLNQTYDLPPIFITENGAAMDDKCIDGRVDDFDRLSYYQHHLTAVDNAIVQGVNIQGYFAWSL
MDNFEWAEGYLKRFGIVYVDYASQTRTIKASGQAYSDLIRSRAHFTNNNNK

Sequences:

>Translated_451_residues
MKISLPKNSRLQSEAFTFGVATASFQIEGGVDSRQTCIWDTFCATPDKIRDASNGDIACNHLNLWQEDIALITSLGVDAY
RFSIAWGRVLNQDGSINQQGVDFYIGILDELKRRNIKAFVTLYHWDLPQHIEDQGGWLNRDTAYLFKDYADKISQAFGDR
VYSYATLNEPFCSSYLGYEAGIHAPGLMKKAYGRQSAHHLLLAHGLAMQVLQKNSPNSMNGIVLNFTPCYALTQSAADIQ
AAKQADDYFNQWYIKPIFDAAYPDLLAALAPEDRPEIHDGDLELISQPIDFLGVNFYTRAVYQADAEQGFVQVDLPGVPK
TDIGWEIHPQAFTDLLVSLNQTYDLPPIFITENGAAMDDKCIDGRVDDFDRLSYYQHHLTAVDNAIVQGVNIQGYFAWSL
MDNFEWAEGYLKRFGIVYVDYASQTRTIKASGQAYSDLIRSRAHFTNNNNK
>Mature_451_residues
MKISLPKNSRLQSEAFTFGVATASFQIEGGVDSRQTCIWDTFCATPDKIRDASNGDIACNHLNLWQEDIALITSLGVDAY
RFSIAWGRVLNQDGSINQQGVDFYIGILDELKRRNIKAFVTLYHWDLPQHIEDQGGWLNRDTAYLFKDYADKISQAFGDR
VYSYATLNEPFCSSYLGYEAGIHAPGLMKKAYGRQSAHHLLLAHGLAMQVLQKNSPNSMNGIVLNFTPCYALTQSAADIQ
AAKQADDYFNQWYIKPIFDAAYPDLLAALAPEDRPEIHDGDLELISQPIDFLGVNFYTRAVYQADAEQGFVQVDLPGVPK
TDIGWEIHPQAFTDLLVSLNQTYDLPPIFITENGAAMDDKCIDGRVDDFDRLSYYQHHLTAVDNAIVQGVNIQGYFAWSL
MDNFEWAEGYLKRFGIVYVDYASQTRTIKASGQAYSDLIRSRAHFTNNNNK

Specific function: Can Hydrolyze Salicin, Cellobiose, And Probably Arbutin. [C]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=462, Percent_Identity=32.9004329004329, Blast_Score=249, Evalue=3e-66,
Organism=Homo sapiens, GI13273313, Length=462, Percent_Identity=34.8484848484849, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI110681710, Length=461, Percent_Identity=32.3210412147505, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI24497614, Length=458, Percent_Identity=31.0043668122271, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI28376633, Length=452, Percent_Identity=28.0973451327434, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI190360571, Length=131, Percent_Identity=32.824427480916, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI1789070, Length=412, Percent_Identity=30.5825242718447, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI2367270, Length=466, Percent_Identity=28.755364806867, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI2367174, Length=488, Percent_Identity=27.6639344262295, Blast_Score=156, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17552856, Length=482, Percent_Identity=32.9875518672199, Blast_Score=222, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI17539390, Length=484, Percent_Identity=33.2644628099174, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI21356577, Length=470, Percent_Identity=32.5531914893617, Blast_Score=245, Evalue=6e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017736
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.21 [H]

Molecular weight: Translated: 50780; Mature: 50780

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISLPKNSRLQSEAFTFGVATASFQIEGGVDSRQTCIWDTFCATPDKIRDASNGDIACN
CEECCCCCCCCCHHHEEEEEEEEEEEEECCCCCCCEEEEEHHCCCHHHHCCCCCCCEEEE
HLNLWQEDIALITSLGVDAYRFSIAWGRVLNQDGSINQQGVDFYIGILDELKRRNIKAFV
CCHHHHHHHHHHHHCCCCCEEEEEEHHHHHCCCCCCCCCCCHHEEEHHHHHHHCCEEEEE
TLYHWDLPQHIEDQGGWLNRDTAYLFKDYADKISQAFGDRVYSYATLNEPFCSSYLGYEA
EEEECCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHCCCCC
GIHAPGLMKKAYGRQSAHHLLLAHGLAMQVLQKNSPNSMNGIVLNFTPCYALTQSAADIQ
CCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHH
AAKQADDYFNQWYIKPIFDAAYPDLLAALAPEDRPEIHDGDLELISQPIDFLGVNFYTRA
HHHHHHHHHHHEEECHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHHCCHHHHHH
VYQADAEQGFVQVDLPGVPKTDIGWEIHPQAFTDLLVSLNQTYDLPPIFITENGAAMDDK
HHHHHHHCCEEEEECCCCCCCCCCCEECHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
CIDGRVDDFDRLSYYQHHLTAVDNAIVQGVNIQGYFAWSLMDNFEWAEGYLKRFGIVYVD
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCEEEEE
YASQTRTIKASGQAYSDLIRSRAHFTNNNNK
ECCCCEEEEECCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKISLPKNSRLQSEAFTFGVATASFQIEGGVDSRQTCIWDTFCATPDKIRDASNGDIACN
CEECCCCCCCCCHHHEEEEEEEEEEEEECCCCCCCEEEEEHHCCCHHHHCCCCCCCEEEE
HLNLWQEDIALITSLGVDAYRFSIAWGRVLNQDGSINQQGVDFYIGILDELKRRNIKAFV
CCHHHHHHHHHHHHCCCCCEEEEEEHHHHHCCCCCCCCCCCHHEEEHHHHHHHCCEEEEE
TLYHWDLPQHIEDQGGWLNRDTAYLFKDYADKISQAFGDRVYSYATLNEPFCSSYLGYEA
EEEECCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHCCCCC
GIHAPGLMKKAYGRQSAHHLLLAHGLAMQVLQKNSPNSMNGIVLNFTPCYALTQSAADIQ
CCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHH
AAKQADDYFNQWYIKPIFDAAYPDLLAALAPEDRPEIHDGDLELISQPIDFLGVNFYTRA
HHHHHHHHHHHEEECHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHHCCHHHHHH
VYQADAEQGFVQVDLPGVPKTDIGWEIHPQAFTDLLVSLNQTYDLPPIFITENGAAMDDK
HHHHHHHCCEEEEECCCCCCCCCCCEECHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
CIDGRVDDFDRLSYYQHHLTAVDNAIVQGVNIQGYFAWSLMDNFEWAEGYLKRFGIVYVD
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCEEEEE
YASQTRTIKASGQAYSDLIRSRAHFTNNNNK
ECCCCEEEEECCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2123813 [H]