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The map label for this gene is yiaV [H]

Identifier: 126173235

GI number: 126173235

Start: 1137554

End: 1138699

Strand: Direct

Name: yiaV [H]

Synonym: Sbal_0991

Alternate gene names: 126173235

Gene position: 1137554-1138699 (Clockwise)

Preceding gene: 126173234

Following gene: 126173236

Centisome position: 22.19

GC content: 47.21

Gene sequence:

>1146_bases
ATGGATCTATTGCTGATATTGACCTACGCCGCTATCTGTATTGTTATTTTTAAAGTCTTTAAAATCCCTCTGACCAAATG
GACGGTTCCTACTGCCGTTTTGGGGGGCGTGGTGCTCATCGGTGCCTTGATACTGCTAATGAACTATAACCATCCCTATT
CACGTTTTGCTCGGGAATATTTTGTCACCATTCCGATTACACCCGCAGTAAAAGGGTTAGTTAGTCGTGTTGAAGTGCAG
CCAAATACTCCTGTTAAACAAGGGGATGTACTTTTTCGGATTGATCCCATCCCCTTTGAGGCCGTAGTAAAGCGTAAGCG
TGCCGCGTTAGTCGCTGCCGAGTTAGAAGTGCCACAGCTCGCCGCCGCATTGGAATCGGCTAAAGCTAATGTTGAGCGAG
TCAATGCTGATAAAGATCGCAATAAATCCGTCTATGAACGCTATGAAAGCGGTCATCGAAAAGGAGGCGCTAACTCTCCC
TTTACCGCATTAGAATTGGATAATAAACGCCAACTGTATCTTGCCTCTGAAGCGCAGTTAACTGCCGCTAGATCAGAAGA
GTTACGGATGAGGCTCGCCTATGAGTCTAATATTGATGGCGTTAATACCAAAGTGGCTGGCTTACAGGGAGATTTAGCGA
GCGCACTCTATGATTTAAAGCAGACCGTCGTGCGAGCACCCGCAGACGGTATCGTCACGCAAATGGCACTCCGTCCGGGG
GCTATGGCTGTACCTTTACCATTACGTCCCGTGATGAGCTTTATCCCTGACGAGCAACGTTATTTTGCCGGAGCCTTTTG
GCAGAATTCCCTACTGCGCCTGAAAGAAGGCGATGAGGCCGAGATTATTCTCGATGCCGCGCCAGGGAAAGTGTTTAAAG
GCAAAGTGGCGAAAGTGCTACCCGCAATGGCTGAAGGTGAGATCCAAATGGGTGGCGTATTAGCGTCCTCCAGTCGTCTG
TTTCAAAATGGTCGAGTGGTTGTTCTTATCGATATAGATGACGATGCTATTCGTAAAGAGTTCCCTGCTGGAGTGTCAGG
TCAAGTTGCTATTTACACTGAGCACTTTCATCATGTAGCTGTAATGCGTAAGGTATTACTCAGGATGCAAGGGTGGTTGA
ATTACTTATTTTTTGATGGACATTAG

Upstream 100 bases:

>100_bases
CGTCAGACGGTAATAGCGTTACAAGCGAGACTTGAGCAATTAGAGCAAGCAAGCGCAACTGTTGTTGAGCCGAACATTAT
CAATAAAGTCGAGGTCTAAA

Downstream 100 bases:

>100_bases
TACCTAAACCGTTAAATCTTGTTTGTTGAGTACTTTGTTCAGTTCTGTGCAAAGGTTGGTATAAAGTCCAGTTCGCTGGA
CTTTTTTGTGGCAATTTTTA

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MDLLLILTYAAICIVIFKVFKIPLTKWTVPTAVLGGVVLIGALILLMNYNHPYSRFAREYFVTIPITPAVKGLVSRVEVQ
PNTPVKQGDVLFRIDPIPFEAVVKRKRAALVAAELEVPQLAAALESAKANVERVNADKDRNKSVYERYESGHRKGGANSP
FTALELDNKRQLYLASEAQLTAARSEELRMRLAYESNIDGVNTKVAGLQGDLASALYDLKQTVVRAPADGIVTQMALRPG
AMAVPLPLRPVMSFIPDEQRYFAGAFWQNSLLRLKEGDEAEIILDAAPGKVFKGKVAKVLPAMAEGEIQMGGVLASSSRL
FQNGRVVVLIDIDDDAIRKEFPAGVSGQVAIYTEHFHHVAVMRKVLLRMQGWLNYLFFDGH

Sequences:

>Translated_381_residues
MDLLLILTYAAICIVIFKVFKIPLTKWTVPTAVLGGVVLIGALILLMNYNHPYSRFAREYFVTIPITPAVKGLVSRVEVQ
PNTPVKQGDVLFRIDPIPFEAVVKRKRAALVAAELEVPQLAAALESAKANVERVNADKDRNKSVYERYESGHRKGGANSP
FTALELDNKRQLYLASEAQLTAARSEELRMRLAYESNIDGVNTKVAGLQGDLASALYDLKQTVVRAPADGIVTQMALRPG
AMAVPLPLRPVMSFIPDEQRYFAGAFWQNSLLRLKEGDEAEIILDAAPGKVFKGKVAKVLPAMAEGEIQMGGVLASSSRL
FQNGRVVVLIDIDDDAIRKEFPAGVSGQVAIYTEHFHHVAVMRKVLLRMQGWLNYLFFDGH
>Mature_381_residues
MDLLLILTYAAICIVIFKVFKIPLTKWTVPTAVLGGVVLIGALILLMNYNHPYSRFAREYFVTIPITPAVKGLVSRVEVQ
PNTPVKQGDVLFRIDPIPFEAVVKRKRAALVAAELEVPQLAAALESAKANVERVNADKDRNKSVYERYESGHRKGGANSP
FTALELDNKRQLYLASEAQLTAARSEELRMRLAYESNIDGVNTKVAGLQGDLASALYDLKQTVVRAPADGIVTQMALRPG
AMAVPLPLRPVMSFIPDEQRYFAGAFWQNSLLRLKEGDEAEIILDAAPGKVFKGKVAKVLPAMAEGEIQMGGVLASSSRL
FQNGRVVVLIDIDDDAIRKEFPAGVSGQVAIYTEHFHHVAVMRKVLLRMQGWLNYLFFDGH

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790012, Length=379, Percent_Identity=45.1187335092348, Blast_Score=350, Evalue=1e-97,
Organism=Escherichia coli, GI1790024, Length=379, Percent_Identity=43.7994722955145, Blast_Score=345, Evalue=4e-96,
Organism=Escherichia coli, GI1790519, Length=261, Percent_Identity=28.735632183908, Blast_Score=92, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42028; Mature: 42028

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLLILTYAAICIVIFKVFKIPLTKWTVPTAVLGGVVLIGALILLMNYNHPYSRFAREY
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHE
FVTIPITPAVKGLVSRVEVQPNTPVKQGDVLFRIDPIPFEAVVKRKRAALVAAELEVPQL
EEEEECCHHHHHHHHHEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHEEECCCHHHH
AAALESAKANVERVNADKDRNKSVYERYESGHRKGGANSPFTALELDNKRQLYLASEAQL
HHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEECCCHH
TAARSEELRMRLAYESNIDGVNTKVAGLQGDLASALYDLKQTVVRAPADGIVTQMALRPG
HHHCCHHHEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
AMAVPLPLRPVMSFIPDEQRYFAGAFWQNSLLRLKEGDEAEIILDAAPGKVFKGKVAKVL
CEECCCCHHHHHHHCCCCHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCHHCHHHHHH
PAMAEGEIQMGGVLASSSRLFQNGRVVVLIDIDDDAIRKEFPAGVSGQVAIYTEHFHHVA
HHHHCCCEEECCEEECCHHHHHCCCEEEEEECCCHHHHHHCCCCCCCEEEEEHHHHHHHH
VMRKVLLRMQGWLNYLFFDGH
HHHHHHHHHHHHHEEEEECCC
>Mature Secondary Structure
MDLLLILTYAAICIVIFKVFKIPLTKWTVPTAVLGGVVLIGALILLMNYNHPYSRFAREY
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHE
FVTIPITPAVKGLVSRVEVQPNTPVKQGDVLFRIDPIPFEAVVKRKRAALVAAELEVPQL
EEEEECCHHHHHHHHHEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHEEECCCHHHH
AAALESAKANVERVNADKDRNKSVYERYESGHRKGGANSPFTALELDNKRQLYLASEAQL
HHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEECCCHH
TAARSEELRMRLAYESNIDGVNTKVAGLQGDLASALYDLKQTVVRAPADGIVTQMALRPG
HHHCCHHHEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
AMAVPLPLRPVMSFIPDEQRYFAGAFWQNSLLRLKEGDEAEIILDAAPGKVFKGKVAKVL
CEECCCCHHHHHHHCCCCHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCHHCHHHHHH
PAMAEGEIQMGGVLASSSRLFQNGRVVVLIDIDDDAIRKEFPAGVSGQVAIYTEHFHHVA
HHHHCCCEEECCEEECCHHHHHCCCEEEEEECCCHHHHHHCCCCCCCEEEEEHHHHHHHH
VMRKVLLRMQGWLNYLFFDGH
HHHHHHHHHHHHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]