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The map label for this gene is hlyB [H]

Identifier: 126173179

GI number: 126173179

Start: 1071383

End: 1073386

Strand: Direct

Name: hlyB [H]

Synonym: Sbal_0934

Alternate gene names: 126173179

Gene position: 1071383-1073386 (Clockwise)

Preceding gene: 126173178

Following gene: 126173180

Centisome position: 20.9

GC content: 49.65

Gene sequence:

>2004_bases
ATGGGATATATGAAACGTTCTCTAAGTTTGCAGTTAGTGGTTACTATCGTTGGTGCGCTTGCTGTACTGCTTACCTTAGT
CGCCGCTTTGTTGGTGACGAAAGAAAGTGATAACACGCGAAAGCAGGTCGATGCGGATATTTCGGCTTTAGTTGCCTTAA
AAGCCAATGAGATTAGCGGTTACTTTATTGCTAAGGGCCAAGTGATCCATTCAGTGTTTGCCGAGCCGGGTTTAGTGAAG
TGGTTTACTCAGTATCACGCCCGTGGCAGTCACCTCGCGGCTGATCGCCAGTACCAAGACATTATTGGTTACTTTAAGTC
TTTCTCTGATCGCGATAGTGATGTTAAATCGGTGTTTTTTGGCTCGGCCAATACCTTCGAGTACTTTGACCTTAATGGCC
GTTTTGATGGCGATCCAGATTACTACACCAACAAACGACCTTGGTGGCAGGAAGCGATCGATCAAGCCGGGCTCTTTGTT
GGCGATCCAGCGGTCGATGCGAACGATGGTTCAATTTCTGCCACGGTTAAAACCCCCGTTTATGCGGCGAATGGCGAGCT
GATTGGTATCGGCGGCATGGATATCTTGATTGATACTATTGGTAAATCCCTGCTGGCACCGATTAAATACCGTGATTTTG
GCCAAGCTTTCTTAATGACAGACGAAGGCAAGCTAGTGTATTTCCCTGGTTTTTCCGAGCGTTTCCCGCCGGGCTCCTTG
GCGAATCAAGTGGATACTCAGTTTAAGGACACATCAGGATTTTCTGCATTACGACAACAGATGCAAAGGGAAGCGCAAGG
GTTTGCTAATGTTACTTTTAATGGTGTGCCCCAGCGGGTGAGCTTTGTGACTGTGGGCGGCGATTATCCCAAACAAAAGT
GGCACTTAGCCTTTATGTTGCCTCACGAAGTGATTGAAGCGCCAGTGACCGCCGCGTTCTGGAATGCCAGTATGGTCGCC
ATAGGTATCATGCTGCTAATGGGCGTGACCGTATGGTTGATGTTGCTGCCCTTTAGACGCCAATTAGCTAAGTTATTGGA
TGCGATGGAAGATATCGCCGAAGGTGACAGTGATTTATCAAAACGTATTCTGATGGATCGGGAAGATGAGTTAGGCAAAC
TTGGCGATGCCTTTAACCGCTTTGCCGAGAAAGTGCAGCACATGCTGTTGGATACACGCAGCTTAACCCAAGAGGTTGGC
ACGGGCGTTATTGATGCGCGGCAGATTTGCGATTTAGCCGTGTCGTCGGTCTCATCGCAGAAGCAGCAGATAGATTCGGT
TGCTACCGCTGCAACGCAAATGGCGCAAACCAGTCAAGAAATGGCTGTCAGTGCCCAGAGGGCGAATGATTTTGCTCAGA
AGGCGCAAACTCAAGCCTACGATGGTACACAGATTGTTTCCCGTGCGACCGAAGGGATGAAGGCACTGTCGCAACAAGTG
ATTGCGGCGGCGAAAGTGATTAAACACTTACGCAATAGCTCAGAGCAAATCGGTGAAGTCTTGAGCGTGATCCGTAACAT
TGCCGAGCAAACTAATCTATTAGCCCTTAACGCAGCAATTGAAGCGGCGCGTGCGGGTGAGCAAGGCCGTGGCTTTGCTG
TGGTGGCAGACGAAGTGCGCACGTTGGCATCGCGTACCCAAGATTCTACCGCTAACATTCAAGGCATTATCCAAACCTTG
CAACAAAGCGCATTGCAGGCTGAGCAAGTGATGGAATCGGGCGTTGAGCAAGCGAAAGCGGGGCAAGAGCTAACGACTCA
GGTCGAAGCGGCACTGAATGATATTGCGACGGCGATTATGTCAATCCAACAGCAAACGGTTGAAATAACCGTAGCAATCG
ATCAGCAAGCCGTGGCGGCCGAGGAAGTGGCGCTCAATGTCGATAATGTGCGGGGGTTGTCGGATCAGTCTTTGCTTTCG
AGTCAGGACTTGTCGCAAAGCTTGCAAGGCTTTGAGGATATGACCCGCGCGCTCACACGCAATATCGGCCAATTTAAGAT
TTAA

Upstream 100 bases:

>100_bases
GGCGATTTCATCTGTTGTTAACAGGTAAAAATTGTTACCGTGTAAAACTATTTTTGCGAGCCATATTGTTAAGTTGTTGG
TCAGCCAGACGGGAAGATTG

Downstream 100 bases:

>100_bases
GCCTGAGTTGGTCAGTGAACTGTTTGCTCACTGACCATCAGCTCAATCACGGCATCACTCATAGTGCACTCACAAAAGGA
GCTTAGGCTCCTTTTTATTT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 667; Mature: 666

Protein sequence:

>667_residues
MGYMKRSLSLQLVVTIVGALAVLLTLVAALLVTKESDNTRKQVDADISALVALKANEISGYFIAKGQVIHSVFAEPGLVK
WFTQYHARGSHLAADRQYQDIIGYFKSFSDRDSDVKSVFFGSANTFEYFDLNGRFDGDPDYYTNKRPWWQEAIDQAGLFV
GDPAVDANDGSISATVKTPVYAANGELIGIGGMDILIDTIGKSLLAPIKYRDFGQAFLMTDEGKLVYFPGFSERFPPGSL
ANQVDTQFKDTSGFSALRQQMQREAQGFANVTFNGVPQRVSFVTVGGDYPKQKWHLAFMLPHEVIEAPVTAAFWNASMVA
IGIMLLMGVTVWLMLLPFRRQLAKLLDAMEDIAEGDSDLSKRILMDREDELGKLGDAFNRFAEKVQHMLLDTRSLTQEVG
TGVIDARQICDLAVSSVSSQKQQIDSVATAATQMAQTSQEMAVSAQRANDFAQKAQTQAYDGTQIVSRATEGMKALSQQV
IAAAKVIKHLRNSSEQIGEVLSVIRNIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQDSTANIQGIIQTL
QQSALQAEQVMESGVEQAKAGQELTTQVEAALNDIATAIMSIQQQTVEITVAIDQQAVAAEEVALNVDNVRGLSDQSLLS
SQDLSQSLQGFEDMTRALTRNIGQFKI

Sequences:

>Translated_667_residues
MGYMKRSLSLQLVVTIVGALAVLLTLVAALLVTKESDNTRKQVDADISALVALKANEISGYFIAKGQVIHSVFAEPGLVK
WFTQYHARGSHLAADRQYQDIIGYFKSFSDRDSDVKSVFFGSANTFEYFDLNGRFDGDPDYYTNKRPWWQEAIDQAGLFV
GDPAVDANDGSISATVKTPVYAANGELIGIGGMDILIDTIGKSLLAPIKYRDFGQAFLMTDEGKLVYFPGFSERFPPGSL
ANQVDTQFKDTSGFSALRQQMQREAQGFANVTFNGVPQRVSFVTVGGDYPKQKWHLAFMLPHEVIEAPVTAAFWNASMVA
IGIMLLMGVTVWLMLLPFRRQLAKLLDAMEDIAEGDSDLSKRILMDREDELGKLGDAFNRFAEKVQHMLLDTRSLTQEVG
TGVIDARQICDLAVSSVSSQKQQIDSVATAATQMAQTSQEMAVSAQRANDFAQKAQTQAYDGTQIVSRATEGMKALSQQV
IAAAKVIKHLRNSSEQIGEVLSVIRNIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQDSTANIQGIIQTL
QQSALQAEQVMESGVEQAKAGQELTTQVEAALNDIATAIMSIQQQTVEITVAIDQQAVAAEEVALNVDNVRGLSDQSLLS
SQDLSQSLQGFEDMTRALTRNIGQFKI
>Mature_666_residues
GYMKRSLSLQLVVTIVGALAVLLTLVAALLVTKESDNTRKQVDADISALVALKANEISGYFIAKGQVIHSVFAEPGLVKW
FTQYHARGSHLAADRQYQDIIGYFKSFSDRDSDVKSVFFGSANTFEYFDLNGRFDGDPDYYTNKRPWWQEAIDQAGLFVG
DPAVDANDGSISATVKTPVYAANGELIGIGGMDILIDTIGKSLLAPIKYRDFGQAFLMTDEGKLVYFPGFSERFPPGSLA
NQVDTQFKDTSGFSALRQQMQREAQGFANVTFNGVPQRVSFVTVGGDYPKQKWHLAFMLPHEVIEAPVTAAFWNASMVAI
GIMLLMGVTVWLMLLPFRRQLAKLLDAMEDIAEGDSDLSKRILMDREDELGKLGDAFNRFAEKVQHMLLDTRSLTQEVGT
GVIDARQICDLAVSSVSSQKQQIDSVATAATQMAQTSQEMAVSAQRANDFAQKAQTQAYDGTQIVSRATEGMKALSQQVI
AAAKVIKHLRNSSEQIGEVLSVIRNIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQDSTANIQGIIQTLQ
QSALQAEQVMESGVEQAKAGQELTTQVEAALNDIATAIMSIQQQTVEITVAIDQQAVAAEEVALNVDNVRGLSDQSLLSS
QDLSQSLQGFEDMTRALTRNIGQFKI

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=365, Percent_Identity=31.7808219178082, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI2367378, Length=344, Percent_Identity=27.6162790697674, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788195, Length=316, Percent_Identity=32.5949367088608, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI1788194, Length=354, Percent_Identity=27.683615819209, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1789453, Length=331, Percent_Identity=28.0966767371601, Blast_Score=93, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 72704; Mature: 72573

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYMKRSLSLQLVVTIVGALAVLLTLVAALLVTKESDNTRKQVDADISALVALKANEISG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEECCCCC
YFIAKGQVIHSVFAEPGLVKWFTQYHARGSHLAADRQYQDIIGYFKSFSDRDSDVKSVFF
EEEECHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHC
GSANTFEYFDLNGRFDGDPDYYTNKRPWWQEAIDQAGLFVGDPAVDANDGSISATVKTPV
CCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCEECCCCCCCCCCCEEEEEECCE
YAANGELIGIGGMDILIDTIGKSLLAPIKYRDFGQAFLMTDEGKLVYFPGFSERFPPGSL
EECCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCHH
ANQVDTQFKDTSGFSALRQQMQREAQGFANVTFNGVPQRVSFVTVGGDYPKQKWHLAFML
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEECCCCCEEEEEEECCCCCCCCEEEEEEC
PHEVIEAPVTAAFWNASMVAIGIMLLMGVTVWLMLLPFRRQLAKLLDAMEDIAEGDSDLS
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
KRILMDREDELGKLGDAFNRFAEKVQHMLLDTRSLTQEVGTGVIDARQICDLAVSSVSSQ
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KQQIDSVATAATQMAQTSQEMAVSAQRANDFAQKAQTQAYDGTQIVSRATEGMKALSQQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
IAAAKVIKHLRNSSEQIGEVLSVIRNIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVR
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCEEEHHHHHHHHHCCCCCCCEEEEHHHHH
TLASRTQDSTANIQGIIQTLQQSALQAEQVMESGVEQAKAGQELTTQVEAALNDIATAIM
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
SIQQQTVEITVAIDQQAVAAEEVALNVDNVRGLSDQSLLSSQDLSQSLQGFEDMTRALTR
HHHHHEEEEEEEECCHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NIGQFKI
CCCCCCC
>Mature Secondary Structure 
GYMKRSLSLQLVVTIVGALAVLLTLVAALLVTKESDNTRKQVDADISALVALKANEISG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEECCCCC
YFIAKGQVIHSVFAEPGLVKWFTQYHARGSHLAADRQYQDIIGYFKSFSDRDSDVKSVFF
EEEECHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHC
GSANTFEYFDLNGRFDGDPDYYTNKRPWWQEAIDQAGLFVGDPAVDANDGSISATVKTPV
CCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCEECCCCCCCCCCCEEEEEECCE
YAANGELIGIGGMDILIDTIGKSLLAPIKYRDFGQAFLMTDEGKLVYFPGFSERFPPGSL
EECCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCHH
ANQVDTQFKDTSGFSALRQQMQREAQGFANVTFNGVPQRVSFVTVGGDYPKQKWHLAFML
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEECCCCCEEEEEEECCCCCCCCEEEEEEC
PHEVIEAPVTAAFWNASMVAIGIMLLMGVTVWLMLLPFRRQLAKLLDAMEDIAEGDSDLS
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
KRILMDREDELGKLGDAFNRFAEKVQHMLLDTRSLTQEVGTGVIDARQICDLAVSSVSSQ
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KQQIDSVATAATQMAQTSQEMAVSAQRANDFAQKAQTQAYDGTQIVSRATEGMKALSQQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
IAAAKVIKHLRNSSEQIGEVLSVIRNIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVR
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCEEEHHHHHHHHHCCCCCCCEEEEHHHHH
TLASRTQDSTANIQGIIQTLQQSALQAEQVMESGVEQAKAGQELTTQVEAALNDIATAIM
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
SIQQQTVEITVAIDQQAVAAEEVALNVDNVRGLSDQSLLSSQDLSQSLQGFEDMTRALTR
HHHHHEEEEEEEECCHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NIGQFKI
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]