Click here to switch to the map view.

The map label for this gene is dinB

Identifier: 126173180

GI number: 126173180

Start: 1073576

End: 1074652

Strand: Direct

Name: dinB

Synonym: Sbal_0935

Alternate gene names: 126173180

Gene position: 1073576-1074652 (Clockwise)

Preceding gene: 126173179

Following gene: 126173181

Centisome position: 20.94

GC content: 49.58

Gene sequence:

>1077_bases
GTGCGAAAAATTATTCACATCGATATGGACTGCTATTTTGCGGCAGTGGAAATGCGCGACTTTCCCGAATACCGTGGCAA
GCCTTTAGCTGTGGGCGGCAGCAGCGATCGTCGTGGTGTTATTAGCACTTGTAGCTACGAGGCACGTAAATTCGGTGTGC
GTTCAGCGATGGCGACCGCTTATGCCTTTAAGTTGTGTCCCGATCTCATTTTGGTTCCTGGGCGGATGCAAGTTTATAAA
GATGTGTCGCTGCAAATTCGTGAAATCTTCTCCCGTTATACCCAATTGGTTGAGCCGTTGTCCTTAGATGAAGCCTATTT
AGACGTGAGTGAGTGCCAACAATATAAGGGCTCGGCGACCTTGATTGCGCAGGCCATTCGCCGCGATATCTTAGCCGAAA
CTGGGTTAACCGCTTCGGCTGGCATAGCCCCTGTGAAGTTTTTGGCTAAGGTTGCCTCTGATCTGAATAAGCCAAACGGC
CAATATGTGATTACCCCAGAGACACTCCCTGAGTTTGTTAAAACCTTATCGCTGCGTAAAATTCCCGGTGTCGGCAAAGT
CACCGCCGAAAAGCTCTCCTCGCTTGGGCTCAATACCTGTGGTGATGTGCAAGCCTACTCTAAACCTGAGTTATTGGCGC
GATTCGGAAAATTTGGTGGCGTGTTGATTGAGCGTTCCCAAGGCATCGATGAGCGGGGCATTTCCGCTGACAGGGAGCGT
AAATCAGTCGGTGTTGAAACCACGCTGGCGAAGGATATTTATAGCTTAGAGCAGTGCCAACAAGTAATGCCGGGGTTGAT
CCAAGAATTAGCCCTACGTTTGAGTCGCAGCGCTAAGGAACGCAAAATTCACAAGCAAGTCGTCAAACTCAAGTTTAATG
ATTTCAAGCAAACCACCATTGAGCATCGCAGCGATGAAGTCTCGATTGTGATGTTTTATGATCTACTCGCACAAGCGATG
GCAAGGCAAGAGGGCCGCGGCATTCGCCTATTAGGTATTTCGGTCGGCCTCGCCGATTCTATCCTCGCAGTGTCCGAAAT
CCCAAATGCCCAGACTCAGCTTGATTTAGCGCTCTAG

Upstream 100 bases:

>100_bases
CCTTTTTATTTTAGGTTTCCCGCCTGATCCTCGCTAAATTGATGATGAATACTTGATTACTGTTTTTATATACAGTATTT
TGGCGTTGGAGGAATTCAAC

Downstream 100 bases:

>100_bases
GCGTTTATTGAGTCGATACGCCGCAGACTCATGCCTGAATGGCTCAATAAGCCTCGGGTGGATTCGCCAACATAAAATCA
ATTAACAGTCTGACCCGCAA

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSSDRRGVISTCSYEARKFGVRSAMATAYAFKLCPDLILVPGRMQVYK
DVSLQIREIFSRYTQLVEPLSLDEAYLDVSECQQYKGSATLIAQAIRRDILAETGLTASAGIAPVKFLAKVASDLNKPNG
QYVITPETLPEFVKTLSLRKIPGVGKVTAEKLSSLGLNTCGDVQAYSKPELLARFGKFGGVLIERSQGIDERGISADRER
KSVGVETTLAKDIYSLEQCQQVMPGLIQELALRLSRSAKERKIHKQVVKLKFNDFKQTTIEHRSDEVSIVMFYDLLAQAM
ARQEGRGIRLLGISVGLADSILAVSEIPNAQTQLDLAL

Sequences:

>Translated_358_residues
MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSSDRRGVISTCSYEARKFGVRSAMATAYAFKLCPDLILVPGRMQVYK
DVSLQIREIFSRYTQLVEPLSLDEAYLDVSECQQYKGSATLIAQAIRRDILAETGLTASAGIAPVKFLAKVASDLNKPNG
QYVITPETLPEFVKTLSLRKIPGVGKVTAEKLSSLGLNTCGDVQAYSKPELLARFGKFGGVLIERSQGIDERGISADRER
KSVGVETTLAKDIYSLEQCQQVMPGLIQELALRLSRSAKERKIHKQVVKLKFNDFKQTTIEHRSDEVSIVMFYDLLAQAM
ARQEGRGIRLLGISVGLADSILAVSEIPNAQTQLDLAL
>Mature_358_residues
MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSSDRRGVISTCSYEARKFGVRSAMATAYAFKLCPDLILVPGRMQVYK
DVSLQIREIFSRYTQLVEPLSLDEAYLDVSECQQYKGSATLIAQAIRRDILAETGLTASAGIAPVKFLAKVASDLNKPNG
QYVITPETLPEFVKTLSLRKIPGVGKVTAEKLSSLGLNTCGDVQAYSKPELLARFGKFGGVLIERSQGIDERGISADRER
KSVGVETTLAKDIYSLEQCQQVMPGLIQELALRLSRSAKERKIHKQVVKLKFNDFKQTTIEHRSDEVSIVMFYDLLAQAM
ARQEGRGIRLLGISVGLADSILAVSEIPNAQTQLDLAL

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain

Homologues:

Organism=Homo sapiens, GI7706681, Length=325, Percent_Identity=31.0769230769231, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI84043967, Length=324, Percent_Identity=31.1728395061728, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI154350220, Length=249, Percent_Identity=32.9317269076305, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI7705344, Length=108, Percent_Identity=49.0740740740741, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI5729982, Length=141, Percent_Identity=39.7163120567376, Blast_Score=89, Evalue=8e-18,
Organism=Escherichia coli, GI1786425, Length=362, Percent_Identity=58.0110497237569, Blast_Score=406, Evalue=1e-114,
Organism=Escherichia coli, GI1787432, Length=207, Percent_Identity=25.6038647342995, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17537959, Length=282, Percent_Identity=29.7872340425532, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI193205700, Length=394, Percent_Identity=28.9340101522843, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI115534089, Length=359, Percent_Identity=25.0696378830084, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI193205702, Length=206, Percent_Identity=31.5533980582524, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324921, Length=207, Percent_Identity=29.4685990338164, Blast_Score=79, Evalue=8e-16,
Organism=Drosophila melanogaster, GI19923006, Length=323, Percent_Identity=30.030959752322, Blast_Score=160, Evalue=9e-40,
Organism=Drosophila melanogaster, GI21355641, Length=284, Percent_Identity=29.9295774647887, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24644984, Length=284, Percent_Identity=29.9295774647887, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24668444, Length=123, Percent_Identity=38.2113821138211, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO4_SHEB5 (A3D147)

Other databases:

- EMBL:   CP000563
- RefSeq:   YP_001049329.1
- ProteinModelPortal:   A3D147
- SMR:   A3D147
- STRING:   A3D147
- GeneID:   4841437
- GenomeReviews:   CP000563_GR
- KEGG:   sbl:Sbal_0935
- NMPDR:   fig|325240.3.peg.1067
- eggNOG:   COG0389
- HOGENOM:   HBG734504
- OMA:   QAMARQE
- PhylomeDB:   A3D147
- ProtClustDB:   PRK02406
- GO:   GO:0005737
- HAMAP:   MF_01113
- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880
- Gene3D:   G3DSA:3.30.1490.100
- PANTHER:   PTHR11076

Pfam domain/function: PF00817 IMS; SSF100879 DNA_pol_Y-fam_little_finger

EC number: =2.7.7.7

Molecular weight: Translated: 39588; Mature: 39588

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS50173 UMUC

Important sites: ACT_SITE 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSSDRRGVISTCSYEARKFGVRSAMATA
CCEEEEECCHHHEEHHHHHHCHHHCCCEEEECCCCCCCCCHHHCCHHHHHHHHHHHHHHH
YAFKLCPDLILVPGRMQVYKDVSLQIREIFSRYTQLVEPLSLDEAYLDVSECQQYKGSAT
HHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHCCCHHH
LIAQAIRRDILAETGLTASAGIAPVKFLAKVASDLNKPNGQYVITPETLPEFVKTLSLRK
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHC
IPGVGKVTAEKLSSLGLNTCGDVQAYSKPELLARFGKFGGVLIERSQGIDERGISADRER
CCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHH
KSVGVETTLAKDIYSLEQCQQVMPGLIQELALRLSRSAKERKIHKQVVKLKFNDFKQTTI
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHRSDEVSIVMFYDLLAQAMARQEGRGIRLLGISVGLADSILAVSEIPNAQTQLDLAL
HCCCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHCCCCHHHEEECC
>Mature Secondary Structure
MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSSDRRGVISTCSYEARKFGVRSAMATA
CCEEEEECCHHHEEHHHHHHCHHHCCCEEEECCCCCCCCCHHHCCHHHHHHHHHHHHHHH
YAFKLCPDLILVPGRMQVYKDVSLQIREIFSRYTQLVEPLSLDEAYLDVSECQQYKGSAT
HHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHCCCHHH
LIAQAIRRDILAETGLTASAGIAPVKFLAKVASDLNKPNGQYVITPETLPEFVKTLSLRK
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHC
IPGVGKVTAEKLSSLGLNTCGDVQAYSKPELLARFGKFGGVLIERSQGIDERGISADRER
CCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHH
KSVGVETTLAKDIYSLEQCQQVMPGLIQELALRLSRSAKERKIHKQVVKLKFNDFKQTTI
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHRSDEVSIVMFYDLLAQAMARQEGRGIRLLGISVGLADSILAVSEIPNAQTQLDLAL
HCCCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHCCCCHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA