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The map label for this gene is siaP [H]

Identifier: 126173166

GI number: 126173166

Start: 1058125

End: 1059327

Strand: Direct

Name: siaP [H]

Synonym: Sbal_0921

Alternate gene names: 126173166

Gene position: 1058125-1059327 (Clockwise)

Preceding gene: 126173165

Following gene: 126173167

Centisome position: 20.64

GC content: 49.63

Gene sequence:

>1203_bases
ATGCGACTGCGGAGCTCTGTCCTGAGAGCATGTTCACGTCTGTTAGAACCATGGGCTCGTTTGATGTCAGGGAGAGTATT
AAAAATGCGTAAGTTTGGGAGTGTACTCGTCTTAATGCTGCTGATGGGGCTGAGCGGTTGTAATCCCGCAGCCAGTGATG
CGCAAAGCGTAGTCGTTTCCAATGCCGCAACGGATGACCCCCAAGCTATTCCCGTTATTGAATGGCGCCTTGCGACCTCT
TGGCCCAAAAACTTCCCCGGTTTAGGTATGGCTCCAGAACGCTTTGCCCATTTAGTCAATGACATGTCTAACGGTCGGTT
AAAGATCCACGTTTATGGCGCGGGTGAGTTAATGCCAGCGTTTGCCGTATTTGATGGTGTGAGTCAGGGTAAAATTCAAA
TGGCCCATGCCGCTTCTTACTACTGGAAAGGCAAGGCTCCCGCGGCGCAGTTTTTTTCATCGATTCCCTTTGGTATGACG
GCGCAGGAAATGAACGGCTGGCTTCACTACGGCGGTGGCATGGCGTTGTGGGATGAAGTGTATCGCCCCTTTGGCATCAT
TCCCCTCGCGGGCGGCAATACTGGGATGCAAATGGGCGGCTGGTTCAATAAACCGATTAATACGATTGCTGATTTTAAGG
GGCTGAAGATCCGCATGCCGGGCTTGGGCGGCGAAGTATTAAAGCGTGTCGGTGCTATTCCTGTGAATATGGCGGGGCGT
GAACTCTATGGTGCATTGCAAACAGGCTCGATTGATGCGGCTGAGTGGGTAGGGCCATTGAACGACCTTGCTTTCGGTCT
ACATAAAGTGGCGAAGTACTACTATTACCCTGGTTGGCATGAGCCGGGTTCTAATATGGAATTCTTGATTAATAAAGCCG
CCTTCGAGAGTTTACCTCAAGATTTACAAGTCATAGTTAAAGTCGCGGCGAGAGCCATTAACCAAGATATGCTGGATGAA
TACACGACCCGTAATGTTGCCGCCCTTGAAACCTTAGTGAATGATGAAGGGGTGGTGCTTAAGGCGTTTCCACCGAAAGT
GTTGTTGGAACTTGAGAAAATCTCTAAACAAGTGATTGAAGAGCAAGCTAATCAAGATCCCTTAATGCGCAAAGTGTACG
CCGCCTATCACGCCTACGAGCAAGGTGTGCGCCAGTATCATAAAATATCTGAGGATGCTTACAGCCAACAGCGTCAACAC
TAA

Upstream 100 bases:

>100_bases
GGTCAAACTAAGGCCATTTTCTGGTTTCCTTGCCCGAGTTTCTGGTTTCCCTATAGGCGTTTCTGTGTTAACAATATGTT
CTATTTTAAGGGTTTGGGTG

Downstream 100 bases:

>100_bases
ATGCGTGCTGTTTTTAGCACTCACTGTCACATTAACAGCTGATTTATATGAGATGATTTCATCTTAAATTATCTTGTTAT
CGGCGTAATTCATTTGGTGT

Product: TRAP dicarboxylate transporter- DctP subunit

Products: NA

Alternate protein names: Extracytoplasmic solute receptor protein siaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MRLRSSVLRACSRLLEPWARLMSGRVLKMRKFGSVLVLMLLMGLSGCNPAASDAQSVVVSNAATDDPQAIPVIEWRLATS
WPKNFPGLGMAPERFAHLVNDMSNGRLKIHVYGAGELMPAFAVFDGVSQGKIQMAHAASYYWKGKAPAAQFFSSIPFGMT
AQEMNGWLHYGGGMALWDEVYRPFGIIPLAGGNTGMQMGGWFNKPINTIADFKGLKIRMPGLGGEVLKRVGAIPVNMAGR
ELYGALQTGSIDAAEWVGPLNDLAFGLHKVAKYYYYPGWHEPGSNMEFLINKAAFESLPQDLQVIVKVAARAINQDMLDE
YTTRNVAALETLVNDEGVVLKAFPPKVLLELEKISKQVIEEQANQDPLMRKVYAAYHAYEQGVRQYHKISEDAYSQQRQH

Sequences:

>Translated_400_residues
MRLRSSVLRACSRLLEPWARLMSGRVLKMRKFGSVLVLMLLMGLSGCNPAASDAQSVVVSNAATDDPQAIPVIEWRLATS
WPKNFPGLGMAPERFAHLVNDMSNGRLKIHVYGAGELMPAFAVFDGVSQGKIQMAHAASYYWKGKAPAAQFFSSIPFGMT
AQEMNGWLHYGGGMALWDEVYRPFGIIPLAGGNTGMQMGGWFNKPINTIADFKGLKIRMPGLGGEVLKRVGAIPVNMAGR
ELYGALQTGSIDAAEWVGPLNDLAFGLHKVAKYYYYPGWHEPGSNMEFLINKAAFESLPQDLQVIVKVAARAINQDMLDE
YTTRNVAALETLVNDEGVVLKAFPPKVLLELEKISKQVIEEQANQDPLMRKVYAAYHAYEQGVRQYHKISEDAYSQQRQH
>Mature_400_residues
MRLRSSVLRACSRLLEPWARLMSGRVLKMRKFGSVLVLMLLMGLSGCNPAASDAQSVVVSNAATDDPQAIPVIEWRLATS
WPKNFPGLGMAPERFAHLVNDMSNGRLKIHVYGAGELMPAFAVFDGVSQGKIQMAHAASYYWKGKAPAAQFFSSIPFGMT
AQEMNGWLHYGGGMALWDEVYRPFGIIPLAGGNTGMQMGGWFNKPINTIADFKGLKIRMPGLGGEVLKRVGAIPVNMAGR
ELYGALQTGSIDAAEWVGPLNDLAFGLHKVAKYYYYPGWHEPGSNMEFLINKAAFESLPQDLQVIVKVAARAINQDMLDE
YTTRNVAALETLVNDEGVVLKAFPPKVLLELEKISKQVIEEQANQDPLMRKVYAAYHAYEQGVRQYHKISEDAYSQQRQH

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [H]

COG id: COG4663

COG function: function code Q; TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 7 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018389
- InterPro:   IPR004682 [H]

Pfam domain/function: PF03480 SBP_bac_7 [H]

EC number: NA

Molecular weight: Translated: 44243; Mature: 44243

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLRSSVLRACSRLLEPWARLMSGRVLKMRKFGSVLVLMLLMGLSGCNPAASDAQSVVVS
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEE
NAATDDPQAIPVIEWRLATSWPKNFPGLGMAPERFAHLVNDMSNGRLKIHVYGAGELMPA
CCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCHHHHH
FAVFDGVSQGKIQMAHAASYYWKGKAPAAQFFSSIPFGMTAQEMNGWLHYGGGMALWDEV
HHHHCCCCCCCEEEHHHHHHEECCCCHHHHHHHCCCCCCCHHHHCCEEEECCCHHHHHHH
YRPFGIIPLAGGNTGMQMGGWFNKPINTIADFKGLKIRMPGLGGEVLKRVGAIPVNMAGR
CCCCCEEEECCCCCCCCCCCCCCCCHHHHHCCCCCEEECCCCCHHHHHHHCCCCCCCCCH
ELYGALQTGSIDAAEWVGPLNDLAFGLHKVAKYYYYPGWHEPGSNMEFLINKAAFESLPQ
HHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCHH
DLQVIVKVAARAINQDMLDEYTTRNVAALETLVNDEGVVLKAFPPKVLLELEKISKQVIE
HHHHHHHHHHHHHCHHHHHHHHHCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHH
EQANQDPLMRKVYAAYHAYEQGVRQYHKISEDAYSQQRQH
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLRSSVLRACSRLLEPWARLMSGRVLKMRKFGSVLVLMLLMGLSGCNPAASDAQSVVVS
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEE
NAATDDPQAIPVIEWRLATSWPKNFPGLGMAPERFAHLVNDMSNGRLKIHVYGAGELMPA
CCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCHHHHH
FAVFDGVSQGKIQMAHAASYYWKGKAPAAQFFSSIPFGMTAQEMNGWLHYGGGMALWDEV
HHHHCCCCCCCEEEHHHHHHEECCCCHHHHHHHCCCCCCCHHHHCCEEEECCCHHHHHHH
YRPFGIIPLAGGNTGMQMGGWFNKPINTIADFKGLKIRMPGLGGEVLKRVGAIPVNMAGR
CCCCCEEEECCCCCCCCCCCCCCCCHHHHHCCCCCEEECCCCCHHHHHHHCCCCCCCCCH
ELYGALQTGSIDAAEWVGPLNDLAFGLHKVAKYYYYPGWHEPGSNMEFLINKAAFESLPQ
HHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCHH
DLQVIVKVAARAINQDMLDEYTTRNVAALETLVNDEGVVLKAFPPKVLLELEKISKQVIE
HHHHHHHHHHHHHCHHHHHHHHHCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHH
EQANQDPLMRKVYAAYHAYEQGVRQYHKISEDAYSQQRQH
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA