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The map label for this gene is luxS

Identifier: 126173167

GI number: 126173167

Start: 1059496

End: 1060005

Strand: Direct

Name: luxS

Synonym: Sbal_0922

Alternate gene names: 126173167

Gene position: 1059496-1060005 (Clockwise)

Preceding gene: 126173166

Following gene: 126173168

Centisome position: 20.66

GC content: 44.51

Gene sequence:

>510_bases
ATGCCATTACTTGATAGCTTTACCGTCGATCATACTCGAATGAATGCCCCAGCAGTTCGTGTTGCTAAGCACATGAGCAC
GCCAAAGGGCGATGCGATTACGGTATTTGATCTACGTTTTTGCGCACCGAATAAAGATATTCTCAGTGAGCGTGGTATTC
ACACTCTGGAGCATTTATTCGCTGGCTTTATGCGTGACCATTTAAATGGTAGCAATGTTGAGATCATCGATATTTCGCCA
ATGGGATGTCGTACCGGCTTTTATATGAGTTTGATTGGTGAGCCGACTGAGCGCCAAGTGGCCGATGCGTGGTTAGCTGC
GATGGAAGATGTGCTTAAAGTGGTTGAGCAGTCTGAAATCCCTGAGCTGAACGAATACCAATGTGGTACGTATGAGATGC
ATTCATTAGAGCAGGCACAAGATATCGCCCGTAATATTATTGCGGCTGGCGTAAGTGTTAATCGCAATGATGATTTGAAA
TTAAGCGACGAAATTCTAGGTAATCTGTAA

Upstream 100 bases:

>100_bases
TTATCTTGTTATCGGCGTAATTCATTTGGTGTTATGCTTGCAAGCCATAAATAGACAGTTACAGTGGCGTTGATGTCGCC
CTGAGAATTTGGAGATCCCT

Downstream 100 bases:

>100_bases
CGGTTTGCACTCTTACTTGTATAAGAGTGCCTAGCCAGTAAATTCAGTTTCCTGAAGTTAATGAGAGAAAGCGACGAGAG
TCGCTTTTTTTTTCAAACAA

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MPLLDSFTVDHTRMNAPAVRVAKHMSTPKGDAITVFDLRFCAPNKDILSERGIHTLEHLFAGFMRDHLNGSNVEIIDISP
MGCRTGFYMSLIGEPTERQVADAWLAAMEDVLKVVEQSEIPELNEYQCGTYEMHSLEQAQDIARNIIAAGVSVNRNDDLK
LSDEILGNL

Sequences:

>Translated_169_residues
MPLLDSFTVDHTRMNAPAVRVAKHMSTPKGDAITVFDLRFCAPNKDILSERGIHTLEHLFAGFMRDHLNGSNVEIIDISP
MGCRTGFYMSLIGEPTERQVADAWLAAMEDVLKVVEQSEIPELNEYQCGTYEMHSLEQAQDIARNIIAAGVSVNRNDDLK
LSDEILGNL
>Mature_168_residues
PLLDSFTVDHTRMNAPAVRVAKHMSTPKGDAITVFDLRFCAPNKDILSERGIHTLEHLFAGFMRDHLNGSNVEIIDISPM
GCRTGFYMSLIGEPTERQVADAWLAAMEDVLKVVEQSEIPELNEYQCGTYEMHSLEQAQDIARNIIAAGVSVNRNDDLKL
SDEILGNL

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=169, Percent_Identity=75.7396449704142, Blast_Score=275, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_SHEB2 (B8EC51)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002359275.1
- ProteinModelPortal:   B8EC51
- SMR:   B8EC51
- GeneID:   7087194
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_3368
- HOGENOM:   HBG347473
- OMA:   VRIAKTM
- ProtClustDB:   PRK02260
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 18832; Mature: 18700

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDSFTVDHTRMNAPAVRVAKHMSTPKGDAITVFDLRFCAPNKDILSERGIHTLEHLF
CCCCCCCCCCCHHCCCHHHHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHCCHHHHHHHH
AGFMRDHLNGSNVEIIDISPMGCRTGFYMSLIGEPTERQVADAWLAAMEDVLKVVEQSEI
HHHHHHCCCCCCEEEEECCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PELNEYQCGTYEMHSLEQAQDIARNIIAAGVSVNRNDDLKLSDEILGNL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECHHHHCCC
>Mature Secondary Structure 
PLLDSFTVDHTRMNAPAVRVAKHMSTPKGDAITVFDLRFCAPNKDILSERGIHTLEHLF
CCCCCCCCCCHHCCCHHHHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHCCHHHHHHHH
AGFMRDHLNGSNVEIIDISPMGCRTGFYMSLIGEPTERQVADAWLAAMEDVLKVVEQSEI
HHHHHHCCCCCCEEEEECCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PELNEYQCGTYEMHSLEQAQDIARNIIAAGVSVNRNDDLKLSDEILGNL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA