Click here to switch to the map view.

The map label for this gene is tkt1 [H]

Identifier: 126173072

GI number: 126173072

Start: 929341

End: 931335

Strand: Direct

Name: tkt1 [H]

Synonym: Sbal_0827

Alternate gene names: 126173072

Gene position: 929341-931335 (Clockwise)

Preceding gene: 126173070

Following gene: 229220586

Centisome position: 18.13

GC content: 50.03

Gene sequence:

>1995_bases
ATGTCTTCCCGTAAAGTACTCGCAAACGCAATCCGTGCGTTAAGTATGGATGCAGTTCAAAAAGCAAATTCAGGCCATCC
CGGCGCCCCAATGGGTATGGCAGATATTGCTGAAGTGCTGTGGAATGATTTCCTTAAGCACAACCCGACCAATCCTAAAT
GGGTAGATAGAGACCGTTTCGTCCTTTCTAACGGTCACGGTTCAATGCTGATCTACTCTTTACTTCACCTGACAGGTTAT
GAATTACCAATCGAAGAACTGAAACAGTTCCGTCAATTGCATTCAAAAACCCCGGGTCACCCAGAATACGGTTACACCCC
AGGTGTTGAAACCACAACGGGTCCACTCGGCGCGGGCATCAGCAATGCTGTCGGTATGGCGATTGCTGAAAAAACCTTAG
CGGCACAGTTTAACCGTGATGGTCACGATATCGTTGATCACTACACTTACTGCTTCGTCGGCGACGGTTGTTTGATGGAA
GGTATTTCCCACGAAGCCTGTTCATTAGCCGGTACTTTAGGTCTAGGCAAACTGGTCGCATTTTGGGATGACAACGGTAT
TTCTATTGATGGCCATGTTGAAGGCTGGTTCACCGATGATACGCCAAAGCGTTTTGAAGCTTACGGCTGGCATGTGATTG
CCGGTGTTGACGGTCACGATAGCGCGGCAATCCGTGCTGCTATCGAAGCGGCGAAAGCGGTGACCGATAAACCAACCATG
ATTTGCTGCAAAACCATTATCGGTTTTGGCTCACCCAACAAATCTGGCAGCCACGATTGCCACGGCGCGCCATTAGGCGA
TGCGGAAATCGCCGCAGCCCGTGAATTCCTTGGCTGGCCATACGCCCCATTTGAAATCCCTGCTGACGTTTATGCCGGTT
GGGATGCCAAAGAAGCCGGTGCTGCCCGTGAAGCGGCATGGAACGAGAAGTTTGCTGCTTATAGCGCAGCTCACCCAGAA
CTGGCTGCTGAATACGAGCGCCGTGTACTGAAAGGTGAATTACCTGCTGATTTTGAAGAAAAAGCGCAGGCATTCGTGCA
AGCATCACAGGACAAAGCCGAAGGTATTGCGAGCCGTAAAGCCTCACAAAATGCCATCGGTGCTTTCGGTGCCATGTTAC
CTGAACTGTTAGGCGGCTCTGCTGACTTAGCGGGTTCTAACTTGACACTGTGGTCAGGTTCTAAAGGTATTCAAGACGAT
CCAGCTGGTAACTACATTTACTACGGCGTGCGTGAATTTGGCATGAGCGGCATTATGAACGGTGCTTCGCTGCATGGTGG
TTTCATCAACTACGGCGCAACTTTCATGATGTTCATGGAATACGCACGTAACGCAGTCCGCATGTCGGCGCTGATGGGCA
TTCAAAACATCTTCGTTTATACCCATGACTCTATCGGTCAAGGTGAAGATGGTCCAACGCATCAGCCAGTTGAGCAACTA
GCTAACCTGCGTATGACGCCAAATATGGCCGTATGGCGCCCATGTGATGCGGCAGAAACGGCGGTTTCTTGGAAAGCTGC
GATTCAACGTCGCAATGCGCCAACGTCACTGATTTTCAGCCGTCAAAACCTCAAAGCCCAAGCGCGTACCGCTGAGCAAT
TAGCCAACGTGGCTAAAGGTGCTTATGTACTGCAAGACTGTGCGGGTACACCAGAACTGATCCTGATCGCAACCGGTAGC
GAAGTACAATTGGCGATGGATTCTGCGGCTGCATTAACTGAGCAAGGTAAACAAGTTCGCGTAGTCTCTATGCCATCGAC
AACTGAGTTCGATAAGCAAGATGCCGCTTATAAAGAATCGGTATTACCACGCGCTGTGACTAAACGTGTGGCTATCGAAG
CGGCGCATACCGATTTCTGGTACAAGTACGTCGGTTTTGAAGGCACTGTTGTTGGCATGACCACTTTTGGTGAGTCAGCG
CCGGGTAACGTGTTATTGAATCACTTCGGTTTCACCGTTGAAAATGTGCTGAATGCTGCAAAATCATTGGGCTAA

Upstream 100 bases:

>100_bases
TGCTGAGTGAATGATAATTTTAGTTTGCGTCACACTGGCATGTAGGGGAAAATATGCATCCAAATTGCCCGCTAGACCCC
ACAAACAAGCAGGAGAGAGC

Downstream 100 bases:

>100_bases
TCGCTCAAGGGATTAGATTCAATACAAAAGGTTAAACTTTTTAAGTGTTAATCTGTATAATGCGGCCTGCAATCTTTTGC
AGGCCGTTTTTGTATTTAGA

Product: transketolase

Products: NA

Alternate protein names: TK 1 [H]

Number of amino acids: Translated: 664; Mature: 663

Protein sequence:

>664_residues
MSSRKVLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPTNPKWVDRDRFVLSNGHGSMLIYSLLHLTGY
ELPIEELKQFRQLHSKTPGHPEYGYTPGVETTTGPLGAGISNAVGMAIAEKTLAAQFNRDGHDIVDHYTYCFVGDGCLME
GISHEACSLAGTLGLGKLVAFWDDNGISIDGHVEGWFTDDTPKRFEAYGWHVIAGVDGHDSAAIRAAIEAAKAVTDKPTM
ICCKTIIGFGSPNKSGSHDCHGAPLGDAEIAAAREFLGWPYAPFEIPADVYAGWDAKEAGAAREAAWNEKFAAYSAAHPE
LAAEYERRVLKGELPADFEEKAQAFVQASQDKAEGIASRKASQNAIGAFGAMLPELLGGSADLAGSNLTLWSGSKGIQDD
PAGNYIYYGVREFGMSGIMNGASLHGGFINYGATFMMFMEYARNAVRMSALMGIQNIFVYTHDSIGQGEDGPTHQPVEQL
ANLRMTPNMAVWRPCDAAETAVSWKAAIQRRNAPTSLIFSRQNLKAQARTAEQLANVAKGAYVLQDCAGTPELILIATGS
EVQLAMDSAAALTEQGKQVRVVSMPSTTEFDKQDAAYKESVLPRAVTKRVAIEAAHTDFWYKYVGFEGTVVGMTTFGESA
PGNVLLNHFGFTVENVLNAAKSLG

Sequences:

>Translated_664_residues
MSSRKVLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPTNPKWVDRDRFVLSNGHGSMLIYSLLHLTGY
ELPIEELKQFRQLHSKTPGHPEYGYTPGVETTTGPLGAGISNAVGMAIAEKTLAAQFNRDGHDIVDHYTYCFVGDGCLME
GISHEACSLAGTLGLGKLVAFWDDNGISIDGHVEGWFTDDTPKRFEAYGWHVIAGVDGHDSAAIRAAIEAAKAVTDKPTM
ICCKTIIGFGSPNKSGSHDCHGAPLGDAEIAAAREFLGWPYAPFEIPADVYAGWDAKEAGAAREAAWNEKFAAYSAAHPE
LAAEYERRVLKGELPADFEEKAQAFVQASQDKAEGIASRKASQNAIGAFGAMLPELLGGSADLAGSNLTLWSGSKGIQDD
PAGNYIYYGVREFGMSGIMNGASLHGGFINYGATFMMFMEYARNAVRMSALMGIQNIFVYTHDSIGQGEDGPTHQPVEQL
ANLRMTPNMAVWRPCDAAETAVSWKAAIQRRNAPTSLIFSRQNLKAQARTAEQLANVAKGAYVLQDCAGTPELILIATGS
EVQLAMDSAAALTEQGKQVRVVSMPSTTEFDKQDAAYKESVLPRAVTKRVAIEAAHTDFWYKYVGFEGTVVGMTTFGESA
PGNVLLNHFGFTVENVLNAAKSLG
>Mature_663_residues
SSRKVLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPTNPKWVDRDRFVLSNGHGSMLIYSLLHLTGYE
LPIEELKQFRQLHSKTPGHPEYGYTPGVETTTGPLGAGISNAVGMAIAEKTLAAQFNRDGHDIVDHYTYCFVGDGCLMEG
ISHEACSLAGTLGLGKLVAFWDDNGISIDGHVEGWFTDDTPKRFEAYGWHVIAGVDGHDSAAIRAAIEAAKAVTDKPTMI
CCKTIIGFGSPNKSGSHDCHGAPLGDAEIAAAREFLGWPYAPFEIPADVYAGWDAKEAGAAREAAWNEKFAAYSAAHPEL
AAEYERRVLKGELPADFEEKAQAFVQASQDKAEGIASRKASQNAIGAFGAMLPELLGGSADLAGSNLTLWSGSKGIQDDP
AGNYIYYGVREFGMSGIMNGASLHGGFINYGATFMMFMEYARNAVRMSALMGIQNIFVYTHDSIGQGEDGPTHQPVEQLA
NLRMTPNMAVWRPCDAAETAVSWKAAIQRRNAPTSLIFSRQNLKAQARTAEQLANVAKGAYVLQDCAGTPELILIATGSE
VQLAMDSAAALTEQGKQVRVVSMPSTTEFDKQDAAYKESVLPRAVTKRVAIEAAHTDFWYKYVGFEGTVVGMTTFGESAP
GNVLLNHFGFTVENVLNAAKSLG

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=603, Percent_Identity=25.8706467661692, Blast_Score=146, Evalue=7e-35,
Organism=Homo sapiens, GI4507521, Length=603, Percent_Identity=25.8706467661692, Blast_Score=146, Evalue=7e-35,
Organism=Homo sapiens, GI133778974, Length=259, Percent_Identity=33.5907335907336, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI225637459, Length=260, Percent_Identity=26.1538461538462, Blast_Score=77, Evalue=8e-14,
Organism=Escherichia coli, GI48994911, Length=663, Percent_Identity=74.6606334841629, Blast_Score=1059, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=663, Percent_Identity=66.6666666666667, Blast_Score=954, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=677, Percent_Identity=24.6676514032496, Blast_Score=152, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6325331, Length=668, Percent_Identity=47.7544910179641, Blast_Score=578, Evalue=1e-165,
Organism=Saccharomyces cerevisiae, GI6319593, Length=669, Percent_Identity=45.2914798206278, Blast_Score=539, Evalue=1e-154,
Organism=Drosophila melanogaster, GI45551847, Length=685, Percent_Identity=25.4014598540146, Blast_Score=165, Evalue=8e-41,
Organism=Drosophila melanogaster, GI45550715, Length=685, Percent_Identity=25.4014598540146, Blast_Score=165, Evalue=8e-41,
Organism=Drosophila melanogaster, GI24666278, Length=683, Percent_Identity=24.3045387994143, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24645119, Length=651, Percent_Identity=24.7311827956989, Blast_Score=142, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 71350; Mature: 71219

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRKVLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPTNPKWVDRDRF
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCE
VLSNGHGSMLIYSLLHLTGYELPIEELKQFRQLHSKTPGHPEYGYTPGVETTTGPLGAGI
EEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCH
SNAVGMAIAEKTLAAQFNRDGHDIVDHYTYCFVGDGCLMEGISHEACSLAGTLGLGKLVA
HHHHHHHHHHHHHHHHHCCCCHHHHHCCEEEEECCCHHHHCCCHHHHHHHHHCCCCCEEE
FWDDNGISIDGHVEGWFTDDTPKRFEAYGWHVIAGVDGHDSAAIRAAIEAAKAVTDKPTM
EECCCCEEECCCEEEEECCCCCHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHH
ICCKTIIGFGSPNKSGSHDCHGAPLGDAEIAAAREFLGWPYAPFEIPADVYAGWDAKEAG
HHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCCCHHCC
AAREAAWNEKFAAYSAAHPELAAEYERRVLKGELPADFEEKAQAFVQASQDKAEGIASRK
CHHHHHHCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ASQNAIGAFGAMLPELLGGSADLAGSNLTLWSGSKGIQDDPAGNYIYYGVREFGMSGIMN
CCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCEEEECHHHHCHHHCCC
GASLHGGFINYGATFMMFMEYARNAVRMSALMGIQNIFVYTHDSIGQGEDGPTHQPVEQL
CCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCHHHHHHH
ANLRMTPNMAVWRPCDAAETAVSWKAAIQRRNAPTSLIFSRQNLKAQARTAEQLANVAKG
HCCCCCCCCCEECCCCHHHHHHHHHHHHHHCCCCHHEEEECCCHHHHHHHHHHHHHHHHH
AYVLQDCAGTPELILIATGSEVQLAMDSAAALTEQGKQVRVVSMPSTTEFDKQDAAYKES
HHHHHHCCCCCCEEEEECCCCEEEEHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHH
VLPRAVTKRVAIEAAHTDFWYKYVGFEGTVVGMTTFGESAPGNVLLNHFGFTVENVLNAA
HHHHHHHHHHHHEECCCCCEEEEECCCCEEEEEEECCCCCCCCEEHHHHCCHHHHHHHHH
KSLG
HHCC
>Mature Secondary Structure 
SSRKVLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPTNPKWVDRDRF
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCE
VLSNGHGSMLIYSLLHLTGYELPIEELKQFRQLHSKTPGHPEYGYTPGVETTTGPLGAGI
EEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCH
SNAVGMAIAEKTLAAQFNRDGHDIVDHYTYCFVGDGCLMEGISHEACSLAGTLGLGKLVA
HHHHHHHHHHHHHHHHHCCCCHHHHHCCEEEEECCCHHHHCCCHHHHHHHHHCCCCCEEE
FWDDNGISIDGHVEGWFTDDTPKRFEAYGWHVIAGVDGHDSAAIRAAIEAAKAVTDKPTM
EECCCCEEECCCEEEEECCCCCHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHH
ICCKTIIGFGSPNKSGSHDCHGAPLGDAEIAAAREFLGWPYAPFEIPADVYAGWDAKEAG
HHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCCCHHCC
AAREAAWNEKFAAYSAAHPELAAEYERRVLKGELPADFEEKAQAFVQASQDKAEGIASRK
CHHHHHHCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ASQNAIGAFGAMLPELLGGSADLAGSNLTLWSGSKGIQDDPAGNYIYYGVREFGMSGIMN
CCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCEEEECHHHHCHHHCCC
GASLHGGFINYGATFMMFMEYARNAVRMSALMGIQNIFVYTHDSIGQGEDGPTHQPVEQL
CCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCHHHHHHH
ANLRMTPNMAVWRPCDAAETAVSWKAAIQRRNAPTSLIFSRQNLKAQARTAEQLANVAKG
HCCCCCCCCCEECCCCHHHHHHHHHHHHHHCCCCHHEEEECCCHHHHHHHHHHHHHHHHH
AYVLQDCAGTPELILIATGSEVQLAMDSAAALTEQGKQVRVVSMPSTTEFDKQDAAYKES
HHHHHHCCCCCCEEEEECCCCEEEEHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHH
VLPRAVTKRVAIEAAHTDFWYKYVGFEGTVVGMTTFGESAPGNVLLNHFGFTVENVLNAA
HHHHHHHHHHHHEECCCCCEEEEECCCCEEEEEEECCCCCCCCEEHHHHCCHHHHHHHHH
KSLG
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]