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The map label for this gene is epd [H]

Identifier: 229220586

GI number: 229220586

Start: 931452

End: 932468

Strand: Direct

Name: epd [H]

Synonym: Sbal_0828

Alternate gene names: 229220586

Gene position: 931452-932468 (Clockwise)

Preceding gene: 126173072

Following gene: 126173074

Centisome position: 18.17

GC content: 49.85

Gene sequence:

>1017_bases
ATGATCCGAGTCGCTATCAATGGTTATGGCCGTATCGGCCGCTCTATTCTTCGTGCTTTGTACGAGTCTGGAAAACGGCA
GCAAATACAGATTGTCGCGATTAATGAATTAGCTAAACCTGAAGCCATTATTCATCTGACCCAGTACGACACCACCCACG
GTCGGTTTGCGCACAAAGTGAAACTCGTCGATGATCACATGCTGATTGGCGACGATGCGATAAAAATTCTCCACGAGCCC
GATCCCACAAAACTCCCTTGGCATGAAATGGACATAGACATTGTCTATGAGGCCACAGGTGTATTACTCGATCGTCAAAG
CTGCGAAGCCCATATTCATGCTGGCGCTAAGCAAGTGCTGATAAGCCATCCATCCTCAGCCGATGTCGATGGCACGATTG
TCTATGGTGTGAATCACGATTTACTCCGCGCCGAACACACAGTGGTTTCCAACGCATCTTGTACGACTAACTGTATCGTG
CCTGTGATCGACGTACTCGATCGCCATTTCGGCGTTAAAAGCGGTGCCATTACCACTATTCATTCGGCGATGAACGATCA
GCAAGTGATTGATGCTTATCATGATGACTTACGTCGTACCCGCGCCGCTGGTCAATCGATTATCCCTGTAGACACTAAGC
TTGCCCGCGGCATTGAGCGGATTTTGCCGCACATGAAAGATAAGTTTGAAGCGATTTCGGTGCGCGTGCCCACCATCAAC
GTGACCGCAATCGATTTGTCTGTGACGCTGGAGAAAACCGTCGATATTGCCACTGTGAATCATGTGCTGGAGTCGGCCGC
CAATGGGCGATTTAACGGCATTTTGGGTTATACTGATGAGCCCTTGGTTTCATGTGATTTCAACCATGATCCGCGCTCCA
GTATTGTTGACGGTACCCAGACCCGTGTCAGCGCCGGTCAACTGGTGAAGCTGTTGTTGTGGTGCGATAACGAGTGGGGT
TTTGCCAATCGTATGTTAGATACGAGTTTGGCGATGATCGCAGCCAAGCGAGGCTGA

Upstream 100 bases:

>100_bases
ATTCAATACAAAAGGTTAAACTTTTTAAGTGTTAATCTGTATAATGCGGCCTGCAATCTTTTGCAGGCCGTTTTTGTATT
TAGAGGAAATTGAGACCTCA

Downstream 100 bases:

>100_bases
TAAAAAGTAGATTATTCACCGGTGGGTCACTCAGTTATATGCCAATTCGACGGGATGTCGAGCGCCTAGCGGCAGTAAAC
TGATACCGGCCATGTGTGAA

Product: erythrose 4-phosphate dehydrogenase

Products: NA

Alternate protein names: E4PDH [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MIRVAINGYGRIGRSILRALYESGKRQQIQIVAINELAKPEAIIHLTQYDTTHGRFAHKVKLVDDHMLIGDDAIKILHEP
DPTKLPWHEMDIDIVYEATGVLLDRQSCEAHIHAGAKQVLISHPSSADVDGTIVYGVNHDLLRAEHTVVSNASCTTNCIV
PVIDVLDRHFGVKSGAITTIHSAMNDQQVIDAYHDDLRRTRAAGQSIIPVDTKLARGIERILPHMKDKFEAISVRVPTIN
VTAIDLSVTLEKTVDIATVNHVLESAANGRFNGILGYTDEPLVSCDFNHDPRSSIVDGTQTRVSAGQLVKLLLWCDNEWG
FANRMLDTSLAMIAAKRG

Sequences:

>Translated_338_residues
MIRVAINGYGRIGRSILRALYESGKRQQIQIVAINELAKPEAIIHLTQYDTTHGRFAHKVKLVDDHMLIGDDAIKILHEP
DPTKLPWHEMDIDIVYEATGVLLDRQSCEAHIHAGAKQVLISHPSSADVDGTIVYGVNHDLLRAEHTVVSNASCTTNCIV
PVIDVLDRHFGVKSGAITTIHSAMNDQQVIDAYHDDLRRTRAAGQSIIPVDTKLARGIERILPHMKDKFEAISVRVPTIN
VTAIDLSVTLEKTVDIATVNHVLESAANGRFNGILGYTDEPLVSCDFNHDPRSSIVDGTQTRVSAGQLVKLLLWCDNEWG
FANRMLDTSLAMIAAKRG
>Mature_338_residues
MIRVAINGYGRIGRSILRALYESGKRQQIQIVAINELAKPEAIIHLTQYDTTHGRFAHKVKLVDDHMLIGDDAIKILHEP
DPTKLPWHEMDIDIVYEATGVLLDRQSCEAHIHAGAKQVLISHPSSADVDGTIVYGVNHDLLRAEHTVVSNASCTTNCIV
PVIDVLDRHFGVKSGAITTIHSAMNDQQVIDAYHDDLRRTRAAGQSIIPVDTKLARGIERILPHMKDKFEAISVRVPTIN
VTAIDLSVTLEKTVDIATVNHVLESAANGRFNGILGYTDEPLVSCDFNHDPRSSIVDGTQTRVSAGQLVKLLLWCDNEWG
FANRMLDTSLAMIAAKRG

Specific function: Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate [H]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=338, Percent_Identity=38.7573964497041, Blast_Score=248, Evalue=6e-66,
Organism=Homo sapiens, GI7657116, Length=329, Percent_Identity=36.4741641337386, Blast_Score=229, Evalue=2e-60,
Organism=Escherichia coli, GI1789295, Length=331, Percent_Identity=66.1631419939577, Blast_Score=464, Evalue=1e-132,
Organism=Escherichia coli, GI1788079, Length=327, Percent_Identity=40.3669724770642, Blast_Score=264, Evalue=7e-72,
Organism=Caenorhabditis elegans, GI17534677, Length=333, Percent_Identity=39.3393393393393, Blast_Score=249, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI17534679, Length=333, Percent_Identity=39.039039039039, Blast_Score=247, Evalue=6e-66,
Organism=Caenorhabditis elegans, GI32566163, Length=341, Percent_Identity=38.41642228739, Blast_Score=239, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17568413, Length=341, Percent_Identity=38.41642228739, Blast_Score=239, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6322468, Length=329, Percent_Identity=38.6018237082067, Blast_Score=258, Evalue=7e-70,
Organism=Saccharomyces cerevisiae, GI6322409, Length=329, Percent_Identity=38.9057750759878, Blast_Score=256, Evalue=4e-69,
Organism=Saccharomyces cerevisiae, GI6321631, Length=329, Percent_Identity=38.2978723404255, Blast_Score=254, Evalue=1e-68,
Organism=Drosophila melanogaster, GI17933600, Length=329, Percent_Identity=37.3860182370821, Blast_Score=234, Evalue=6e-62,
Organism=Drosophila melanogaster, GI18110149, Length=329, Percent_Identity=37.3860182370821, Blast_Score=234, Evalue=6e-62,
Organism=Drosophila melanogaster, GI85725000, Length=329, Percent_Identity=37.3860182370821, Blast_Score=230, Evalue=9e-61,
Organism=Drosophila melanogaster, GI22023983, Length=329, Percent_Identity=37.3860182370821, Blast_Score=230, Evalue=9e-61,
Organism=Drosophila melanogaster, GI19922412, Length=332, Percent_Identity=34.3373493975904, Blast_Score=219, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006422
- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.72 [H]

Molecular weight: Translated: 37264; Mature: 37264

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVAINGYGRIGRSILRALYESGKRQQIQIVAINELAKPEAIIHLTQYDTTHGRFAHKV
CEEEEEECCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCEEEEE
KLVDDHMLIGDDAIKILHEPDPTKLPWHEMDIDIVYEATGVLLDRQSCEAHIHAGAKQVL
EEECCEEEECCCCEEEEECCCCCCCCCCCCCEEEEEEECCEEEECCCCHHHHHCCCEEEE
ISHPSSADVDGTIVYGVNHDLLRAEHTVVSNASCTTNCIVPVIDVLDRHFGVKSGAITTI
EECCCCCCCCEEEEEECCCHHHHHHHHEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHH
HSAMNDQQVIDAYHDDLRRTRAAGQSIIPVDTKLARGIERILPHMKDKFEAISVRVPTIN
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECEEE
VTAIDLSVTLEKTVDIATVNHVLESAANGRFNGILGYTDEPLVSCDFNHDPRSSIVDGTQ
EEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEECCCCCCCHHHCCCCH
TRVSAGQLVKLLLWCDNEWGFANRMLDTSLAMIAAKRG
HHCCHHHHEEEEEEECCCCCHHHHHHHHHHHHHEECCC
>Mature Secondary Structure
MIRVAINGYGRIGRSILRALYESGKRQQIQIVAINELAKPEAIIHLTQYDTTHGRFAHKV
CEEEEEECCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCEEEEE
KLVDDHMLIGDDAIKILHEPDPTKLPWHEMDIDIVYEATGVLLDRQSCEAHIHAGAKQVL
EEECCEEEECCCCEEEEECCCCCCCCCCCCCEEEEEEECCEEEECCCCHHHHHCCCEEEE
ISHPSSADVDGTIVYGVNHDLLRAEHTVVSNASCTTNCIVPVIDVLDRHFGVKSGAITTI
EECCCCCCCCEEEEEECCCHHHHHHHHEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHH
HSAMNDQQVIDAYHDDLRRTRAAGQSIIPVDTKLARGIERILPHMKDKFEAISVRVPTIN
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECEEE
VTAIDLSVTLEKTVDIATVNHVLESAANGRFNGILGYTDEPLVSCDFNHDPRSSIVDGTQ
EEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEECCCCCCCHHHCCCCH
TRVSAGQLVKLLLWCDNEWGFANRMLDTSLAMIAAKRG
HHCCHHHHEEEEEEECCCCCHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA