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The map label for this gene is nqrA [H]

Identifier: 126173000

GI number: 126173000

Start: 849616

End: 850989

Strand: Direct

Name: nqrA [H]

Synonym: Sbal_0754

Alternate gene names: 126173000

Gene position: 849616-850989 (Clockwise)

Preceding gene: 126172996

Following gene: 126173001

Centisome position: 16.57

GC content: 51.24

Gene sequence:

>1374_bases
ATGGCAGATTTTTCAAACCAAATTGTAACGATCAAAAAAGGCCTCGACTTGCCGATTGCTGGCGAGCCGCGACAGGTCAT
TGAACTCGGTGCTAAGCCATCCCAAGTGGCTGTTCTGGGTGAAGAATTCGTTGGGCTTAAGCCGACGATGTTGGTCGAAG
AGGGCGATTGGGTTCAAAAGGGCCAAGCCCTGTTTGAAGACAAAAAAACACCGGGCGTGTTATTCACTGCACCCGCTAGT
GGCCAAGTCGTGGCGATTAACCGCGGCGAGCGCCGAATTCTACAATCGGTTGTCATTCGTTGTGATGACGGCGAAAACCG
CGATGGACAGATTTCCTTCGAAATCCATCAAGACATCGCCGCTTTAGCAAGGTCAACCGTTCAGGCGCAATTAGTGAAAA
GCGGTCTATGGACTGCACTGCGTACGCGGCCTTTCTCGCGCGTGCCTGCGCTCGATAGCACGCCCGCAGGGATTTTTGTT
ACCGCAATTGATACTAATCCACTGGCCGCCGATCCGCGTTTAATCATCGCCGAGCAAACCGAAGCTTTTAAAGCTGGCTT
GCTGGTGTTGAGCCGCTTAACCGAAGGTAAGGTTTACCTGTGTCAGGATAAGGGCGAAGCGATTGTGAAAGAAGCATTAC
CACAACTTGAGGTGCGCCGATTTGACGGTGTTCATCCAGCTGGTTTAGTCGGCACTCATATTCACTTTACTTTACCTGTG
AGTTTAGAGCGTCAGGTATGGCATATCGGCTATCAAGACGTGATTGCCTACGGCAAGTTATTCCAAACCGGTGAGTTATA
TACCGACCGCATCGTCGCCTTAGGTGGCCCGAGCGTGCTAAATCCGCGTTTACTGCGCACTCAGTTGGGCGCCGAGTTAA
GTCCCTTAGTCAGTGATGACATCAAACCCGGCCAAAACCGCGTGGTATCGGGCTCTGTGTTATCTGGCCATACGGCGGTT
GGTGTGCATGACTTTTTAGGTAGATTCCACAACCAAGTGTCAGTGCTGAGCGAAGATGCGCAGCACCATGTACTTTCTTG
GGTACGGGGTGGCTCGGATAAATTCTCTATTACCCGCGCAGTGACATCACGTTTGTTTGGTGCCACTAAGCTGTTCGAAT
TCACTACCCATCAGGGCGGTTCAGCCCGCGCCATGATGGCCTTTGGTCAGCTAGATCGCGTGATGCCACTGGATATTTTA
CCCACCTTGCTCGTTCGAGACTTAGTGGTGCGTGATACCGATGAGGCGCAGGCCTTAGGTGCATTGGAGTTAGATGAAGA
AGATCTGGCGCTGTGTACTTTTGTGTGTCCCGGCAAATATGACTTTGGTAAAGAATTACGTGCCTGTCTAGATGTTATCG
AGAGGGAAGGTTAA

Upstream 100 bases:

>100_bases
CTTACGAATTTGCGGCGGAATGTGACGCCAATATCGGAAACTGGGTTAACAAATCTCTACCCTGAATTTATCTAAAAATT
TTTCATGGTTGATATTTGTG

Downstream 100 bases:

>100_bases
TGACTAAGCAAGTTAAAAAACCTGATTTACAGCAAGCCGCAGATTTACAAGAAGCTACTGATTTACAGGAAGAATACTAC
GCAACGGGTAAGTCGATGAA

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A [H]

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MADFSNQIVTIKKGLDLPIAGEPRQVIELGAKPSQVAVLGEEFVGLKPTMLVEEGDWVQKGQALFEDKKTPGVLFTAPAS
GQVVAINRGERRILQSVVIRCDDGENRDGQISFEIHQDIAALARSTVQAQLVKSGLWTALRTRPFSRVPALDSTPAGIFV
TAIDTNPLAADPRLIIAEQTEAFKAGLLVLSRLTEGKVYLCQDKGEAIVKEALPQLEVRRFDGVHPAGLVGTHIHFTLPV
SLERQVWHIGYQDVIAYGKLFQTGELYTDRIVALGGPSVLNPRLLRTQLGAELSPLVSDDIKPGQNRVVSGSVLSGHTAV
GVHDFLGRFHNQVSVLSEDAQHHVLSWVRGGSDKFSITRAVTSRLFGATKLFEFTTHQGGSARAMMAFGQLDRVMPLDIL
PTLLVRDLVVRDTDEAQALGALELDEEDLALCTFVCPGKYDFGKELRACLDVIEREG

Sequences:

>Translated_457_residues
MADFSNQIVTIKKGLDLPIAGEPRQVIELGAKPSQVAVLGEEFVGLKPTMLVEEGDWVQKGQALFEDKKTPGVLFTAPAS
GQVVAINRGERRILQSVVIRCDDGENRDGQISFEIHQDIAALARSTVQAQLVKSGLWTALRTRPFSRVPALDSTPAGIFV
TAIDTNPLAADPRLIIAEQTEAFKAGLLVLSRLTEGKVYLCQDKGEAIVKEALPQLEVRRFDGVHPAGLVGTHIHFTLPV
SLERQVWHIGYQDVIAYGKLFQTGELYTDRIVALGGPSVLNPRLLRTQLGAELSPLVSDDIKPGQNRVVSGSVLSGHTAV
GVHDFLGRFHNQVSVLSEDAQHHVLSWVRGGSDKFSITRAVTSRLFGATKLFEFTTHQGGSARAMMAFGQLDRVMPLDIL
PTLLVRDLVVRDTDEAQALGALELDEEDLALCTFVCPGKYDFGKELRACLDVIEREG
>Mature_456_residues
ADFSNQIVTIKKGLDLPIAGEPRQVIELGAKPSQVAVLGEEFVGLKPTMLVEEGDWVQKGQALFEDKKTPGVLFTAPASG
QVVAINRGERRILQSVVIRCDDGENRDGQISFEIHQDIAALARSTVQAQLVKSGLWTALRTRPFSRVPALDSTPAGIFVT
AIDTNPLAADPRLIIAEQTEAFKAGLLVLSRLTEGKVYLCQDKGEAIVKEALPQLEVRRFDGVHPAGLVGTHIHFTLPVS
LERQVWHIGYQDVIAYGKLFQTGELYTDRIVALGGPSVLNPRLLRTQLGAELSPLVSDDIKPGQNRVVSGSVLSGHTAVG
VHDFLGRFHNQVSVLSEDAQHHVLSWVRGGSDKFSITRAVTSRLFGATKLFEFTTHQGGSARAMMAFGQLDRVMPLDILP
TLLVRDLVVRDTDEAQALGALELDEEDLALCTFVCPGKYDFGKELRACLDVIEREG

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008703
- InterPro:   IPR022615 [H]

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB [H]

EC number: NA

Molecular weight: Translated: 49811; Mature: 49680

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFSNQIVTIKKGLDLPIAGEPRQVIELGAKPSQVAVLGEEFVGLKPTMLVEEGDWVQK
CCCCCCCEEEEECCCCCCCCCCCHHHHHCCCCCCEEEEECHHHCCCCCEEEEECCCHHHH
GQALFEDKKTPGVLFTAPASGQVVAINRGERRILQSVVIRCDDGENRDGQISFEIHQDIA
CHHHHHCCCCCCEEEECCCCCEEEEEECCHHHHHHHHEEECCCCCCCCCEEEEEEHHHHH
ALARSTVQAQLVKSGLWTALRTRPFSRVPALDSTPAGIFVTAIDTNPLAADPRLIIAEQT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCH
EAFKAGLLVLSRLTEGKVYLCQDKGEAIVKEALPQLEVRRFDGVHPAGLVGTHIHFTLPV
HHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHCCHHHHHHHCCCCCCCEEECEEEEEEEC
SLERQVWHIGYQDVIAYGKLFQTGELYTDRIVALGGPSVLNPRLLRTQLGAELSPLVSDD
EECCCEECCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCHHCCC
IKPGQNRVVSGSVLSGHTAVGVHDFLGRFHNQVSVLSEDAQHHVLSWVRGGSDKFSITRA
CCCCCCEEEECCEECCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
VTSRLFGATKLFEFTTHQGGSARAMMAFGQLDRVMPLDILPTLLVRDLVVRDTDEAQALG
HHHHHHHHHHHEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHCC
ALELDEEDLALCTFVCPGKYDFGKELRACLDVIEREG
CEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADFSNQIVTIKKGLDLPIAGEPRQVIELGAKPSQVAVLGEEFVGLKPTMLVEEGDWVQK
CCCCCCEEEEECCCCCCCCCCCHHHHHCCCCCCEEEEECHHHCCCCCEEEEECCCHHHH
GQALFEDKKTPGVLFTAPASGQVVAINRGERRILQSVVIRCDDGENRDGQISFEIHQDIA
CHHHHHCCCCCCEEEECCCCCEEEEEECCHHHHHHHHEEECCCCCCCCCEEEEEEHHHHH
ALARSTVQAQLVKSGLWTALRTRPFSRVPALDSTPAGIFVTAIDTNPLAADPRLIIAEQT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCH
EAFKAGLLVLSRLTEGKVYLCQDKGEAIVKEALPQLEVRRFDGVHPAGLVGTHIHFTLPV
HHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHCCHHHHHHHCCCCCCCEEECEEEEEEEC
SLERQVWHIGYQDVIAYGKLFQTGELYTDRIVALGGPSVLNPRLLRTQLGAELSPLVSDD
EECCCEECCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCHHCCC
IKPGQNRVVSGSVLSGHTAVGVHDFLGRFHNQVSVLSEDAQHHVLSWVRGGSDKFSITRA
CCCCCCEEEECCEECCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
VTSRLFGATKLFEFTTHQGGSARAMMAFGQLDRVMPLDILPTLLVRDLVVRDTDEAQALG
HHHHHHHHHHHEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHCC
ALELDEEDLALCTFVCPGKYDFGKELRACLDVIEREG
CEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA