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The map label for this gene is rstB [H]

Identifier: 126172996

GI number: 126172996

Start: 845036

End: 846328

Strand: Direct

Name: rstB [H]

Synonym: Sbal_0750

Alternate gene names: 126172996

Gene position: 845036-846328 (Clockwise)

Preceding gene: 126172995

Following gene: 126173000

Centisome position: 16.48

GC content: 48.18

Gene sequence:

>1293_bases
ATGAAGAAGTTGATGACTTCACTGGTGCTGGTGGTGCTGGTGGCCATTGCGAGCCTAGGCTGGTCGATAAGCGAGTTTGC
CAGTCTGCTAGATCATGATAATGACACGCAAACCCCAGCCACTCACCTCGCCGCATTAAAACTACTGGGCGGCACACTGG
CGCAAACGCTCGATAACGATAGCGTTAACAATCAAAGTATTATCGCAAACTGGAACCAGCTAAATTCAGAGCAATTGTCT
TTAGCGAGTGAAGCCGATTTCGTCTTACCCTCAGCCCTAAAAACCGCGTTTTATGCCGGGGAATCACTCCTGTTGGAGTC
CGATGACGGCATCTCCTTGCATTATTTACTGCCAAAAACGGGGCAGGTTTTAAACATCAATACCGATATTGTCACGCCCA
CCGATGTCAGCTTTGACTTGAATAAGCTGTATACCATGCTTTTTTATGGCGGCGTGGTGCTGATTTTGTTGGTGTGGGTG
TCACCCTTGATCCGTCAACTGGTTAATCTCAGTAAGGCGACCCAAGCGTTTGGTATGGGGGAGTTGCAGCAGAGAATTCC
TGTTAGAAAAACGTCGTACATAGGTACTATTGAAAGCGAATTCAACCGCATGGCGGATCGTATTCAGCAATTGATCGATG
ACAATAAACTGCTCAGTCGAGCAGTTTCTCACGATTTAAAAACCCCGATTGCACGGCTAAGATTTGGCATTGAGGCGCTG
GAAGAAACCCAAAGCGAACAGCTCAGAGTGAAGTATTTCCAGCGCTTGAACCGCGATCTAGACACTATGGAAGACTTGGT
GATGACGCTGCTGAGTTATGCCCGCCTCGATGAAGCGAATATCCAGCCCGATTGGCAGTCGATTGAGCTCAATGCTTGGC
TACTCGAAAAGTATCAAGGCCAAGTGTACCCCGATTTTTCAGTTGAACTGGTTTCCTATCCCACAGCACTCAAGATCAAG
ACAGATCCCAAGTACTTATCAATGCAGGTGAATAATTTGCTCAATAATGCGCTGCGTTTTGGTAAGGCAAAGATTCGGCT
GACGTTGGCAGTCGAGGAGGGCGCGACCTGGTTACACGTTGACGATGACGGTCCAGGCATAGATGAACTGGAGTCTATGC
AGGTGATTAAGCCTTTTGTGCGTGGTCAGCACAGTCGTGGAAATTCCGGTCATGGCATGGGATTGGCGATTGTCGACAGA
ATCGGTTATTGGATGAATGCCCCATTACGTATTGGACGTGCTCCTGAGCTCGGTGGCGCTCGCATGTCACTAAAATTCAA
GGCTGAAATTTAA

Upstream 100 bases:

>100_bases
TACGCAAGAAATTGCAGGAAGCGTTAAGCCAGCCCTATAAAGTGAAAACCATCCGTGGCAAGGGATACCTTTTTTGCCGT
GACGAGGGTGAGCAAGCTTT

Downstream 100 bases:

>100_bases
CGCTGAAGTTTCGGACTGGAGATTTAGACCGGAATTTAAGGCTGAATTTTAAAGCGGAGTTTAAGGCAAGAGTTTAAGAC
TGGATTTTAACGCTGCATAA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MKKLMTSLVLVVLVAIASLGWSISEFASLLDHDNDTQTPATHLAALKLLGGTLAQTLDNDSVNNQSIIANWNQLNSEQLS
LASEADFVLPSALKTAFYAGESLLLESDDGISLHYLLPKTGQVLNINTDIVTPTDVSFDLNKLYTMLFYGGVVLILLVWV
SPLIRQLVNLSKATQAFGMGELQQRIPVRKTSYIGTIESEFNRMADRIQQLIDDNKLLSRAVSHDLKTPIARLRFGIEAL
EETQSEQLRVKYFQRLNRDLDTMEDLVMTLLSYARLDEANIQPDWQSIELNAWLLEKYQGQVYPDFSVELVSYPTALKIK
TDPKYLSMQVNNLLNNALRFGKAKIRLTLAVEEGATWLHVDDDGPGIDELESMQVIKPFVRGQHSRGNSGHGMGLAIVDR
IGYWMNAPLRIGRAPELGGARMSLKFKAEI

Sequences:

>Translated_430_residues
MKKLMTSLVLVVLVAIASLGWSISEFASLLDHDNDTQTPATHLAALKLLGGTLAQTLDNDSVNNQSIIANWNQLNSEQLS
LASEADFVLPSALKTAFYAGESLLLESDDGISLHYLLPKTGQVLNINTDIVTPTDVSFDLNKLYTMLFYGGVVLILLVWV
SPLIRQLVNLSKATQAFGMGELQQRIPVRKTSYIGTIESEFNRMADRIQQLIDDNKLLSRAVSHDLKTPIARLRFGIEAL
EETQSEQLRVKYFQRLNRDLDTMEDLVMTLLSYARLDEANIQPDWQSIELNAWLLEKYQGQVYPDFSVELVSYPTALKIK
TDPKYLSMQVNNLLNNALRFGKAKIRLTLAVEEGATWLHVDDDGPGIDELESMQVIKPFVRGQHSRGNSGHGMGLAIVDR
IGYWMNAPLRIGRAPELGGARMSLKFKAEI
>Mature_430_residues
MKKLMTSLVLVVLVAIASLGWSISEFASLLDHDNDTQTPATHLAALKLLGGTLAQTLDNDSVNNQSIIANWNQLNSEQLS
LASEADFVLPSALKTAFYAGESLLLESDDGISLHYLLPKTGQVLNINTDIVTPTDVSFDLNKLYTMLFYGGVVLILLVWV
SPLIRQLVNLSKATQAFGMGELQQRIPVRKTSYIGTIESEFNRMADRIQQLIDDNKLLSRAVSHDLKTPIARLRFGIEAL
EETQSEQLRVKYFQRLNRDLDTMEDLVMTLLSYARLDEANIQPDWQSIELNAWLLEKYQGQVYPDFSVELVSYPTALKIK
TDPKYLSMQVNNLLNNALRFGKAKIRLTLAVEEGATWLHVDDDGPGIDELESMQVIKPFVRGQHSRGNSGHGMGLAIVDR
IGYWMNAPLRIGRAPELGGARMSLKFKAEI

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=276, Percent_Identity=34.7826086956522, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1789808, Length=255, Percent_Identity=31.7647058823529, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1790346, Length=211, Percent_Identity=27.0142180094787, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790551, Length=284, Percent_Identity=26.7605633802817, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788393, Length=275, Percent_Identity=22.9090909090909, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790861, Length=215, Percent_Identity=26.5116279069767, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081816, Length=108, Percent_Identity=35.1851851851852, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788279, Length=277, Percent_Identity=24.9097472924188, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788549, Length=233, Percent_Identity=24.0343347639485, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48035; Mature: 48035

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLMTSLVLVVLVAIASLGWSISEFASLLDHDNDTQTPATHLAALKLLGGTLAQTLDND
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
SVNNQSIIANWNQLNSEQLSLASEADFVLPSALKTAFYAGESLLLESDDGISLHYLLPKT
CCCCCEEEECHHHCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCC
GQVLNINTDIVTPTDVSFDLNKLYTMLFYGGVVLILLVWVSPLIRQLVNLSKATQAFGMG
CCEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
ELQQRIPVRKTSYIGTIESEFNRMADRIQQLIDDNKLLSRAVSHDLKTPIARLRFGIEAL
HHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EETQSEQLRVKYFQRLNRDLDTMEDLVMTLLSYARLDEANIQPDWQSIELNAWLLEKYQG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHCC
QVYPDFSVELVSYPTALKIKTDPKYLSMQVNNLLNNALRFGKAKIRLTLAVEEGATWLHV
CCCCCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCEEEEE
DDDGPGIDELESMQVIKPFVRGQHSRGNSGHGMGLAIVDRIGYWMNAPLRIGRAPELGGA
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCC
RMSLKFKAEI
EEEEEEEECC
>Mature Secondary Structure
MKKLMTSLVLVVLVAIASLGWSISEFASLLDHDNDTQTPATHLAALKLLGGTLAQTLDND
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
SVNNQSIIANWNQLNSEQLSLASEADFVLPSALKTAFYAGESLLLESDDGISLHYLLPKT
CCCCCEEEECHHHCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCC
GQVLNINTDIVTPTDVSFDLNKLYTMLFYGGVVLILLVWVSPLIRQLVNLSKATQAFGMG
CCEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
ELQQRIPVRKTSYIGTIESEFNRMADRIQQLIDDNKLLSRAVSHDLKTPIARLRFGIEAL
HHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EETQSEQLRVKYFQRLNRDLDTMEDLVMTLLSYARLDEANIQPDWQSIELNAWLLEKYQG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHCC
QVYPDFSVELVSYPTALKIKTDPKYLSMQVNNLLNNALRFGKAKIRLTLAVEEGATWLHV
CCCCCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCEEEEE
DDDGPGIDELESMQVIKPFVRGQHSRGNSGHGMGLAIVDRIGYWMNAPLRIGRAPELGGA
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCC
RMSLKFKAEI
EEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]