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The map label for this gene is gcvT [H]

Identifier: 126172866

GI number: 126172866

Start: 702382

End: 703476

Strand: Direct

Name: gcvT [H]

Synonym: Sbal_0617

Alternate gene names: 126172866

Gene position: 702382-703476 (Clockwise)

Preceding gene: 126172865

Following gene: 126172867

Centisome position: 13.7

GC content: 50.41

Gene sequence:

>1095_bases
ATGGCTAACAAAACTATTCTGTTTAACAAGCACTTAGAATCAAACGCTAAGATGGTCGACTTCCACGGTTGGGACATGCC
TCTCAACTATGGTTCACAAATCGAAGAACACAATGCAGTGCGTCAAGACGCGGGTATGTTCGACGTTTCCCACATGACTG
TGGTTGATGTGATTGGTAACGACGCTTGTGCATTTCTGCGTAAGTTGCTGGCAAACGATGTGGCTAAGCTTAAAGTTCCA
GGTAAAGCCTTATACGGCGGCATGTTAGACGAAAATGCTGGCGTCATCGACGACCTCATCACTTACTACCTCACTGACAC
TAATTACCGCGTGGTAGTGAACTCAGCGACCCGCGAAAAAGATCTCGCTTGGATCGCCAAGCAATCCCAAGGTTTTGATG
TCACTGTGACTGAGCGTCCCGAGCTGGCGATGATCGCCGTTCAAGGTCCTAACGCTAAAGCGAAAGCCGCTGCCGTGCTC
AGTGCCGAGCAAAACGCCGCCATCGAAGGCATGAAACCTTTCTTCGGTAAGCAAGCCGGTTCTCTGTTTATTGCGACTAC
GGGTTACACAGGCGAAGCGGGCTATGAAATTATCGTCCCAGAAAACGAAGCAGAGGCCATGTGGCAAGCATTGTTAGATC
AAGGTGTTAAACCTTGTGGTCTCGGTGCCCGTGACACTCTGCGCCTCGAAGCCGGTATGAATCTTTACGGCTTAGACATG
GACGAAACCATCAACCCATTGGCCGCCAACATGGGCTGGACCATCGCATGGGAACCGAGCGACCGTGACTTTATCGGCCG
TAAAGCCCTCGAAACACTTCGCGATGCCGGAACCGACAAACTTGTTGGTCTAGTGATGGAAGAAAAGGGCGTGTTACGCC
ATGATATGCCAGTATTTTTCACCGACTCAGCCGGTGTTGAGCACCAAGGCGTGATTACCAGCGGTACTTTCTCGCCAACA
TTGGGCTATTCTATTGCGATGGCGCGTGTTCCTAACTCGATTGGGGATACGGCGGAAGTCGAAATGCGTAAAAAACGTGT
GGCTGTTAGAGTGGTAGCGCCAAACTTTGTGCGCAACGGTAAACAAGCATTTTAA

Upstream 100 bases:

>100_bases
TAAACATTGGCAAATCGCTGCAATAGCCAGATATTTAACCGGATTGATATTACCCTACACTAGGCAGAGACCTGAAAAAG
GCCGCAAAAAAGGGATAACA

Downstream 100 bases:

>100_bases
AAAAAACGGAACAAGGAACAAGAACAATGAGCAATATTCCGACAGAACTGAAATACGCCTCTTCACACGAATGGATCCGC
AAGGAAGAAGACGGCAGCTA

Product: glycine cleavage system aminomethyltransferase T

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MANKTILFNKHLESNAKMVDFHGWDMPLNYGSQIEEHNAVRQDAGMFDVSHMTVVDVIGNDACAFLRKLLANDVAKLKVP
GKALYGGMLDENAGVIDDLITYYLTDTNYRVVVNSATREKDLAWIAKQSQGFDVTVTERPELAMIAVQGPNAKAKAAAVL
SAEQNAAIEGMKPFFGKQAGSLFIATTGYTGEAGYEIIVPENEAEAMWQALLDQGVKPCGLGARDTLRLEAGMNLYGLDM
DETINPLAANMGWTIAWEPSDRDFIGRKALETLRDAGTDKLVGLVMEEKGVLRHDMPVFFTDSAGVEHQGVITSGTFSPT
LGYSIAMARVPNSIGDTAEVEMRKKRVAVRVVAPNFVRNGKQAF

Sequences:

>Translated_364_residues
MANKTILFNKHLESNAKMVDFHGWDMPLNYGSQIEEHNAVRQDAGMFDVSHMTVVDVIGNDACAFLRKLLANDVAKLKVP
GKALYGGMLDENAGVIDDLITYYLTDTNYRVVVNSATREKDLAWIAKQSQGFDVTVTERPELAMIAVQGPNAKAKAAAVL
SAEQNAAIEGMKPFFGKQAGSLFIATTGYTGEAGYEIIVPENEAEAMWQALLDQGVKPCGLGARDTLRLEAGMNLYGLDM
DETINPLAANMGWTIAWEPSDRDFIGRKALETLRDAGTDKLVGLVMEEKGVLRHDMPVFFTDSAGVEHQGVITSGTFSPT
LGYSIAMARVPNSIGDTAEVEMRKKRVAVRVVAPNFVRNGKQAF
>Mature_363_residues
ANKTILFNKHLESNAKMVDFHGWDMPLNYGSQIEEHNAVRQDAGMFDVSHMTVVDVIGNDACAFLRKLLANDVAKLKVPG
KALYGGMLDENAGVIDDLITYYLTDTNYRVVVNSATREKDLAWIAKQSQGFDVTVTERPELAMIAVQGPNAKAKAAAVLS
AEQNAAIEGMKPFFGKQAGSLFIATTGYTGEAGYEIIVPENEAEAMWQALLDQGVKPCGLGARDTLRLEAGMNLYGLDMD
ETINPLAANMGWTIAWEPSDRDFIGRKALETLRDAGTDKLVGLVMEEKGVLRHDMPVFFTDSAGVEHQGVITSGTFSPTL
GYSIAMARVPNSIGDTAEVEMRKKRVAVRVVAPNFVRNGKQAF

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0404

COG function: function code E; Glycine cleavage system T protein (aminomethyltransferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI44662838, Length=373, Percent_Identity=34.3163538873995, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI257796258, Length=344, Percent_Identity=34.8837209302326, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI257796254, Length=357, Percent_Identity=31.3725490196078, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI257796256, Length=307, Percent_Identity=33.5504885993485, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI24797151, Length=385, Percent_Identity=24.4155844155844, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI197927446, Length=295, Percent_Identity=27.1186440677966, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI21361378, Length=295, Percent_Identity=27.1186440677966, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1789272, Length=361, Percent_Identity=67.8670360110803, Blast_Score=519, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI17560118, Length=379, Percent_Identity=33.509234828496, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71994045, Length=347, Percent_Identity=25.3602305475504, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71994052, Length=347, Percent_Identity=25.3602305475504, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320222, Length=343, Percent_Identity=35.2769679300292, Blast_Score=156, Evalue=4e-39,
Organism=Drosophila melanogaster, GI20129441, Length=377, Percent_Identity=32.8912466843501, Blast_Score=168, Evalue=6e-42,
Organism=Drosophila melanogaster, GI28571104, Length=262, Percent_Identity=24.4274809160305, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI20130091, Length=395, Percent_Identity=22.7848101265823, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 39657; Mature: 39526

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANKTILFNKHLESNAKMVDFHGWDMPLNYGSQIEEHNAVRQDAGMFDVSHMTVVDVIGN
CCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCEEECCEEEEEECCC
DACAFLRKLLANDVAKLKVPGKALYGGMLDENAGVIDDLITYYLTDTNYRVVVNSATREK
HHHHHHHHHHHCCHHEEECCCHHHCCCCCCCCCCHHHHHHHEEEECCCEEEEEECCCCCC
DLAWIAKQSQGFDVTVTERPELAMIAVQGPNAKAKAAAVLSAEQNAAIEGMKPFFGKQAG
HHHEEEECCCCCEEEEECCCCEEEEEEECCCCCCHHEEEEECCCCCCCCCCCCCCCCCCC
SLFIATTGYTGEAGYEIIVPENEAEAMWQALLDQGVKPCGLGARDTLRLEAGMNLYGLDM
CEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEECCH
DETINPLAANMGWTIAWEPSDRDFIGRKALETLRDAGTDKLVGLVMEEKGVLRHDMPVFF
HHHCCHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHCCCCEEE
TDSAGVEHQGVITSGTFSPTLGYSIAMARVPNSIGDTAEVEMRKKRVAVRVVAPNFVRNG
ECCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHHHCEEEEEEECCHHHCCC
KQAF
CCCC
>Mature Secondary Structure 
ANKTILFNKHLESNAKMVDFHGWDMPLNYGSQIEEHNAVRQDAGMFDVSHMTVVDVIGN
CCCEEEEECCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCEEECCEEEEEECCC
DACAFLRKLLANDVAKLKVPGKALYGGMLDENAGVIDDLITYYLTDTNYRVVVNSATREK
HHHHHHHHHHHCCHHEEECCCHHHCCCCCCCCCCHHHHHHHEEEECCCEEEEEECCCCCC
DLAWIAKQSQGFDVTVTERPELAMIAVQGPNAKAKAAAVLSAEQNAAIEGMKPFFGKQAG
HHHEEEECCCCCEEEEECCCCEEEEEEECCCCCCHHEEEEECCCCCCCCCCCCCCCCCCC
SLFIATTGYTGEAGYEIIVPENEAEAMWQALLDQGVKPCGLGARDTLRLEAGMNLYGLDM
CEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEECCH
DETINPLAANMGWTIAWEPSDRDFIGRKALETLRDAGTDKLVGLVMEEKGVLRHDMPVFF
HHHCCHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHCCCCEEE
TDSAGVEHQGVITSGTFSPTLGYSIAMARVPNSIGDTAEVEMRKKRVAVRVVAPNFVRNG
ECCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHHHCEEEEEEECCHHHCCC
KQAF
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA