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The map label for this gene is visC [H]

Identifier: 126172865

GI number: 126172865

Start: 700708

End: 701931

Strand: Direct

Name: visC [H]

Synonym: Sbal_0616

Alternate gene names: 126172865

Gene position: 700708-701931 (Clockwise)

Preceding gene: 126172864

Following gene: 126172866

Centisome position: 13.67

GC content: 53.43

Gene sequence:

>1224_bases
ATGTTAAGTTCACAAGCCTATGACATCGCCATTGTGGGTGGCGGCATGGTGGGACTCGCCACCGCGATTGGATTGGCACA
GGCCAATCTTAATGTCGTCGTTATCGATGCGGGCCACACGGATGCCGTTGTCGGCGAGCCGCGCCTGCGGGTGAGCGCCA
TCAATAAGGCGAGTCAGCGCTTGTTAGAAAACTTAGGTGCATGGTCTTATTTATACACTTCCCGCGCCACGCCTTATCAA
AAAATGGCGGTGTGGGATAAAGACGGTTTCGGCAAAATTGCCTTTGACGCCAACAGCATCAGCGAAACCAGTCTCGGCGC
GATTATCGAAAACGATGCCATTAGCTTTGCGCTGGCGAAACGCGTCGCTGAGTTTGACAATATCACTCATATTGAAAACC
AACGCTTAGAACGCATTGCCTTTGGCGAGCGCGAAGCTTGGCTGACCCTCGCCAATGGTGCCCATTCCCAAATTGAAAGT
GTGAGTGCTGCCTTGGTGATCGCTGCCGATGGCGCCAACTCTTGGGTGCGTGAGCAATGCAAGATCCCGCTGACATTTTG
GGATTACGGCCACCACGCAATTGTCGCAACGATCCGCACCGAAATGCCGCACCTTGCCACCGCCCGCCAAGTGTTTTTAA
AGGACGGCCCGTTAGCATTTTTACCTTTGTATGAAGACAATCTCTGCTCCATCGTTTGGTCGGTGCCGCCTGAGCGCGCC
AATGAATTATTAGCGATGGACAAAGTGCAATTCGAGCGCAACTTAACCGCGGCGTTCGATGGTCGTTTGGGGATTTGTCA
GCTGGAAAGCGAGCGCCAAGCTTTCCCATTACGGATGCGCTACGCCCGCCATTTTGCCCGCCACCGTTTAGTGTTGGCAG
GCGATGCCGCCCACACTATCCATCCGCTGGCTGGCCAAGGGGTGAACCTTGGCTTTTTAGATGCAGCCAGCATTATCGAA
GTCATCAGCGAATTACAGCAAGCGGGTAAAGATATCGGCGATTATGCCCAGCTGCGCGCGCTGGAACGTTGGCGTAAAGC
CGATGCGATGGAGATGATCGCGGCGATGGAAGGCTTTAAGCGCTTATTCGAAGGGACGAATCCGCTGAAAAAAGCGATCC
GCGATCTGGGCTTAAATCTGGTTGATAATGTCGCTGGGCTGAAAACAGTGTTCATACAACAGGCCATGGGCAATAAGTCG
GCGCTGCCTAAGTTATGTCGTTAG

Upstream 100 bases:

>100_bases
CTTGGTTTCCGCCACTTAAAACCCCCGTTGCTCAAAAGGCGATGGGCTGGAAATAACTCGCTTTTCATTACTGGTATCGC
AACGCGAAAAGGATGTACCC

Downstream 100 bases:

>100_bases
CCTCGGTTGCGCTAATGTGATCAGAATTGCCGCTAATATCAGCACATTGACTACAAGCTGCGCAAATCTGGTCTTCGCAT
GTAAAAAAATTACATGTTAA

Product: UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MLSSQAYDIAIVGGGMVGLATAIGLAQANLNVVVIDAGHTDAVVGEPRLRVSAINKASQRLLENLGAWSYLYTSRATPYQ
KMAVWDKDGFGKIAFDANSISETSLGAIIENDAISFALAKRVAEFDNITHIENQRLERIAFGEREAWLTLANGAHSQIES
VSAALVIAADGANSWVREQCKIPLTFWDYGHHAIVATIRTEMPHLATARQVFLKDGPLAFLPLYEDNLCSIVWSVPPERA
NELLAMDKVQFERNLTAAFDGRLGICQLESERQAFPLRMRYARHFARHRLVLAGDAAHTIHPLAGQGVNLGFLDAASIIE
VISELQQAGKDIGDYAQLRALERWRKADAMEMIAAMEGFKRLFEGTNPLKKAIRDLGLNLVDNVAGLKTVFIQQAMGNKS
ALPKLCR

Sequences:

>Translated_407_residues
MLSSQAYDIAIVGGGMVGLATAIGLAQANLNVVVIDAGHTDAVVGEPRLRVSAINKASQRLLENLGAWSYLYTSRATPYQ
KMAVWDKDGFGKIAFDANSISETSLGAIIENDAISFALAKRVAEFDNITHIENQRLERIAFGEREAWLTLANGAHSQIES
VSAALVIAADGANSWVREQCKIPLTFWDYGHHAIVATIRTEMPHLATARQVFLKDGPLAFLPLYEDNLCSIVWSVPPERA
NELLAMDKVQFERNLTAAFDGRLGICQLESERQAFPLRMRYARHFARHRLVLAGDAAHTIHPLAGQGVNLGFLDAASIIE
VISELQQAGKDIGDYAQLRALERWRKADAMEMIAAMEGFKRLFEGTNPLKKAIRDLGLNLVDNVAGLKTVFIQQAMGNKS
ALPKLCR
>Mature_407_residues
MLSSQAYDIAIVGGGMVGLATAIGLAQANLNVVVIDAGHTDAVVGEPRLRVSAINKASQRLLENLGAWSYLYTSRATPYQ
KMAVWDKDGFGKIAFDANSISETSLGAIIENDAISFALAKRVAEFDNITHIENQRLERIAFGEREAWLTLANGAHSQIES
VSAALVIAADGANSWVREQCKIPLTFWDYGHHAIVATIRTEMPHLATARQVFLKDGPLAFLPLYEDNLCSIVWSVPPERA
NELLAMDKVQFERNLTAAFDGRLGICQLESERQAFPLRMRYARHFARHRLVLAGDAAHTIHPLAGQGVNLGFLDAASIIE
VISELQQAGKDIGDYAQLRALERWRKADAMEMIAAMEGFKRLFEGTNPLKKAIRDLGLNLVDNVAGLKTVFIQQAMGNKS
ALPKLCR

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=382, Percent_Identity=32.7225130890052, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI32967307, Length=348, Percent_Identity=32.4712643678161, Blast_Score=150, Evalue=3e-36,
Organism=Escherichia coli, GI1789273, Length=405, Percent_Identity=53.3333333333333, Blast_Score=421, Evalue=1e-119,
Organism=Escherichia coli, GI1786883, Length=399, Percent_Identity=35.3383458646617, Blast_Score=212, Evalue=3e-56,
Organism=Escherichia coli, GI1789274, Length=395, Percent_Identity=30.379746835443, Blast_Score=164, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI25146631, Length=440, Percent_Identity=29.0909090909091, Blast_Score=163, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6321694, Length=463, Percent_Identity=26.3498920086393, Blast_Score=134, Evalue=3e-32,
Organism=Drosophila melanogaster, GI19920760, Length=440, Percent_Identity=30.4545454545455, Blast_Score=162, Evalue=6e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 44665; Mature: 44665

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSSQAYDIAIVGGGMVGLATAIGLAQANLNVVVIDAGHTDAVVGEPRLRVSAINKASQR
CCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
LLENLGAWSYLYTSRATPYQKMAVWDKDGFGKIAFDANSISETSLGAIIENDAISFALAK
HHHHCCCCEEEHCCCCCCHHHEEEECCCCCCEEEECCCCCCCHHHHHEEECCHHHHHHHH
RVAEFDNITHIENQRLERIAFGEREAWLTLANGAHSQIESVSAALVIAADGANSWVREQC
HHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCEEEEEEECCCCHHHHHHC
KIPLTFWDYGHHAIVATIRTEMPHLATARQVFLKDGPLAFLPLYEDNLCSIVWSVPPERA
CCCEEEECCCCEEEEEEEHHCCCHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCHHHH
NELLAMDKVQFERNLTAAFDGRLGICQLESERQAFPLRMRYARHFARHRLVLAGDAAHTI
HHHHHHHHHHHHCCCCEEECCCEEEEEECCCCCCCHHHHHHHHHHHHCEEEEECCCCHHC
HPLAGQGVNLGFLDAASIIEVISELQQAGKDIGDYAQLRALERWRKADAMEMIAAMEGFK
CCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLFEGTNPLKKAIRDLGLNLVDNVAGLKTVFIQQAMGNKSALPKLCR
HHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCC
>Mature Secondary Structure
MLSSQAYDIAIVGGGMVGLATAIGLAQANLNVVVIDAGHTDAVVGEPRLRVSAINKASQR
CCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
LLENLGAWSYLYTSRATPYQKMAVWDKDGFGKIAFDANSISETSLGAIIENDAISFALAK
HHHHCCCCEEEHCCCCCCHHHEEEECCCCCCEEEECCCCCCCHHHHHEEECCHHHHHHHH
RVAEFDNITHIENQRLERIAFGEREAWLTLANGAHSQIESVSAALVIAADGANSWVREQC
HHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCEEEEEEECCCCHHHHHHC
KIPLTFWDYGHHAIVATIRTEMPHLATARQVFLKDGPLAFLPLYEDNLCSIVWSVPPERA
CCCEEEECCCCEEEEEEEHHCCCHHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCHHHH
NELLAMDKVQFERNLTAAFDGRLGICQLESERQAFPLRMRYARHFARHRLVLAGDAAHTI
HHHHHHHHHHHHCCCCEEECCCEEEEEECCCCCCCHHHHHHHHHHHHCEEEEECCCCHHC
HPLAGQGVNLGFLDAASIIEVISELQQAGKDIGDYAQLRALERWRKADAMEMIAAMEGFK
CCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLFEGTNPLKKAIRDLGLNLVDNVAGLKTVFIQQAMGNKSALPKLCR
HHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]