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The map label for this gene is mlhB [H]

Identifier: 126172819

GI number: 126172819

Start: 644402

End: 645313

Strand: Direct

Name: mlhB [H]

Synonym: Sbal_0570

Alternate gene names: 126172819

Gene position: 644402-645313 (Clockwise)

Preceding gene: 126172818

Following gene: 126172820

Centisome position: 12.57

GC content: 49.23

Gene sequence:

>912_bases
ATGCCAAGCTGGCAAGCATCTGTACTGAATACTATTTTATCTTATGTCGCTAGGCCATCCATCAGTCGCGGCAAGGCCAA
AGTCCCTCTAGCGCAAGTGCGTAAAAAGTTGCTTGATCTCGATAAACGTTGGCTTCCTTGGCCGGATAAGTTAGTTAGTG
CCACCATCCCTTTGCAACACTCTAGCTTGCTGCACTATGTGCTTCTCAATCAACAAACTCGCCTTGGCAATCTGTTTTAT
ATCCGAGGCGGAGGTTTTTGTTTTAAAACGCCCCATGCCCACGCAAGATTGATCGCGGATATCAGCCAGCGTTGTAAATT
GGATGCCTATATTCCTGATTATCGTCTCGCACCTGAGCATCCTTTTCCTGCGCCATTTGATGATGTGCTTGAAGCCTATA
AGCGATTAATCGCGCTTAAGGGCGCTGAGAATGTGATTCTCATGGGCGACTCTGCTGGCGGCAATTTAGCCCTGAGTTTG
TTGCTGGAATTAAAGCGTTTAGCCCTGCCTTTGCCGACGGCTTGTATCTTGTTATCGCCCGCGTTGGATTTAGCACTAAC
GGGGGATACTGAGTTGATACTCGCGGCTGACGATCCCTTCTTCACCATCGAAGCTTTGCTGCGTTTACGTGGCGCTTATC
TTGCGGGTGCCGACCCCATGTCAGCAAAAGTTTCACCCTTGCAGGGGGACTTGGCAGATCTGCCGCCCATCTTAGTGATT
GCGGGTACGCGGGAGCTGTTATTGCAGGATTCTGAGCGCCTAGTCGCTCAAGTCAAAGCTAGCGGTGGCGAGATAACGGG
CTGTTTTTACCCTAACATGCCCCATGTGTTTCCCTTGTTCAATTTATTGCCCGAAGCCCTTGAAGTGAGGTCGAAAATTA
GCCATTTTGTGCTTTCACACTTGATTCGTTAA

Upstream 100 bases:

>100_bases
CTGCGCTTAAAAGCACAGAATTATAGGAAGTTAGATCTGCTGTAGTCCACGACCTGCGACTTGAGCGTCGGGATGGCGGC
GTTTAAGTAGAGGAAGGGAT

Downstream 100 bases:

>100_bases
AATGGTGTAGTTATTCACATTCAGTGAATAGCTAGCAAAATGAGGGGTAAATAACTTTTTTTATGACTAATTATGCTGAA
AGCCACGGGCATAACCGCTT

Product: alpha/beta hydrolase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MPSWQASVLNTILSYVARPSISRGKAKVPLAQVRKKLLDLDKRWLPWPDKLVSATIPLQHSSLLHYVLLNQQTRLGNLFY
IRGGGFCFKTPHAHARLIADISQRCKLDAYIPDYRLAPEHPFPAPFDDVLEAYKRLIALKGAENVILMGDSAGGNLALSL
LLELKRLALPLPTACILLSPALDLALTGDTELILAADDPFFTIEALLRLRGAYLAGADPMSAKVSPLQGDLADLPPILVI
AGTRELLLQDSERLVAQVKASGGEITGCFYPNMPHVFPLFNLLPEALEVRSKISHFVLSHLIR

Sequences:

>Translated_303_residues
MPSWQASVLNTILSYVARPSISRGKAKVPLAQVRKKLLDLDKRWLPWPDKLVSATIPLQHSSLLHYVLLNQQTRLGNLFY
IRGGGFCFKTPHAHARLIADISQRCKLDAYIPDYRLAPEHPFPAPFDDVLEAYKRLIALKGAENVILMGDSAGGNLALSL
LLELKRLALPLPTACILLSPALDLALTGDTELILAADDPFFTIEALLRLRGAYLAGADPMSAKVSPLQGDLADLPPILVI
AGTRELLLQDSERLVAQVKASGGEITGCFYPNMPHVFPLFNLLPEALEVRSKISHFVLSHLIR
>Mature_302_residues
PSWQASVLNTILSYVARPSISRGKAKVPLAQVRKKLLDLDKRWLPWPDKLVSATIPLQHSSLLHYVLLNQQTRLGNLFYI
RGGGFCFKTPHAHARLIADISQRCKLDAYIPDYRLAPEHPFPAPFDDVLEAYKRLIALKGAENVILMGDSAGGNLALSLL
LELKRLALPLPTACILLSPALDLALTGDTELILAADDPFFTIEALLRLRGAYLAGADPMSAKVSPLQGDLADLPPILVIA
GTRELLLQDSERLVAQVKASGGEITGCFYPNMPHVFPLFNLLPEALEVRSKISHFVLSHLIR

Specific function: Lactone hydrolase that is required for the degradation of monocyclic monoterpenes such as menthol and carvone. Catalyzes the ring opening of lactones formed during degradation of monocyclic monoterpenes. Can hydrolyze epsilon-caprolactone, the lactone der

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17567059, Length=141, Percent_Identity=31.2056737588652, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.83 [H]

Molecular weight: Translated: 33303; Mature: 33171

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSWQASVLNTILSYVARPSISRGKAKVPLAQVRKKLLDLDKRWLPWPDKLVSATIPLQH
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHEEECCCCH
SSLLHYVLLNQQTRLGNLFYIRGGGFCFKTPHAHARLIADISQRCKLDAYIPDYRLAPEH
HHHHHHHHHCCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHCEECCCCCCCCCCCCC
PFPAPFDDVLEAYKRLIALKGAENVILMGDSAGGNLALSLLLELKRLALPLPTACILLSP
CCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHCC
ALDLALTGDTELILAADDPFFTIEALLRLRGAYLAGADPMSAKVSPLQGDLADLPPILVI
CCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCEEEE
AGTRELLLQDSERLVAQVKASGGEITGCFYPNMPHVFPLFNLLPEALEVRSKISHFVLSH
ECCHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIR
HCC
>Mature Secondary Structure 
PSWQASVLNTILSYVARPSISRGKAKVPLAQVRKKLLDLDKRWLPWPDKLVSATIPLQH
CCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHEEECCCCH
SSLLHYVLLNQQTRLGNLFYIRGGGFCFKTPHAHARLIADISQRCKLDAYIPDYRLAPEH
HHHHHHHHHCCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHCEECCCCCCCCCCCCC
PFPAPFDDVLEAYKRLIALKGAENVILMGDSAGGNLALSLLLELKRLALPLPTACILLSP
CCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHCC
ALDLALTGDTELILAADDPFFTIEALLRLRGAYLAGADPMSAKVSPLQGDLADLPPILVI
CCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCEEEE
AGTRELLLQDSERLVAQVKASGGEITGCFYPNMPHVFPLFNLLPEALEVRSKISHFVLSH
ECCHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIR
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA