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The map label for this gene is rnhA

Identifier: 125625302

GI number: 125625302

Start: 2508690

End: 2509568

Strand: Direct

Name: rnhA

Synonym: llmg_2549

Alternate gene names: 125625302

Gene position: 2508690-2509568 (Clockwise)

Preceding gene: 125625301

Following gene: 125625303

Centisome position: 99.18

GC content: 34.7

Gene sequence:

>879_bases
ATGAATATTGTCCTAAAATTAAGCTCTAATGCCTGTCAGCAACTCTCTGAAAAATATAAATCTTACGAGCAAACTTCTAA
AAATCCTTATATTCGCTTTTTTGCTAAAGTTGGAAAAACTTCTATTTCTGTTTATACATCTGGAAAAGTAGTCTTTCAAG
GAAGTGATGCTGAAAAAATTGCAAGTGAATTTGGACATGTTGCTCAAGTTGTTCCTAAAAAACAAACTAATCTTATTGGG
ACTGACGAGGTAGGAAATGGTTCATATTTTGGTGGCTTAATGGTTACTGCAAGTTTTGTCAGTGATAATCATTTGAAATT
TTTAAAAGAAATGGGTGTCGCTGATTCTAAAAAATTAACTGACGAAAAAATTTGTCAGATTGCCCCCAAATTGATAGAGG
AGATTCCTCATGTTGCCTTGGTTGTTGAGCCTGAGAAGTATAACGAGGTGATTGCTTCGGGCTATAATGCTGTCAGCATC
AAGGTTGCCTTACATAATCAAGCAATTTATCTCCTTGAAAAGCAACTCGGTAGCCAGCCTGAAAGTATTGTTATCGATGC
TTTCACAACCGAAGCAAATTATAAAAAATATGTTAGCGCAGAAAAAAATCACCCACTGACAAACATAACTTTACTGACAA
AAGCTGAAGATCAATTTTTAGCTGTTGCAGTTAGTTCAATTATTTCTCGTTATAAGTTTTTGGAAAATCTCAAAAAGTTA
TCAAAAGAATCTGGCTTCACTTTACCCAGTGGCGCAGGAAATTTGTCTGACAAAGTTGCTGCTCAAATCATTAAGAGTAA
AGGGATTGATGCTCTGAATCACTTAGCTAAATTACATTTTGCCAATACACAAAAAGCGATGAAAATCGCTCAATTATAG

Upstream 100 bases:

>100_bases
TTTTATTAGAGGTTTGGTATAATAGGTTTTAATAAGAAATATTTTAAACAAATAGTTGGATTCTTATTCGCGAACCTCTT
ATTTGTGGTAGAATAATCTT

Downstream 100 bases:

>100_bases
AAAGTAATAATATGATGAAATTTTTAAAAGAATGGGGATTATTTATCTTTATAATTGCCGCTGTCCTTCTCTCGCGCGTC
TTTATTTGGTCACTAGTTGT

Product: ribonuclease HIII

Products: NA

Alternate protein names: RNase HIII

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MNIVLKLSSNACQQLSEKYKSYEQTSKNPYIRFFAKVGKTSISVYTSGKVVFQGSDAEKIASEFGHVAQVVPKKQTNLIG
TDEVGNGSYFGGLMVTASFVSDNHLKFLKEMGVADSKKLTDEKICQIAPKLIEEIPHVALVVEPEKYNEVIASGYNAVSI
KVALHNQAIYLLEKQLGSQPESIVIDAFTTEANYKKYVSAEKNHPLTNITLLTKAEDQFLAVAVSSIISRYKFLENLKKL
SKESGFTLPSGAGNLSDKVAAQIIKSKGIDALNHLAKLHFANTQKAMKIAQL

Sequences:

>Translated_292_residues
MNIVLKLSSNACQQLSEKYKSYEQTSKNPYIRFFAKVGKTSISVYTSGKVVFQGSDAEKIASEFGHVAQVVPKKQTNLIG
TDEVGNGSYFGGLMVTASFVSDNHLKFLKEMGVADSKKLTDEKICQIAPKLIEEIPHVALVVEPEKYNEVIASGYNAVSI
KVALHNQAIYLLEKQLGSQPESIVIDAFTTEANYKKYVSAEKNHPLTNITLLTKAEDQFLAVAVSSIISRYKFLENLKKL
SKESGFTLPSGAGNLSDKVAAQIIKSKGIDALNHLAKLHFANTQKAMKIAQL
>Mature_292_residues
MNIVLKLSSNACQQLSEKYKSYEQTSKNPYIRFFAKVGKTSISVYTSGKVVFQGSDAEKIASEFGHVAQVVPKKQTNLIG
TDEVGNGSYFGGLMVTASFVSDNHLKFLKEMGVADSKKLTDEKICQIAPKLIEEIPHVALVVEPEKYNEVIASGYNAVSI
KVALHNQAIYLLEKQLGSQPESIVIDAFTTEANYKKYVSAEKNHPLTNITLLTKAEDQFLAVAVSSIISRYKFLENLKKL
SKESGFTLPSGAGNLSDKVAAQIIKSKGIDALNHLAKLHFANTQKAMKIAQL

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG1039

COG function: function code L; Ribonuclease HIII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family. RnhC subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH3_LACLM (A2RP65)

Other databases:

- EMBL:   AM406671
- RefSeq:   YP_001033785.1
- STRING:   A2RP65
- GeneID:   4798110
- GenomeReviews:   AM406671_GR
- KEGG:   llm:llmg_2549
- eggNOG:   COG1039
- HOGENOM:   HBG288559
- OMA:   ASIIARY
- ProtClustDB:   PRK00996
- GO:   GO:0005737
- HAMAP:   MF_00053
- InterPro:   IPR001352
- InterPro:   IPR004641
- InterPro:   IPR012337
- PIRSF:   PIRSF037748
- TIGRFAMs:   TIGR00716

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 32008; Mature: 32008

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIVLKLSSNACQQLSEKYKSYEQTSKNPYIRFFAKVGKTSISVYTSGKVVFQGSDAEKI
CCEEEEECCHHHHHHHHHHHHHHHCCCCCCEEHHHHHCCCEEEEEECCEEEEECCCHHHH
ASEFGHVAQVVPKKQTNLIGTDEVGNGSYFGGLMVTASFVSDNHLKFLKEMGVADSKKLT
HHHHHHHHHHCCCHHCCCCCCCCCCCCCEECHHHEEEHHHCCHHHHHHHHCCCCCCCCCC
DEKICQIAPKLIEEIPHVALVVEPEKYNEVIASGYNAVSIKVALHNQAIYLLEKQLGSQP
HHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHCCCCEEEEEEEECCCHHEEEHHHHCCCC
ESIVIDAFTTEANYKKYVSAEKNHPLTNITLLTKAEDQFLAVAVSSIISRYKFLENLKKL
CEEEEEEEECCCCHHHHHCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
SKESGFTLPSGAGNLSDKVAAQIIKSKGIDALNHLAKLHFANTQKAMKIAQL
HHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MNIVLKLSSNACQQLSEKYKSYEQTSKNPYIRFFAKVGKTSISVYTSGKVVFQGSDAEKI
CCEEEEECCHHHHHHHHHHHHHHHCCCCCCEEHHHHHCCCEEEEEECCEEEEECCCHHHH
ASEFGHVAQVVPKKQTNLIGTDEVGNGSYFGGLMVTASFVSDNHLKFLKEMGVADSKKLT
HHHHHHHHHHCCCHHCCCCCCCCCCCCCEECHHHEEEHHHCCHHHHHHHHCCCCCCCCCC
DEKICQIAPKLIEEIPHVALVVEPEKYNEVIASGYNAVSIKVALHNQAIYLLEKQLGSQP
HHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHCCCCEEEEEEEECCCHHEEEHHHHCCCC
ESIVIDAFTTEANYKKYVSAEKNHPLTNITLLTKAEDQFLAVAVSSIISRYKFLENLKKL
CEEEEEEEECCCCHHHHHCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
SKESGFTLPSGAGNLSDKVAAQIIKSKGIDALNHLAKLHFANTQKAMKIAQL
HHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA