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The map label for this gene is sipL [H]

Identifier: 125625303

GI number: 125625303

Start: 2509580

End: 2510206

Strand: Direct

Name: sipL [H]

Synonym: llmg_2550

Alternate gene names: 125625303

Gene position: 2509580-2510206 (Clockwise)

Preceding gene: 125625302

Following gene: 125625313

Centisome position: 99.21

GC content: 37.16

Gene sequence:

>627_bases
ATGATGAAATTTTTAAAAGAATGGGGATTATTTATCTTTATAATTGCCGCTGTCCTTCTCTCGCGCGTCTTTATTTGGTC
ACTAGTTGTCGTTGATGGCCATTCAATGGACCCTACTTTAGCCGATAAAGAAAGACTTGTAATTGTTAGAACGACAAAAA
TTAATCGTTTTGATATTGTAGTTGCTAAAGAAAACGCGGCTGATGGTTCAACCAAAGATATTGTCAAACGTGTCGTTGGG
ATGCCTGGGGACACTATAAAATTCGACCATGACCAACTTACTATCAATAATAAGGTTTATCCAGAAAACTATCTCAAAGA
CTATCAAAAACAATTGGCTGATGGTCAATTGGAAAAAACTTACGGGAACTATCCTTTGACAAAAGCATTAACTGATCAAA
ATCGTAGTTTATTTGTAAGCTTAGCTCAGAGCACCAAAGCTTTTACAACGGATAGTACTGGTAATCCAACCTTTACAGTC
AAAGTCCCTGACGGACAATACTTCTTGATGGGAGATAATCGTGTTGTGTCTCAAGATAGCCGAGCAGTTGGAAGTTTCAA
ACGTTCAGCGATTATTGGTGAAGCCAAATTACGAGTTTGGCCACTCAATAAAATTTCTTTCTTTTAA

Upstream 100 bases:

>100_bases
TTAAGAGTAAAGGGATTGATGCTCTGAATCACTTAGCTAAATTACATTTTGCCAATACACAAAAAGCGATGAAAATCGCT
CAATTATAGAAAGTAATAAT

Downstream 100 bases:

>100_bases
GTAAATAAGCAAAAAAGTTACTGACAGAATGTCTGTCAGTAACTTTTTTATTTGTCATTAAATATATTTCCCAATTGAAC
ATCAATTGAACGATTGGCAA

Product: SipL protein

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MMKFLKEWGLFIFIIAAVLLSRVFIWSLVVVDGHSMDPTLADKERLVIVRTTKINRFDIVVAKENAADGSTKDIVKRVVG
MPGDTIKFDHDQLTINNKVYPENYLKDYQKQLADGQLEKTYGNYPLTKALTDQNRSLFVSLAQSTKAFTTDSTGNPTFTV
KVPDGQYFLMGDNRVVSQDSRAVGSFKRSAIIGEAKLRVWPLNKISFF

Sequences:

>Translated_208_residues
MMKFLKEWGLFIFIIAAVLLSRVFIWSLVVVDGHSMDPTLADKERLVIVRTTKINRFDIVVAKENAADGSTKDIVKRVVG
MPGDTIKFDHDQLTINNKVYPENYLKDYQKQLADGQLEKTYGNYPLTKALTDQNRSLFVSLAQSTKAFTTDSTGNPTFTV
KVPDGQYFLMGDNRVVSQDSRAVGSFKRSAIIGEAKLRVWPLNKISFF
>Mature_208_residues
MMKFLKEWGLFIFIIAAVLLSRVFIWSLVVVDGHSMDPTLADKERLVIVRTTKINRFDIVVAKENAADGSTKDIVKRVVG
MPGDTIKFDHDQLTINNKVYPENYLKDYQKQLADGQLEKTYGNYPLTKALTDQNRSLFVSLAQSTKAFTTDSTGNPTFTV
KVPDGQYFLMGDNRVVSQDSRAVGSFKRSAIIGEAKLRVWPLNKISFF

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=241, Percent_Identity=27.3858921161826, Blast_Score=67, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 23478; Mature: 23478

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKFLKEWGLFIFIIAAVLLSRVFIWSLVVVDGHSMDPTLADKERLVIVRTTKINRFDIV
CCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCEEEEEECCCCEEEEE
VAKENAADGSTKDIVKRVVGMPGDTIKFDHDQLTINNKVYPENYLKDYQKQLADGQLEKT
EEECCCCCCCHHHHHHHHHCCCCCEEEECCCEEEECCEECCHHHHHHHHHHHCCCCHHHH
YGNYPLTKALTDQNRSLFVSLAQSTKAFTTDSTGNPTFTVKVPDGQYFLMGDNRVVSQDS
CCCCCCCHHHCCCCCEEEEEEECCCCEEECCCCCCCEEEEEECCCCEEEEECCEEECCCC
RAVGSFKRSAIIGEAKLRVWPLNKISFF
HHHHHHHHHEEECCCEEEEEECHHCCCC
>Mature Secondary Structure
MMKFLKEWGLFIFIIAAVLLSRVFIWSLVVVDGHSMDPTLADKERLVIVRTTKINRFDIV
CCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCEEEEEECCCCEEEEE
VAKENAADGSTKDIVKRVVGMPGDTIKFDHDQLTINNKVYPENYLKDYQKQLADGQLEKT
EEECCCCCCCHHHHHHHHHCCCCCEEEECCCEEEECCEECCHHHHHHHHHHHCCCCHHHH
YGNYPLTKALTDQNRSLFVSLAQSTKAFTTDSTGNPTFTVKVPDGQYFLMGDNRVVSQDS
CCCCCCCHHHCCCCCEEEEEEECCCCEEECCCCCCCEEEEEECCCCEEEEECCEEECCCC
RAVGSFKRSAIIGEAKLRVWPLNKISFF
HHHHHHHHHEEECCCEEEEEECHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9272867; 11463916 [H]