Click here to switch to the map view.

The map label for this gene is recG [H]

Identifier: 125625276

GI number: 125625276

Start: 2479373

End: 2481373

Strand: Reverse

Name: recG [H]

Synonym: llmg_2523

Alternate gene names: 125625276

Gene position: 2481373-2479373 (Counterclockwise)

Preceding gene: 125625277

Following gene: 125625275

Centisome position: 98.1

GC content: 39.03

Gene sequence:

>2001_bases
ATGAAATTAACAGATTCAGTGCAATTTTTAAAAGGTGTGGGGCCAAAGTCTGTGGAAAATTTCCATAAGTTAGGAATTTT
CACAGTTCAAGATTTACTGCTTTATTTCCCTTTTCGTTATGAAGATTTCGCAAGTCGCTCGGTTTTTGAACTTACTGACG
GAGAAAAAGCAACGATTATTGGAACGGTAGTGACCCCAGCTAATGTTCAGTATTACGGATTTAAACGTAATCGACTTTCA
TTTAAAATTAAAGAAGGTGAAGCCGTCGTTGCTGTCAGCTTTTTTAATCAACCCTATTTGGCTGATAAAGTGGAGGTTGG
AAAAGAAATTGCTGTTTATGGAAAATGGGAACAGACAAAGCAACAACTGATGGGAATGAAAGTTGTGGCTCAGGTGGACG
ATGGATTAGAACCTGTTTATCATTTGACAGCGGGTATGAAACAAAGTCAATTGGTCAAAGTGATTCATCAAGTTTTTGAA
TCAGGGCTTCTGTCAGAATTACCTGAGAACTTACCAGAATTTTTGATAGAAAAATATCGTCTGATGAACCGGCAAGAAGC
CGTTTTGGCCATGCATTTTCCTGAAGATATGGCGGCTCATAAACAGGCATTGCGACGTGTAAAATTTGAAGAATTATTCA
TGTTTCAGTTGAAATTGCAGGCACTGAAAAATAAAGAAAAATCAGGACGAGCAGGTTTACAAGTTATATTTGAGCAAGAA
GAAATTGATAAAAAAATTTCGGACTTACCTTTTGAATTGACTGGTGGCCAATCCCGGGCTTTGACCGAAATTCTGGATGA
CATGAAATCTCCTTACCACATGAATCGGCTTTTGCAAGGTGATGTGGGATCTGGTAAGACAGTTGTCGCTTCGCTTTCAA
TGTATGCGGCTTGTCTGGCAAATTTTCAAGCAGCAATCATGGTTCCAACGGAAATTTTGGCTCGTCAGCATTTTGCAAAT
TTACAGGCGCTCTTTCCTGAGTTGCAAATCTCACTATTAGTTTCAGGCTTAAAAGCAGCTGAAAGACGGGAAATATTAGC
TGATTTAGCTAGTGGGCATACGCACATGGTAGTGGGAACGCATGCATTGATTCAAGAAGGAGTTGATTTTTATAACTTAG
GTCTAGTGATTACAGATGAACAACACCGTTTTGGGGTAAATCAGCGGAAAATTTTGCGGGAAAAAGGGCAAAATCCAGAT
GTATTAATGATGACGGCAACGCCAATTCCAAGAACGCTTGCGATTACGGCTTTTGGAGATATGGATGTTTCAATTATTGA
TGAACTGCCAAAGGGACGTCAACCCATTACCACAAGATGGGTCAAACATGAACAGTTTTCTGAAGTTTTAAGTTGGGTAA
AAGGTGAGGTTGCCAATGATTCTCAAGTCTATTTTATTTCACCATTGATTGAGGAGAGCGAAAGCCTAGACCTGAAAAAT
GCAGAAGCCTTATTTGCGGAATTAAATGACTACTTTGGTTTATTTGCCAAAATTGGGCTTTTACATGGAAAAATGAAAAA
TGATGAAAAAGACCAAATTATGCAAGAATTTAAGGCTAAAAAATTGGATGTTTTAGTGTCAACTACTGTAATCGAAGTAG
GGGTTGACGTGCCTAATGCCACCATCATGGTCATTATGGATGCTGACCGTTTTGGACTTTCACAACTTCATCAGTTACGG
GGACGTGTTGGTCGGGGAACAAAAAAATCTTACGCCATTTTAGTGGCAAATCCTAAGTCGGATTCAGGAAAACAACGGAT
GAAAATTATGACAGAGACGCAAAATGGTTTCGTTTTAGCCGAAGAAGATTTGAAAATGCGTGGTTCTGGGGAAATTTTTG
GACTTCGTCAATCAGGACTTCCAGAATTTATTGCGGCAGATTTGGTCAATGATTATAATATTTTAGAAGTAGCCAGACAA
GAAGCAGTTGAAATTTTTAAAAAGGCAGACGAGTTTCCTGATTTGATTGCGCAAGTGAACGTTGAGGGTGGATTTGACTG
A

Upstream 100 bases:

>100_bases
ACAGAGTATCTATCAGCAAAATTTACTGATAAAATACTCTGTCAGTAAATTATATTTGATTTTTGAAGCATTTAGCCTTA
TATCTTGGTATAATAAAAGT

Downstream 100 bases:

>100_bases
TGAATGAGAATGAATTGAATGATTTGATTTTGGATACTTGGTCCGATTTTGAAGAATTAAAAGTAAATCCCGAAAGTGCT
GAGGTCTTAATTCCGAACAG

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 666; Mature: 666

Protein sequence:

>666_residues
MKLTDSVQFLKGVGPKSVENFHKLGIFTVQDLLLYFPFRYEDFASRSVFELTDGEKATIIGTVVTPANVQYYGFKRNRLS
FKIKEGEAVVAVSFFNQPYLADKVEVGKEIAVYGKWEQTKQQLMGMKVVAQVDDGLEPVYHLTAGMKQSQLVKVIHQVFE
SGLLSELPENLPEFLIEKYRLMNRQEAVLAMHFPEDMAAHKQALRRVKFEELFMFQLKLQALKNKEKSGRAGLQVIFEQE
EIDKKISDLPFELTGGQSRALTEILDDMKSPYHMNRLLQGDVGSGKTVVASLSMYAACLANFQAAIMVPTEILARQHFAN
LQALFPELQISLLVSGLKAAERREILADLASGHTHMVVGTHALIQEGVDFYNLGLVITDEQHRFGVNQRKILREKGQNPD
VLMMTATPIPRTLAITAFGDMDVSIIDELPKGRQPITTRWVKHEQFSEVLSWVKGEVANDSQVYFISPLIEESESLDLKN
AEALFAELNDYFGLFAKIGLLHGKMKNDEKDQIMQEFKAKKLDVLVSTTVIEVGVDVPNATIMVIMDADRFGLSQLHQLR
GRVGRGTKKSYAILVANPKSDSGKQRMKIMTETQNGFVLAEEDLKMRGSGEIFGLRQSGLPEFIAADLVNDYNILEVARQ
EAVEIFKKADEFPDLIAQVNVEGGFD

Sequences:

>Translated_666_residues
MKLTDSVQFLKGVGPKSVENFHKLGIFTVQDLLLYFPFRYEDFASRSVFELTDGEKATIIGTVVTPANVQYYGFKRNRLS
FKIKEGEAVVAVSFFNQPYLADKVEVGKEIAVYGKWEQTKQQLMGMKVVAQVDDGLEPVYHLTAGMKQSQLVKVIHQVFE
SGLLSELPENLPEFLIEKYRLMNRQEAVLAMHFPEDMAAHKQALRRVKFEELFMFQLKLQALKNKEKSGRAGLQVIFEQE
EIDKKISDLPFELTGGQSRALTEILDDMKSPYHMNRLLQGDVGSGKTVVASLSMYAACLANFQAAIMVPTEILARQHFAN
LQALFPELQISLLVSGLKAAERREILADLASGHTHMVVGTHALIQEGVDFYNLGLVITDEQHRFGVNQRKILREKGQNPD
VLMMTATPIPRTLAITAFGDMDVSIIDELPKGRQPITTRWVKHEQFSEVLSWVKGEVANDSQVYFISPLIEESESLDLKN
AEALFAELNDYFGLFAKIGLLHGKMKNDEKDQIMQEFKAKKLDVLVSTTVIEVGVDVPNATIMVIMDADRFGLSQLHQLR
GRVGRGTKKSYAILVANPKSDSGKQRMKIMTETQNGFVLAEEDLKMRGSGEIFGLRQSGLPEFIAADLVNDYNILEVARQ
EAVEIFKKADEFPDLIAQVNVEGGFD
>Mature_666_residues
MKLTDSVQFLKGVGPKSVENFHKLGIFTVQDLLLYFPFRYEDFASRSVFELTDGEKATIIGTVVTPANVQYYGFKRNRLS
FKIKEGEAVVAVSFFNQPYLADKVEVGKEIAVYGKWEQTKQQLMGMKVVAQVDDGLEPVYHLTAGMKQSQLVKVIHQVFE
SGLLSELPENLPEFLIEKYRLMNRQEAVLAMHFPEDMAAHKQALRRVKFEELFMFQLKLQALKNKEKSGRAGLQVIFEQE
EIDKKISDLPFELTGGQSRALTEILDDMKSPYHMNRLLQGDVGSGKTVVASLSMYAACLANFQAAIMVPTEILARQHFAN
LQALFPELQISLLVSGLKAAERREILADLASGHTHMVVGTHALIQEGVDFYNLGLVITDEQHRFGVNQRKILREKGQNPD
VLMMTATPIPRTLAITAFGDMDVSIIDELPKGRQPITTRWVKHEQFSEVLSWVKGEVANDSQVYFISPLIEESESLDLKN
AEALFAELNDYFGLFAKIGLLHGKMKNDEKDQIMQEFKAKKLDVLVSTTVIEVGVDVPNATIMVIMDADRFGLSQLHQLR
GRVGRGTKKSYAILVANPKSDSGKQRMKIMTETQNGFVLAEEDLKMRGSGEIFGLRQSGLPEFIAADLVNDYNILEVARQ
EAVEIFKKADEFPDLIAQVNVEGGFD

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=681, Percent_Identity=38.7665198237885, Blast_Score=414, Evalue=1e-116,
Organism=Escherichia coli, GI1787357, Length=432, Percent_Identity=36.1111111111111, Blast_Score=264, Evalue=1e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 74796; Mature: 74796

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTDSVQFLKGVGPKSVENFHKLGIFTVQDLLLYFPFRYEDFASRSVFELTDGEKATII
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCEEEECCCCCEEEE
GTVVTPANVQYYGFKRNRLSFKIKEGEAVVAVSFFNQPYLADKVEVGKEIAVYGKWEQTK
EEEECCCCEEEEEEECCCEEEEEECCCEEEEEEECCCCCCCHHHHCCCEEEEECCHHHHH
QQLMGMKVVAQVDDGLEPVYHLTAGMKQSQLVKVIHQVFESGLLSELPENLPEFLIEKYR
HHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LMNRQEAVLAMHFPEDMAAHKQALRRVKFEELFMFQLKLQALKNKEKSGRAGLQVIFEQE
HCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHH
EIDKKISDLPFELTGGQSRALTEILDDMKSPYHMNRLLQGDVGSGKTVVASLSMYAACLA
HHHHHHHCCCEEECCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
NFQAAIMVPTEILARQHFANLQALFPELQISLLVSGLKAAERREILADLASGHTHMVVGT
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEH
HALIQEGVDFYNLGLVITDEQHRFGVNQRKILREKGQNPDVLMMTATPIPRTLAITAFGD
HHHHHCCCCEEEEEEEEECCHHHCCCCHHHHHHHCCCCCCEEEEECCCCCCEEEEEEECC
MDVSIIDELPKGRQPITTRWVKHEQFSEVLSWVKGEVANDSQVYFISPLIEESESLDLKN
CCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHCCCCCCCCCH
AEALFAELNDYFGLFAKIGLLHGKMKNDEKDQIMQEFKAKKLDVLVSTTVIEVGVDVPNA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEEEEEEEEECCCCCC
TIMVIMDADRFGLSQLHQLRGRVGRGTKKSYAILVANPKSDSGKQRMKIMTETQNGFVLA
EEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHEEEEECCCCEEEE
EEDLKMRGSGEIFGLRQSGLPEFIAADLVNDYNILEVARQEAVEIFKKADEFPDLIAQVN
CCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHEEE
VEGGFD
CCCCCC
>Mature Secondary Structure
MKLTDSVQFLKGVGPKSVENFHKLGIFTVQDLLLYFPFRYEDFASRSVFELTDGEKATII
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCEEEECCCCCEEEE
GTVVTPANVQYYGFKRNRLSFKIKEGEAVVAVSFFNQPYLADKVEVGKEIAVYGKWEQTK
EEEECCCCEEEEEEECCCEEEEEECCCEEEEEEECCCCCCCHHHHCCCEEEEECCHHHHH
QQLMGMKVVAQVDDGLEPVYHLTAGMKQSQLVKVIHQVFESGLLSELPENLPEFLIEKYR
HHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LMNRQEAVLAMHFPEDMAAHKQALRRVKFEELFMFQLKLQALKNKEKSGRAGLQVIFEQE
HCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHH
EIDKKISDLPFELTGGQSRALTEILDDMKSPYHMNRLLQGDVGSGKTVVASLSMYAACLA
HHHHHHHCCCEEECCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
NFQAAIMVPTEILARQHFANLQALFPELQISLLVSGLKAAERREILADLASGHTHMVVGT
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEH
HALIQEGVDFYNLGLVITDEQHRFGVNQRKILREKGQNPDVLMMTATPIPRTLAITAFGD
HHHHHCCCCEEEEEEEEECCHHHCCCCHHHHHHHCCCCCCEEEEECCCCCCEEEEEEECC
MDVSIIDELPKGRQPITTRWVKHEQFSEVLSWVKGEVANDSQVYFISPLIEESESLDLKN
CCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHCCCCCCCCCH
AEALFAELNDYFGLFAKIGLLHGKMKNDEKDQIMQEFKAKKLDVLVSTTVIEVGVDVPNA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEEEEEEEEECCCCCC
TIMVIMDADRFGLSQLHQLRGRVGRGTKKSYAILVANPKSDSGKQRMKIMTETQNGFVLA
EEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHEEEEECCCCEEEE
EEDLKMRGSGEIFGLRQSGLPEFIAADLVNDYNILEVARQEAVEIFKKADEFPDLIAQVN
CCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHEEE
VEGGFD
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8830261; 11463916 [H]