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The map label for this gene is rpiA

Identifier: 125625265

GI number: 125625265

Start: 2466170

End: 2466844

Strand: Reverse

Name: rpiA

Synonym: llmg_2511

Alternate gene names: 125625265

Gene position: 2466844-2466170 (Counterclockwise)

Preceding gene: 125625266

Following gene: 125625263

Centisome position: 97.52

GC content: 36.15

Gene sequence:

>675_bases
ATGGAAAATTTAAAAAAACAAGTTGGGATAAAAGCGGCTGAATTTGTTAAATCAGGAATGGTTGTTGGCTTAGGAACAGG
GTCAACAGCAGCCTATTTTGTAGAAGAATTAGGGAGAAGAGTTGCTGAAGAACAATTAGAAATTACGGGCGTGACAACTT
CTAGTGTGACAAGTGAACAAGCAAAAGCGCTGGGAATTCCTTTAGCTTCAATTGATGAAGTAGATTATGTTGACTTGACT
GTTGATGGAGCGGACGAAATTGATTCTCACTTGAATGGTATTAAAGGAGGAGGAGCGGCACTTTTAATGGAAAAAATCGT
TGCCACTTACTCAAAAGACTATATTTGGATTGTTGATGAGAGTAAATTATCAGAAAATCTTGGTTCTTTTAAAGTTCCAG
TAGAAGTTATTACTTATGGCTCAGAGCAATTATTTAAAGAGTTTGAAAGAGCTGCTTATGCTCCCACTTGGCGTTTAAAT
GAGGAGGGGGAGAAATTAATAACAGATATGCAACACTTTATTATTGACCTTCATATTGCAAAAATTGAAAATCCCCAAAA
ACTTGCTGATGAACTTGATTTAATGGTTGGAGTTGTGGAACATGGTCTCTTTAATGGTATGGTGAAAAAAGTGATTGTTG
CCGGTTCTGACGGAGTAAAAATAATAAGTCAATAA

Upstream 100 bases:

>100_bases
AAGAATATATTAGTTAATATAAATAAATAAAAAAGCTACTTTAAGTAGCTTTTTTGCTATAATTAAGTCAGCGTGATATC
GAAATATTCAAGGAGGTAAA

Downstream 100 bases:

>100_bases
AAAAAAATCGTCTTACTGACGATTTTTTTTATTTTTTCAACCATTCTTGAACTCCCCATTTATGGGAACCCCGTTTGAGT
TTGCTGATAGCTGTTTTTGG

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MENLKKQVGIKAAEFVKSGMVVGLGTGSTAAYFVEELGRRVAEEQLEITGVTTSSVTSEQAKALGIPLASIDEVDYVDLT
VDGADEIDSHLNGIKGGGAALLMEKIVATYSKDYIWIVDESKLSENLGSFKVPVEVITYGSEQLFKEFERAAYAPTWRLN
EEGEKLITDMQHFIIDLHIAKIENPQKLADELDLMVGVVEHGLFNGMVKKVIVAGSDGVKIISQ

Sequences:

>Translated_224_residues
MENLKKQVGIKAAEFVKSGMVVGLGTGSTAAYFVEELGRRVAEEQLEITGVTTSSVTSEQAKALGIPLASIDEVDYVDLT
VDGADEIDSHLNGIKGGGAALLMEKIVATYSKDYIWIVDESKLSENLGSFKVPVEVITYGSEQLFKEFERAAYAPTWRLN
EEGEKLITDMQHFIIDLHIAKIENPQKLADELDLMVGVVEHGLFNGMVKKVIVAGSDGVKIISQ
>Mature_224_residues
MENLKKQVGIKAAEFVKSGMVVGLGTGSTAAYFVEELGRRVAEEQLEITGVTTSSVTSEQAKALGIPLASIDEVDYVDLT
VDGADEIDSHLNGIKGGGAALLMEKIVATYSKDYIWIVDESKLSENLGSFKVPVEVITYGSEQLFKEFERAAYAPTWRLN
EEGEKLITDMQHFIIDLHIAKIENPQKLADELDLMVGVVEHGLFNGMVKKVIVAGSDGVKIISQ

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=236, Percent_Identity=33.0508474576271, Blast_Score=113, Evalue=2e-25,
Organism=Escherichia coli, GI1789280, Length=222, Percent_Identity=39.1891891891892, Blast_Score=145, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17551758, Length=232, Percent_Identity=35.3448275862069, Blast_Score=114, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6324669, Length=211, Percent_Identity=33.175355450237, Blast_Score=107, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281364072, Length=211, Percent_Identity=33.175355450237, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_LACLM (A2RP28)

Other databases:

- EMBL:   AM406671
- RefSeq:   YP_001033748.1
- ProteinModelPortal:   A2RP28
- SMR:   A2RP28
- STRING:   A2RP28
- GeneID:   4797489
- GenomeReviews:   AM406671_GR
- KEGG:   llm:llmg_2511
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   VFDLNSV
- ProtClustDB:   PRK00702
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 24364; Mature: 24364

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENLKKQVGIKAAEFVKSGMVVGLGTGSTAAYFVEELGRRVAEEQLEITGVTTSSVTSEQ
CCCHHHHHCCHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHH
AKALGIPLASIDEVDYVDLTVDGADEIDSHLNGIKGGGAALLMEKIVATYSKDYIWIVDE
HHHHCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEEC
SKLSENLGSFKVPVEVITYGSEQLFKEFERAAYAPTWRLNEEGEKLITDMQHFIIDLHIA
HHHHHCCCCEECCHHEEECCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KIENPQKLADELDLMVGVVEHGLFNGMVKKVIVAGSDGVKIISQ
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEECCC
>Mature Secondary Structure
MENLKKQVGIKAAEFVKSGMVVGLGTGSTAAYFVEELGRRVAEEQLEITGVTTSSVTSEQ
CCCHHHHHCCHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHH
AKALGIPLASIDEVDYVDLTVDGADEIDSHLNGIKGGGAALLMEKIVATYSKDYIWIVDE
HHHHCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEEC
SKLSENLGSFKVPVEVITYGSEQLFKEFERAAYAPTWRLNEEGEKLITDMQHFIIDLHIA
HHHHHCCCCEECCHHEEECCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KIENPQKLADELDLMVGVVEHGLFNGMVKKVIVAGSDGVKIISQ
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA