Click here to switch to the map view.

The map label for this gene is comGA [H]

Identifier: 125625167

GI number: 125625167

Start: 2346257

End: 2347237

Strand: Reverse

Name: comGA [H]

Synonym: llmg_2408

Alternate gene names: 125625167

Gene position: 2347237-2346257 (Counterclockwise)

Preceding gene: 125625168

Following gene: 125625166

Centisome position: 92.8

GC content: 37.1

Gene sequence:

>981_bases
ATGGTACAGAAAAAAGCACAAGAACTCATTCAAAAGGCAATTGAGATGGAGGCTTCTGATATTTATTTAATTGCTTCAGG
AAATCTTTATAAGATATATATTCGTCAACAATTAGGGCGAACTTTAATAGAGGAAGTTAACCAAGAGATTGGTTTAGCAT
TACTTACTCATTTTAAATTTCTTGCTGGCATGAATACTGGTGAACGCCGGCGTGTTCAGCTGGGTGCTTGTTGGTATGAA
CTAGAGGGAAGTTCGGCAAAACGTTTGCGCCTTTCAACAGTGGGAGATTTTGAAGGAAACGAATCATTGGTTATCCGTCT
TCTGCATGACCAAAAACAAGAACTTGAGTTTTGGTTTGATGATAAACTTCAGGATTTTCGATGTAAACGAGGACTTTATT
TATTTGCTGGGCCAGTAGGGTCTGGGAAAACTTCACTAATGTTTGACTTAGCCCACCGTCATTTTTCAAATGCACAGGTT
ATCACTATTGAGGAGCCTGTAGAATTAATTGATTCTGATTTTATTCAGTTACAAGTTAATGATGTAATTGGGAATAGTTA
TGATGAATTAATTAAACTTTCTTTAAGACACCGACCAGATTTACTAATTGTTGGAGAAATTCGAGATCAGCAGACAGCTC
GTGCTGTATTGCGTGCAAGTTTAACAGGCTATACAGTTTTTTCTACTATTCATGCGGCTTCCGTGAAGGGAGTGGTTCAA
CGTTTGTTGGAATTGGGTTTGAGTGATTGGGAATTAAAAAATGGATTAGAGGCAGTTGTTTATCAACGGTTAATAGCGGG
AAAAGGAGTATTAGATATTGCGAAAAGTAAATTTGACACTTGGTCGCCGAAAAAATGGAATGAAAAGATTGAGAACTTAT
ATGCAAACGGACATCTTACGGCTATTGAGGCCGAAAGGGAAAAAATTAGCATTAATCAAGCAAGCAAAATTGATACAACT
GATGGGGAATCTTTTGAATAA

Upstream 100 bases:

>100_bases
ATCGCTAGATTAGTCATTTATATTAAAAAAGTCGAAATATCTTCGACTTTTTTTGTACTATTTTTAGTTACATTTACTAA
CAAATTGCGTATATTCTAGT

Downstream 100 bases:

>100_bases
TGGTTTTAATTTGGGAGAAGTTATCAATTTTTTAGCCTTATCAAAATTAGTAGAAAAAGAGTTTGTATTCAAAATGCACC
AAGGTCTTAGTTCTGGAAAA

Product: putative competence protein ComGA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MVQKKAQELIQKAIEMEASDIYLIASGNLYKIYIRQQLGRTLIEEVNQEIGLALLTHFKFLAGMNTGERRRVQLGACWYE
LEGSSAKRLRLSTVGDFEGNESLVIRLLHDQKQELEFWFDDKLQDFRCKRGLYLFAGPVGSGKTSLMFDLAHRHFSNAQV
ITIEEPVELIDSDFIQLQVNDVIGNSYDELIKLSLRHRPDLLIVGEIRDQQTARAVLRASLTGYTVFSTIHAASVKGVVQ
RLLELGLSDWELKNGLEAVVYQRLIAGKGVLDIAKSKFDTWSPKKWNEKIENLYANGHLTAIEAEREKISINQASKIDTT
DGESFE

Sequences:

>Translated_326_residues
MVQKKAQELIQKAIEMEASDIYLIASGNLYKIYIRQQLGRTLIEEVNQEIGLALLTHFKFLAGMNTGERRRVQLGACWYE
LEGSSAKRLRLSTVGDFEGNESLVIRLLHDQKQELEFWFDDKLQDFRCKRGLYLFAGPVGSGKTSLMFDLAHRHFSNAQV
ITIEEPVELIDSDFIQLQVNDVIGNSYDELIKLSLRHRPDLLIVGEIRDQQTARAVLRASLTGYTVFSTIHAASVKGVVQ
RLLELGLSDWELKNGLEAVVYQRLIAGKGVLDIAKSKFDTWSPKKWNEKIENLYANGHLTAIEAEREKISINQASKIDTT
DGESFE
>Mature_326_residues
MVQKKAQELIQKAIEMEASDIYLIASGNLYKIYIRQQLGRTLIEEVNQEIGLALLTHFKFLAGMNTGERRRVQLGACWYE
LEGSSAKRLRLSTVGDFEGNESLVIRLLHDQKQELEFWFDDKLQDFRCKRGLYLFAGPVGSGKTSLMFDLAHRHFSNAQV
ITIEEPVELIDSDFIQLQVNDVIGNSYDELIKLSLRHRPDLLIVGEIRDQQTARAVLRASLTGYTVFSTIHAASVKGVVQ
RLLELGLSDWELKNGLEAVVYQRLIAGKGVLDIAKSKFDTWSPKKWNEKIENLYANGHLTAIEAEREKISINQASKIDTT
DGESFE

Specific function: Required for uptake of DNA by competent cells [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1786296, Length=275, Percent_Identity=31.6363636363636, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1789723, Length=268, Percent_Identity=31.3432835820896, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI87082188, Length=166, Percent_Identity=30.1204819277108, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 36976; Mature: 36976

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQKKAQELIQKAIEMEASDIYLIASGNLYKIYIRQQLGRTLIEEVNQEIGLALLTHFKF
CCHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGMNTGERRRVQLGACWYELEGSSAKRLRLSTVGDFEGNESLVIRLLHDQKQELEFWFD
HHCCCCCCCEEEEEEEEEEEECCCCCCEEEEEECCCCCCCHHEEEEEECCCHHHHHHHHC
DKLQDFRCKRGLYLFAGPVGSGKTSLMFDLAHRHFSNAQVITIEEPVELIDSDFIQLQVN
CCHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHCCCEEEEEEE
DVIGNSYDELIKLSLRHRPDLLIVGEIRDQQTARAVLRASLTGYTVFSTIHAASVKGVVQ
HHHCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
RLLELGLSDWELKNGLEAVVYQRLIAGKGVLDIAKSKFDTWSPKKWNEKIENLYANGHLT
HHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEE
AIEAEREKISINQASKIDTTDGESFE
EEECCCCEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVQKKAQELIQKAIEMEASDIYLIASGNLYKIYIRQQLGRTLIEEVNQEIGLALLTHFKF
CCHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGMNTGERRRVQLGACWYELEGSSAKRLRLSTVGDFEGNESLVIRLLHDQKQELEFWFD
HHCCCCCCCEEEEEEEEEEEECCCCCCEEEEEECCCCCCCHHEEEEEECCCHHHHHHHHC
DKLQDFRCKRGLYLFAGPVGSGKTSLMFDLAHRHFSNAQVITIEEPVELIDSDFIQLQVN
CCHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHCCCEEEEEEE
DVIGNSYDELIKLSLRHRPDLLIVGEIRDQQTARAVLRASLTGYTVFSTIHAASVKGVVQ
HHHCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
RLLELGLSDWELKNGLEAVVYQRLIAGKGVLDIAKSKFDTWSPKKWNEKIENLYANGHLT
HHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEE
AIEAEREKISINQASKIDTTDGESFE
EEECCCCEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2507524; 8969508; 9384377; 9422590; 9723928 [H]