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The map label for this gene is gmhB [H]

Identifier: 125625106

GI number: 125625106

Start: 2302378

End: 2302923

Strand: Reverse

Name: gmhB [H]

Synonym: llmg_2345

Alternate gene names: 125625106

Gene position: 2302923-2302378 (Counterclockwise)

Preceding gene: 125625107

Following gene: 125625105

Centisome position: 91.04

GC content: 36.81

Gene sequence:

>546_bases
ATGAGAAAAGCAATTTTCTTCGATCGTGATGGGACGCTCAATGAATTTAAACTAGGAGATTATATTATACAAGTTGAAGA
GCTTGTATTACTTAATGGAGCAGCAAGGGCAGTAAAAAAGGCCAATGCAGCGGGCTATTTGTGTATTATTGTTACCAATC
AAGGAGGAGTTATTCATAACAGAGGACTCGCTTATTCTGATGTTGAAAGAATAAATGAACGATTGGTCCAACTTTTGAAT
GAGGAGGGTGGCAAAATTGATGGAATTTATGTTTGTCCGCATTATCCTGGCTATGAGTCTTGTACATGCCGTAAACCCAA
AACTGGCTTGATTAATATGGCTGTGAGTGATTTCAGTATTAGTCTGAATAATTCATATATAATCGGGGATTCTGATTCTG
ATGTCTTGGCTGGAAAAAATGCAGGTCTTAAAACAGTAGGGATAGGTGAGCGAATAAAAACCGAGGCAGATTTTTGTACT
TATAATGTTGAAGAAGCGGTGAATTATATTTTGAAAAGAGAGAGTAAATGCCAAAAGTCAGTGTAA

Upstream 100 bases:

>100_bases
TGCATGTACCTATCAATGATATGCAAATCACTGAGGATATTCACCTTACTTTTAATCATATGATGATGTCTGTCTTTTAT
AAAAAGGTTGCGAATGAAAA

Downstream 100 bases:

>100_bases
TTGTACCTGTATACAATGTTGAAAAACTTTTAGAGAGATGTTTGAATTCTGTTCTCAATCAAAGCTTCCAGGATTTTGAG
TTGCTATTGATTGATGATGG

Product: histidinol-phosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MRKAIFFDRDGTLNEFKLGDYIIQVEELVLLNGAARAVKKANAAGYLCIIVTNQGGVIHNRGLAYSDVERINERLVQLLN
EEGGKIDGIYVCPHYPGYESCTCRKPKTGLINMAVSDFSISLNNSYIIGDSDSDVLAGKNAGLKTVGIGERIKTEADFCT
YNVEEAVNYILKRESKCQKSV

Sequences:

>Translated_181_residues
MRKAIFFDRDGTLNEFKLGDYIIQVEELVLLNGAARAVKKANAAGYLCIIVTNQGGVIHNRGLAYSDVERINERLVQLLN
EEGGKIDGIYVCPHYPGYESCTCRKPKTGLINMAVSDFSISLNNSYIIGDSDSDVLAGKNAGLKTVGIGERIKTEADFCT
YNVEEAVNYILKRESKCQKSV
>Mature_181_residues
MRKAIFFDRDGTLNEFKLGDYIIQVEELVLLNGAARAVKKANAAGYLCIIVTNQGGVIHNRGLAYSDVERINERLVQLLN
EEGGKIDGIYVCPHYPGYESCTCRKPKTGLINMAVSDFSISLNNSYIIGDSDSDVLAGKNAGLKTVGIGERIKTEADFCT
YNVEEAVNYILKRESKCQKSV

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI87082027, Length=143, Percent_Identity=30.7692307692308, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1786399, Length=187, Percent_Identity=28.8770053475936, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: 3.1.1.-

Molecular weight: Translated: 19935; Mature: 19935

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKAIFFDRDGTLNEFKLGDYIIQVEELVLLNGAARAVKKANAAGYLCIIVTNQGGVIHN
CCCEEEEECCCCCCEEECCCEEEEEEHEEEECCHHHHHHHCCCCCEEEEEEECCCCEEEC
RGLAYSDVERINERLVQLLNEEGGKIDGIYVCPHYPGYESCTCRKPKTGLINMAVSDFSI
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEE
SLNNSYIIGDSDSDVLAGKNAGLKTVGIGERIKTEADFCTYNVEEAVNYILKRESKCQKS
EECCEEEEECCCCCEEECCCCCEEEECCCCHHCCCCCEEEECHHHHHHHHHHHHHHHHCC
V
C
>Mature Secondary Structure
MRKAIFFDRDGTLNEFKLGDYIIQVEELVLLNGAARAVKKANAAGYLCIIVTNQGGVIHN
CCCEEEEECCCCCCEEECCCEEEEEEHEEEECCHHHHHHHCCCCCEEEEEEECCCCEEEC
RGLAYSDVERINERLVQLLNEEGGKIDGIYVCPHYPGYESCTCRKPKTGLINMAVSDFSI
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEE
SLNNSYIIGDSDSDVLAGKNAGLKTVGIGERIKTEADFCTYNVEEAVNYILKRESKCQKS
EECCEEEEECCCCCEEECCCCCEEEECCCCHHCCCCCEEEECHHHHHHHHHHHHHHHHCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12101286 [H]