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The map label for this gene is gmhA [H]

Identifier: 125625107

GI number: 125625107

Start: 2302920

End: 2303495

Strand: Reverse

Name: gmhA [H]

Synonym: llmg_2346

Alternate gene names: 125625107

Gene position: 2303495-2302920 (Counterclockwise)

Preceding gene: 125625108

Following gene: 125625106

Centisome position: 91.07

GC content: 34.03

Gene sequence:

>576_bases
ATGAATTATACAGAAGAAATCACAAACTATTACGCACGTCTTGAAAAAACAATAGAATCACTTGATAAAGAAGCACTGAA
TCAGGTGATGAATCTTTTACAAGATGCCTATAAAAAGGAGTCAAGAATTTATGTTTGTGGAAATGGTGGAAGTGCCAGTA
CTGCCTCTCACTTAATGAATGACTTTAACAAAGGACTCTCATATGATCAAGAGAAAAAATGGCATGTCGTTTCTTTGAAC
GATAACGTGGCAACTTTGATGGCTATTTCCAATGATGATAGTTATGACAAGGTATTTTCAAAACAACTTGAGGGAAATAT
CACAAAAGATGACATTCTTCTTGCGATTTCTGGAAGCGGAAATTCAAAAAATATAATTGAGGCGGTTAAAGAGGCTCAAA
AAGTGGGAGCTAAAGTCGTTGGAATGACAGGTTATGATGGAGGAAAACTTTATCAAATGAGCGATTTTAATATGCATGTA
CCTATCAATGATATGCAAATCACTGAGGATATTCACCTTACTTTTAATCATATGATGATGTCTGTCTTTTATAAAAAGGT
TGCGAATGAAAAATGA

Upstream 100 bases:

>100_bases
GATACCGAAGGAACTAAAGTCATTTATGAGGAAAAATAAAAGCCGTATATTTCTACTAATAAAATGATTATCAGCTATGC
ATAGCAAAAGGAGAAATTAA

Downstream 100 bases:

>100_bases
GAAAAGCAATTTTCTTCGATCGTGATGGGACGCTCAATGAATTTAAACTAGGAGATTATATTATACAAGTTGAAGAGCTT
GTATTACTTAATGGAGCAGC

Product: GmhA protein

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MNYTEEITNYYARLEKTIESLDKEALNQVMNLLQDAYKKESRIYVCGNGGSASTASHLMNDFNKGLSYDQEKKWHVVSLN
DNVATLMAISNDDSYDKVFSKQLEGNITKDDILLAISGSGNSKNIIEAVKEAQKVGAKVVGMTGYDGGKLYQMSDFNMHV
PINDMQITEDIHLTFNHMMMSVFYKKVANEK

Sequences:

>Translated_191_residues
MNYTEEITNYYARLEKTIESLDKEALNQVMNLLQDAYKKESRIYVCGNGGSASTASHLMNDFNKGLSYDQEKKWHVVSLN
DNVATLMAISNDDSYDKVFSKQLEGNITKDDILLAISGSGNSKNIIEAVKEAQKVGAKVVGMTGYDGGKLYQMSDFNMHV
PINDMQITEDIHLTFNHMMMSVFYKKVANEK
>Mature_191_residues
MNYTEEITNYYARLEKTIESLDKEALNQVMNLLQDAYKKESRIYVCGNGGSASTASHLMNDFNKGLSYDQEKKWHVVSLN
DNVATLMAISNDDSYDKVFSKQLEGNITKDDILLAISGSGNSKNIIEAVKEAQKVGAKVVGMTGYDGGKLYQMSDFNMHV
PINDMQITEDIHLTFNHMMMSVFYKKVANEK

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1786416, Length=164, Percent_Identity=30.4878048780488, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1789539, Length=184, Percent_Identity=31.5217391304348, Blast_Score=91, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 21503; Mature: 21503

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYTEEITNYYARLEKTIESLDKEALNQVMNLLQDAYKKESRIYVCGNGGSASTASHLMN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
DFNKGLSYDQEKKWHVVSLNDNVATLMAISNDDSYDKVFSKQLEGNITKDDILLAISGSG
HHHHCCCCCCCCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEEEECCC
NSKNIIEAVKEAQKVGAKVVGMTGYDGGKLYQMSDFNMHVPINDMQITEDIHLTFNHMMM
CCHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCEEECCCCCEEECHHHHHHHHHHHH
SVFYKKVANEK
HHHHHHHCCCC
>Mature Secondary Structure
MNYTEEITNYYARLEKTIESLDKEALNQVMNLLQDAYKKESRIYVCGNGGSASTASHLMN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
DFNKGLSYDQEKKWHVVSLNDNVATLMAISNDDSYDKVFSKQLEGNITKDDILLAISGSG
HHHHCCCCCCCCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEEEECCC
NSKNIIEAVKEAQKVGAKVVGMTGYDGGKLYQMSDFNMHVPINDMQITEDIHLTFNHMMM
CCHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCEEECCCCCEEECHHHHHHHHHHHH
SVFYKKVANEK
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA