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The map label for this gene is ftsZ [H]

Identifier: 125624832

GI number: 125624832

Start: 2042201

End: 2043460

Strand: Reverse

Name: ftsZ [H]

Synonym: llmg_2060

Alternate gene names: 125624832

Gene position: 2043460-2042201 (Counterclockwise)

Preceding gene: 125624833

Following gene: 125624831

Centisome position: 80.79

GC content: 40.48

Gene sequence:

>1260_bases
ATGGAATTTTCATTTGATACAGACTTAACTTCTGGTGCTGTAATTAAAGTTATCGGTGTTGGTGGTGGTGGTGGTAATGC
CATCAACCGTATGATTGAAGAAGGTGTTTCTGGCGTTGAATTTATCGCTGCAAACACTGATGTACAAGCTTTGCGTAGTT
CAAAAGCAGATACAGTAATTCAACTTGGCCCAAAATTGACTCGTGGTTTGGGTGCTGGTGCACAACCTGAAGTAGGTAAA
CGTGCAGCTGAAGAATCAGCTGAAACTGTTTCACAAGCCCTTGAAGGATCAGATATGATTTTCATCACTGCTGGTATGGG
TGGTGGAACTGGTACAGGTGCTGCACCAGTTATTGCTCAAATCGCTAAAGAACTTGGTGCTTTGACTGTCGGTGTTGTTA
CTCGTCCTTTCGGTTTCGAAGGTTCAAAACGTTCATATTTTGCAACAGAAGGAATTGAAGCTCTTCGTGCAAATGTTGAT
ACGCTTCTTATCATCTCAAACAACAACTTGCTTGAAATTGTTGATAAGAAAACTCCATTGACTGAAGCATTACGTGAGGC
TGATAATGTTTTGCGCCAAGGTGTTCAAGGGGTTACTGATTTGATTACTAACCCAGGAATGATTAACCTTGACTTTGCCG
ATGTTAAAACAGTCATGGAAAATAAAGGTGATGCTCTTATGGGTATCGGAGTTGCGACTGGTGAAGAACGAGTTATCGAA
GCAACTCGCAAAGCGATCTACTCACCACTTCTTGAAACTACAATTGAAGGAGCTGAAAATGTTCTTTTGAATGTGACAGG
TGGAATGGATATGAGTTTGATTGAAGCACAAGATGCTTCAGAAATTGTTATCCAAGCAGCTGGTAATGATGTTAATATTA
TGTTAGGTACAGCAATTGATCCTAACCTTAAAGATGAAATCCGTGTAACAGTTGTTGCAACTGGTGTTGCTAAAGAAGAT
GCAGATGAAGCTTTGGGATTGCAACCAGAATCACGTCGTCAACCTAATTTGACACATAATTCTAATATGCAACATGCTCA
AACAAGTCGTCCAATGCAAAGTCAACAACAACCGCAAGCGACTCAACAAGGACAAAATCAATCTTCAGCATTTGGAGATT
GGGATATTCGCCGTGAAACTTCAACACGTCAAAACGTAAGTAACACACGCGATACTTCTTCAGTAACAAGTTTTGGTGGA
GTACCAACTACAGATGAAGACCTTGATACACCACCATTCTTCCGTAAAATTAATCTATGA

Upstream 100 bases:

>100_bases
CTGAGCCCGAAGAAGAAAAAGAAGGTCTTGTTGACCGTGCCAAAAGTTTCTTTGGCAACCTCTTTGACTAATCTGAAAGT
AAAAACGGAGAAATAAAAAC

Downstream 100 bases:

>100_bases
CGATTAAAGAGAATGTTAAAAGAATACTGAATAATGTGGATGCAGCAAAAGCTGCGTCTTCTTATTCTAATCAGTCAGTT
TCAGTCGTTGCTGTAACAAA

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MEFSFDTDLTSGAVIKVIGVGGGGGNAINRMIEEGVSGVEFIAANTDVQALRSSKADTVIQLGPKLTRGLGAGAQPEVGK
RAAEESAETVSQALEGSDMIFITAGMGGGTGTGAAPVIAQIAKELGALTVGVVTRPFGFEGSKRSYFATEGIEALRANVD
TLLIISNNNLLEIVDKKTPLTEALREADNVLRQGVQGVTDLITNPGMINLDFADVKTVMENKGDALMGIGVATGEERVIE
ATRKAIYSPLLETTIEGAENVLLNVTGGMDMSLIEAQDASEIVIQAAGNDVNIMLGTAIDPNLKDEIRVTVVATGVAKED
ADEALGLQPESRRQPNLTHNSNMQHAQTSRPMQSQQQPQATQQGQNQSSAFGDWDIRRETSTRQNVSNTRDTSSVTSFGG
VPTTDEDLDTPPFFRKINL

Sequences:

>Translated_419_residues
MEFSFDTDLTSGAVIKVIGVGGGGGNAINRMIEEGVSGVEFIAANTDVQALRSSKADTVIQLGPKLTRGLGAGAQPEVGK
RAAEESAETVSQALEGSDMIFITAGMGGGTGTGAAPVIAQIAKELGALTVGVVTRPFGFEGSKRSYFATEGIEALRANVD
TLLIISNNNLLEIVDKKTPLTEALREADNVLRQGVQGVTDLITNPGMINLDFADVKTVMENKGDALMGIGVATGEERVIE
ATRKAIYSPLLETTIEGAENVLLNVTGGMDMSLIEAQDASEIVIQAAGNDVNIMLGTAIDPNLKDEIRVTVVATGVAKED
ADEALGLQPESRRQPNLTHNSNMQHAQTSRPMQSQQQPQATQQGQNQSSAFGDWDIRRETSTRQNVSNTRDTSSVTSFGG
VPTTDEDLDTPPFFRKINL
>Mature_419_residues
MEFSFDTDLTSGAVIKVIGVGGGGGNAINRMIEEGVSGVEFIAANTDVQALRSSKADTVIQLGPKLTRGLGAGAQPEVGK
RAAEESAETVSQALEGSDMIFITAGMGGGTGTGAAPVIAQIAKELGALTVGVVTRPFGFEGSKRSYFATEGIEALRANVD
TLLIISNNNLLEIVDKKTPLTEALREADNVLRQGVQGVTDLITNPGMINLDFADVKTVMENKGDALMGIGVATGEERVIE
ATRKAIYSPLLETTIEGAENVLLNVTGGMDMSLIEAQDASEIVIQAAGNDVNIMLGTAIDPNLKDEIRVTVVATGVAKED
ADEALGLQPESRRQPNLTHNSNMQHAQTSRPMQSQQQPQATQQGQNQSSAFGDWDIRRETSTRQNVSNTRDTSSVTSFGG
VPTTDEDLDTPPFFRKINL

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=336, Percent_Identity=47.6190476190476, Blast_Score=279, Evalue=2e-76,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 44262; Mature: 44262

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS01134 FTSZ_1 ; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFSFDTDLTSGAVIKVIGVGGGGGNAINRMIEEGVSGVEFIAANTDVQALRSSKADTVI
CCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCEEE
QLGPKLTRGLGAGAQPEVGKRAAEESAETVSQALEGSDMIFITAGMGGGTGTGAAPVIAQ
ECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHH
IAKELGALTVGVVTRPFGFEGSKRSYFATEGIEALRANVDTLLIISNNNLLEIVDKKTPL
HHHHHCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCH
TEALREADNVLRQGVQGVTDLITNPGMINLDFADVKTVMENKGDALMGIGVATGEERVIE
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCEEEEEEECCCHHHHHH
ATRKAIYSPLLETTIEGAENVLLNVTGGMDMSLIEAQDASEIVIQAAGNDVNIMLGTAID
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCEEEEEECCCCEEEEEECCCC
PNLKDEIRVTVVATGVAKEDADEALGLQPESRRQPNLTHNSNMQHAQTSRPMQSQQQPQA
CCCCCCEEEEEEEECCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHCCCCH
TQQGQNQSSAFGDWDIRRETSTRQNVSNTRDTSSVTSFGGVPTTDEDLDTPPFFRKINL
HHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCCCCEECCC
>Mature Secondary Structure
MEFSFDTDLTSGAVIKVIGVGGGGGNAINRMIEEGVSGVEFIAANTDVQALRSSKADTVI
CCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCEEE
QLGPKLTRGLGAGAQPEVGKRAAEESAETVSQALEGSDMIFITAGMGGGTGTGAAPVIAQ
ECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHH
IAKELGALTVGVVTRPFGFEGSKRSYFATEGIEALRANVDTLLIISNNNLLEIVDKKTPL
HHHHHCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCH
TEALREADNVLRQGVQGVTDLITNPGMINLDFADVKTVMENKGDALMGIGVATGEERVIE
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCEEEEEEECCCHHHHHH
ATRKAIYSPLLETTIEGAENVLLNVTGGMDMSLIEAQDASEIVIQAAGNDVNIMLGTAID
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCEEEEEECCCCEEEEEECCCC
PNLKDEIRVTVVATGVAKEDADEALGLQPESRRQPNLTHNSNMQHAQTSRPMQSQQQPQA
CCCCCCEEEEEEEECCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHCCCCH
TQQGQNQSSAFGDWDIRRETSTRQNVSNTRDTSSVTSFGGVPTTDEDLDTPPFFRKINL
HHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9287029; 12663927 [H]