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The map label for this gene is sdaA [H]

Identifier: 125624523

GI number: 125624523

Start: 1710037

End: 1710900

Strand: Reverse

Name: sdaA [H]

Synonym: llmg_1732

Alternate gene names: 125624523

Gene position: 1710900-1710037 (Counterclockwise)

Preceding gene: 125624524

Following gene: 125624522

Centisome position: 67.64

GC content: 42.59

Gene sequence:

>864_bases
ATGTTTAAAAATATAGAAGAATTAATCGAGGATTCTAAAAATTATTCCTCGGTCACAGAATTAATGATTGCCATTGAAAT
GGAACAAACTGGACGAAATCGTGAACAAATTTGGGAAATGATGGAACATAACCTAGAAACGATGCTTGATTCTGTTAAAA
AAGGATTGGTTGGGAAAAAATCACTGACAGGTTTGACTGGTGGTGATGCAAAATTAATGGATGACTACATTCAATCAGGG
AAAGCTTTGTCAGGAGATATTATTTTAGGAGCTGCGCGTGATGCAGTTGCGGTAAATGAGGTCAATGCCCAAATGGGTCT
GATTTGCGCTACTCCAACTGCTGGTTCCGCTGGATGTTTACCGGGGGTCTTAACTTCGGCAATTAAAACATTAGGTTTGA
CACATGAGCAACAAGTCGAATTTCTATTTGTTGCTGGAGCTTTTGGTCTAGCAATTGCTAATAACGCCACAATCTCGGGT
GCCGAGGGAGGATGTCAAGCGGAAGTTGGTTCAGCCTCAGCAATGGCTTCGGCTGCTCTTGTTCTTGCTGCAGGAGGTTC
TGCTGAGCAAGCAGGTTATGCAATTGCCATTGTTTTACAAAATATGTTAGGATTGATTTGTGACCCTGTTGCTGGTCTGG
TCGAAATTCCCTGTGTTCACCGTAATGCAATGGGCGCTTCACAAGCGATGATATCAGCTGATATGGCTTTGGCCGGAGTC
AAAACAGTAATTCCAGTCGATGAAGTTGTGAATACAATGTATAATGTCGGGCGCTCTTTACCAGCAGCTTTTAGAGAAAC
AGCCGAAGGCGGATTGGCTCAGACAACCACCGGACGTAAGATTATGGAAGAATTATTTGGTTAA

Upstream 100 bases:

>100_bases
GTTGATATACCAAATGTTAAGGAAGTAATTGAGGAAATGAAACTTATTCCTCGTTTGCACGCCGTTAATTTCTTTAATTA
AAAGCAGTATAGGAATAAAT

Downstream 100 bases:

>100_bases
GATTAAACTTAAAGATTCGAATATGAGATTCGAATCTTTATTTTTTTGAGTTGAATACTTGACTTTTAGTGTTTACACGT
GTAAACTTATTTTATGAAAA

Product: L-serine dehydratase alpha subunit

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MFKNIEELIEDSKNYSSVTELMIAIEMEQTGRNREQIWEMMEHNLETMLDSVKKGLVGKKSLTGLTGGDAKLMDDYIQSG
KALSGDIILGAARDAVAVNEVNAQMGLICATPTAGSAGCLPGVLTSAIKTLGLTHEQQVEFLFVAGAFGLAIANNATISG
AEGGCQAEVGSASAMASAALVLAAGGSAEQAGYAIAIVLQNMLGLICDPVAGLVEIPCVHRNAMGASQAMISADMALAGV
KTVIPVDEVVNTMYNVGRSLPAAFRETAEGGLAQTTTGRKIMEELFG

Sequences:

>Translated_287_residues
MFKNIEELIEDSKNYSSVTELMIAIEMEQTGRNREQIWEMMEHNLETMLDSVKKGLVGKKSLTGLTGGDAKLMDDYIQSG
KALSGDIILGAARDAVAVNEVNAQMGLICATPTAGSAGCLPGVLTSAIKTLGLTHEQQVEFLFVAGAFGLAIANNATISG
AEGGCQAEVGSASAMASAALVLAAGGSAEQAGYAIAIVLQNMLGLICDPVAGLVEIPCVHRNAMGASQAMISADMALAGV
KTVIPVDEVVNTMYNVGRSLPAAFRETAEGGLAQTTTGRKIMEELFG
>Mature_287_residues
MFKNIEELIEDSKNYSSVTELMIAIEMEQTGRNREQIWEMMEHNLETMLDSVKKGLVGKKSLTGLTGGDAKLMDDYIQSG
KALSGDIILGAARDAVAVNEVNAQMGLICATPTAGSAGCLPGVLTSAIKTLGLTHEQQVEFLFVAGAFGLAIANNATISG
AEGGCQAEVGSASAMASAALVLAAGGSAEQAGYAIAIVLQNMLGLICDPVAGLVEIPCVHRNAMGASQAMISADMALAGV
KTVIPVDEVVNTMYNVGRSLPAAFRETAEGGLAQTTTGRKIMEELFG

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=280, Percent_Identity=35.7142857142857, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789161, Length=183, Percent_Identity=44.2622950819672, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI48994925, Length=247, Percent_Identity=36.8421052631579, Blast_Score=135, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005130
- InterPro:   IPR004642 [H]

Pfam domain/function: PF03313 SDH_alpha [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 29718; Mature: 29718

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKNIEELIEDSKNYSSVTELMIAIEMEQTGRNREQIWEMMEHNLETMLDSVKKGLVGKK
CCCCHHHHHHCCCCHHHHHHHHHHEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
SLTGLTGGDAKLMDDYIQSGKALSGDIILGAARDAVAVNEVNAQMGLICATPTAGSAGCL
HCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHCCCEEEEEECCCCCCCCCH
PGVLTSAIKTLGLTHEQQVEFLFVAGAFGLAIANNATISGAEGGCQAEVGSASAMASAAL
HHHHHHHHHHHCCCCHHHHHEEEEECHHHHHEECCCEECCCCCCCCCCCCCHHHHHHHHH
VLAAGGSAEQAGYAIAIVLQNMLGLICDPVAGLVEIPCVHRNAMGASQAMISADMALAGV
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHH
KTVIPVDEVVNTMYNVGRSLPAAFRETAEGGLAQTTTGRKIMEELFG
HHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MFKNIEELIEDSKNYSSVTELMIAIEMEQTGRNREQIWEMMEHNLETMLDSVKKGLVGKK
CCCCHHHHHHCCCCHHHHHHHHHHEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
SLTGLTGGDAKLMDDYIQSGKALSGDIILGAARDAVAVNEVNAQMGLICATPTAGSAGCL
HCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHCCCEEEEEECCCCCCCCCH
PGVLTSAIKTLGLTHEQQVEFLFVAGAFGLAIANNATISGAEGGCQAEVGSASAMASAAL
HHHHHHHHHHHCCCCHHHHHEEEEECHHHHHEECCCEECCCCCCCCCCCCCHHHHHHHHH
VLAAGGSAEQAGYAIAIVLQNMLGLICDPVAGLVEIPCVHRNAMGASQAMISADMALAGV
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHH
KTVIPVDEVVNTMYNVGRSLPAAFRETAEGGLAQTTTGRKIMEELFG
HHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]